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Martine Extermann, MD, PhD

Program Leader, Senior Adult Oncology Program

Specialty: Medical Oncology
Program: Senior Adult Oncology

Call 1-888-MOFFITT

or call 1-888-MOFFITT


Cancer Types Treated: Breast Cancer, Colon Cancer, Colorectal Cancer, Esophageal Cancer, Gallbladder Cancer, Hodgkin Lymphoma, Leukemia, Liver Cancer, Lung Cancer, Mesothelioma, Myelodysplastic Syndromes (MDS), Non-Hodgkin Lymphoma, Pancreatic Cancer, Rectal Cancer, Small Intestine Cancer, Stomach (Gastric) Cancer

Dr. Martine Extermann is Professor of Oncology and Medicine at the University of South Florida. She is Program Leader in the Senior Adult Oncology Program at Moffitt Cancer Center. She earned her medical diploma and her medical PhD at the University of Geneva, Switzerland. She has a Swiss Board Certification in Internal Medicine, specialty Oncology-Hematology. She also holds ABIM certifications in Internal Medicine and Medical Oncology. She has worked at Moffitt since 1994 and has been a faculty member since 1997. Her clinical activity and research focus on cancer in older patients.  Her main areas of investigation are how cancer behavior and its treatment are influenced by the general health of the patient and other diseases they have, how to predict and optimize treatment tolerance, and how to include the benefits of a comprehensive geriatric assessment (CGA) for cancer patients. Dr Extermann’s research has received numerous grants from the National Institutes of Health and foundations such as e.g. the American Cancer Society and the Kay Yow Cancer Fund/V Foundation. She has served as President of the International Society of Geriatric Oncology (SIOG), and is also a founding board member. She is the chair of the SIOG CGA task force. She serves on several American Society of Clinical Oncology (ASCO) Committees and the Editorial Board of scientific journals. Dr. Extermann has been presented with the following awards: The B.J. Kennedy Award for Scientific Excellence in Geriatric Oncology from ASCO in 2009; The Paul Calabresi Award from SIOG in 2014; A Lifetime Achievement Award in Geriatric Oncology by the German Society of Geriatrics and German Society of Hematology/Oncology in 2015.

Education & Training

Board Certification:

  • Medical Oncology
  • Internal Medicine


  • University Hospital (CHUV) Lausanne - Hematology
  • University of South Florida College of Medicine - Medical Oncology/Senior Adult Oncology


  • Hospital de la Chaux-de-Fonds - Surgery
  • Hospital Cantonal de Fribourg and University Hospital, Geneva - Internal Medicine

Medical School:

  • University of Geneva, Switzerland - MD
Participating Trials

Determinants of Age-Related Treatment Effectiveness in Ovarian Cancer: Prospective Study of Pharmacokinetics Patterns and Underlying Biology.
Intervention: Paraplatin (carboplatin); Taxol (paclitaxel); carboplatin; paclitaxel

A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients who have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy

A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy
Intervention: Not Applicable

Phase I Study of Pre-operative Capecitabine and Lenvatinib with External Radiation Therapy in Locally Advanced Rectal Adenocarcinoma
Intervention: E7080 (Lenvatinib); Lenvatinib (Lenvima); Xeloda (capecitabine); capecitabine

A Phase 1, First-in-Human, Open Label, Dose Escalation Study of MGD007, A Humanized gpA33 x CD3 Dual-Affinity Re-Targeting (DART) Protein in Patients with Relapsed/Refractory Metastatic Colorectal Carcinoma
Intervention: MGD007

An Open Label, Single Arm Pilot Study of OncoSil, Administered to Subjects with Unresectable Locally Advanced Pancreatic Adenocarcinoma, Given in Combination with Gemcitabine or Gemcitabine+Nab-Paclitaxel Chemotherapies
Intervention: Gemzar (gemcitabine); Nab-paclitaxel (Abraxane); OncoSil Microparticles / Diluent; gemcitabine

Multicenter, Open-label, Phase 1, Dose-escalation,Cohort-expansion, First-in-Human Study of KHK2455 Administered as Monotherapy and in Combination with Mogamulizumab (KW-0761) in Adult Subjects with Locally Advanced or Metastatic Solid Tumors
Intervention: KHK2455; KW-0761 (Mogamulizumab); Mogamulizumab

A Phase I/II Study of Pembrolizumab in Combination with Ibrutinib for Advanced, Refractory Colorectal Cancers
Intervention: 748645 (Ibrutinib); Ibrutinib (Imbruvica); PCI-32765 (Ibrutinib); Pembrolizumab (Keytruda)

