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Rob JB Macaulay, MD

Specialty: Pathology
Program: Pathology

Call 1-888-MOFFITT

Call 1-888-MOFFITT

Locations: Moffitt Cancer Center

Cancer Types Treated: Meningioma , Neurofibromatosis , Spinal Tumor , Brain Cancer , Glioblastoma

Dr. Macaulay joined the Department of Anatomic Pathology at Moffitt in the summer of 2014, with a joint appointment as Full Professor at the Morsani College of Medicine, USF.  His shift to the Moffitt was motivated by a desire to contribute more directly to advancements in neuro-oncology, particularly in molecular pathology. He is heavily engaged in providing clinical neuropathology service, fellow/resident teaching, and administrative duties, similar to his role as a member of the Department of Pathology at Dalhousie University from 1999-2014. He has been involved in professional activities both at the local level and on the national stage. His research activities are directed at biology and classification of primary brain tumors, particularly infiltrative gliomas.  

Education & Training


  • University of Toronto - Neuropathology

Medical School:

  • Queen's University - MD
Participating Trials

Neurofibroma and MPNST Tumor Progression in Neurofibromatosis Type 1 (NF1) -- Genomic, Histological and Clinical Analysis, an NF Research MPNST Genomic Consortium (GeM) Project: Part 2 -- Prospective Recruitment, Tissue Collection, and Analysis
Condition: Neurologic Oncology

Benign Neurofibroma and MPNST Tumor Progression in Neurofibromatosis Type 1 (NF1) - Evolution of the Growth Factor Receptor and Hormonal Receptor Expression
Condition: Neurologic Oncology

Clinical Study of the Utility of a Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas
Condition: Neurologic Oncology
Intervention: 5-ALA

If you believe you are eligible for one of these trials or studies, please call
813-745-6100 or toll-free 1-800-679-0775.


