Jason Klapman, MD, FASGE

Cancer Focus:
Pancreatic Cancer

Dr. Jason Klapman is a gastroenterologist and Medical Director of Endoscopy in the Gastrointestinal Oncology Department at Moffitt Cancer Center.  He is an Senior Professor of oncology at the University of South Florida College of Medicine. Dr. Klapman received his medical degree from Finch University of Health Sciences/The Chicago Medical School.  He completed a residency in internal medicine at Rush University, Rush-Presbyterian-St. Luke’s Medical Center, where he was chief resident his last year. Dr. Klapman pursued additional training through a gastroenterology fellowship at the University of Chicago and an interventional endoscopy fellowship at the University of California at Irvine Medical Center. His clinical interests center around the diagnosis, staging and treatment of gastrointestinal malignancies with a focus on pancreatic cancer using advanced endoscopic procedures such as endoscopic ultrasound and ERCP. He is a nationally recognized gastroenterologist and researcher and has been invited faculty or course director for multiple educational and hands-on courses around the country focusing on education and training in gastroenterological procedures. Dr. Klapman performs clinical endoscopic research focusing on improving the diagnosis and treatment of a multitude of precancerous and cancerous gastrointestinal conditions. Dr. Klapman along with four of his colleagues from around the country have formed a research collaborative group called Mucin (mucingroup.com) whose purpose is to perform multicenter trials with this gastrointestinal endoscopy focus. This group has already generated multiple publications and research presentations at national meetings. Dr. Klapman’s research interests include early detection and screening of pancreatic cancer in high-risk individuals. He currently has an ongoing clinical trial enrolling patients at high-risk. He is also currently enrolling patients to compare two types of needles that place gold markers which are used to guide radiation in patients with pancreas cancer. Dr. Klapman is widely published, including peer-reviewed journals, book chapters and educational DVDs. 

 

Education & Training

Fellowship:

• University Chicago Hospital, Chicago, IL - Gastroenterology
• University of California at Irvine Medical Center, Orange, CA - Interventional Endoscopy

Residency:

• Rush Presbyterian St. Luke's Medical Center, Chicago, IL - Internal Medicine
• Rush Presbyterian St. Luke's Medical Center, Chicago, IL - Internal Medicine

Medical School:

• Finch University of Health Sciences/The Chicago Medical School - MD

• Paniccia A, Polanco PM, Boone BA, Wald AI, McGrath K, Brand RE, Khalid A, Kubiliun N, O'Broin-Lennon AM, Park WG, Klapman J, Tharian B, Inamdar S, Fasanella K, Nasr J, Chennat J, Das R, DeWitt J, Easler JJ, Bick B, Singh H, Fairley KJ, Sarkaria S, Sawas T, Skef W, Slivka A, Tavakkoli A, Thakkar S, Kim V, Vanderveldt HD, Richardson A, Wallace MB, Brahmbhatt B, Engels M, Gabbert C, Dugum M, El-Dika S, Bhat Y, Ramrakhiani S, Bakis G, Rolshud D, Millspaugh G, Tielleman T, Schmidt C, Mansour J, Marsh W, Ongchin M, Centeno B, Monaco SE, Ohori NP, Lajara S, Thompson ED, Hruban RH, Bell PD, Smith K, Permuth JB, Vandenbussche C, Ernst W, Grupillo M, Kaya C, Hogg M, He J, Wolfgang CL, Lee KK, Zeh H, Zureikat A, Nikiforova MN, Singhi AD. Prospective, Multi-Institutional, Real-Time Next-Generation Sequencing of Pancreatic Cyst Fluid Reveals Diverse Genomic Alterations That Improve the Clinical Management of Pancreatic Cysts. Gastroenterology. 2023 Jan.164(1):117-133.e7. Pubmedid: 36209796. Pmcid: PMC9844531.