A Randomized, Open-Label, Phase 3 Study of Abemaciclib Combined with Standard Adjuvant Endocrine Therapy versus Standard Adjuvant Endocrine Therapy Alone in Patients with High Risk, Node Positive, Early Stage,Hormone Receptor Positive, Human Epidermal Receptor 2 Negative, Breast Cancer
Intervention: Abemaciclib; LY2835219 (Abemaciclib)

A Phase II Investigator Sponsored Study of Nivolumab in Patients with Advanced Refractory Biliary Tract Cancers
Intervention: BMS-936558 (Nivolumab); Nivolumab

An Open-Label, Single-Arm Pilot Study Evaluating The Antitumor Activity And Safety Of Niraparib As Neoadjuvant Treatment In Localized, Her2-Negative, Brca-Mutant Breast Cancer Patients
Intervention: Niraparib

A Phase 1b Multi-cohort Study of the Combination of Pembrolizumab (MK-3475) plus Binimetinib alone or the Combination of Pembrolizumab plus Chemotherapy with or without Binimetinib in Participants with Metastatic Colorectal Cancer (KEYNOTE-651)
Intervention: Binimetinib; FOLFIRI; FOLFOX; Pembrolizumab (Keytruda)

Single Arm, Open Label Phase 1b/2 Study of SGN-LIV1A in Combination with Pembrolizumab for First-Line Treatment of Patients with Unresectable Locally-Advanced or Metastatic Triple-Negative Breast Cancer
Intervention: Pembrolizumab (Keytruda); SGN-LIV1A

If you believe you are eligible for one of these trials or studies, please call
813-745-6100 or toll-free 1-800-679-0775.


