Dr. Peguero received his MD from Ponce School of Medicine, Puerto Rico. He completed a neurology residency at the University of South Florida, Morsani College of Medicine. After completing his residency, Dr. Peguero completed a fellowship in epilepsy and EEG at Vanderbilt University School of Medicine. After his fellowship, Dr. Peguero was employed at The Watson Clinic, Department of Neurology, Lakeland, Florida, where he also served as Chief of Service of Neurology at Lakeland Regional Medical Center. Dr. Peguero was an Assistant Professor at Ponce School of Medicine, and most recently, he has worked in private practice.
Dr. Peguero’s clinical interest is in General Neurology, Epilepsy and Clinical Neurophysiology. He will help expand our diagnostic and therapeutic strategies in Onco-Neurology using advanced electrophysiologic techniques in EMG and EEG. This capability is especially important in the Neurologic complications of novel therapies such as check point inhibitors and CAR-T therapies.
Education & Training
Vanderbilt University School of Medicine - Epilepsy and EEG
Vogelbaum MA, Kroll D, Etame A, Tran N, Liu J, Ford A, Sparr E, Kim Y, Forsyth P, Sahebjam S, Mokhtari S, Peguero E, Macaulay R. A Prospective Validation Study of the First 3D Digital Exoscope for Visualization of 5-ALA-Induced Fluorescence in High-Grade Gliomas. World Neurosurg. 2021 May.149:e498-e503. Pubmedid: 33561551.
Akgul Babacan N, Peguero E, Forsyth P, Eroglu Z. BRAF Inhibitor Therapy-Related Encephalitis in a Patient with Metastatic Melanoma. Oncologist. 2021 Jul. Pubmedid: 34227206.
Sahebjam S, Forsyth PA, Tran ND, Arrington JA, Macaulay R, Etame AB, Walko CM, Boyle T, Peguero EN, Jaglal M, Mokhtari S, Enderling H, Raghunand N, Gatewood T, Long W, Dzierzeski JL, Evernden B, Robinson T, Wicklund MC, Kim S, Thompson ZJ, Chen DT, Chinnaiyan P, Yu HM. Hypofractionated stereotactic re-irradiation with pembrolizumab and bevacizumab in patients with recurrent high-grade gliomas: results from a phase I study. Neurooncol. 2021 Apr.23(4):677-686. Pubmedid: 33173935. Pmcid: PMC8041351.
Piña Y, Fusco MJ, Macaulay RJ, Walko CM, Peguero E, Evernden BR, Smalley KS, Forsyth P. Using personalized medicine in gliomas: a genomic approach to diagnosis and overcoming treatment resistance in a case with pleomorphic xanthoastrocytoma. J Neurol. 2020 Mar.267(3):783-790. Pubmedid: 31748891. Pmcid: PMC7035305.
Kasischke KA, Peguero EN, Sriaroon C, Moreo N, Ren Z, Mokin MV, Rose DZ. Immediate Transfer for Clot Extraction in a Young Woman With Leukemia and Asparaginase-Associated Acute Cerebral Vein Thrombosis. Neurohospitalist. 2020 Jan.10(1):58-63. Pubmedid: 31839868. Pmcid: PMC6900648.
Jaffer M, Chung M, Sharda E, Ramsakal A, Peguero E, Verma N, Mokhtari S. Immunotherapy Induced Myasthenic-Like Syndrome in a Metastatic Melanoma Patient With Amyotrophic Lateral Sclerosis. Clin Med Insights Oncol. 2020 Dec.14. Pubmedid: 33447124. Pmcid: PMC7780164.
Keerty D, Kessler R, Koverzhenko V, Peguero E. Dyskinesia during concomitant usage of phenytoin and capecitabine. Postgrad Med J. 2020 Aug. Pubmedid: 32769104.
Chung M, Jaffer M, Verma N, Mokhtari S, Ramsakal A, Peguero E. Immune checkpoint inhibitor induced anti-glutamic acid decarboxylase 65 (Anti-GAD 65) limbic encephalitis responsive to intravenous immunoglobulin and plasma exchange. J Neurol. 2020 Apr.267(4):1023-1025. Pubmedid: 31832829.
Maller B, Peguero E, Tanvetyanon T. Ipilimumab/Nivolumab-related Opsoclonus-Myoclonus-Ataxia Syndrome Variant in a Patient with Malignant Pleural Mesothelioma. J Immunother. 2018 Nov.41(9):411-412. Pubmedid: 29742520.
Peguero E, Abou-Khalil B, Fakhoury T, Mathews G. Self-injury and incontinence in psychogenic seizures. Epilepsia. 1995 Jun.36(6):586-591. Pubmedid: 7555972.
Fakhoury T, Abou-Khalil B, Peguero E. Differentiating clinical features of right and left temporal lobe seizures. Epilepsia. 1994 Sep.35(5):1038-1044. Pubmedid: 7925149.
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