• Naffouje SA, Allenson K, Hodul P, Malafa M, Pimiento JM, Anaya DA, Dam A, Klapman J, Fleming JB, Denbo JW. Prophylactic Perioperative Antibiotics in Open Pancreaticoduodenectomy: When Less Is More and When It Is Not. A National Surgical Quality Improvement Program Propensity-Matched Analysis. J Surg Res. 2022 Nov.279:722-732. Pubmedid: 35933790.
• Zakaria A, Al-Share B, Klapman JB, Dam A. The Role of Endoscopic Ultrasonography in the Diagnosis and Staging of Pancreatic Cancer. Cancers (Basel). 2022 Mar.14(6). Pubmedid: 35326524. Pmcid: PMC8946253.
• Dhaliwal A, Saghir SM, Mashiana HS, Braseth A, Dhindsa BS, Ramai D, Taunk P, Gomez-Esquivel R, Dam A, Klapman J, Adler DG. Endoscopic cryotherapy: Indications, techniques, and outcomes involving the gastrointestinal tract. World J Gastrointest Endosc. 2022 Jan.14(1):17-28. Pubmedid: 35116096. Pmcid: PMC8788170.
• Naffouje SA, Lauwers G, Klapman J, Dam A, Pena L, Friedman M, Sanchez J, Dessureault S, Felder S. Malignant colon polyps: predicting lymph node metastasis following endoscopic excision. Int J Colorectal Dis. 2022 Feb.37(2):393-402. Pubmedid: 35001147.
• Ragheb J, Mony S, Klapman J, Erim T, Reagan A, Butler R, Dong Y, Cruise M, Centeno BA, Bejarano P, Stevens T, Hayat U, Bhatt A. Impact of margin status on outcomes after endoscopic resection of well-differentiated duodenal neuroendocrine tumors. Gastrointest Endosc. 2021 Sep.94(3):580-588. Pubmedid: 33676923.
• Dhaliwal A, Dhindsa BS, Saghir SM, Ramai D, Chandan S, Mashiana H, Bhogal N, Sayles H, Bhat I, Singh S, Dam A, Taunk P, Esquivel RG, Klapman J, McDonough S, Adler DG. Choice of sedation in endoscopic retrograde cholangiopancreatography: is monitored anesthesia care as safe as general anesthesia? A systematic review and meta-analysis. Ann Gastroenterol. 2021 Nov.34(6):879-887. Pubmedid: 34815655. Pmcid: PMC8596211.
• Permuth JB, Dezsi KB, Vyas S, Ali KN, Basinski TL, Utuama OA, Denbo JW, Klapman J, Dam A, Carballido E, Kim DW, Pimiento JM, Powers BD, Otto AK, Choi JW, Chen DT, Teer JK, Beato F, Ward A, Cortizas EM, Whisner SY, Williams IE, Riner AN, Tardif K, Velanovich V, Karachristos A, Douglas WG, Legaspi A, Allan BJ, Meredith K, Molina-Vega MA, Bao P, St Julien J, Huguet KL, Green L, Odedina FT, Kumar NB, Simmons VN, George TJ, Vadaparampil ST, Hodul PJ, Arnoletti JP, Awad ZT, Bose D, Jiang K, Centeno BA, Gwede CK, Malafa M, Judge SM, Judge AR, Jeong D, Bloomston M, Merchant NB, Fleming JB, Trevino JG. The Florida Pancreas Collaborative Next-Generation Biobank: Infrastructure to Reduce Disparities and Improve Survival for a Diverse Cohort of Patients with Pancreatic Cancer. Cancers (Basel). 2021 Feb.13(4). Pubmedid: 33671939. Pmcid: PMC7919015.
• Morse B, Klapman J. Imaging of Pancreatic Tumors. Monogr Clin Cytol. 2020 Sep.26:21-33. Pubmedid: 32987388.
• Dam AN, Klapman J. A narrative review of Barrett's esophagus in 2020, molecular and clinical update. Ann Transl Med. 2020 Sep.8(17):1107. Pubmedid: 33145326. Pmcid: PMC7575938.
• Diaz LI, Mony S, Klapman J. Narrative review of the role of gastroenterologist in the diagnosis, treatment and palliation in gastric and gastroesophageal cancer. Ann Transl Med. 2020 Sep.8(17):1106. Pubmedid: 33145325. Pmcid: PMC7575985.
