Jane <span>L.</span> Messina
Researcher

Jane L. Messina

Overview

Dr. Messina's research interests include pathology of the sentinel node, biomarkers of prognosis in cutaneous melanoma, and etiology and treatment of Merkel cell carcinoma.

Discipline

    • Anatomic Pathology
    • Melanoma Research Center of Excellence
    • Immunology
    • Center for Infection Research in Cancer

Education & Training

    • University of South Florida College of Medicine, MD
    • USF Affiliated Hospitals, Resident - Anatomic and Clinical Pathology
    • USF Departments of Pathology/Dermatology, Fellow - Dermatopathology
Research

Dr. Messina has published over 150 papers in peer-reviewed journals. Her research covers pathologic evaluation of sentinel lymph nodes, special applications of sentinel lymphadenectomy, and molecular studies of spectrum of melanocytic neoplasia.

Publications

  • Beverido LG, Nanjappa S, Braswell DS, Messina JL, Greene J. Eczema Herpeticum: Case Report and Review of Literature. Infect Dis Clin Prac. 2017 Mar;25(2):94-96.
  • Shenoy R, Nanjappa S, Eaton K, Prieto-Granada C, Messina J, Greene J. Purpura Fulminans: A Case Report and Review of All Causes. Infect Dis Clin Prac. 2017 Mar;25(2):100-104.
  • Glazer ES, Porubsky CF, Francis JD, Ibanez J, Castner N, Messina JL, Sarnaik AA, Harrington MA, Cruse CW, Sondak VK, Zager JS. Treatment of Head and Neck Melanoma In Situ With Staged Contoured Marginal Excisions. Ann Plast Surg. 2017 Jun;78(6):663-667. Pubmedid: 27984218. Pmcid: PMC5425303.
  • Sondak VK, Messina JL, Zager JS. Selecting Patients With Thin Melanoma for Sentinel Lymph Node Biopsy-This Time It's Personal. JAMA Dermatol. 2017 Jul. Pubmedid: 28724141.
  • Strom T, Naghavi AO, Messina JL, Kim S, Torres-Roca JF, Russell J, Sondak VK, Padhya TA, Trotti AM, Caudell JJ, Harrison LB. Improved local and regional control with radiotherapy for Merkel cell carcinoma of the head and neck. Head Neck. 2017 Jan;39(1):48-55. Pubmedid: 27300153.
  • Sudenga SL, Torres BN, Fulp WJ, Silva R, Villa LL, Lazcano-Ponce E, Ingles DJ, Stoler M, Messina JL, Abrahamsen M, Baggio ML, Salmeron J, Quiterio M, Giuliano AR. Country-specific HPV-related genital disease among men residing in Brazil, Mexico and The United States: The HIM study. Int J Cancer. 2017 Jan;140(2):337-345. Pubmedid: 27681815.
  • Prieto-Granada CN, Zhang L, Antonescu CR, Henneberry JM, Messina JL. Primary cutaneous adenoid cystic carcinoma with MYB aberrations: report of three cases and comprehensive review of the literature. J Cutan Pathol. 2017 Feb;44(2):201-209. Pubmedid: 27859477.
  • Strom T, Torres-Roca JF, Parekh A, Naghavi AO, Caudell JJ, Oliver DE, Messina JL, Khushalani NI, Zager JS, Sarnaik A, Mulé JJ, Trotti AM, Eschrich SA, Sondak VK, Harrison LB. Regional Radiation Therapy Impacts Outcome for Node-Positive Cutaneous Melanoma. J Natl Compr Canc Ne. 2017 Apr;15(4):473-482. Pubmedid: 28404758.
  • Vivar KL, Deschaine M, Messina J, Divine JM, Rabionet A, Patel N, Harrington MA, Seminario-Vidal L. Epidermal programmed cell death-ligand 1 expression in TEN associated with nivolumab therapy. J Cutan Pathol. 2017 Apr;44(4):381-384. Pubmedid: 28000240.
  • Sondak VK, Messina JL. Prediction is Difficult, Especially About the Future: Clinical Prognostic Tools in Melanoma. Ann Surg Oncol. 2016 Sep;23(9):2730-2732. Pubmedid: 27198510.
  • Pierce Campbell CM, Gheit T, Tommasino M, Lin HY, Torres BN, Messina JL, Stoler MH, Rollison DE, Sirak BA, Abrahamsen M, Carvalho da Silva RJ, Sichero L, Villa LL, Lazcano-Ponce E, Giuliano AR. Cutaneous beta human papillomaviruses and the development of male external genital lesions: A case-control study nested within the HIM Study. Virology. 2016 Oct;497:314-322. Pubmedid: 27518539.
  • Parekh A, Strom T, Naghavi AO, Caudell JJ, Zager JS, Messina JL, Torres-Roca JF, Sondak VK, Trotti A, Harrison LB. Does Regional Radiation Therapy Impact Outcome for High-Risk, Node-Positive Cutaneous Melanoma?. Int J Radiat Oncol Biol Phys. 2016 Oct;96(2S):S157. Pubmedid: 27675666.
  • Strom T, Carr M, Zager JS, Naghavi A, Smith FO, Cruse CW, Messina JL, Russell J, Rao NG, Fulp W, Kim S, Torres-Roca JF, Padhya TA, Sondak VK, Trotti AM, Harrison LB, Caudell JJ. Radiation Therapy is Associated with Improved Outcomes in Merkel Cell Carcinoma. Ann Surg Oncol. 2016 Oct;23(11):3572-3578. Pubmedid: 27251134.
  • Bennett AE, Fenske NA, Rodriguez-Waitkus P, Messina JL. IgG4-related skin disease may have distinct systemic manifestations: a systematic review. Int J Dermatol. 2016 Nov;55(11):1184-1195. Pubmedid: 27419384.
  • Hampras SS, Reed RA, Bezalel S, Cameron M, Cherpelis B, Fenske N, Sondak VK, Messina J, Tommasino M, Gheit T, Rollison DE. Cutaneous Human Papillomavirus Infection and Development of Subsequent Squamous Cell Carcinoma of the Skin. J Skin Cancer. 2016 Nov;2016:1368103. Pubmedid: 27891253. Pmcid: PMC5116506.
  • Shah S, Nanjappa S, Messina J, Greene J. Cutaneous Leishmaniasis Successfully Treated by Liposomal Amphotericin B: A Case Report and Review of the Literature. Infect Dis Clin Prac. 2016 Nov;24(6):e76-e72.
  • Fedorenko IV, Abel EV, Koomen JM, Fang B, Wood ER, Chen YA, Fisher KJ, Iyengar S, Dahlman KB, Wargo JA, Flaherty KT, Sosman JA, Sondak VK, Messina JL, Gibney GT, Smalley KS. Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells. Oncogene. 2016 Mar;35(10):1225-1235. Pubmedid: 26073081. Pmcid: PMC4679729.
  • Doepker MP, Thompson ZJ, Fisher KJ, Yamamoto M, Nethers KW, Harb JN, Applebaum MA, Gonzalez RJ, Sarnaik AA, Messina JL, Sondak VK, Zager JS. Is a Wider Margin (2 cm vs. 1 cm) for a 1.01-2.0 mm Melanoma Necessary?. Ann Surg Oncol. 2016 Jul;23(7):2336-2342. Pubmedid: 26957503. Pmcid: PMC4904729.