  • Extermann M. Celebrating a giant in geriatric oncology. Geriatr Oncol. 2018 May;9(3):181-182. Pubmedid: 29545084.
  • Dougoud-Chauvin V, Lee JJ, Santos E, Williams VL, Battisti NML, Ghia K, Sehovic M, Croft C, Kim J, Balducci L, Kish JA, Extermann M. Using Big Data in oncology to prospectively impact clinical patient care: A proof of concept study. Geriatr Oncol. 2018 Apr. Pubmedid: 29678669.
  • Battisti NML, Sehovic M, Extermann M. Assessment of the External Validity of the National Comprehensive Cancer Network and European Society for Medical Oncology Guidelines for Non-Small-Cell Lung Cancer in a Population of Patients Aged 80 Years and Older. Clin Lung Cancer. 2017 Sep;18(5):460-471. Pubmedid: 28416124.
  • Lee JJ, Kim J, Sehovic M, Chen L, Extermann M. Using heat maps to assess the multidimensional association of comorbidities with survival in older cancer patients treated with chemotherapy. Geriatr Oncol. 2017 Sep;8(5):336-342. Pubmedid: 28739160. Pmcid: PMC5581700.
  • Extermann M, Leeuwenburgh C, Samiian L, Sehovic M, Xu J, Cubitt C, Jacobsen PB, Pahor M, Grobmyer SR, Manini TM. Impact of chemotherapy on medium-term physical function and activity of older breast cancer survivors, and associated biomarkers. Geriatr Oncol. 2017 Jan;8(1):69-75. Pubmedid: 27743848. Pmcid: PMC5299045.
  • Extermann M. Cancer in the Elderly: Moving the Needle Toward Evidence-Based Personalized Oncology. Int J Radiat Oncol Biol Phys. 2017 07;98(4):718-720. Pubmedid: 28602406.
  • VanderWalde N, Jagsi R, Dotan E, Baumgartner J, Browner IS, Burhenn P, Cohen HJ, Edil BH, Edwards B, Extermann M, Ganti AK, Gross C, Hubbard J, Keating NL, Korc-Grodzicki B, McKoy JM, Medeiros BC, Mrozek E, O'Connor T, Rugo HS, Rupper RW, Shepard D, Silliman RA, Stirewalt DL, Tew WP, Walter LC, Wildes T, Bergman MA, Sundar H, Hurria A. NCCN Guidelines Insights: Older Adult Oncology, Version 2.2016. J Natl Compr Canc Ne. 2016 Nov;14(11):1357-1370. Pubmedid: 27799507.
  • Mohile SG, Hurria A, Cohen HJ, Rowland JH, Leach CR, Arora NK, Canin B, Muss HB, Magnuson A, Flannery M, Lowenstein L, Allore HG, Mustian KM, Demark-Wahnefried W, Extermann M, Ferrell B, Inouye SK, Studenski SA, Dale W. Improving the quality of survivorship for older adults with cancer. Cancer. 2016 Aug;122(16):2459-2568. Pubmedid: 27172129. Pmcid: PMC4974133.
  • Magnuson A, Allore H, Cohen HJ, Mohile SG, Williams GR, Chapman A, Extermann M, Olin RL, Targia V, Mackenzie A, Holmes HM, Hurria A. Geriatric assessment with management in cancer care: Current evidence and potential mechanisms for future research. Geriatr Oncol. 2016 07;7(4):242-248. Pubmedid: 27197915. Pmcid: PMC4969156.
  • Williams GR, Mackenzie A, Magnuson A, Olin R, Chapman A, Mohile S, Allore H, Somerfield MR, Targia V, Extermann M, Cohen HJ, Hurria A, Holmes H. Comorbidity in older adults with cancer. Geriatr Oncol. 2016 07;7(4):249-257. Pubmedid: 26725537. Pmcid: PMC4917479.
  • Extermann M, Reich RR, Sehovic M. Chemotoxicity recurrence in older patients: Risk factors and effectiveness of preventive strategies-a prospective study. Cancer. 2015 Sep;121(17):2984-2992. Pubmedid: 26033177. Pmcid: PMC4545718.
  • Dilling TJ, Extermann M, Kim J, Thompson LM, Yue B, Stevens CW, Antonia S, Gray J, Williams C, Haura E, Pinder-Schenck M, Tanvetyanon T, Kim S, Chiappori A. Phase 2 study of concurrent cetuximab plus definitive thoracic radiation therapy followed by consolidation docetaxel plus cetuximab in poor prognosis or elderly patients with locally advanced non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2014 Nov;90(4):828-833. Pubmedid: 25216856.
  • Kiderlen M, de Glas NA, Bastiaannet E, van de Water W, de Craen AJ, Guicherit OR, Merkus JW, Extermann M, van de Velde CJ, Liefers GJ. Impact of comorbidity on outcome of older breast cancer patients: a FOCUS cohort study. Breast Cancer Res Treat. 2014 May;145(1):185-192. Pubmedid: 24676624.
  • van de Water W, Bastiaannet E, Egan KM, de Craen AJ, Westendorp RG, Balducci L, van de Velde CJ, Liefers GJ, Extermann M. Management of primary metastatic breast cancer in elderly patients--an international comparison of oncogeriatric versus standard care. Geriatr Oncol. 2014 Jul;5(3):252-259. Pubmedid: 24661770. Pmcid: PMC4617765.
