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Kun Jiang, MD, PhD


Specialty: Pathology
Program: Anatomic Pathology

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Overview

Dr. Jiang completed a surgical pathology and gastrointestinal pathology fellowships at Emory University School of Medicine. Dr. Jiang’s clinical interest is in gastrointestinal pathology, including both neoplastic diseases and medical/ infectious processes and pancreatobiliary and liver pathology, including neoplasms and medical liver diseases. His research interests are to identify tumor markers during cancer initiation and progression in gastrointestinal, hepatic and pancreatobiliary neoplasms, so as to aid in the diagnoses and prognostication of these diseases.

Education & Training

Board Certification:

  • Pathology-Anatomic

Fellowship:

  • Emory University School of Medicine - Surgical Pathology
  • Emory University School of Medicine - Gastrointestinal Pathology

Residency:

  • Penn State Hershey Medical Center - Pathology

Medical School:

  • Beijing Medical University - MD, PhD
Participating Trials

If you believe you are eligible for one of these trials or studies, please call
1-888-MOFFITT (1-888-663-3488).

Publications

  • Permuth JB, Chen DT, Yoder SJ, Li J, Smith AT, Choi JW, Kim J, Balagurunathan Y, Jiang K, Coppola D, Centeno BA, Klapman J, Hodul P, Karreth FA, Trevino JG, Merchant N, Magliocco A, Malafa MP, Gillies R. Linc-ing Circulating Long Non-coding RNAs to the Diagnosis and Malignant Prediction of Intraductal Papillary Mucinous Neoplasms of the Pancreas. Sci Rep. 2017 Sep;7(1):10484. Pubmedid: 28874676. Pmcid: PMC5585319.
  • Jiang K, Tan E, Sayegh Z, Centeno B, Malafa M, Coppola D. Cancer Antigen 125 (CA125, MUC16) Protein Expression in the Diagnosis and Progression of Pancreatic Ductal Adenocarcinoma. Appl Immunohistochem Mol Morphol. 2017 Oct;25(9):620-623. Pubmedid: 27093451.
  • Almhanna K, Rosa M, Henderson-Jackson E, Jiang K, Shamekh R, Sayegh Z, Malafa MP, Coppola D. Her-2 Expression in Gastroesophageal Intestinal Metaplasia, Dysplasia, and Adenocarcinoma. Appl Immunohistochem Mol Morphol. 2016 Oct;24(9):633-638. Pubmedid: 26186253.
  • Jeong D, Jiang K, Anaya DA. Mucinous Cystic Neoplasm of the Liver Masquerading as an Echinococcal Cyst: Radiologic-pathologic Differential of Complex Cystic Liver Lesions. J Clin Imaging Sci. 2016 Mar;6:12. Pubmedid: 27195178. Pmcid: PMC4860451.
  • Black M, Hakam A, Harris C, Jiang K. Metastatic breast carcinoma uncovered in an otherwise unremarkable “random colon biopsy”. Human Pathology: Case Reports. 2016 Jun;4:23-31.
  • Kim R, Prithviraj GK, Shridhar R, Hoffe SE, Jiang K, Zhao X, Chen DT, Almhanna K, Strosberg J, Campos T, Shibata D. Phase I study of pre-operative continuous 5-FU and sorafenib with external radiation therapy in locally advanced rectal adenocarcinoma. Radiother Oncol. 2016 Feb;118(2):382-386. Pubmedid: 26861740.
  • Jiang K, Neill K, Cowden D, Klapman J, Eschrich S, Pimiento J, Malafa MP, Coppola D. Expression of CAS/CSE1L, the Cellular Apoptosis Susceptibility Protein, Correlates With Neoplastic Progression in Barrett's Esophagus. Appl Immunohistochem Mol Morphol. 2016 Dec. Pubmedid: 27941559. Pmcid: PMC5466515.