• Saller J, Al Diffalha S, Neill K, Bhaskar RA, Oliveri C, Boulware D, Levine H, Kalvaria I, Corbett FS, Khazanchi A, Klapman J, Coppola D. CDX-2 Expression in Esophageal Biopsies Without Goblet Cell Intestinal Metaplasia May Be Predictive of Barrett's Esophagus. Digest Dis Sci. 2020 Jul.65(7):1992-1998. Pubmedid: 31691172. Pmcid: PMC7771382.
• Bhutani MS, Klapman JB, Tuli R, El-Haddad G, Hoffe S, Wong FCL, Chasen B, Fogelman DR, Lo SK, Nissen NN, Hendifar AE, Varadhachary G, Katz MHG, Erwin WD, Koay EJ, Tamm EP, Singh BS, Mehta R, Wolff RA, Soman A, Cazacu IM, Herman JM. An open-label, single-arm pilot study of EUS-guided brachytherapy with phosphorus-32 microparticles in combination with gemcitabine +/- nab-paclitaxel in unresectable locally advanced pancreatic cancer (OncoPaC-1): Technical details and study protocol. Endosc Ultrasound. 2020 Jan.9(1):24-30. Pubmedid: 31670288. Pmcid: PMC7038730.
• Huynh T, Ali K, Vyas S, Dezsi K, Strickland D, Basinski T, Chen DT, Jiang K, Centeno B, Malafa M, Klapman JB, Hodul PJ, Jeong D, Permuth JB. Comparison of imaging modalities for measuring the diameter of intraductal papillary mucinous neoplasms of the pancreas. Pancreatology. 2020 Apr.20(3):448-453. Pubmedid: 32113936. Pmcid: PMC7346718.
• Gupta S, Provenzale D, Llor X, Halverson AL, Grady W, Chung DC, Haraldsdottir S, Markowitz AJ, Slavin TP, Hampel H, Ness RM, Weiss JM, Ahnen DJ, Chen LM, Cooper G, Early DS, Giardiello FM, Hall MJ, Hamilton SR, Kanth P, Klapman JB, Lazenby AJ, Lynch PM, Mayer RJ, Mikkelson J, Peter S, Regenbogen SE, Dwyer MA, Ogba N. NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 2.2019. J Natl Compr Canc Ne. 2019 Sep.17(9):1032-1041. Pubmedid: 31487681.
• McNamara GPJ, Ali KN, Vyas S, Huynh T, Nyland M, Almanza D, Laronga C, Klapman J, Permuth JB. Characteristics and Clinical Outcomes of Individuals at High Risk for Pancreatic Cancer: A Descriptive Analysis from a Comprehensive Cancer Center. Gastrointest Disord (Basel). 2019 Mar.1(1):106-119. Pubmedid: 32601617. Pmcid: PMC7324042.
• Wani S, Han S, Simon V, Hall M, Early D, Aagaard E, Abidi WM, Banerjee S, Baron TH, Bartel M, Bowman E, Brauer BC, Buscaglia JM, Carlin L, Chak A, Chatrath H, Choudhary A, Confer B, Coté GA, Das KK, DiMaio CJ, Dries AM, Edmundowicz SA, El Chafic AH, El Hajj I, Ellert S, Ferreira J, Gamboa A, Gan IS, Gangarosa L, Gannavarapu B, Gordon SR, Guda NM, Hammad HT, Harris C, Jalaj S, Jowell P, Kenshil S, Klapman J, Kochman ML, Komanduri S, Lang G, Lee LS, Loren DE, Lukens F, Mullady D, Muthusamy RV, Nett AS, Olyaee MS, Pakseresht K, Perera P, Pfau P, Piraka C, Poneros JM, Rastogi A, Razzak A, Riff B, Saligram S, Scheiman JM, Schuster I, Shah RJ, Sharma R, Spaete JP, Singh A, Sohail M, Sreenarasimhaiah J, Stevens T, Tabibian JH, Tzimas D, Uppal DS, Urayama S, Vitterbo D, Wang AY, Wassef W, Yachimski P, Zepeda-Gomez S, Zuchelli T, Keswani RN. Setting minimum standards for training in EUS and ERCP: results from a prospective multicenter study evaluating learning curves and competence among advanced endoscopy trainees. Gastrointest Endosc. 2019 Jun.89(6):1160-1168.e9. Pubmedid: 30738985. Pmcid: PMC6527477.