  • Popa MA, Wallace KJ, Brunello A, Extermann M, Balducci L. Potential drug interactions and chemotoxicity in older patients with cancer receiving chemotherapy. Geriatr Oncol. 2014 Jul;5(3):307-314. Pubmedid: 24821377. Pmcid: PMC4154059.
  • Liu JJ, Druta M, Shibata D, Coppola D, Boler I, Elahi A, Reich RR, Siegel E, Extermann M. Metabolic syndrome and colorectal cancer: is hyperinsulinemia/insulin receptor-mediated angiogenesis a critical process?. Geriatr Oncol. 2014 Jan;5(1):40-48. Pubmedid: 24484717. Pmcid: PMC4527303.
  • Hurria A, Wildes T, Blair SL, Browner IS, Cohen HJ, Deshazo M, Dotan E, Edil BH, Extermann M, Ganti AK, Holmes HM, Jagsi R, Karlekar MB, Keating NL, Korc-Grodzicki B, McKoy JM, Medeiros BC, Mrozek E, O'Connor T, Rugo HS, Rupper RW, Silliman RA, Stirewalt DL, Tew WP, Walter LC, Weir AB, Bergman MA, Sundar H. Senior adult oncology, version 2.2014: clinical practice guidelines in oncology . J Natl Compr Canc Ne. 2014 Jan;12(1):82-126. Pubmedid: 24453295.
  • Wildiers H, Heeren P, Puts M, Topinkova E, Janssen-Heijnen ML, Extermann M, Falandry C, Artz A, Brain E, Colloca G, Flamaing J, Karnakis T, Kenis C, Audisio RA, Mohile S, Repetto L, Van Leeuwen B, Milisen K, Hurria A. International Society of Geriatric Oncology consensus on geriatric assessment in older patients with cancer. J Clin Oncol. 2014 Aug;32(24):2595-2603. Pubmedid: 25071125. Pmcid: PMC4876338.
  • Hurria A, Dale W, Mooney M, Rowland JH, Ballman KV, Cohen HJ, Muss HB, Schilsky RL, Ferrell B, Extermann M, Schmader KE, Mohile SG. Designing therapeutic clinical trials for older and frail adults with cancer: U13 conference recommendations. J Clin Oncol. 2014 Aug;32(24):2587-2594. Pubmedid: 25071116. Pmcid: PMC4129504.
  • Ballman KV, Mauer M, Wedding U, Mohile SG, Muss H, Extermann M, Luciani A, Cohen HJ, Hurria A, Lichtman SM, Curigliano G, Wildiers H. Reply to L.K. Mell et al. J Clin Oncol. 2014 Apr;32(10):1090-1091. Pubmedid: 24550420.
  • Wildiers H, Mauer M, Pallis A, Hurria A, Mohile SG, Luciani A, Curigliano G, Extermann M, Lichtman SM, Ballman K, Cohen HJ, Muss H, Wedding U. End points and trial design in geriatric oncology research: a joint European organization for research and treatment of cancer--Alliance for Clinical Trials in Oncology--International Society Of Geriatric Oncology position article. J Clin Oncol. 2013 Oct;31(29):3711-3718. Pubmedid: 24019549.
  • Muffly LS, Boulukos M, Swanson K, Kocherginsky M, Cerro PD, Schroeder L, Pape L, Extermann M, Van Besien K, Artz AS. Pilot study of comprehensive geriatric assessment (CGA) in allogeneic transplant: CGA captures a high prevalence of vulnerabilities in older transplant recipients. Biol Blood Marrow Tr. 2013 Mar;19(3):429-434. Pubmedid: 23160006.
  • Extermann M. Metabolic syndrome, aging, and cancer. Crit Rev Oncog. 2013 Dec;18(6):515-529. Pubmedid: 24579732.
  • Extermann M. Metabolic syndrome and cancer: from bedside to bench and back. Interdiscip Top Gerontol. 2013 Dec;38:49-60. Pubmedid: 23503515.
  • Robb C, Lee A, Jacobsen P, Dobbin KK, Extermann M. Health and personal resources in older patients with cancer undergoing chemotherapy. Geriatr Oncol. 2013 Apr;4(2):166-173. Pubmedid: 24071541. Pmcid: PMC4140217.
  • Movsas B, Extermann M. Introduction: Cancer, aging, and comorbidities. Semin Radiat Oncol. 2012 Oct;22(4):263-264. Pubmedid: 22985807.
  • Chen RC, Royce TJ, Extermann M, Reeve BB. Impact of age and comorbidity on treatment and outcomes in elderly cancer patients. Semin Radiat Oncol. 2012 Oct;22(4):265-271. Pubmedid: 22985808.
  • Extermann M. Integrating a geriatric evaluation in the clinical setting. Semin Radiat Oncol. 2012 Oct;22(4):272-276. Pubmedid: 22985809.
  • Extermann M, Boler I, Reich RR, Lyman GH, Brown RH, DeFelice J, Levine RM, Lubiner ET, Reyes P, Schreiber FJ, Balducci L. Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score. Cancer. 2012 Jul;118(13):3377-3386. Pubmedid: 22072065.
  • Extermann M, Wedding U. Comorbidity and geriatric assessment for older patients with hematologic malignancies: a review of the evidence. J Geriatr Oncol. 2012 Jan;3:50-57.