  • Permuth JB, Choi J, Balarunathan Y, Kim J, Chen DT, Chen L, Orcutt S, Doepker MP, Gage K, Zhang G, Latifi K, Hoffe S, Jiang K, Coppola D, Centeno BA, Magliocco A, Li Q, Trevino J, Merchant N, Gillies R, Malafa M, On Behalf Of The Florida Pancreas Collaborative . Combining radiomic features with a miRNA classifier may improve prediction of malignant pathology for pancreatic intraductal papillary mucinous neoplasms. Oncotarget. 2016 Dec;7(52):85785-85797. Pubmedid: 27589689. Pmcid: PMC5349874.
  • Jiang K, Lawson D, Cohen C, Siddiqui MT. Galectin-3 and PTEN expression in pancreatic ductal adenocarcinoma, pancreatic neuroendocrine neoplasms and gastrointestinal tumors on fine-needle aspiration cytology. Acta Cytol. 2014 Sep;58(3):281-287. Pubmedid: 24854395.
  • Shrewsberry AB, Osunkoya AO, Jiang K, Westby R, Canter D, Pattaras J, Turgeon N, Master VA, Ogan K. Renal cell carcinoma in patients with end-stage renal disease has favorable overall prognosis. Clin Transplant. 2014 Feb;28(2):211-216. Pubmedid: 24494735.
  • Jiang K, Rankin CR, Nava P, Sumagin R, Kamekura R, Stowell SR, Feng M, Parkos CA, Nusrat A. Galectin-3 regulates desmoglein-2 and intestinal epithelial intercellular adhesion. J Biol Chem. 2014 Apr;289(15):10510-10517. Pubmedid: 24567334. Pmcid: PMC4036172.
  • Chen KM, Guttenplan JB, Zhang SM, Aliaga C, Cooper TK, Sun YW, DelTondo J, Kosinska W, Sharma AK, Jiang K, Bruggeman R, Ahn K, Amin S, El-Bayoumy K. Mechanisms of oral carcinogenesis induced by dibenzo[a,l]pyrene: an environmental pollutant and a tobacco smoke constituent. Int J Cancer. 2013 Sep;133(6):1300-1309. Pubmedid: 23483552. Pmcid: PMC3707976.
  • Shi Z, Das S, Okwan-Duodu D, Esiashvili N, Flowers C, Chen Z, Wang X, Jiang K, Nastoupil LJ, Khan MK. Patterns of failure in advanced stage diffuse large B-cell lymphoma patients after complete response to R-CHOP immunochemotherapy and the emerging role of consolidative radiation therapy. Int J Radiat Oncol Biol Phys. 2013 Jul;86(3):569-577. Pubmedid: 23540349.
  • Guttenplan JB, Kosinska W, Zhao ZL, Chen KM, Aliaga C, DelTondo J, Cooper T, Sun YW, Zhang SM, Jiang K, Bruggeman R, Sharma AK, Amin S, Ahn K, El-Bayoumy K. Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer. Int J Cancer. 2012 Jun;130(12):2783-2790. Pubmedid: 21815141. Pmcid: PMC3596885.
  • Chappell DS, Patel NA, Jiang K, Li P, Watson JE, Byers DM, Cooper DR. Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells. Diabetologia. 2009 May;52(5):901-911. Pubmedid: 19252893. Pmcid: PMC2677811.
  • Jiang K, Patel NA, Watson JE, Apostolatos H, Kleiman E, Hanson O, Hagiwara M, Cooper DR. Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid. Endocrinology. 2009 May;150(5):2087-2097. Pubmedid: 19116344. Pmcid: PMC2671910.
  • Jiang K, Apostolatos AH, Ghansah T, Watson JE, Vickers T, Cooper DR, Epling-Burnette PK, Patel NA. Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdeltaVIII in NT2 cells. Biochemistry-Us. 2008 Jan;47(2):787-797. Pubmedid: 18092819.
  • Ghosh N, Patel N, Jiang K, Watson JE, Cheng J, Chalfant CE, Cooper DR. Ceramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ribonucleic acid splicing in L6 skeletal muscle cells. Endocrinology. 2007 Mar;148(3):1359-1366. Pubmedid: 17158207. Pmcid: PMC2664306.
