Bladder Cancer Clinical Trials & Research

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Clinical trials offer bladder cancer patients the opportunity to be among the first to benefit from breakthrough treatment options, before they become widely available. Sometimes, it is mistakenly believed that participating in a clinical trial means that the patient will become a "guinea pig," either testing a drug or procedure that has never before been used or unknowingly receiving a placebo, but this could not be further from the truth. In reality, cancer treatments that are in the clinical trial phase have already undergone extensive testing for safety, and in the rare instances that placebos are used in clinical trials, participants are made fully aware of this possibility and are never denied access to other treatments they may need. Furthermore, clinical trial participants can choose to withdraw from the program at any time.

Are You a Candidate for a Bladder Cancer Clinical Trial?

The purpose of clinical trials, for bladder cancer or any other type of cancer, is to compare innovative new therapies with standard treatments (standard treatments that are considered the most advanced options currently available). Any patient can be considered for participation in a clinical trial, but they must meet the inclusion criteria for the particular study. These criteria may include factors such as:

  • The type of cancer
  • The patient’s gender
  • The patient’s age
  • Past treatments
  • The staging, or extent, of the cancer

For the most groundbreaking treatments and clinical trials, bladder cancer patients should look to high-volume cancer facilities, like Moffitt Cancer Center, that have a specialty program concentrated on urologic cancers. Moffitt boasts a robust clinical trials program and is home to a vast research team that’s comprised of a wide range of professionals, including physician-scientists, research data specialists and oncologists who specialize solely in the treatment of bladder cancer. For our extensive research efforts, Moffitt has been designated a National Cancer Institute Comprehensive Care Center – the only one based in Florida.

If you’d like to learn about specific bladder cancer clinical trials available at Moffitt, call 1-813-745-6100 or 1-800-679-0775 (toll-free) or submit a clinical trials inquiry form.

 

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Open Clinical Trials:

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CLINICAL TRIAL 20943

Combination of Ipi/Nivo Plus Sacituzumab Govitecan in Metastatic Cisplatin Ineligible Urothelial Carcinoma Patients

Disease Site: Other Urinary, Urinary Bladder, Urothelial Cancer

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CLINICAL TRIAL 21080

A Phase 1, Open-Label, Dose-Escalation, and Dose-Expansion Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SRK-181 Administered Alone or in Combination with a Checkpoint Inhibitor in Patients with Locally Advanced or Metastatic Solid Tumors (DRAGON)

Disease Site: Any Site, Lung, Melanoma, skin, Urinary Bladder

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CLINICAL TRIAL 21180

A First-in-Human, Two-Part, Open-Label, Clinical Study to Assess the Safety, Tolerability and Activity of Intravenous Doses of ICT01 as Monotherapy and in Combination with an Immune Checkpoint Inhibitor, in Patients with Advanced-Stage, Relapsed/Refractory Cancer (EVICTION Study)

Disease Site: Any Site, Breast, Colon, Larynx, Leukemia, other, Lip, Oral Cavity and Pharynx, Lung, Melanoma, skin, Ovary, Prostate, Stomach, Urinary Bladder

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CLINICAL TRIAL 21636

A Dose-Escalation and Expansion Study of the Safety and Efficacy of XL092 in Combination with Immuno-Oncology Agents in Subjects with Unresectable Advanced or Metastatic Solid Tumors

Disease Site: Breast, Colon, Prostate, Urinary Bladder

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CLINICAL TRIAL 21698

A Phase 2, Multicenter, Open-Label Study of Lurbinectedin Efficacy and Safety in Participants with Advanced or Metastatic Solid Tumors

Disease Site: Ill-Defined Sites, Lung, Urinary Bladder

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CLINICAL TRIAL 21894

Phase 1 Clinical Trial of lntravesical Adoptive Cell Therapy {ACT) with Tumor Infiltrating Lymphocytes (TIL) for Patients with BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer {NMIBC)

Disease Site: Urinary Bladder

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CLINICAL TRIAL 21913

A Phase 3 Study of CG0070 In Patients with Non- Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus Calmette-Guerin (BCG)

Disease Site: Urinary Bladder

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