  • Vyas NS, Markow M, Prieto-Granada C, Gaudi S, Turner L, Rodriguez-Waitkus P, Messina JL, Jukic DM. Comparing whole slide digital images versus traditional glass slides in the detection of common microscopic features seen in dermatitis. J Pathol Inform. 2016 Jul;7:30. Pubmedid: 27563489. Pmcid: PMC4977977.
  • Hung T, Argenyi Z, Erickson L, Guitart J, Horenstein MG, Lowe L, Messina J, Piepkorn MW, Prieto VG, Rabkin MS, Schmidt B, Selim MA, Shea CR, Trotter MJ, Barnhill RL. Cellular Blue Nevomelanocytic Lesions: Analysis of Clinical, Histological, and Outcome Data in 37 Cases. Am J Dermatopathxxx. 2016 Jul;38(7):499-503. Pubmedid: 26909585.
  • Sudenga SL, Ingles DJ, Pierce Campbell CM, Lin HY, Fulp WJ, Messina JL, Stoler MH, Abrahamsen M, Villa LL, Lazcano-Ponce E, Giuliano AR. Genital Human Papillomavirus Infection Progression to External Genital Lesions: The HIM Study. Eur Urol. 2016 Jan;69(1):166-173. Pubmedid: 26051441. Pmcid: PMC4670812.
  • Mihic-Probst D, Shea C, Duncan L, de la Fouchardiere A, Landman G, Landsberg J, Ven den Oord J, Lowe L, Cook MG, Jung Yun S, Clarke L, Messina J, Elder DE, Barnhill RL. Update on Thin Melanoma: Outcome of an International Workshop. Adv Anat Pathol. 2016 Jan;23(1):24-29. Pubmedid: 26645459.
  • Sreeraman Kumar R, Messina JL, Reed D, Navid F, Sondak VK. Pediatric Melanoma and Atypical Melanocytic Neoplasms. Cancer Treat Res. 2016 Jan;167:331-369. Pubmedid: 26601871.
  • Doepker MP, Thompson ZJ, Harb JN, Messina JL, Puleo CA, Egan KM, Sarnaik AA, Gonzalez RJ, Sondak VK, Zager JS. Dermal melanoma: A report on prognosis, outcomes, and the utility of sentinel lymph node biopsy. J Surg Oncol. 2016 Jan;113(1):98-102. Pubmedid: 26661407. Pmcid: PMC4904728.
  • Sloot S, Zager JS, Kudchadkar RR, Messina JL, Benedict JJ, Gonzalez RJ, DeConti R, Turner LM, McCardle T, Smalley KS, Weber JS, Sondak VK, Gibney GT. BRAF inhibition for advanced locoregional BRAF V600E mutant melanoma: a potential neoadjuvant strategy. Melanoma Res. 2016 Feb;26(1):83-87. Pubmedid: 26731560.
  • Hassani J, Porubsky C, Berman C, Zager J, Messina J, Henderson-Jackson E. Intraperitoneal Rosai-Dorfman disease associated with clear cell sarcoma: first case report. Pathology. 2016 Dec;48(7):742-744. Pubmedid: 27814905.
  • Lott JP, Elmore JG, Zhao GA, Knezevich SR, Frederick PD, Reisch LM, Chu EY, Cook MG, Duncan LM, Elenitsas R, Gerami P, Landman G, Lowe L, Messina JL, Mihm MC, van den Oord JJ, Rabkin MS, Schmidt B, Shea CR, Yun SJ, Xu GX, Piepkorn MW, Elder DE, Barnhill RL. Evaluation of the Melanocytic Pathology Assessment Tool and Hierarchy for Diagnosis (MPATH-Dx) classification scheme for diagnosis of cutaneous melanocytic neoplasms: Results from the International Melanoma Pathology Study Group. J Am Acad Dermatol. 2016 Aug;75(2):356-363. Pubmedid: 27189823. Pmcid: PMC4958559.
  • Prieto-Granada CN, Wiesner T, Messina JL, Jungbluth AA, Chi P, Antonescu CR. Loss of H3K27me3 Expression Is a Highly Sensitive Marker for Sporadic and Radiation-induced MPNST. Am J Surg Pathol. 2016 Apr;40(4):479-489. Pubmedid: 26645727. Pmcid: PMC4882106.
  • Sung H, Kanchi KL, Wang X, Hill KS, Messina JL, Lee JH, Kim Y, Dees ND, Ding L, Teer JK, Yang S, Sarnaik AA, Sondak VK, Mulé JJ, Wilson RK, Weber JS, Kim M. Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation. Oncotarget. 2016 Apr;7(17):23885-23896. Pubmedid: 26993606. Pmcid: PMC5029671.
  • Sondak VK, Reed D, Messina JL. A Comprehensive Approach to Pediatric Atypical Melanocytic Neoplasms with Comment on the Role of Sentinel Lymph Node Biopsy. Crit Rev Oncog. 2016;21(1-2):25-36. Pubmedid: 27481000.
  • Smith FO, Yue B, Marzban SS, Walls BL, Carr M, Jackson RS, Puleo CA, Padhya T, Cruse CW, Gonzalez RJ, Sarnaik AA, Schell MJ, DeConti RC, Messina JL, Sondak VK, Zager JS. Both tumor depth and diameter are predictive of sentinel lymph node status and survival in Merkel cell carcinoma. Cancer. 2015 Sep;121(18):3252-3260. Pubmedid: 26038193. Pmcid: PMC4904725.
  • Phadke M, Gibney GT, Rich CJ, Fedorenko IV, Chen Ann Y, Kudchadkar RR, Sondak VK, Weber J, Messina JL, Smalley KS. XL888 Limits Vemurafenib-Induced Proliferative Skin Events by Suppressing Paradoxical MAPK Activation. J Invest Dermatol. 2015 Oct;135(10):2542-2544. Pubmedid: 26039542. Pmcid: PMC4567904.
  • Hampras SS, Michel A, Schmitt M, Waterboer T, Kranz L, Gheit T, Fisher K, Sondak VK, Messina J, Fenske N, Cherpelis B, Tommasino M, Pawlita M, Rollison DE. Merkel cell polyomavirus (MCV) T-antigen seroreactivity, MCV DNA in eyebrow hairs, and squamous cell carcinoma. Infect Agent Cancer. 2015 Oct;10:35. Pubmedid: 26483848. Pmcid: PMC4610041.
  • Vyas NS, Pierce Campbell CM, Mathew R, Abrahamsen M, Van der Kooi K, Jukic DM, Stoler MH, Villa LL, da Silva RC, Lazcano-Ponce E, Quiterio M, Salmeron J, Sirak BA, Ingles DJ, Giuliano AR, Messina JL. Role of histological findings and pathologic diagnosis for detection of human papillomavirus infection in men. J Med Virol. 2015 Oct;87(10):1777-1787. Pubmedid: 25945468. Pmcid: PMC4780420.
  • Yamamoto M, Fisher KJ, Wong JY, Koscso JM, Konstantinovic MA, Govsyeyev N, Messina JL, Sarnaik AA, Cruse CW, Gonzalez RJ, Sondak VK, Zager JS. Sentinel lymph node biopsy is indicated for patients with thick clinically lymph node-negative melanoma. Cancer. 2015 May;121(10):1628-1636. Pubmedid: 25677366. Pmcid: PMC4515965.
