Skip to nav Skip to content

Dr. Robert Wenham studies cancer scans

Metastatic uterine (endometrial) cancer is a type of cancer that originated in the lining of the uterus (endometrium) and has spread to distant areas of the body. In general, uterine cancer can metastasize to the rectum or bladder. Other areas where it may spread include the vagina, ovaries and fallopian tubes. This form of cancer is typically slow-growing and often detected before it has spread to more distant areas of the body.

What are the symptoms of metastatic uterine cancer?

In its early stages, uterine cancer may cause very mild symptoms or no symptoms at all. As it progresses, symptoms become more likely to occur. You may notice vaginal bleeding either between menstrual periods or after menopause. Other symptoms include:

  • Frequent or painful urination
  • Pain during sexual intercourse
  • Unexpected weight loss
  • Persistent cramping in the pelvic area
  • Anemia

A physician can run the necessary diagnostic tests to determine if metastatic uterine cancer is the cause of your symptoms. If you are experiencing these symptoms, it is important not to panic, as many other, milder conditions can cause similar symptoms.

How is metastatic uterine cancer treated?

Treatment of metastatic uterine cancer requires the expertise of a multispecialty team that has a high level of experience with this malignancy – such as the specialists at Moffitt Cancer Center. Our team collaborates as a tumor board, ensuring every Moffitt patient with metastatic uterine cancer receives a treatment plan tailored to her unique needs. Additionally, Moffitt is at the forefront of cancer research and offers a number of clinical trials that patients may be eligible to participate in. These clinical trials provide access to the latest and most advanced treatments before they have been made widely available. Virtual visits appointments are also available.

Medically reviewed by Jing-Yi Chern, MD, ScM, gynecologic oncologist 

If you would like to learn more about receiving diagnostic or treatment services at Moffitt for metastatic uterine cancer, fill out a new patient registration form or call 1-888-663-3488. We welcome patients with or without a referral.