What Are the Symptoms of Melanoma That Has Spread?

Melanoma that has spread from the skin to other areas of the body is known as metastatic melanoma. However, since melanoma often first presents itself as an abnormal mole, many people with this malignancy can receive a diagnosis before the cancer has spread. This mole may be asymmetrical, have an uneven border, have an inconsistent color, be large or change over time. A melanoma may also appear as a sore or itchy bump, a tender nodule or a patch of skin that is scaly or bleeding. In some cases, early signs of melanoma are not present. For example, if the cancer starts in a mucous membrane rather than on the skin, a mole may not be present.

Symptoms of metastatic melanoma other than a mole

Other symptoms of this type of cancer may not appear until a later stage, when the melanoma has metastasized to another area of the body. Metastatic melanoma most often spreads to the lymph nodes, brain, bones, liver or lungs, and the additional symptoms experienced at this late stage will depend on where the melanoma has spread. For example:

  • Lungs – A persistent cough or shortness of breath
  • Brain – Headaches or seizures
  • Lymph nodes – Swelling of the lymph nodes
  • Liver – Loss of appetite or unexplained weight loss
  • Bone – Bone pain or unusual fractures

What if I have metastatic melanoma symptoms?

Whether you have a suspicious mole or are experiencing some symptoms of advanced-stage melanoma, it is important to consult with a physician to receive an accurate diagnosis, as many other conditions can cause similar symptoms. At Moffitt Cancer Center, we provide a comprehensive range of screening, diagnostic, treatment and supportive care services for patients with melanoma and other types of cancer. Within our Cutaneous Oncology Program, our multispecialty team includes surgeons, dermatologists, medical oncologists and other experts who work together as a tumor board to ensure our patients receive the best possible treatment and care.

If you would like to schedule an appointment at Moffitt to discuss your metastatic melanoma symptoms, call 1-888-663-3488 or fill out a new patient registration form online. We do not require a referral to schedule an appointment.