  • Hurria A, Browner IS, Cohen HJ, Denlinger CS, deShazo M, Extermann M, Ganti AK, Holland JC, Holmes HM, Karlekar MB, Keating NL, McKoy J, Medeiros BC, Mrozek E, O'Connor T, Petersdorf SH, Rugo HS, Silliman RA, Tew WP, Walter LC, Weir AB, Wildes T. Senior adult oncology. J Natl Compr Canc Ne. 2012 Feb;10(2):162-209. Pubmedid: 22308515. Pmcid: PMC3656650.
  • Liu JJ, Extermann M. Comprehensive geriatric assessment and its clinical impact in oncology. Clin Geriatr Med. 2012 Feb;28(1):19-31. Pubmedid: 22326033.
  • Dale W, Mohile SG, Eldadah BA, Trimble EL, Schilsky RL, Cohen HJ, Muss HB, Schmader KE, Ferrell B, Extermann M, Nayfield SG, Hurria A. Biological, clinical, and psychosocial correlates at the interface of cancer and aging research. J Natl Cancer Inst. 2012 Apr;104(8):581-589. Pubmedid: 22457474. Pmcid: PMC3328422.
  • Extermann M. Basic assessment of the older cancer patient. CURR TREAT OPTION ON. 2011 Sep;12(3):276-285. Pubmedid: 21656152.
  • Gore E, Bae K, Langer C, Extermann M, Movsas B, Okunieff P, Videtic G, Choy H. Phase I/II trial of a COX-2 inhibitor with limited field radiation for intermediate prognosis patients who have locally advanced non-small-cell lung cancer: radiation therapy oncology group 0213. Clin Lung Cancer. 2011 Mar;12(2):125-130. Pubmedid: 21550559.
  • Brunello A, Kapoor R, Extermann M. Hyperglycemia during chemotherapy for hematologic and solid tumors is correlated with increased toxicity. Am J Clin Oncol. 2011 Jun;34(3):292-296. Pubmedid: 20622641.
  • Janssen-Heijnen ML, Extermann M, Boler IE. Can first cycle CBCs predict older patients at very low risk of neutropenia during further chemotherapy?. Crit Rev Oncol Hematol. 2011 Jul;79(1):43-50. Pubmedid: 20685130.
  • van Waalwijk MA, van de Schans SAM, Haak HR, Extermann M, Derckson MW, Janssen-Heijnen MLG. Diabetes alone should not be a motive for withholding adjuvant chemotherapy for stage III colon cancer. J Comorbid. 2011 Jan;1:19-27.
  • van Waalwijk MA, van de Schans SAM, Haak HR, Extermann M, Dercksen WMW, Janssen-Heijnen MLG. Diabetes alone should not be a reason for withholding adjuvant chemotherapy for stage III colon cancer. J Comorb. 2011;1:19-27. Pubmedid: 29090133. Pmcid: PMC5556418.
  • Hurria A, Cohen HJ, Extermann M. Geriatric Oncology Research in the Cooperative Groups: A Report of a SIOG Special Meeting. Geriatr Oncol. 2010 Jun;1(1):40-44. Pubmedid: 21218146. Pmcid: PMC3014580.
  • Robb C, Boulware D, Overcash J, Extermann M. Patterns of care and survival in cancer patients with cognitive impairment. Crit Rev Oncol Hematol. 2010 Jun;74(3):218-224. Pubmedid: 19709899.
  • Extermann M. Geriatric oncology: an overview of progresses and challenges. Cancer Res Treat. 2011 Jul;42(2):61-68. Pubmedid: 20622959. Pmcid: PMC2901078.
  • Extermann M. Larger questions about chemotherapy in older patients. Oncology (Williston Park). 2010 Jan;24(1):92-93. Pubmedid: 20187327.
  • Kumar NB, Kazi A, Smith T, Crocker T, Yu D, Reich RR, Reddy K, Hastings S, Exterman M, Balducci L, Dalton K, Bepler G. Cancer cachexia: traditional therapies and novel molecular mechanism-based approaches to treatment. CURR TREAT OPTION ON. 2010 Dec;11(3-4):107-117. Pubmedid: 21128029. Pmcid: PMC3016925.
  • Extermann M, Crane EJ, Boulware D. Cancer in nonagenarians: Profile, treatments and outcomes. Crit Rev Oncol Hematol. 2010 Aug;75(2):160-164. Pubmedid: 20656211.
  • Luciani A, Jacobsen P, Extermann M, Foa P, Marussi D, Overcash J, BalducciL. Fatigue and functional dependence in older cancer patients. Am J Clin Oncol. 2008 Oct;31(5):424-430. Pubmedid: 18838877.
  • Simon GR, Extermann M, Chiappori A, Williams CC, Begum M, Kapoor R, Haura EB, Ismail-Khan R, Schell MJ, Antonia SJ, Bepler G. Phase 2 trial of docetaxel and gefitinib in the first-line treatment of patients with advanced nonsmall-cell lung cancer (NSCLC) who are 70 years of age or older. Cancer. 2008 May;112(9):2021-2029. Pubmedid: 18300255.
  • Extermann M, Hurria A. Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol. 2007 May;25(14):1824-1831. Pubmedid: 17488980.
  • Extermann M. Interaction between comorbidity and cancer. Cancer Control. 2007 Jan;14(1):13-22. Pubmedid: 17242667.