• Machicado JD, Obuch JC, Goodman KA, Schefter TE, Frakes J, Hoffe S, Latifi K, Simon VC, Santangelo T, Ezekwe E, Edmundowicz SA, Brauer BC, Shah RJ, Hammad HT, Wagh MS, Attwell A, Han S, Klapman J, Wani S. Endoscopic Ultrasound Placement of Preloaded Fiducial Markers Shortens Procedure Time Compared to Back-Loaded Markers. Clin Gastroenterol H. 2019 Dec.17(13):2749-2758.e2. Pubmedid: 31042578.
• Machicado JD, Klapman J, Wani S. Reply. Clin Gastroenterol H. 2019 Dec.17(13):2827. Pubmedid: 31220647.
• Jiang K, Neill K, Cowden D, Klapman J, Eschrich S, Pimiento J, Malafa MP, Coppola D. Expression of CAS/CSE1L, the Cellular Apoptosis Susceptibility Protein, Correlates With Neoplastic Progression in Barrett's Esophagus. Appl Immunohistochem Mol Morphol. 2018 Sep.26(8):552-556. Pubmedid: 27941559. Pmcid: PMC5466515.
• Wani S, Keswani RN, Han S, Aagaard E, Hall M, Simon V, Abidi WM, Banerjee S, Baron TH, Bartel M, Bowman E, Brauer BC, Buscaglia JM, Carlin L, Chak A, Chatrath H, Choudhary A, Confer B, Coté GA, Das KK, DiMaio CJ, Dries AM, Edmundowicz SA, El Chafic AH, El Hajj I, Ellert S, Ferreira J, Gamboa A, Gan IS, Gangarosa L, Gannavarapu B, Gordon SR, Guda NM, Hammad HT, Harris C, Jalaj S, Jowell P, Kenshil S, Klapman J, Kochman ML, Komanduri S, Lang G, Lee LS, Loren DE, Lukens F, Mullady D, Muthusamy RV, Nett AS, Olyaee MS, Pakseresht K, Perera P, Pfau P, Piraka C, Poneros JM, Rastogi A, Razzak A, Riff B, Saligram S, Scheiman JM, Schuster I, Shah RJ, Sharma R, Spaete JP, Singh A, Sohail M, Sreenarasimhaiah J, Stevens T, Tabibian JH, Tzimas D, Uppal D, Urayama S, Vitterbo D, Wang AY, Wassef W, Yachimski P, Zepeda-Gomez S, Zuchelli T, Early D. Competence in Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography, From Training Through Independent Practice. Gastroenterology. 2018 Nov.155(5):1483-1494.e7. Pubmedid: 30056094. Pmcid: PMC6504935.
• Gangi A, Malafa M, Klapman J. Endoscopic Ultrasound-Based Pancreatic Cancer Screening of High-Risk Individuals: A Prospective Observational Trial. Pancreas. 2018 May.47(5):586-591. Pubmedid: 29683970.
• Marshall C, Mounzer R, Hall M, Simon V, Centeno B, Dennis K, Dhillon J, Fan F, Khazai L, Klapman J, Komanduri S, Lin X, Lu D, Mehrotra S, Muthusamy VR, Nayar R, Paintal A, Rao J, Sams S, Shah J, Watson R, Rastogi A, Wani S. Suboptimal Agreement Among Cytopathologists in Diagnosis of Malignancy Based on Endoscopic Ultrasound Needle Aspirates of Solid Pancreatic Lesions: A Validation Study. Clin Gastroenterol H. 2018 Jul.16(7):1114-1122.e2. Pubmedid: 28911946.