  • Paraiso KH, Thakur MD, Fang B, Koomen JM, Fedorenko IV, John JK, Tsao H, Flaherty KT, Sondak VK, Messina JL, Pasquale EB, Villagra A, Rao UN, Kirkwood JM, Meier F, Sloot S, Gibney GT, Stuart D, Tawbi H, Smalley KS. Ligand-independent EPHA2 signaling drives the adoption of a targeted therapy-mediated metastatic melanoma phenotype. Cancer Discov. 2015 Mar;5(3):264-273. Pubmedid: 25542447. Pmcid: PMC4355213.
  • Han D, Han G, Zhao X, Rao NG, Messina JL, Marzban SS, Sarnaik AA, Cruse CW, Sondak VK, Zager JS. Clinicopathologic predictors of survival in patients with desmoplastic melanoma. PLoS One. 2015 Mar;10(3):e0119716. Pubmedid: 25811671. Pmcid: PMC4374691.
  • Ching JA, Curtis HL, Braue JA, Kudchadkar RR, Mendoza TI, Messina JL, Cruse CW, Smith DJ, Harrington MA. The impact of neoadjuvant hedgehog inhibitor therapy on the surgical treatment of extensive Basal cell carcinoma. Ann Plast Surg. 2015 Jun;74 Suppl 4:S193-S197. Pubmedid: 25695449.
  • Messina JL, Rosa M. Pathologic evaluation of sentinel nodes. Cancer J. 2015 Jan;21(1):33-38. Pubmedid: 25611778.
  • Hampras SS, Rollison DE, Tommasino M, Gheit T, Schabath MB, Messina JL, Fenske NA, Cherpelis BS, Sondak VK, Iannacone MR, Schmitt M, Pawlita M. Genetic variations in the epidermodysplasia verruciformis (EVER/TMC) genes, cutaneous human papillomavirus infection and squamous cell carcinoma of the skin. Br J Dermatol. 2015 Dec;173(6):1532-1535. Pubmedid: 26126409. Pmcid: PMC4695259.
  • Fedorenko IV, Wargo JA, Flaherty KT, Messina JL, Smalley KS. BRAF Inhibition Generates a Host-Tumor Niche that Mediates Therapeutic Escape. J Invest Dermatol. 2015 Dec;135(12):3115-3124. Pubmedid: 26302068. Pmcid: PMC4648653.
  • Ingles DJ, Pierce Campbell CM, Messina JA, Stoler MH, Lin HY, Fulp WJ, Abrahamsen M, Sirak BA, O'Keefe MT, Papenfuss M, Gage C, da Silva RC, Sosa RG, Juarez OR, Villa LL, Ponce EL, Giuliano AR. Human papillomavirus virus (HPV) genotype- and age-specific analyses of external genital lesions among men in the HPV Infection in Men (HIM) Study. J Infect Dis. 2015 Apr;211(7):1060-1067. Pubmedid: 25344518. Pmcid: PMC4432433.
  • Clarke LE, Bryan Warf M, Flake DD, Hartman AR, Tahan S, Shea CR, Gerami P, Messina J, Florell SR, Wenstrup RJ, Rushton K, Roundy KM, Rock C, Roa B, Kolquist KA, Gutin A, Billings S, Leachman S. Clinical validation of a gene expression signature that differentiates benign nevi from malignant melanoma. J Cutan Pathol. 2015 Apr;42(4):244-252. Pubmedid: 25727210.
  • Graham JM, Bartlett KB, Gonzalez A, Messina JL, Shenefelt PD. Primary cutaneous nocardiosis in an immunocompetent host following laser resurfacing. J Am Acad Dermatol. 2014 Sep;71(3):e93-e94. Pubmedid: 25128144.
  • Luria L, Nguyen J, Zhou J, Jaglal M, Sokol L, Messina JL, Coppola D, Zhang L. Manifestations of gastrointestinal plasmablastic lymphoma: a case series with literature review. World J Gastroenterol. 2014 Sep;20(33):11894-11903. Pubmedid: 25206297. Pmcid: PMC4155383.
  • Sondak VK, Messina JL. Unusual presentations of melanoma: melanoma of unknown primary site, melanoma arising in childhood, and melanoma arising in the eye and on mucosal surfaces. Surg Clin N Am. 2014 Oct;94(5):1059-73, ix. Pubmedid: 25245968.
  • Ching JA, Curtis HL, Braue JA, Kudchadkar R, Mendoza TI, Messina JL, Cruse CW, Harrington MA. The impact of neoadjuvant hedgehog inhibitor therapy on the surgical treatment of extensive Basal cell carcinoma. Plast Reconstr Surg. 2014 Oct;134(4 Suppl 1):138-139. Pubmedid: 25254869.
  • Sun J, Lu F, He H, Shen J, Messina J, Mathew R, Wang D, Sarnaik AA, Chang WC, Kim M, Cheng H, Yang S. STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion. J Cell Biol. 2014 Nov;207(4):535-548. Pubmedid: 25404747. Pmcid: PMC4242838.
  • Iannacone MR, Gheit T, Pfister H, Giuliano AR, Messina JL, Fenske NA, Cherpelis BS, Sondak VK, Roetzheim RG, Silling S, Pawlita M, Tommasino M, Rollison DE. Case-control study of genus-beta human papillomaviruses in plucked eyebrow hairs and cutaneous squamous cell carcinoma. Int J Cancer. 2014 May;134(9):2231-2244. Pubmedid: 24136717. Pmcid: PMC4545525.
  • Strom T, Caudell JJ, Han D, Zager JS, Yu D, Cruse CW, Marzban SS, Messina JL, Trotti AM, Sondak VK, Rao NG. Radiotherapy influences local control in patients with desmoplastic melanoma. Cancer. 2014 May;120(9):1369-1378. Pubmedid: 24142775. Pmcid: PMC4515972.
  • Rebecca VW, Massaro RR, Fedorenko IV, Sondak VK, Anderson AR, Kim E, Amavaradi RK, Maria-Engler SS, Messina JL, Gibney GT, Kudchadkar RR, Smalley KS. Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in BRAF wild-type melanoma. Pigment Cell Melanoma Res. 2014 May;27(3):465-478. Pubmedid: 24490764. Pmcid: PMC3988257.
  • Zager JS, Messina JL, Glass LF, Sondak VK. Unanswered Questions in the Management of Stage I-III Merkel Cell Carcinoma. J Natl Compr Canc Ne. 2014 Mar;12(3):425-431. Pubmedid: 24616546.
  • Thareja S, Zager JS, Sadhwani D, Thareja S, Chen R, Marzban S, Jukic DM, Glass LF, Messina J. Analysis of tumor mitotic rate in thin metastatic melanomas compared with thin melanomas without metastasis using both the hematoxylin and eosin and anti-phosphohistone 3 IHC stain. Am J Dermatopathxxx. 2014 Jan;36(1):64-67. Pubmedid: 24451214.
  • Flannery MT, Messina JL, Bowman K. Umbilical endometriosis. Am J Med Sci. 2013 Sep;346(3):236. Pubmedid: 22874623.
  • Anic GM, Messina JL, Stoler MH, Rollison DE, Stockwell H, Villa LL, Lazcano-Ponce E, Gage C, Silva RJ, Baggio ML, Salmerón J, Giuliano AR. Concordance of human papillomavirus types detected on the surface and in the tissue of genital lesions in men. J Med Virol. 2013 Sep;85(9):1561-1566. Pubmedid: 23852680. Pmcid: PMC3879682.
