Triple Negative Breast Cancer Treatment Information

Triple negative breast cancer treatment options are being evaluated by medical researchers and clinicians as more is being learned about triple negative cancers. These cancers, which comprise approximately 15 percent of all breast cancer cases, are differentiated by several key characteristics. Most notably, when triple negative cell samples are analyzed in a lab, the pathology results reveal an absence of three hormone receptors: estrogen, progesterone and HER-2/neu. These hormone receptors usually exist in healthy breast cells.

Our Approach

A triple negative finding is a significant consideration when formulating a treatment plan. The reason is that traditional hormone-based therapies like tamoxifen and Herceptin, which are often helpful for treating hormone-receptive breast cancers, have no effect on triple negative breast cancer. Typically, triple negative breast cancer is treated with one or more of the following methods:

  • Surgery – A procedures like lumpectomy or mastectomy can be used to remove as much of a tumor as possible.
  • Radiation therapy – Targeted, high-energy rays are used to destroy breast cancer cells.
  • Chemotherapy – Drugs are administered to destroy rapidly dividing cancer cells.
  • Neoadjuvant therapy – Chemotherapy or radiation therapy is administered prior to surgery, or vice versa.

Some patients wonder whether triple negative breast cancer should be treated more aggressively than other types of breast cancer. This is not necessarily the case. In fact, some researchers believe that triple negative breast cancer responds more favorably to chemotherapy than hormone-receptive cancers.

At Moffitt Cancer Center, we continue to make strides in developing our understanding of triple negative breast cancer. Our extensive research efforts and innovative clinical trials have led to patient outcomes that consistently outrank national averages and help our patients lead healthy and productive lives.

If you are interested in learning more about triple negative breast cancer treatment at Moffitt, call 1-888-MOFFITT or schedule an appointment online. You don’t need a referral to consult with our experienced oncologists specializing in breast cancer.