• Provenzale D, Gupta S, Ahnen DJ, Markowitz AJ, Chung DC, Mayer RJ, Regenbogen SE, Blanco AM, Bray T, Cooper G, Early DS, Ford JM, Giardiello FM, Grady W, Hall MJ, Halverson AL, Hamilton SR, Hampel H, Klapman JB, Larson DW, Lazenby AJ, Llor X, Lynch PM, Mikkelson J, Ness RM, Slavin TP, Sugandha S, Weiss JM, Dwyer MA, Ogba N. NCCN Guidelines Insights: Colorectal Cancer Screening, Version 1.2018. J Natl Compr Canc Ne. 2018 Aug.16(8):939-949. Pubmedid: 30099370.
• Bledsoe JR, Wallace ZS, Deshpande V, Richter JR, Klapman J, Cowan A, Stone JH, Ferry JA. Atypical IgG4+ Plasmacytic Proliferations and Lymphomas: Characterization of 11 Cases. Am J Clin Pathol. 2017 Sep.148(3):215-235. Pubmedid: 28821195.
• Permuth JB, Chen DT, Yoder SJ, Li J, Smith AT, Choi JW, Kim J, Balagurunathan Y, Jiang K, Coppola D, Centeno BA, Klapman J, Hodul P, Karreth FA, Trevino JG, Merchant N, Magliocco A, Malafa MP, Gillies R. Linc-ing Circulating Long Non-coding RNAs to the Diagnosis and Malignant Prediction of Intraductal Papillary Mucinous Neoplasms of the Pancreas. Sci Rep. 2017 Sep.7(1):10484. Pubmedid: 28874676. Pmcid: PMC5585319.
• Gohil VB, Klapman JB. Endoscopic Palliation of Pancreatic Cancer. Curr Treat Options Gastroenterol. 2017 Sep.15(3):333-348. Pubmedid: 28795293.
• Oliver JA, Venkat P, Frakes JM, Klapman J, Harris C, Montilla-Soler J, Dhadham GC, Altazi BA, Zhang GG, Moros EG, Shridhar R, Hoffe SE, Latifi K. Fiducial markers coupled with 3D PET/CT offer more accurate radiation treatment delivery for locally advanced esophageal cancer. Endosc Int Open. 2017 Jun.5(6):E496-E504. Pubmedid: 28573183. Pmcid: PMC5451282.
• Lee A, Aditi A, Bhat YM, Binmoeller KF, Hamerski C, Sendino O, Kane S, Cello JP, Day LW, Mohamadnejad M, Muthusamy VR, Watson R, Klapman JB, Komanduri S, Wani S, Shah JN. Endoscopic ultrasound-guided biliary access versus precut papillotomy in patients with failed biliary cannulation: a retrospective study. Endoscopy. 2017 Feb.49(2):146-153. Pubmedid: 28107764.
• Luu C, Amaral M, Klapman J, Harris C, Almhanna K, Hoffe S, Frakes J, Pimiento JM, Fontaine JP. Endoscopic ultrasound staging for early esophageal cancer: Are we denying patients neoadjuvant chemo-radiation?. World J Gastroenterol. 2017 Dec.23(46):8193-8199. Pubmedid: 29290655. Pmcid: PMC5739925.
• Gupta S, Provenzale D, Regenbogen SE, Hampel H, Slavin TP, Hall MJ, Llor X, Chung DC, Ahnen DJ, Bray T, Cooper G, Early DS, Ford JM, Giardiello FM, Grady W, Halverson AL, Hamilton SR, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Markowitz AJ, Mayer RJ, Ness RM, Samadder NJ, Shike M, Sugandha S, Weiss JM, Dwyer MA, Ogba N. NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 3.2017. J Natl Compr Canc Ne. 2017 Dec.15(12):1465-1475. Pubmedid: 29223984.
• Glazer ES, Rashid OM, Klapman JB, Harris CL, Hodul PJ, Pimiento JM, Malafa MP. Endoscopic ultrasonography complements computed tomography in predicting portal or superior mesenteric vein resection in patients with borderline resectable pancreatic carcinoma. Pancreatology. 2017 Aug.17(1):130-134. Pubmedid: 28043760.
