The Tissue Core (TC) is the central biorepository for Moffitt Cancer Center. The overall goal of the TC is to collect, process, store, and release high-quality, well-annotated biospecimens in support of research.
To accomplish its goal, the TC’s Specific Aims are to:
Aim 1: Serve as the centralized MCC biobanking resource for the collection, processing, and storage of human biospecimens in support of member science.
Aim 2: Implement biorepository best practices and quality metrics that ensure members’ access to high-quality biospecimens.
Aim 3: Develop and promote policies, guidelines, and procedures that facilitate members’ efficient access to human biospecimens in a regulatory-compliant manner.
Tissue Core services are housed within three distinct sections:
- Intake & Acquisition: Collection, initial annotation, and de-identification of biospecimens for investigator-driven and general banking protocols.
- Sample Processing Lab: Biospecimen processing services ranging from processing of blood to extraction of nucleic acids.
- Research Histology Services: Basic histology services, research-focused immunohistochemistry, and construction of tissue microarrays.
Overall, the TC offers 81 distinct biobanking and biospecimen-related services that meet or exceed NCI best practice recommendations and College of American Pathologists (CAP) Biorepository Accreditation standards to ensure high-quality biospecimen collection and processing validated through standardization, documentation, and emphasis on quality management.
Anthony Magliocco, MD
Director - Edward Seijo
Manager - Michelle Fournier
Quality Management Coordinator:
Intake and Acquisition:
Staff Scientist - Kristin Morrow
Staff Scientist - Jeanette Rheinhardt
Pathologist - Alex Lopez, MD
Staff Scientist - Marek Wloch
Total Cancer Care Lab:
Pathologist - Stephen Brantley
The core is supported in part by the National Cancer Institute (P30-CA076292, Cancer Center Support Grant).