  • Extermann M. Connecting trains. Cancer Control. 2007 Jan;14(1):4-5. Pubmedid: 17242665.
  • Wildiers H, Kunkler I, Biganzoli L, Fracheboud J, Vlastos G, Bernard-Marty C, Hurria A, Extermann M, Girre V, Brain E, Audisio R, Bartelink H, Barton M, Giordano S, Muss H, Aapro M. Management of breast cancer in elderly individuals: recommendations of the International Society of Geriatric Oncology. Lancet Oncol. 2007 Dec;8(12):1101-1115. Pubmedid: 18054880.
  • Robb C, Haley W, Balducci L, Extermann M, Perkins E, Small B, Mortimer J. Impact of breast cancer survivorship on quality of life in older women. Crit Rev Oncol Hematol. 2007 Apr;62(1):84-91. Pubmedid: 17188505.
  • Perkins EA, Small BJ, Balducci L, Extermann M, Robb C, Haley WE. Individual differences in well-being in older breast cancer survivors. Crit Rev Oncol Hematol. 2007 Apr;62(1):74-83. Pubmedid: 17240157. Pmcid: PMC1911161.
  • Extermann M. Treating advanced breast cancer in the older woman. Oncology (Williston Park). 2006 Oct;20(11):1355-1360. Pubmedid: 17111999.
  • Artz A, Pollyea D, Kocherginsky M, Stock W, Rich E, Odenike O, ZimmermanT, Smith S, Godley L, Thirman M, Daugherty C, Extermann M, Larson R, van BesienK. Performance status and comorbidity predict transplant-related mortality after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2006 Aug;12(9):954-964. Pubmedid: 16920562.
  • Overcash J, Beckstead J, Moody L, Extermann M, Cobb S. The abbreviated comprehensive geriatric assessment (aCGA) for use in the older cancer patient as a prescreen: Scoring and interpretation. Crit Rev Oncol Hematol. 2006 Aug;59(3):205-210. Pubmedid: 16904902.
  • Naing A, Luong D, Extermann M. Methotrexate-induced status epilepticus. Am J Hematol. 2005 Sep;80(1):35-37. Pubmedid: 16138356.
  • Extermann M, Aapro M, Bernabei R, Cohen H, Droz J, Lichtman S, Mor V, Monfardini S, Repetto L, Sorbye L, Topinkova E. Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Crit Rev Oncol Hematol. 2005 Oct;55(3):241-252. Pubmedid: 16084735.
  • Extermann M. Geriatric assessment with focus on instrument selectivity for outcomes. Cancer J. 2005 Nov;11(6):474-480. Pubmedid: 16393481.
  • Extermann M, Chen H, Booth-Jones M, Meyer J, Balducci L, Jacobsen P. Pilot testing of the computerized cognitive test Microcog in chemotherapy-treated older cancer patients. Crit Rev Oncol Hematol. 2005 May;54(2):137-143. Pubmedid: 15843096.
  • Overcash J, Beckstead J, Extermann M, Cobb S. The abbreviated comprehensive geriatric assessment (aCGA): a retrospective analysis. Crit Rev Oncol Hematol. 2005 May;54(2):129-136. Pubmedid: 15843095.
  • Aapro M, Kohne C, Cohen H, Extermann M. Never too old? Age should not be a barrier to enrollment in cancer clinical trials. Oncologist. 2005 Mar;10(3):198-204. Pubmedid: 15793223.
  • Mandelblatt JS, Schechter CB, Yabroff KR, Lawrence W, Dignam J, Extermann M, Fox S, Orosz G, Silliman R, Cullen J, Balducci L. Toward optimal screening strategies for older women. Costs, benefits, and harms of breast cancer screening by age, biology, and health status. J Gen Intern Med. 2005 Jun;20(6):487-496. Pubmedid: 15987322. Pmcid: PMC1490138.
  • Extermann M. Older patients, cognitive impairment, and cancer: an increasingly frequent triad. J Natl Compr Canc Netw. 2005 Jul;3(4):593-596. Pubmedid: 16038648.
  • Carreca I, Balducci L, Extermann M. Cancer in the older person. Cancer Treat Rev. 2005 Aug;31(5):380-402. Pubmedid: 15967582.
  • Braud A, Extermann M. Biological screening and impact in elderly cancer patients. Cancer Treat Res. 2005;124:165-171. Pubmedid: 15839195.
  • Extermann M. Biological basis of the association of cancer and aging comorbidity. Cancer Treat Res. 2005;124:173-186. Pubmedid: 15839196.
  • Extermann M. Decision analysis for cancer prevention and cancer treatment in the elderly. Cancer Treat Res. 2005;124:223-232. Pubmedid: 15839198.
  • Extermann M, Meyer J, McGinnis M, Crocker T, Corcoran M, Yoder J, Haley W, Chen H, Boulware D, Balducci L. A comprehensive geriatric intervention detects multiple problems in older breast cancer patients. Crit Rev Oncol Hematol. 2004 Jan;49(1):69-75. Pubmedid: 14734156.
