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What Are the Subtypes of Sarcoma?

Sarcoma is a kind of cancer that affects the body’s connective tissues: the bones, muscles, cartilage, blood vessels and tendons. There are two main types of sarcoma. The most common is soft tissue sarcoma, which develops in the soft tissues of the body, usually the muscles or blood vessels. The other type of sarcoma is less common and is known as bone sarcoma, because it forms in the bone.

The Most Common Subtypes of Sarcoma

Within the two main types of sarcoma, there are more than 70 different subtypes. They are classified based on where in the soft tissue or bone the cancer originated. Some of the most common subtypes of sarcoma include:

  • Osteosarcoma – Develops in cells that form bones
  • Dermatofibrosarcoma protuberans (DFSP) – Develops in the skin
  • Fibrosarcoma (fibroblastic sarcoma) – Develops in fibrous tissue
  • Chondrosarcoma – Develops in cartilage
  • Ewing’s sarcoma – Develops in bone cells or immature soft tissue
  • Rhabdomyosarcoma – Develops in cells that form skeletal muscles
  • Liposarcoma – Develops in fatty tissue
  • Synovial sarcoma – Develops in the cells near the tendons and joints
  • Pleomorphic sarcoma – Develops in the soft tissues of the abdomen, arms and legs
  • Gastrointestinal stromal tumor – Develops in the cells that line the gastrointestinal tract
  • Kaposi’s sarcoma – Develops in the cells that line lymph or blood vessels
  • Leiomyosarcoma – Develops in the muscles of organs in the pelvis and abdomen
  • Angiosarcoma – Develops in the inner lining of the blood vessels

Where Can I Get a Diagnosis and Treatment for Sarcoma?

Because there are so many types of sarcoma, it’s important to get your diagnosis and treatment at a high-volume cancer center like Moffitt Cancer Center where the treatment team is well versed in the complexity of this cancer. Our experts have unparalleled experience treating all types of sarcoma, even the most uncommon types. Once a diagnosis has been made, our multispecialty team will consider the full range of treatments available, choosing the best combination for each patient and their unique cancer.

To learn more about our approach to sarcoma treatment at Moffitt, fill out a new patient registration form online or call 1-888-663-3488. We do not require referrals.