To learn more about cellular immunotherapy, and start your journey to receiving exceptional care, contact Moffitt at 1-888-663-3488 or complete a new patient registration form  online.
World Leader in Cellular Immunotherapy
You can feel secure putting your trust in Moffitt Cancer Center. Every year thousands of patients across the country travel to Florida to seek treatment at Moffitt. Our experts lead the way in cellular immunotherapy research and treatment for blood cancers, and they are pioneering new treatments like tumor infiltrating lymphocytes (TILS) and T cell receptor (TCR) therapy as well as the use of immunotherapy in solid tumors. These groundbreaking innovations in immunotherapy have had a huge impact on patient outcomes.
We now have patients, who had no other viable treatment options at the time, who are in ongoing complete remission six years later after a single infusion of CAR T cells.
What is cell therapy?
Cell therapy is a novel treatment that uses the body’s own immune system to enhance its ability to find and target cancerous cells. Moffitt offers several types of cellular immunotherapy, including chimeric antigen receptor (CAR) T-cell therapy, T-cell receptor (TCR) therapy, tumor-infiltrating lymphocytes (TIL) therapy, dendritic cell vaccine.
Moffitt has been a driving force in getting several cellular immunotherapies FDA-approved and continues to lead in expanding immunotherapy options for patients. Some FDA immunotherapy approvals include:
- Lifileucel (Amtagvi™) for the treatment of individuals with unresectable or metastatic melanoma previously treated with a PD-1 blocking antibody, and if BRAF V600 positive, a BRAF inhibitor with or without a MEK inhibitor.
- Zxicabtagene ciloleucel (Yescarta) for the treatment of adult patients with large B-cell lymphoma that is refractory to first-line chemoimmunotherapy or that relapses within 12 months of first-line chemoimmunotherapy.
- Idecabtagene vicleucel (Abecma) for individuals with multiple myeloma that either hasn’t responded to or has returned after at least four different prior cancer treatments.
- Ciltacabtagene autoleucel (Carvykti) for adults with multiple myeloma that either isn’t responding to treatment or has returned after receiving at least four lines of cancer therapy.
- Pembrolizumab (Keytruda) an immune checkpoint inhibitor immunotherapy used for 16 types of cancer including certain types of triple negative breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer and others
- Lisocabtagene maraleucel (Breyanzi) for the treatment of large B cell lymphoma when the first treatment has not worked or the cancer returned within a year of the first treatment; OR the first treatment has not worked or the cancer returned after the first treatment, and the patient is not eligible for hematopoietic stem cell transplantation because of medical conditions or age; OR two or more kinds of treatment have not worked or stopped working. It is also for the treatment of chronic lymphocytic leukemia or small lymphocytic lymphoma when two or more kinds of treatment have not worked or stopped working.
A team of experts dedicated to you
Not only is Moffitt a world-leader in developing and using immunotherapies, we are also the first center in the country to develop a dedicated Immune Cell Therapy (ICE-T) unit. The state-of-the-art unit gives patients and caregivers a better treatment experience, including a team of experts entirely dedicated to cellular immunotherapy treatment, personally guiding patients every step of the way. This means throughout your entire treatment you will come to the same place - and see the same team - from start to finish.
Who can be treated with immunotherapy?
Patients with certain types of cancers who have not had success with other lines of therapy may be candidates for immunotherapy.
Those with the following types of cancers can be treated with immunotherapy at Moffitt:
I got a phone call from my oncologist and he said ‘Just go to Tampa, you’re going to go Moffitt’ and that’s when I was introduced to immunotherapy. Once I tried the CAR T therapy, I came out a winner.
Dimas, Non-Hodgkin Lymphoma Survivor
Why should I travel to Florida for my care?
Making a trip to Tampa, Florida to receive cellular immunotherapy cancer treatment at Moffitt can be a life-changing experience. As our patient you can expect:
- State-of-the-art Immune Cell Therapy unit (ICE-T), with a dedicated team, 12 inpatient beds and 8 treatment bays for outpatient visits, giving patients and caregivers a better treatment experience
- Opportunities to take part in clinical trials, developed by our world-renowned scientists and doctors, only available at Moffitt
- An expert team of medical professionals working together to develop a personalized treatment plan
- Convenience of all your medical appointments and treatments happening in a single location
- Access to the most advanced technology and treatment combinations
Moffitt is relentless in its mission to prevent, treat and cure cancer. Our patients have unmatched support and more treatment options. More hope. And exceptional outcomes. 