  • Perkins AR, Macaulay RJB, Bui MM, Bridge JA, Etame AB. A Frontal Dural-Based Lesion in a 63-Year Old Male. Brain Pathol. 2019 Mar;29(2):301-302. Pubmedid: 30821029.
  • Wang D, Berglund AE, Kenchappa RS, MacAulay RJ, Mulé JJ, Etame AB. BIRC3 is a biomarker of mesenchymal habitat of glioblastoma, and a mediator of survival adaptation in hypoxia-driven glioblastoma habitats. Sci Rep. 2017 Aug;7(1):9350. Pubmedid: 28839258. Pmcid: PMC5570925.
  • Sinha N, Wooff J, Shankar JJ, Gorman P, Macaulay RJ. 48 year-old woman with right leg and arm numbness. Brain Pathol. 2015 Jan;25(1):109-110. Pubmedid: 25521181.
  • Macaulay RJ. Impending Impact of Molecular Pathology on Classifying Adult Diffuse Gliomas. Cancer Control. 2015 Apr;22(2):200-205. Pubmedid: 26068765.
  • Coras R, de Boer OJ, Armstrong D, Becker A, Jacques TS, Miyata H, Thom M, Vinters HV, Spreafico R, Oz B, Marucci G, Pimentel J, Mühlebner A, Zamecnik J, Buccoliero AM, Rogerio F, Streichenberger N, Arai N, Bugiani M, Vogelgesang S, Macaulay R, Salon C, Hans V, Polivka M, Giangaspero F, Fauziah D, Kim JH, Liu L, Dandan W, Gao J, Lindeboom B, Blümcke I, Aronica E. Good interobserver and intraobserver agreement in the evaluation of the new ILAE classification of focal cortical dysplasias. Epilepsia. 2012 Aug;53(8):1341-1348. Pubmedid: 22642611.
  • Darvesh S, Leblanc AM, Macdonald IR, Reid GA, Bhan V, Macaulay RJ, Fisk JD. Butyrylcholinesterase activity in multiple sclerosis neuropathology. Chem Biol Interact. 2010 Sep;187(1-3):425-431. Pubmedid: 20122907.
  • Kiberd MB, Macaulay RJ, Christie SD. Skull base hemangiopericytoma: treatment options. Can J Neurol Sci. 2010 Jan;37(1):131-134. Pubmedid: 20169789.
  • Moeller JJ, Macaulay RJ, Valdmanis PN, Weston LE, Rouleau GA, Dupré N. Autosomal dominant sensory ataxia: a neuroaxonal dystrophy. Acta Neuropathol. 2008 Sep;116(3):331-336. Pubmedid: 18347805.
  • Kew AK, Macaulay R, Burrell S, Rubin S, Dow G, Couban S. Central nervous system graft-versus-host disease presenting with granulomatous encephalitis. Bone Marrow Transplant. 2007 Jul;40(2):183-184. Pubmedid: 17502894.
  • Al Dhanhani A, Macaulay R, Maloney B, Hanly JG. Meningeal involvement in Wegener's granulomatosis. J Rheum. 2006 Feb;33(2):364-367. Pubmedid: 16465672.
  • Cook DJ, Christie SD, Macaulay RJ, Rheaume DE, Holness RO. Fourth ventricular neurocytoma: case report and review of the literature. Can J Neurol Sci. 2004 Nov;31(4):558-564. Pubmedid: 15595267.
  • Wang W, Macaulay RJ. Cell-cycle gene expression in lovastatin-induced medulloblastoma apoptosis. Can J Neurol Sci. 2003 Nov;30(4):349-357. Pubmedid: 14672267.
  • Blevins G, Macaulay R, Harder S, Fladeland D, Yamashita T, Yazaki M, Hamidi Asl K, Benson MD, Donat JR. Oculoleptomeningeal amyloidosis in a large kindred with a new transthyretin variant Tyr69His. Neurology. 2003 May;60(10):1625-1630. Pubmedid: 12771253.
  • Perry A, Scheithauer BW, Macaulay RJ, Raffel C, Roth KA, Kros JM. Oligodendrogliomas with neurocytic differentiation. A report of 4 cases with diagnostic and histogenetic implications. J Neuropath Exp Neur. 2002 Nov;61(11):947-955. Pubmedid: 12430711.
  • Birdi S, Rajput AH, Fenton M, Donat JR, Rozdilsky B, Robinson C, Macaulay R, George D. Progressive supranuclear palsy diagnosis and confounding features: report on 16 autopsied cases. Movement Disord. 2002 Nov;17(6):1255-1264. Pubmedid: 12465065.
  • Rajput AH, Fenton ME, Birdi S, Macaulay R, George D, Rozdilsky B, Ang LC, Senthilselvan A, Hornykiewicz O. Clinical-pathological study of levodopa complications. Movement Disord. 2002 Mar;17(2):289-296. Pubmedid: 11921114.
  • Toth C, Voll C, Macaulay R. Primary CNS lymphoma as a cause of Korsakoff syndrome. Surg Neurol. 2002 Jan;57(1):41-45. Pubmedid: 11834275.
  • Kumar K, Macaulay RJ, Kelly M, Pirlot T. Absent p53 immunohistochemical staining in a pituitary carcinoma. Can J Neurol Sci. 2001 May;28(2):174-178. Pubmedid: 11383946.
  • Fourney DR, Tong KA, Macaulay RJ, Griebel RW. Spinal angiolipoma. Can J Neurol Sci. 2001 Feb;28(1):82-88. Pubmedid: 11252303.
  • Bruecks AK, Macaulay RJ, Tong KA, Goplen G. November 2000: 13 year old girl with back pain and leg weakness. Brain Pathol. 2001 Apr;11(2):263-264. Pubmedid: 11303802.
  • Wang W, Macaulay RJ. Mevalonate prevents lovastatin-induced apoptosis in medulloblastoma cell lines. Can J Neurol Sci. 1999 Nov;26(4):305-310. Pubmedid: 10563217.
  • Macaulay RJ, Wang W, Dimitroulakos J, Becker LE, Yeger H. Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro. J Neurooncol. 1999 Mar;42(1):1-11. Pubmedid: 10360474.
  • Wang W, Macaulay RJ. Apoptosis of medulloblastoma cells in vitro follows inhibition of farnesylation using manumycin A. Int J Cancer. 1999 Jul;82(3):430-434. Pubmedid: 10399961.
  • Lal S, Sharma RK, McGregor C, Macaulay RJ. Immunohistochemical localization of calmodulin-dependent cyclic phosphodiesterase in the human brain. Neurochem Res. 1999 Jan;24(1):43-49. Pubmedid: 9973236.
  • Macaulay RJ, Lowry NJ, Casey RE. Pathologic findings of multiple sulfatase deficiency reflect the pattern of enzyme deficiencies. Pediatr Neurol. 1998 Nov;19(5):372-376. Pubmedid: 9880143.
  • Rajput AH, Fenton Me, Birdi S, Macaulay R. Is levodopa toxic to human substantia nigra?. Movement Disord. 1997 Sep;12(5):634-638. Pubmedid: 9380042.
  • Macaulay RJ, Felix I, Jay V, Becker LE. Histological and ultrastructural analysis of six colloid cysts in children. Acta Neuropathol. 1997 Mar;93(3):271-276. Pubmedid: 9083559.
  • Macaulay RJ. Ruptured Rathke's cleft cyst: a possible cause of Tolosa-Hunt syndrome. Clin Neuropathol. 1997 Mar;16(2):98-102. Pubmedid: 9101112.
  • Lal S, Raju RV, Macaulay RJ, Sharma RK. Calmodulin-dependent cyclic nucleotide phosphodiesterase in human cerebral cortex and glioblastoma multiforme. Can J Neurol Sci. 1996 Nov;23(4):245-250. Pubmedid: 8951201.
  • Macaulay RJ, Jay V, Hoffman HJ, Becker LE. Increased mitotic activity as a negative prognostic indicator in pleomorphic xanthoastrocytoma. Case report. J Neurosurg. 1993 Nov;79(5):761-768. Pubmedid: 8410257.
  • Macaulay RJ, Sladky JT, Jay V. Muscle weakness in a 16-year-old girl. Pediatr Neurosurg. 1993 Mar;19(2):93-100. Pubmedid: 8443103.
  • Smith KA, Mackinnon SE, Macauley RJ, Mailis A. Glomus tumor originating in the radial nerve: a case report. J Hand Surg Am. 1992 Jul;17(4):665-667. Pubmedid: 1321179.
  • Pomeranz B, Macaulay RJ, Caudill MA, Kutz I, Adam D, Gordon D, Kilborn KM, Barger AC, Shannon DC, Cohen RJ. Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol. 1985 Jan;248(1 Pt 2):H151-H153. Pubmedid: 3970172.