• Saligram S, Lim D, Pena L, Friedman M, Harris C, Klapman J. Safety and feasibility of esophageal self- expandable metal stent placement without the aid of fluoroscopy. Dis Esophagus. 2017 Aug.30(8):1-6. Pubmedid: 28575246.
• Watson RR, Klapman J, Komanduri S, Shah JN, Wani S, Muthusamy R. Wide disparities in attitudes and practices regarding Type II sphincter of Oddi dysfunction: a survey of expert U.S. endoscopists. Endosc Int Open. 2016 Sep.4(9):E941-E946. Pubmedid: 27652298. Pmcid: PMC5025319.
• Aadam AA, Wani S, Amick A, Shah JN, Bhat YM, Hamerski CM, Klapman JB, Muthusamy VR, Watson RR, Rademaker AW, Keswani RN, Keefer L, Das A, Komanduri S. A randomized controlled cross-over trial and cost analysis comparing endoscopic ultrasound fine needle aspiration and fine needle biopsy. Endosc Int Open. 2016 May.4(5):E497-E505. Pubmedid: 27227104. Pmcid: PMC4874800.
• Dhadham GC, Hoffe S, Harris CL, Klapman JB. Endoscopic ultrasound-guided fiducial marker placement for image-guided radiation therapy without fluoroscopy: safety and technical feasibility. Endosc Int Open. 2016 Mar.4(3):E378-E382. Pubmedid: 27004258. Pmcid: PMC4798935.
• Korrapati P, Ciolino J, Wani S, Shah J, Watson R, Muthusamy VR, Klapman J, Komanduri S. The efficacy of peroral cholangioscopy for difficult bile duct stones and indeterminate strictures: a systematic review and meta-analysis. Endosc Int Open. 2016 Mar.4(3):E263-E275. Pubmedid: 27004242. Pmcid: PMC4798839.
• Kucera S, Barthel J, Klapman J, Shridhar R, Hoffe S, Harris C, Almhanna K, Meredith K. Small caliber covered self-expanding metal stents in the management of malignant dysphagia. J Gastrointest Oncol. 2016 Jun.7(3):411-419. Pubmedid: 27284474. Pmcid: PMC4880758.
• Law R, Das A, Gregory D, Komanduri S, Muthusamy R, Rastogi A, Vargo J, Wallace MB, Raju GS, Mounzer R, Klapman J, Shah J, Watson R, Wilson R, Edmundowicz SA, Wani S. Endoscopic resection is cost-effective compared with laparoscopic resection in the management of complex colon polyps: an economic analysis. Gastrointest Endosc. 2016 Jun.83(6):1248-1257. Pubmedid: 26608129.
• Mahipal A, Klapman J, Vignesh S, Yang CS, Neuger A, Chen DT, Malafa MP. Pharmacokinetics and safety of vitamin E δ-tocotrienol after single and multiple doses in healthy subjects with measurement of vitamin E metabolites. Cancer Chemother Pharmacol. 2016 Jul.78(1):157-165. Pubmedid: 27278668. Pmcid: PMC4939900.
• Kim S, Hamerski C, Ghassemi K, Shah J, Bhat Y, Klapman J, Komanduri S, Keswani RN, Bidari K, Wani S, Watson RR, Muthusamy VR. The Clinical Utility of Evaluating the Luminal Upper Gastrointestinal Tract During Linear Endoscopic Ultrasonography. J Clin Gastroenterol. 2016 Aug.50(7):538-544. Pubmedid: 26501879.
• Provenzale D, Gupta S, Ahnen DJ, Bray T, Cannon JA, Cooper G, David DS, Early DS, Erwin D, Ford JM, Giardiello FM, Grady W, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Regenbogen SE, Samadder NJ, Shike M, Steinbach G, Weinberg D, Dwyer M, Darlow S. Genetic/Familial High-Risk Assessment: Colorectal Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Ne. 2016 Aug.14(8):1010-1030. Pubmedid: 27496117.