  • Perez MC, Padhya TA, Messina JL, Jackson RS, Gonzalez RJ, Bui MM, Letson GD, Cruse CW, Lavey RS, Cheong D, Forster MR, Fulp WJ, Sondak VK, Zager JS. Cutaneous angiosarcoma: a single-institution experience. Ann Surg Oncol. 2013 Oct;20(11):3391-3397. Pubmedid: 23835652. Pmcid: PMC4509495.
  • Deneve JL, Messina JL, Bui MM, Marzban SS, Letson GD, Cheong D, Gonzalez RJ, Sondak VK, Zager JS. Cutaneous leiomyosarcoma: treatment and outcomes with a standardized margin of resection. Cancer Control. 2013 Oct;20(4):307-312. Pubmedid: 24077407. Pmcid: PMC4504421.
  • Etzkorn JR, Parikh RP, Marzban SS, Law K, Davis AH, Rawal B, Schell MJ, Sondak VK, Messina JL, Rendina LE, Zager JS, Lien MH. Identifying risk factors using a skin cancer screening program. Cancer Control. 2013 Oct;20(4):248-254. Pubmedid: 24077401. Pmcid: PMC4516026.
  • Averbook BJ, Lee SJ, Delman KA, Gow KW, Zager JS, Sondak VK, Messina J, Sabel M, Pittelkow M, Ecker PM, Markovic SN, Swetter SM, Leachman SA, Testori A, Curiel-Lewandrowski C, Go RS, Jukic DM, Kirkwood JM. Pediatric melanoma: analysis of an international registry. Cancer. 2013 Nov;119(22):4012-4019. Pubmedid: 24022819. Pmcid: PMC4096292.
  • Iannacone MR, Wang W, Stockwell HG, O'Rourke K, Giuliano AR, Sondak VK, Messina JL, Roetzheim RG, Cherpelis BS, Fenske NA, Rollison DE. Patterns and timing of sunlight exposure and risk of basal cell and squamous cell carcinomas of the skin--a case-control study. BMC Cancer. 2013 May;12:417. Pubmedid: 22994655. Pmcid: PMC3517361.
  • Park JY, Amankwah EK, Anic GM, Lin HY, Walls B, Park H, Krebs K, Madden M, Maddox K, Marzban S, Fang S, Chen W, Lee JE, Wei Q, Amos CI, Messina JL, Sondak VK, Sellers TA, Egan KM. Gene variants in angiogenesis and lymphangiogenesis and cutaneous melanoma progression. Cancer Epidemiol Biomarkers Prev. 2013 May;22(5):827-834. Pubmedid: 23462921. Pmcid: PMC3708315.
  • Held L, Eigentler TK, Metzler G, Leiter U, Messina JL, Glass LF, Garbe C, Bauer J. Proliferative Activity, Chromosomal Aberrations, and Tumor-Specific Mutations in the Differential Diagnosis between Blue Nevi and Melanoma. Am J Pathol. 2013 Mar;182(3):640-645. Pubmedid: 23261261.
  • Messina JL, Fenstermacher DA, Eschrich S, Qu X, Berglund AE, Lloyd MC, Schell MJ, Sondak VK, Weber JS, Mulé JJ. 12-Chemokine gene signature identifies lymph node-like structures in melanoma: potential for patient selection for immunotherapy?. Sci Rep. 2013 Mar;2:765. Pubmedid: 23097687. Pmcid: PMC3479449.
  • Iannacone MR, Gheit T, Waterboer T, Giuliano AR, Messina JL, Fenske NA, Cherpelis BS, Sondak VK, Roetzheim RG, Ferrer-Gil S, Michael KM, McKay-Chopin S, Pawlita M, Tommasino M, Rollison DE. Case-control study of cutaneous human papillomavirus infection in Basal cell carcinoma of the skin. J Invest Dermatol. 2013 Jun;133(6):1512-1520. Pubmedid: 23303448. Pmcid: PMC4545594.
  • Reed D, Kudchadkar R, Zager JS, Sondak VK, Messina JL. Controversies in the evaluation and management of atypical melanocytic proliferations in children, adolescents, and young adults. J Natl Compr Canc Ne. 2013 Jun;11(6):679-686. Pubmedid: 23744867. Pmcid: PMC4530628.
  • Iarrobino A, Messina JL, Kudchadkar R, Sondak VK. Emergence of a squamous cell carcinoma phenotype following treatment of metastatic basal cell carcinoma with vismodegib. J Am Acad Dermatol. 2013 Jul;69(1):e33-e34. Pubmedid: 23768306.
  • Han D, Zager JS, Yu D, Zhao X, Walls B, Marzban SS, Rao NG, Sondak VK, Messina JL. Desmoplastic melanoma: is there a role for sentinel lymph node biopsy?. Ann Surg Oncol. 2013 Jul;20(7):2345-2351. Pubmedid: 23389470. Pmcid: PMC4503324.
  • Gibney GT, Messina JL, Fedorenko IV, Sondak VK, Smalley KS. Paradoxical oncogenesis--the long-term effects of BRAF inhibition in melanoma. Nat Rev Clin Oncol. 2013 Jul;10(7):390-399. Pubmedid: 23712190. Pmcid: PMC3983565.
  • Saitta P, Cook CE, Messina JL, Brancaccio R, Wu BC, Grekin SK, Holland J. Is there a true concern regarding the use of hair dye and malignancy development?: a review of the epidemiological evidence relating personal hair dye use to the risk of malignancy. J Clin Aesthet Dermatol. 2013 Jan;6(1):39-46. Pubmedid: 23320124. Pmcid: PMC3543291.
  • Sondak VK, King DW, Zager JS, Schneebaum S, Kim J, Leong SP, Faries MB, Averbook BJ, Martinez SR, Puleo CA, Messina JL, Christman L, Wallace AM. Combined analysis of phase III trials evaluating [⁹⁹mTc]tilmanocept and vital blue dye for identification of sentinel lymph nodes in clinically node-negative cutaneous melanoma. Ann Surg Oncol. 2013 Feb;20(2):680-688. Pubmedid: 23054107. Pmcid: PMC3560941.
  • Han D, Zager JS, Shyr Y, Chen H, Berry LD, Iyengar S, Djulbegovic M, Weber JL, Marzban SS, Sondak VK, Messina JL, Vetto JT, White RL, Pockaj B, Mozzillo N, Charney KJ, Avisar E, Krouse R, Kashani-Sabet M, Leong SP. Clinicopathologic predictors of sentinel lymph node metastasis in thin melanoma. J Clin Oncol. 2013 Dec;31(35):4387-4393. Pubmedid: 24190111.
  • Kim E, Rebecca VW, Fedorenko IV, Messina JL, Mathew R, Maria-Engler SS, Basanta D, Smalley KS, Anderson AR. Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach. Cancer Res. 2013 Dec;73(23):6874-6885. Pubmedid: 24080279. Pmcid: PMC3926439.
  • Pierce Campbell CM, Messina JL, Stoler MH, Jukic DM, Tommasino M, Gheit T, Rollison DE, Sichero L, Sirak BA, Ingles DJ, Abrahamsen M, Lu B, Villa LL, Lazcano-Ponce E, Giuliano AR. Cutaneous human papillomavirus types detected on the surface of male external genital lesions: a case series within the HPV Infection in Men Study. J Clin Virol. 2013 Dec;58(4):652-659. Pubmedid: 24210970. Pmcid: PMC3866698.