  • Extermann M. Management issues for elderly patients with breast cancer. CURR TREAT OPTION ON. 2004 Apr;5(2):161-169. Pubmedid: 14990210.
  • Extermann M, Bonetti M, Sledge G, O'Dwyer P, Bonomi P, Benson AB 3rd. MAX2--a convenient index to estimate the average per patient risk for chemotherapy toxicity; validation in ECOG trials. Eur J Cancer. 2004;40(8):1193-1198. Pubmedid: 15110883.
  • Extermann M, Albrand G, Chen H, Zanetta S, Schonwetter R, Zulian G, Cantor A, Droz J. Are older French patients as willing as older American patients to undertake chemotherapy?. J Clin Oncol. 2003 Sep;21(17):3214-3219. Pubmedid: 12874269.
  • Extermann M. Paclitaxel pharmacokinetics, threshold models, and dosing strategies. J Clin Oncol. 2003 Jul;21(14):2804-2805. Pubmedid: 12860962.
  • Chen H, Cantor A, Meyer J, Corcoran M, Grendys E, Cavanaugh D, AntonekS, Camarata A, Haley W, Balducci L, Extermann M. Can older cancer patients tolerate chemotherapy? A prospective pilot study. Cancer. 2003;97(4):1107-1114. Pubmedid: 12569613.
  • Extermann M. Comprehensive geriatric assessment basics for the cancer professional. J Oncol Manag. 2003;12(2):13-17. Pubmedid: 12699111.
  • Friberg M, Jennings R, Alsarraj M, Dessureault S, Cantor A, Extermann M, Mellor AL, Munn DH, Antonia SJ. Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection. Int J Cancer. 2002 Sep;101(2):151-155. Pubmedid: 12209992.
  • Antonia S, Seigne J, Diaz J, Muro-Cacho C, Extermann M, Farmelo M, Friberg M, Alsarraj M, Mahany J, Pow-Sang J, Cantor A, Janssen W. Phase I trial of a B7-1 (CD80) gene modified autologous tumor cell vaccine in combination with systemic interleukin-2 in patients with metastatic renal cell carcinoma. J Urol. 2002 May;167(5):1995-2000. Pubmedid: 11956426.
  • Extermann M, Chen H, Cantor A, Corcoran M, Meyer J, Grendys E, CavanaughD, Antonek S, Camarata A, Haley W, Balducci L. Predictors of tolerance to chemotherapy in older cancer patients: a prospective pilot study. Eur J Cancer. 2002;38(11):1466-1473. Pubmedid: 12110492.
  • Balducci L, Extermann M, Carreca I. Management of breast cancer in the older woman. Cancer Control. 2001 Sep;8(5):431-441. Pubmedid: 11579340.
  • Balducci L, Extermann M. A practical approach to the older patient with cancer: a review. Curr Probl Cancer. 2001 Jan;25(1):6-76. Pubmedid: 11261937.
  • Overcash J, Extermann M, Parr J, Perry J, Balducci L. Validity and reliability of the FACT-G scale for use in the older person with cancer. Am J Clin Oncol. 2001 Dec;24(6):591-596. Pubmedid: 11801761.
  • Extermann M. Measurement and impact of comorbidity in older cancer patients. Crit Rev Oncol Hematol. 2000 Sep;35(3):181-200. Pubmedid: 10960800.
  • Extermann M. Challenges in geriatric oncology. Cancer Control. 2000 Nov;7(6):499-500. Pubmedid: 11088059.
  • Extermann M. Measuring comorbidity in older cancer patients. Eur J Cancer. 2000 Mar;36(4):453-471. Pubmedid: 10717521.
  • Mandelblatt J, Orosz G, Yabroff K, Extermann M, Lawrence W, Yi B, Satariano W, Bloom H, Fox S, Silliman R, Fahs M, Schecther C, Muenning P, Balducci L. Screening mammography in elderly women. Research on Breast Cancer in Older Women Consortium. Jama. 2000 Jun;283(24):3202-3203. Pubmedid: 10866863.
  • Balducci L, Extermann M. Management of the frail person with advanced cancer. Crit Rev Oncol Hematol. 2000 Feb;33(2):143-148. Pubmedid: 10737376.
  • Extermann M, Aapro M. Assessment of the older cancer patient. Hematol Oncol Clin North Am. 2000 Feb;14(1):63-77, viii. Pubmedid: 10680072.
  • Balducci L, Extermann M. Cancer and aging. An evolving panorama. Hematol Oncol Clin North Am. 2000 Feb;14(1):1-16. Pubmedid: 10680068.
  • Aapro M, Extermann M, Repetto L. Evaluation of the elderly with cancer. Ann Oncol. 2000 Dec;11(Suppl 3):223-229. Pubmedid: 11079145.
  • Balducci L, Extermann M. Management of cancer in the older person: a practical approach. Oncologist. 2000 Aug;5(3):224-237. Pubmedid: 10884501.
  • Extermann M, Balducci L, Lyman G. What threshold for adjuvant therapy in older breast cancer patients?. J Clin Oncol. 2000 Apr;18(8):1709-1717. Pubmedid: 10764431.
  • Balducci L, Extermann M. Cancer in the elderly. Clin Geriatr Med. 1999;6(13):51-58.
