COVID-19 Vaccine

Man receiving COVID vaccine

UPDATE: The FDA and CDC have authorized a Pfizer-BioNTech COVID-19 booster dose, and Moffitt Cancer Center will offer the shot to eligible patients starting Tuesday, Sept. 28. Moffitt is also planning to offer Moderna boosters as soon as they are approved by the FDA and CDC.

Eligibility
Cancer patients 18 and older who received the Pfizer-BioNTech vaccine at least six months ago are eligible for the booster. Please note, third doses are still available for patients who meet the immunocompromised status. Please see below.

Scheduling Your Appointment
Call 813-745-8000 to schedule your booster shot. You may schedule your appointment when you are within two weeks of the six-month mark of receiving your second dose. Appointments are available at Moffitt Cancer Center on USF’s campus and the Richard M. Schulze Family Foundation Outpatient Center at the McKinley campus.

Additional Criteria

  • Please bring your vaccine card to be signed. You will also receive a printed confirmation of your booster dose.
  • If you were not previously vaccinated at Moffitt, you must provide documentation that you received the Pfizer-BioNTech vaccine. Mixing brands is not allowed. If you do not bring proof, we will not be able to administer the vaccine.

Vaccination Clinics

8:30 a.m.-4 p.m. Monday-Friday, Stabile Research Building atrium
7:30 a.m.-3 p.m. Saturday, Moffitt Clinic Building Blood Draw

8:30 a.m.-4 p.m. Monday-Friday, *Room 2201 on the second floor (formerly Lori’s Gifts) next to Rehab Services & PAT
*Please check in first with Central Registration on the first floor 

Third Dose of Pfizer and Moderna Vaccine Underway
Moffitt continues to offer a third dose of the mRNA COVID-19 vaccines — Pfizer-BioNTech and Moderna — for immunocompromised patients and staff.

A third dose of the Pfizer or Moderna vaccine is recommended for people who are moderately or severely immunocompromised. This includes:

  • Patients who are currently receiving medications to actively treat a cancer or were given those treatments in the past 12 months.
  • Patients currently undergoing radiation therapy or who had undergone radiation treatments in the past 12 months.
  • Patients with severe primary immunodeficiency syndromes such as DiGeorge and Wiskott-Aldrich.
  • Patients who are actively being treated with high dose corticosteroids equivalent to at least 20 milligrams of prednisone daily.
  • Patients who are actively being treated with Tumor Necrosis Factor (TNF) blockers used for autoimmune conditions such as rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, Crohn’s disease and others. These drugs include Humira, Cimzia, Enbrel, Simponi, Remicade and their biosimilars.
  • Patients who have undergone solid organ transplants and who are on immunosuppressive medications.
  • Blood and marrow transplant patients and those who have undergone CAR T-cell therapy should discuss with their treating physician whether the timing is right for them to receive a third dose.
  • Patients being treated for malignant hematology conditions should also discuss with their treating physician whether the timing is right for a third dose.

Additional Criteria for Third Dose

  • You must bring proof of receiving the Pfizer or Moderna vaccine to be eligible for a third dose of the same kind.
  • For the Johnson & Johnson vaccine: The FDA and CDC say a booster will likely be needed eight months after vaccination. If you received this vaccine, be prepared to return to your original vaccination site or another community site.

Scheduling Your Third Dose
To check your eligibility, please send a message to your health care team through the MyMoffitt Patient Portal or call 813-745-8000 to have a message relayed to your provider. Please bring your vaccine card to be signed. You will also receive a printed confirmation of your third dose.

Scheduling Your First Dose
The FDA has granted full approval of the Comirnaty Pfizer-BioNTech two-dose vaccine for people 16 and older. If you are a Moffitt patient and would like to schedule your first dose of the vaccine, please call 813-745-8000.


The COVID-19 vaccines are among the most effective and safest vaccines ever developed. The FDA has granted full approval of the Comirnaty Pfizer-BioNTech two-dose vaccine for people 16 and older. Both the Pfizer and Moderna vaccines are shown to be approximately 95% effective. It is safe for most cancer patients to receive the vaccine. However, for some patients in active treatment that causes immunosuppression, the vaccine may not be effective.

It is considered safe to receive the flu vaccine around the same time as a COVID-19 third dose or booster dose. Talk to your physician if you have questions.

Moffitt is conducting research into the effectiveness and durability of the vaccine in cancer patients. If you have questions about the vaccine and how it fits within your treatment plan, please contact your care team through the message center within the MyMoffitt Patient Portal. Your care team will respond to your message after reviewing your medical history. For portal assistance, please call 813-745-8000.

It is also important not to delay any treatment for cancer in order to receive the COVID-19 vaccine.

If you are a cancer survivor, it should be safe for you to receive the vaccine. If you have concerns, talk to your oncologist or primary care physician.