  • Anic GM, Sondak VK, Messina JL, Fenske NA, Zager JS, Cherpelis BS, Lee JH, Fulp WJ, Epling-Burnette PK, Park JY, Rollison DE. Telomere length and risk of melanoma, squamous cell carcinoma, and basal cell carcinoma. Cancer Epidemiol. 2013 Aug;37(4):434-439. Pubmedid: 23523330. Pmcid: PMC3679277.
  • Farma JM, Zager JS, Barnica-Elvir V, Puleo CA, Marzban SS, Rollison DE, Messina JL, Sondak VK. A collision of diseases: chronic lymphocytic leukemia discovered during lymph node biopsy for melanoma. Ann Surg Oncol. 2013 Apr;20(4):1360-1364. Pubmedid: 23179994. Pmcid: PMC4606461.
  • Han D, Yu D, Zhao X, Marzban SS, Messina JL, Gonzalez RJ, Wayne Cruse C, Sarnaik AA, Puleo C, Sondak VK, Zager JS. Sentinel node biopsy is indicated for thin melanomas ≥0.76 mm. Ann Surg Oncol. 2012 Oct;19(11):3335-3342. Pubmedid: 22766986. Pmcid: PMC4504019.
  • Sondak VK, Zager JS, Messina JL. Primary tumor thickness as a prognostic factor in merkel cell carcinoma: the next big thing?. Ann Surg Oncol. 2012 Oct;19(11):3307-3309. Pubmedid: 22825775.
  • Han D, Zager JS, Han G, Marzban SS, Puleo CA, Sarnaik AA, Reed D, Messina JL, Sondak VK. The unique clinical characteristics of melanoma diagnosed in children. Ann Surg Oncol. 2012 Nov;19(12):3888-3895. Pubmedid: 22864798. Pmcid: PMC4519977.
  • Knapp CF, Mathew R, Messina JL, Lien MH. CD4/CD8 Dual-Positive Mycosis Fungoides: A Previously Unrecognized Variant. Am J Dermatopathol. 2012 May;34(3):e37-e39. Pubmedid: 22356917.
  • Mills OL, Marzban S, Zager JS, Sondak VK, Messina JL. Sentinel node biopsy in atypical melanocytic neoplasms in childhood: a single institution experience in 24 patients. J Cutan Pathol. 2012 Mar;39(3):331-336. Pubmedid: 22335592.
  • Deneve JL, Messina JL, Marzban SS, Gonzalez RJ, Walls BM, Fisher KJ, Ann Chen Y , Wayne Cruse C, Sondak VK, Zager JS. Merkel cell carcinoma of unknown primary origin. Ann Surg Oncol. 2012 Jul;19(7):2360-2366. Pubmedid: 22271206. Pmcid: PMC4504007.
  • Mathew RA, Bennett JM, Liu JJ, Komrokji RS, Lancet JE, Naghashpour M, Messina JL, List AF, Moscinski LC, Zhang L. Cutaneous manifestations in CMML: Indication of disease acceleration or transformation to AML and review of the literature. Leuk Res. 2012 Jan;36(1):72-80. Pubmedid: 21782240.
  • Smalley KS, Aplin AE, Flaherty KT, Hoeller C, Bosserhoff AK, Haass NK, Bosenberg M, Ribas A, Barnhill R, Kudchadkar R, Messina JL. Meeting report from the 2011 International Melanoma Congress, Tampa, Florida. Pigment Cell Melanoma Res. 2012 Jan;25(1):E1-11. Pubmedid: 22117673.
  • Rollison DE, Giuliano AR, Messina JL, Fenske NA, Cherpelis BS, Sondak VK, Roetzheim RG, Iannacone MR, Michael KM, Gheit T, Waterboer T, Tommasino M, Pawlita M. Case-control study of Merkel cell polyomavirus infection and cutaneous squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev. 2012 Jan;21(1):74-81. Pubmedid: 22016472. Pmcid: PMC4543303.
  • Algazi AP, Weber JS, Andrews SC, Urbas P, Munster PN, DeConti RC, Hwang J, Sondak VK, Messina JL, McCalmont T, Daud AI. Phase I clinical trial of the Src inhibitor dasatinib with dacarbazine in metastatic melanoma. Brit J Cancer. 2012 Jan;106(1):85-91. Pubmedid: 22127285. Pmcid: PMC3251861.
  • Rollison DE, Iannacone MR, Messina JL, Glass LF, Giuliano AR, Roetzheim RG, Cherpelis BS, Fenske NA, Jonathan KA, Sondak VK. Case-control study of smoking and non-melanoma skin cancer. Cancer Causes Control. 2012 Feb;23(2):245-254. Pubmedid: 22101452.
  • van der Kooi K, Glass LF, Messina JL, Trimble JS. Keratosis pilaris-like eruption observed during the experimental PLX 4032 studies. J Am Acad Dermatol. 2012 Dec;67(6):e286-e287. Pubmedid: 23158643.
  • John JK, Paraiso KH, Rebecca VW, Cantini LP, Abel EV, Pagano N, Meggers E, Mathew R, Krepler C, Izumi V, Fang B, Koomen JM, Messina JL, Herlyn M, Smalley KS. GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation. J Invest Dermatol. 2012 Dec;132(12):2818-2827. Pubmedid: 22810307. Pmcid: PMC3479306.
  • Iannacone MR, Gheit T, Waterboer T, Giuliano AR, Messina JL, Fenske NA, Cherpelis BS, Sondak VK, Roetzheim RG, Michael KM, Tommasino M, Pawlita M, Rollison DE. Case-control study of cutaneous human papillomaviruses in squamous cell carcinoma of the skin. Cancer Epidemiol Biomarkers Prev. 2012 Aug;21(8):1303-1313. Pubmedid: 22707711. Pmcid: PMC4543310.
  • Iannacone MR, Wang W, Stockwell HG, O'Rourke K, Giuliano AR, Sondak VK, Messina JL, Roetzheim RG, Cherpelis BS, Fenske NA, Michael KM, Waterboer T, Pawlita M, Rollison DE. Sunlight exposure and cutaneous human papillomavirus seroreactivity in basal cell and squamous cell carcinomas of the skin. J Infect Dis. 2012 Aug;206(3):399-406. Pubmedid: 22661119. Pmcid: PMC4542577.
  • Knapp CF, Sayegh Z, Schell MJ, Rawal B, Ochoa T, Sondak VK, Messina JL. Expression of CXCR4, E-cadherin, Bcl-2, and survivin in Merkel cell carcinoma: an immunohistochemical study using a tissue microarray. Am J Dermatopathxxx. 2012 Aug;34(6):592-596. Pubmedid: 22814318. Pmcid: PMC4634647.
  • Mathew R, Messina JL. Recent advances in pathologic evaluation and reporting of melanoma. Semin Oncol. 2012 Apr;39(2):184-191. Pubmedid: 22484190.
  • Marcum CB, Zager JS, Bélongie IP, Messina JL, Fenske NA. Profound proliferating angiolymphoid hyperplasia with eosinophilia of pregnancy mimicking angiosarcoma. Cutis. 2011 Sep;88(3):122-128. Pubmedid: 22017064.