• Lin CL, Meredith K, Klapman J. Rate of Recurrent Luminal Esophageal Cancer in Asymptomatic Patients After Curative Treatment for Esophageal Cancer. J Clin Gastroenterol. 2015 Sep.49(8):e71-e75. Pubmedid: 25127115.
• Strom TJ, Klapman JB, Springett GM, Meredith KL, Hoffe SE, Choi J, Hodul P, Malafa MP, Shridhar R. Comparative long-term outcomes of upfront resected pancreatic cancer after preoperative biliary drainage. Surg Endosc. 2015 Nov.29(11):3273-3281. Pubmedid: 25631110. Pmcid: PMC4918460.
• Permuth-Wey J, Chen YA, Fisher K, McCarthy S, Qu X, Lloyd MC, Kasprzak A, Fournier M, Williams VL, Ghia KM, Yoder SJ, Hall L, Georgeades C, Olaoye F, Husain K, Springett GM, Chen DT, Yeatman T, Centeno BA, Klapman J, Coppola D, Malafa M. A genome-wide investigation of microRNA expression identifies biologically-meaningful microRNAs that distinguish between high-risk and low-risk intraductal papillary mucinous neoplasms of the pancreas. PLoS One. 2015 Jan.10(1):e0116869. Pubmedid: 25607660. Pmcid: PMC4301643.
• Ge PS, Hamerski CM, Watson RR, Komanduri S, Cinnor BB, Bidari K, Klapman JB, Lin CL, Shah JN, Wani S, Donahue TR, Muthusamy VR. Plastic biliary stent patency in patients with locally advanced pancreatic adenocarcinoma receiving downstaging chemotherapy. Gastrointest Endosc. 2015 Feb.81(2):360-366. Pubmedid: 25442083.
• Provenzale D, Jasperson K, Ahnen DJ, Aslanian H, Bray T, Cannon JA, David DS, Early DS, Erwin D, Ford JM, Giardiello FM, Gupta S, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Rao MS, Regenbogen SE, Shike M, Steinbach G, Weinberg D, Dwyer MA, Freedman-Cass DA, Darlow S. Colorectal Cancer Screening, Version 1.2015. J Natl Compr Canc Ne. 2015 Aug.13(8):959-968. Pubmedid: 26285241.
• You Y, Shao H, Bui K, Bui M, Klapman J, Cui Q, Coppola D. Epstein-Barr virus positive inflammatory pseudotumor of the liver: report of a challenging case and review of the literature. Ann Clin Lab Sci. 2014 Nov.44(4):489-498. Pubmedid: 25361938.
• Fernandez DC, Hoffe SE, Barthel JS, Vignesh S, Klapman JB, Harris C, Almhanna K, Biagioli MC, Meredith KL, Feygelman V, Rao NG, Shridhar R. Stability of endoscopic ultrasound-guided fiducial marker placement for esophageal cancer target delineation and image-guided radiation therapy. Pract Radiat Oncol. 2014 Mar.3(1):32-39. Pubmedid: 24674261.
• Brugge WR, De Witt J, Klapman JB, Ashfaq R, Shidham V, Chhieng D, Kwon R, Baloch Z, Zarka M, Staerkel G. Techniques for cytologic sampling of pancreatic and bile duct lesions: The Papanicolaou Society of Cytopathology Guidelines. Cytojournal. 2014 Jun.11(Suppl 1):2. Pubmedid: 25191516. Pmcid: PMC4153336.
• Harris CL, Toloza EM, Klapman JB, Vignesh S, Rodriguez K, Kaszuba FJ. Minimally invasive mediastinal staging of non-small-cell lung cancer: emphasis on ultrasonography-guided fine-needle aspiration. Cancer Control. 2014 Jan.21(1):15-20. Pubmedid: 24357737.
• Brugge W, Dewitt J, Klapman JB, Ashfaq R, Shidham V, Chhieng D, Kwon R, Baloch Z, Zarka M, Staerkel G. Techniques for cytologic sampling of pancreatic and bile duct lesions. Diagn Cytopathol. 2014 Apr.42(4):333-337. Pubmedid: 24554498.