  • Jiang K, Sun J, Cheng J, Djeu JY, Wei S, Sebti S. Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis. Mol Cell Biol. 2004 Jun;24(12):5565-5576. Pubmedid: 15169915. Pmcid: PMC419878.
  • Dan HC, Jiang K, Coppola D, Hamilton A, Nicosia SV, Sebti SM, Cheng JQ. Phosphatidylinositol-3-OH kinase/AKT and survivin pathways as critical targets for geranylgeranyltransferase I inhibitor-induced apoptosis. Oncogene. 2004 Jan;23(3):706-715. Pubmedid: 14737105.
  • Jiang K, Delarue FL, Sebti SM. EGFR, ErbB2 and Ras but not Src suppress RhoB expression while ectopic expression of RhoB antagonizes oncogene-mediated transformation. Oncogene. 2004 Feb;23(5):1136-1145. Pubmedid: 14647415.
  • Jiang K, Zhong B, Ritchey C, Gilvary DL, Hong-Geller E, Wei S, Djeu JY. Regulation of Akt-dependent cell survival by Syk and Rac. Blood. 2003 Jan;101(1):236-244. Pubmedid: 12393431.
  • Zhong B, Jiang K, Gilvary DL, Epling-Burnette PK, Ritchey C, Liu J, Jackson RJ, Hong-Geller E, Wei S. Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization toward ingested microbial pathogens. Blood. 2003 Apr;101(8):3240-3248. Pubmedid: 12511425.
  • Zhong B, Liu JH, Gilvary DL, Jiang K, Kasuga M, Ritchey CA, Trapani JA, Wei S. Functional role of phosphatidylinositol 3-kinase in direct tumor lysis by human natural killer cells. Immunobiology. 2002 Mar;205(1):74-94. Pubmedid: 11999346.
  • Jiang K, Zhong B, Gilvary DL, Corliss BC, Vivier E, Hong-Geller E, Wei S, Djeu JY. Syk regulation of phosphoinositide 3-kinase-dependent NK cell function. J Immunol. 2002 Apr;168(7):3155-3164. Pubmedid: 11907067.
  • Djeu J, Jiang K, Wei S. A view to a kill: signals triggering cytotoxicity. Clin Cancer Res. 2002;8(3):636-640. Pubmedid: 11895890.
  • Kim S, Loesch K, Wang X, Jiang J, Mei L, Cunnick J, Wu J, Frank S. A role for Grb2-associated binder-1 growth hormone signaling. Endocrinology. 2002;143(12):4856-4867. Pubmedid: 12446613.
  • Epling-Burnette PK, Zhong B, Bai F, Jiang K, Bailey RD, Garcia R, Jove R, Djeu JY, Loughran TP, Wei S. Cooperative regulation of Mcl-1 by Janus kinase/stat and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils. J Immunol. 2001 Jun;166(12):7486-7495. Pubmedid: 11390502.
  • Wei S, Liu JH, Epling-Burnette PK, Jiang K, Zhong B, Elkabani ME, Pearson EW, Djeu JY. IL-2 induces the association of IL-2Rbeta, lyn, and MAP kinase ERK-1 in human neutrophils. Immunobiology. 2000 Nov;202(4):363-382. Pubmedid: 11131153.
  • Jiang K, Zhong B, Gilvary D, Corliss B, Hong-Geller E, Wei S, Djeu J. Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells. Nat Immunol. 2000 Nov;1(5):419-425. Pubmedid: 11062502.
  • Jiang K, Coppola D, Crespo NC, Nicosia SV, Hamilton AD, Sebti SM, Cheng JQ. The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis. Mol Cell Biol. 2000 Jan;20(1):139-148. Pubmedid: 10594016. Pmcid: PMC85069.
  • Jiang K, Stephen FO, Jeong D, Pimiento JM. Pancreatic and Gastric Heterotopia with Associated Submucosal Lipoma Presenting as a 7-cm Obstructive Tumor of the Ileum: Resection with Double Balloon Enteroscopy. Case Rep Gastroenterol. 9(2):233-240. Pubmedid: 26269700. Pmcid: PMC4520188.