  • Viscidi RP, Rollison DE, Sondak VK, Silver B, Messina JL, Giuliano AR, Fulp W, Ajidahun A, Rivanera D. Age-specific seroprevalence of Merkel cell polyomavirus, BK virus, and JC virus. Clin Vaccine Immunol. 2011 Oct;18(10):1737-1743. Pubmedid: 21880855. Pmcid: PMC3187023.
  • Gaudi S, Messina JL. Molecular bases of cutaneous and uveal melanomas. Patholog Res Int. 2011 Nov;2011:159421. Pubmedid: 21876842. Pmcid: PMC3159309.
  • Zager JS, Rollison DE, Messina J. Prognostication in Merkel cell carcinoma. Expert Rev Anticancer Ther. 2011 May;11(5):665-667. Pubmedid: 21554038.
  • Franklin JL, Keeton AB, Bortoff KD, Messina JL. Insulin Dependant Gene Expression of Heat Shock Protein 60 in H4IIE Hepatoma Cells. Int J Clin Exp Med. 2011 Jul;1(1):89-97. Pubmedid: 19079690. Pmcid: PMC2596339.
  • Sherrill AM, Crespo G, Prakash AV, Messina JL. Desmoplastic nevus: An entity distinct from spitz nevus and blue nevus. Am J Dermatopathol. 2011 Feb;33(1):35-39. Pubmedid: 21124206.
  • Mouzakis J, Black W, Messina J, Cherpelis B. Vesiculobullous variant of adult T-cell leukemia/lymphoma in a Caribbean Émigré. J Drugs Dermatol. 2011 Dec;10(12):1469-1471. Pubmedid: 22134574.
  • Patel NS, Johnston RB, Messina JL, Cherpelis BS. A unique basaloid proliferation encountered during Mohs surgery: potential pitfall for overdiagnosis of basal cell carcinoma. Dermatol Surg. 2011 Aug;37(8):1180-1188. Pubmedid: 21668568.
  • Paraiso KH, Xiang Y, Rebecca VW, Abel EV, Chen YA, Munko AC, Wood E, Fedorenko IV, Sondak VK, Anderson AR, Ribas A, Palma MD, Nathanson KL, Koomen JM, Messina JL, Smalley KS. PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression. Cancer Res. 2011 Apr;71(7):2750-2760. Pubmedid: 21317224. Pmcid: PMC3070772.
  • Zager JS, Hochwald SN, Marzban SS, Francois R, Law KM, Davis AH, Messina JL, Vincek V, Mitchell C, Church A, Copeland EM, Sondak VK, Grobmyer SR. Shave biopsy is a safe and accurate method for the initial evaluation of melanoma. J Am Coll Surg. 2011 Apr;212(4):454-460. Pubmedid: 21463767. Pmcid: PMC4505798.
  • Chu CK, Zager JS, Marzban SS, Gimbel MI, Murray DR, Hestley AC, Messina JL, Sondak VK, Carlson GW, Delman KA. Routine biopsy of Cloquet's node is of limited value in sentinel node positive melanoma patients. J Surg Oncol. 2010 Sep;102(4):315-320. Pubmedid: 20740592.
  • Agarwala SS, di Pietro A, Flaherty KT, Garbe C, Grob JJ, Kashani-Sabet M, Kirkwood JM, Leachman S, Messina J, O'Day S, Ribas A, Sondak V. Meeting report from the Third Global Workshop on Melanoma. Pigment Cell Melanoma Res. 2010 Oct;23(5):e1-e7. Pubmedid: 20718940.
  • Casper DJ, Ross KI, Messina JL, Sondak VK, Bodden CN, McCardle TW, Frank Glass L. Useof anti-phosphohistone H3 immunohistochemistry to determine mitotic rate in thin melanoma. Am J Dermatopathol. 2010 Oct;32(7):650-654. Pubmedid: 20559123.
  • Paraiso KH, Der Kooi KV, Messina JL, Smalley KS. Measurement of constitutive MAPK and PI3K/AKT signaling activity in human cancer cell lines. Methods Enzymol. 2010 Nov;484:549-567. Pubmedid: 21036250. Pmcid: PMC4001792.
  • Messina JL, Sondak VK. Refining the criteria for sentinel lymph node biopsy in patients with thinner melanoma: a roadmap for the future. Cancer. 2010 Mar;116(6):1403-1405. Pubmedid: 20091836.
  • Paraiso KH, Fedorenko IV, Cantini LP, Munko AC, Hall M, Sondak VK, Messina JL, Flaherty KT, Smalley KS. Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy. Brit J Cancer. 2010 Jun;102(12):1724-1730. Pubmedid: 20531415. Pmcid: PMC2883709.
  • Smithberger ES, Rezania D, Chavan RN, Lien MH, Cualing HD, Messina JL. Primary cutaneous angioimmunoblastic T-cell lymphoma histologically mimicking an inflammatory dermatosis. J Drugs Dermatol. 2010 Jul;9(7):851-855. Pubmedid: 20677543.
  • Sarnaik AA, Zager JS, Cox LE, Ochoa TM, Messina JL, Sondak VK. Routine Omission of Sentinel Lymph Node Biopsy for Merkel Cell Carcinoma <= 1 cm Is Not Justified. J Clin Oncol. 2010 Jan;28(1):e7-e7. Pubmedid: 19933899.
  • Santillan AA, Messina JL, Marzban SS, Crespo G, Sondak VK, Zager JS. Pathology review of thin melanoma and melanoma in situ in a multidisciplinary melanoma clinic: impact on treatment decisions. J Clin Oncol. 2010 Jan;28(3):481-486. Pubmedid: 20008627.
  • Hamill JR, Messina JL. Merkel cell carcinoma: selected clinical cases. Curr Probl Cancer. 2010 Jan;34(1):118-123. Pubmedid: 20371079.
  • Farma JM, Ammori JB, Zager JS, Marzban SS, Bui MM, Bichakjian CK, Johnson TM, Lowe L, Sabel MS, Wong SL, Letson GD, Messina JL, Cimmino VM, Sondak VK. Dermatofibrosarcoma protuberans: how wide should we resect?. Ann Surg Oncol. 2010 Aug;17(8):2112-2118. Pubmedid: 20354798.
  • Messina J, Möller MG, Sondak VK, Glass FL, Cruse CW. The contoured staged marginal and central surgical excision technique with en face histopathological analysis: useful additions in the armamentarium for treating and diagnosing melanoma in situ. Ann Surg Oncol. 2009 Sep;16(9):2654-2655. Pubmedid: 19588203.
  • Agarwala SS, Becker JC, Eggermont AM, Flaherty KT, Garbe C, Goldstein AM, Halpern A, Kashani-Sabet M, Hauschild A, Kirkwood JM, Leachman S, Lorigan P, McMahon M, Messina J, Ribas A, Samlowski WE, Schadendorf D, Sondak VK. Meeting report: consensus from the first and second Global Workshops in Melanoma November 19-20, 2008. Pigment Cell Melanoma Res. 2009 Oct;22(5):532-543. Pubmedid: 19659612.
  • Marrero B, Messina JL, Heller R. Generation of a tumor spheroid in a microgravity environment as a 3D model of melanoma. In Vitro Cell Dev-An. 2009 Oct;45(9):523-534. Pubmedid: 19533253. Pmcid: PMC3138212.
  • Li L, Messina JL. Acute insulin resistance following injury. Trends Endocrinol Metab. 2009 Nov;20(9):429-435. Pubmedid: 19800814. Pmcid: PMC2939005.