• Herman JM, Wild AT, Wang H, Tran PT, Chang KJ, Taylor GE, Donehower RC, Pawlik TM, Ziegler MA, Cai H, Savage DT, Canto MI, Klapman J, Reid T, Shah RJ, Hoffe SE, Rosemurgy A, Wolfgang CL, Laheru DA. Randomized phase III multi-institutional study of TNFerade biologic with fluorouracil and radiotherapy for locally advanced pancreatic cancer: final results. J Clin Oncol. 2013 Mar.31(7):886-894. Pubmedid: 23341531. Pmcid: PMC4820756.
• Wong J, Weber J, A Centeno B, Vignesh S, Harris CL, Klapman JB, Hodul P. High-grade dysplasia and adenocarcinoma are frequent in side-branch intraductal papillary mucinous neoplasm measuring less than 3 cm on endoscopic ultrasound. J Gastrointest Surg. 2013 Jan.17(1):78-84. Pubmedid: 22948841.
• Burt RW, Cannon JA, David DS, Early DS, Ford JM, Giardiello FM, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Jasperson K, Klapman JB, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Provenzale D, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Dwyer M, Freedman-Cass D. Colorectal cancer screening. J Natl Compr Canc Ne. 2013 Dec.11(12):1538-1575. Pubmedid: 24335688.
• Kucera S, Centeno BA, Springett G, Malafa MP, Chen YA, Weber J, Klapman J. Cyst fluid carcinoembryonic antigen level is not predictive of invasive cancer in patients with intraductal papillary mucinous neoplasm of the pancreas. JOP. 2012 Jul.13(4):409-413. Pubmedid: 22797397.
• Lin JL, Barthel JS, Keshishian J, Eikman EA, Klapman JB. Negative predictive value of positron emission tomography/computed tomography in patients with a clinical suspicion of pancreatic cancer. Pancreas. 2011 Jul.40(5):653-656. Pubmedid: 21602734.
• Patel M, Hoffe S, Malafa M, Hodul P, Klapman J, Centeno B, Kim J, Helm J, Valone T, Springett G. Neoadjuvant GTX chemotherapy and IMRT-based chemoradiation for borderline resectable pancreatic cancer. J Surg Oncol. 2011 Aug.104(2):155-161. Pubmedid: 21520097. Pmcid: PMC3347705.
• Klapman J, Malafa M. Early detection of pancreatic cancer: why, who, and how to screen. Cancer Control. 2008 Oct.15(4):280-287. Pubmedid: 18813195.
• Nair R, Barthel J, Centeno B, Choi J, Klapman J, Malafa M. Interdisciplinary management of an intraductal papillary mucinous neoplasm of the pancreas. Cancer Control. 2008 Oct.15(4):322-333. Pubmedid: 18813200.
• Barthel JS, Kelley ST, Klapman JB. Management of persistent gastroesophageal anastomotic strictures with removable self-expandable polyester silicon-covered (Polyflex) stents: an alternative to serial dilation. Gastrointest Endosc. 2008 Mar.67(3):546-552. Pubmedid: 18294520.
• Jensen EH, Klapman JB, Kelley ST. Angiolipoma of the esophagus: a rare clinical dilemma. Dis Esophagus. 2006.19(3):203-207. Pubmedid: 16723000.
• Klapman JB, Chang KJ. Endoscopic ultrasound-guided fine-needle injection. Gastrointest Endosc Clin N Am. 2005 Jan.15(1):169-77, x. Pubmedid: 15555959.
• Klapman JB, Chang KJ, Lee JG, Nguyen P. Negative predictive value of endoscopic ultrasound in a large series of patients with a clinical suspicion of pancreatic cancer. Am J Gastroenterol. 2005 Dec.100(12):2658-2661. Pubmedid: 16393216.
• Klapman JB, Ene-Stroescu D, Becker MA, Hanauer SB. A lupus-like syndrome associated with infliximab therapy. Inflamm Bowel Dis. 2003 May.9(3):176-178. Pubmedid: 12792223.