  • Extermann M, Bacchi M, Monai N, Fopp M, Fey M, Tichelli A, Schapira M, Spertini O. Relationship between cleaved L-selectin levels and the outcome of acute myeloid leukemia. Blood. 1998 Nov;92(9):3115-3122. Pubmedid: 9787146.
  • Extermann M, Overcash J, Lyman G, Parr J, Balducci L. Comorbidity and functional status are independent in older cancer patients. J Clin Oncol. 1998;16(4):1582-1587. Pubmedid: 9552069.
  • Balducci L, Extermann M. Difficulties in treating older patients with cancer. Oncology Pract. 1998;15-18. Pubmedid: noPMID.
  • Antonia S, Extermann M, Flavell R. Immunologic nonresponsiveness to tumors. Critical Rev Onco. 1998;9:35-41. Pubmedid: 9754446.
  • Balducci L, Extermann M. Advances in cancer therapy for the older patient. Intern Med. 1997;18:79-92. Pubmedid: noPIMID.
  • Extermann M. Acute leukemia in the elderly. Clin Geriatr Med. 1997;13:227-244. Pubmedid: 9103206.
  • Balducci L, Extermann M. Cancer chemotherapy in the older person: what the medical oncologists needs to know. Cancer. 1997;80:1317-1322. Pubmedid: 9317185.
  • Balducci L, Extermann M, Fentiman I, Monfardini S, Perrone F. Should adjuvant chemotherapy be used to treat breast cancer in elderly patients (> or = 70 years of age)?. Eur J Cancer. 1997;33:1720-1724. Pubmedid: 9470824.
  • Extermann M, Balducci L, Lyman G. Optimal duration of adjuvant tamoxifen treatment in elderly breast cancer patients: influence of age, cormorbidites, and various effectiveness hypothesis on life-expectancy. Breast Dis. 1996;9:327-339.
  • Extermann M, C Regamey, L Humair, Murisier F, Rhyner K, Vonwiller H. Initial treatment of sepsis in non-neutropenic patients: ceftazidime alone versus "best guess" combined antibiotic therapy. Chemotherapy. 1995;41:306-315. Pubmedid: 7555212.
  • Zulian G, Roux E, Tiercy J, Extermann M, Diebold-Berger S, Reymond J, Helg C, Zubler R, Betticher D, Alberto P, Jeannet M, Chapuis B. Transfusion associated graft versus host disease in a patient treated with cladribine (2-chlorodeoxyadenosine): demonstration of exogenous DNA in various tissue extracts. Brit J Hemat. 1995;89:83-89. Pubmedid: 7833282.
  • Extermann M, Vogt N, Forni M, Dayer P. Radiation recall in a patient with breast cancer treated for tuberculosis. Eur J Clin Pharm. 1995;48:77-78. Pubmedid: 7621852.
  • Extermann M, Regamey C. Empirical antibiotic treatment of sepsis in non-neutropenic patients: single agent or combination therapy?. Infection. 1994;22:1-3.
  • Hayoz D, Extermann M, Odermatt B, Pugin P, Regamey C, Knecht H. Familial primary gastric lymphoma. Gut. 1993;34:136-140.
  • Extermann M. Studies of comprehensive geriatric assessment in patients with cancer. Cancer Control. 10(6):463-468. Pubmedid: 14652522.
  • International issues. In: Extermann M, Aapro M, eds. Cancer in the elderly. New York, NY: Marcel Dekker; 2000;459-476.
  • Balducci L, Extermann M. The cost of cancer prevention and treatment in the older person. In: The older cancer patient. New York, NY: Springer Publishing Company Inc; 2003;284-296.
  • Balducci L, Extermann M. Issues in the care of the older cancer patient: delayed diagnosis, inadequate treatment, and information gaps. In: The older cancer patient. New York, NY: Springer Publishing Company Inc; 2003;24-44.
  • Balducci L, Extermann M. Cancer and age. In: Haskell C, ed. Cancer treatment. Philadelphia, PA: W.B. Saunders; 2000;435-451.
  • Extermann M, Balducci L. Optimizing cancer care in the elderly: progress in geriatric oncology. Cancer Control. 10(6):440-441. Pubmedid: 14652519.
  • Extermann M, Balducci L. Practical proposals for clinical protocols in elderly patients with cancer. In: Balducci L, Lyman G, Ershler W, et al, eds. Comprehensive Geriatric Oncology. Amsterdam. Harwood Academic Publishers; 1998;263-269.
  • Balducci L, Extermann M. Cancer, carcinogenesis and aging. In: Rosenthal R, Zenilman M, Katlic M, et al, eds. Principles and practice of geriatric surgery. New York, NY: Springer Publishing Co Verlag; 2000;38-45.
  • Extermann M. Comorbidity and geriatric assessment in the elderly patient over the age of 70. Tumori. 88(1 Suppl 1):S9. Pubmedid: 11989938.