  • Möller MG, Pappas-Politis E, Zager JS, Santiago LA, Yu D, Prakash A, Kinal A, Clark GS, Zhu W, Puleo CA, Glass LF, Messina JL, Sondak VK, Cruse CW. Surgical management of melanoma-in-situ using a staged marginal and central excision technique. Ann Surg Oncol. 2009 Jun;16(6):1526-1536. Pubmedid: 19050971.
  • Homsi J, Cubitt CL, Zhang S, Munster PN, Yu H, Sullivan DM, Jove R, Messina JL, Daud AI. Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma. Melanoma Res. 2009 Jun;19(3):167-175. Pubmedid: 19434004.
  • Phan GQ, Messina JL, Sondak VK, Zager JS. Sentinel lymph node biopsy for melanoma: indications and rationale. Cancer Control. 2009 Jul;16(3):234-239. Pubmedid: 19556963.
  • Mills O, Messina JL. Pediatric melanoma: a review. Cancer Control. 2009 Jul;16(3):225-233. Pubmedid: 19556962.
  • Li L, Thompson LH, Zhao L, Messina JL. Tissue-specific difference in the molecular mechanisms for the development of acute insulin resistance after injury. Endocrinology. 2009 Jan;150(1):24-32. Pubmedid: 18801909. Pmcid: PMC2630903.
  • McCardle TW, Messina JL, Sondak VK. Completely regressed cutaneous melanocytic lesion revisited. Semin Oncol. 2009 Dec;36(6):498-503. Pubmedid: 19995640.
  • Zager J, Bui M, Farma J, Messina J, Sondak V. Proper margins of excision in dermatofibrosarcoma protuberans: wide or narrow?. Ann Surg Oncol. 2008 Sep;15(9):2614-2616. Pubmedid: 18452044.
  • Sagatys E, Messina J, Rojiani A. 55-year-old man with a paraspinal mass. Brain Pathol. 2008 Oct;18(4):631-635. Pubmedid: 18782182.
  • Rollison D, Pawlita M, Giuliano A, Iannacone M, Sondak V, Messina J, Cruse C, Fenske N, Glass L, Kienstra M, Michael K, Waterboer T, Gheit T, Tommasino M. Measures of cutaneous human papillomavirus infection in normal tissues as biomarkers of HPV in corresponding nonmelanoma skin cancers. Int J Cancer. 2008 Nov;123(10):2337-2342. Pubmedid: 18729188.
  • Clark G, Pappas-Politis E, Cherpelis B, Messina J, Moller M, Cruse C, Glass L. Surgical management of melanoma in situ on chronically sun-damaged skin. Cancer Control. 2008 Jul;15(3):216-224. Pubmedid: 18596673.
  • Messina JL, Yu H, Riker AI, Munster PN, Jove RL, Daud AI. Activated stat-3 in melanoma. Cancer Control. 2008 Jul;15(3):196-201. Pubmedid: 18596671.
  • Fishman M, Hunter T, Soliman H, Thompson P, Dunn M, Smilee R, Farmelo M, Noyes D, Mahany J, Lee J, Cantor A, Messina J, Seigne J, Pow-Sang J, JanssenW, Antonia S. Phase II Trial of B7-1 (CD-86) Transduced, Cultured Autologous Tumor Cell Vaccine Plus Subcutaneous Interleukin-2 for Treatment of Stage IV Renal Cell Carcinoma. J Immunother (1997). 2008 Jan;31(1):72-80. Pubmedid: 18157014.
  • Daud AI, DeConti RC, Andrews S, Urbas P, Riker AI, Sondak VK, Munster PN, Sullivan DM, Ugen KE, Messina JL, Heller R. Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma. J Clin Oncol. 2008 Dec;26(36):5896-5903. Pubmedid: 19029422. Pmcid: PMC2645111.
  • Dissanayake SK, Olkhanud PB, O'Connell MP, Carter A, French AD, Camilli TC, Emeche CD, Hewitt KJ, Rosenthal DT, Leotlela PD, Wade MS, Yang SW, Brant L, Nickoloff BJ, Messina JL, Biragyn A, Hoek KS, Taub DD, Longo DL, Sondak VK, Hewitt SM, Weeraratna AT. Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer Res. 2008 Dec;68(24):10205-10214. Pubmedid: 19074888. Pmcid: PMC2605679.
  • Sondak VK, Messina JL. Lymphangiogenesis: host and tumor factors in nodal metastasis. Arch Dermatol. 2008 Apr;144(4):536-537. Pubmedid: 18427050.
  • Patrick R, Fenske N, Messina J. Primary mucosal melanoma. J Am Acad Dermatol. 2007 May;56(5):828-834. Pubmedid: 17349716.
  • Sondak V, Zager J, Messina J, Thomas J. Sentinel lymph node biopsy as the standard of care for cutaneous melanoma. Clin Adv Hematol Oncol. 2007 Jun;5(6):483-490. Pubmedid: 17679922.
  • Dessureault S, Noyes D, Lee D, Dunn M, Janssen W, Cantor A, Sotomayor E, Messina J, Antonia S. A phase-I trial using a universal GM-CSF-producing and CD40L-expressing bystander cell line (GM.CD40L) in the formulation of autologous tumor cell-based vaccines for cancer patients with stage IV disease. Ann Surg Oncol. 2007 Feb;14(2):869-884. Pubmedid: 17103257.
  • Hightower KD, Messina JL. Cutaneous protothecosis: a case report and review of the literature. Cutis. 2007 Aug;80(2):129-131. Pubmedid: 17944171.
  • Jensen EH, Lewis JM, McLoughlin JM, Alvarado MD, Daud A, Messina J, Enkemann S, Yeatman TJ, Sondak VK, Riker AI. Down-regulation of pro-apoptotic genes is an early event in the progression of malignant melanoma. Ann Surg Oncol. 2007 Apr;14(4):1416-1423. Pubmedid: 17195911.
  • Sondak V, Messina J. Current status of biomarkers for melanoma metastasis. Idrugs. 2006 Sep;9(9):627-631. Pubmedid: 16952070.
  • Baldwin B, Prakash A, Fenske N, Messina J. Aquagenic syringeal acrokeratoderma: report of a case with histologic findings. J Am Acad Dermatol. 2006 May;54(5):899-902. Pubmedid: 16635679.
  • Chang SJ, Sims J, Murtagh FR, McCaffrey JC, Messina JL. Proliferating trichilemmal cysts of the scalp on CT. Ajnr Am J Neuroradiol. 2006 Mar;27(3):712-714. Pubmedid: 16552022.
  • Puleo C, Messina J, Riker A, Glass L, Nelson C, Cruse C, Johnson T, Sondak V. Sentinel node biopsy for thin melanomas: which patients should be considered?. Cancer Control. 2005 Oct;12(4):230-235. Pubmedid: 16258494.
  • Homsi J, Kashani-Sabet M, Messina J, Daud A. Cutaneous melanoma: prognostic factors. Cancer Control. 2005 Oct;12(4):223-229. Pubmedid: 16258493.
  • Riker A, Glass F, Perez I, Cruse C, Messina J, Sondak V. Cutaneous melanoma: methods of biopsy and definitive surgical excision. Dermatol Ther. 2005 Oct;18(5):387-393. Pubmedid: 16297013.
  • Munn DH, Sharma MD, Hou D, Baban B, Lee JR, Antonia SJ, Messina JL, Chandler P, Koni PA, Mellor AL. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest. 2004 Jul;114(2):280-290. Pubmedid: 15254595. Pmcid: PMC449750.
  • Bickle K, Glass L, Messina J, Fenske N, Siegrist K. Merkel cell carcinoma: a clinical, histopathologic, and immunohistochemical review. Semin Cutan Med Surg. 2004;23(1):46-53. Pubmedid: 15095915.
  • Naing A, Messina J, Vrionis F, Daud A. Uncommon manifestations of common malignancies: case 3. Malignant melanoma arising from a spinal nerve root. J Clin Oncol. 2004;22(15):3194-3195. Pubmedid: 15284274.
  • Lee JR, Dalton RR, Messina JL, Sharma MD, Smith DM, Burgess RE, Mazzella F, Antonia SJ, Mellor AL, Munn DH. Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma. Lab Invest. 2003 Oct;83(10):1457-1466. Pubmedid: 14563947.
  • Reschly M, Messina J, Zaulyanov L, Cruse W, Fenske N. Utility of sentinel lymphadenectomy in the management of patients with high-risk cutaneous squamous cell carcinoma. Dermatol Surg. 2003;29(2):135-140. Pubmedid: 12562341.
  • Fairbee S, Fenske N, Messina J, Hogan D, Castellano-Howard L. Extrafacial granuloma faciale: report of a case and response to treatment. Cutis. 2001 May;67(5):413-415. Pubmedid: 11381859.
  • Shivers S, Li W, Stall A, Stafford M, Messina J, Glass L, Reintgen D. The clinical relevance of molecular staging for melanoma. Recent Results Cancer Res. 2001;158:187-199. Pubmedid: 11092046.
  • Cherpelis B, Haddad F, Messina J, Cantor A, Fitzmorris K, Reintgen D, Fenske N, Glass L. Sentinel lymph node micrometastasis and other histologic factors that predict outcome in patients with thicker melanomas. J Am Acad Dermatol. 2001;44(5):762-766. Pubmedid: 11312421.
  • Frank SJ, Messina JL, Baumann G, Black RA, Bertics PJ. Insights into modulation of (and by) growth hormone signaling. J Lab Clin Med. 2000 Jul;136(1):14-20. Pubmedid: 10882223.
  • Smith D, Messina J, Perrott R, Berman C, Reintgen D, Cruse C, Glass F, DeConti R, Trotti A, Fenske N. Clinical approach to neuroendocrine carcinoma of the skin (Merkel cell carcinoma). Cancer Control. 2000;7(1):72-83. Pubmedid: 10740663.
  • Byrd-Gloster A, Khoor A, Glass L, Messina J, Whitsett J, LivingstonSK, Cagle P. Differential expression of thyroid transcription factor 1 in small cell lung carcinoma and Merkel cell tumor. Hum Pathol. 2000;31(1):58-62. Pubmedid: 10665914.
  • Li W, Stall A, Shivers S, Lin J, Haddad F, Messina J, Glass F, Lyman G, Reintgen D. Clinical relevance of molecular staging for melanoma: comparison of RT-PCR and immunohistochemistry staining in sentinel lymph nodes of patients with melanoma. Ann Surg. 2000;231(6):795-803. Pubmedid: 10816622.
  • Pu LL, Cruse CW, Wells KE, Cantor A, Glass LF, Messina JL, Reintgen DS. Lymphatic mapping and sentinel lymph node biopsy in patients with melanoma of the lower extremity. Plast Reconstr Surg. 1999 Sep;104(4):964-969. Pubmedid: 10654734.
  • Haddad FF, Stall A, Messina J, Brobeil A, Ramnath E, Glass LF, Cruse CW, Berman CG, Reintgen DS. The progression of melanoma nodal metastasis is dependent on tumor thickness of the primary lesion. Ann Surg Oncol. 1999 Mar;6(2):144-149. Pubmedid: 10082038.
  • Messina J, Glass L, Cruse C, Berman C, Ku N, Reintgen D. Pathologic examination of the sentinel lymph node in malignant melanoma. Am J Surg. 1999 Jun;23(6):686-690. Pubmedid: 10366151.
  • Kamath D, Milotes G, Lyman G, Rapaport D, Cruse C, Glass F, Fenske N, Messina J, Berman C, Reintgen D. Cutaneous lymphatic drainage in patients with grossly involved nodal basins. Ann Surg Oncol. 1999 Jun;6(4):345-349. Pubmedid: 10379854.
  • Brobeil A, Cruse CW, Messina JL, Glass LF, Haddad FF, Berman CG, Marshburn J, Reintgen DS. Cost analysis of sentinel lymph node biopsy as an alternative to elective lymph node dissection in patients with malignant melanoma. Surg Oncol Clin N Am. 1999 Jul;8(3):435-45, viii. Pubmedid: 10448688.
  • Goscin C, Glass LF, Messina JL. Pathologic examination of the sentinel lymph node in melanoma. Surg Oncol Clin N Am. 1999 Jul;8(3):427-34, viii. Pubmedid: 10448687.
  • Shivers S, Wang X, Li W, Joseph E, Messina J, Glass L, DeConti R, Cruse W, Berman C, Fenske N, Lyman G, Reintgen D. Molecular staging of malignant melanoma: correlation with clinical outcome. Jama. 1998 Oct;280(16):1410-1415. Pubmedid: 9801000.
  • Joseph E, Glass F, Glass J, Messina J, DeConti R, Cruse C, Rapaport D, Berman C, Fenske N, Reintgen D. Results of complete lymph node dissection in 83 melanoma patients with positive sentinel nodes. Ann Surg Oncol. 1998 Mar;5(2):119-125. Pubmedid: 9527264.
  • Glass L, Keller K, Messina J, Dalton J, Yag-Howard C, Fenske N. Cutaneous T-cell lymphoma. Cancer Control. 1998 Jan;5(1):11-18. Pubmedid: 10761012.
  • Reks SE, Smith PH, Messina JL, Weinstock RS. Translocation of PKC delta by insulin in a rat hepatoma cell line. Endocrine. 1998 Apr;8(2):161-167. Pubmedid: 9704573.
  • Reintgen D, Haddad F, Pendas S, Berman C, Ku N, Glass F, Messina J, Cox C. Sentinel node biopsy in ductal carcinoma in situ patients. Scientific America Surgery. 1998;12(9):1283-1292. Pubmedid: noPMID.
  • Brobeil A, Kamath D, Cruse CW, Rapaport DP, Wells KE, Shons AR, Messina JL, Glass LF, Berman CG, Puleo CA, Reintgen DS. The clinical relevance of sentinel lymph nodes identified with radiolymphoscintigraphy. J Fla Med Assoc. 1997 Mar;84(3):157-160. Pubmedid: 9143166.
  • Kamath D, Rapaport D, DeConti R, Cruse C, Wells K, Glass L, Messina J, Fenske N, Brobeil A, Berman C, Puleo C, Reintgen D. Redefining cutaneous lymphatic flow: the necessity of preoperative lymphoscintigraphy in the management of malignant melanoma. J Fla Med Assoc. 1997 Mar;84(3):182-187. Pubmedid: 9143170.
  • Messina JL, Glass LF. Pathologic examination of the sentinel lymph node. J Fla Med Assoc. 1997 Mar;84(3):153-156. Pubmedid: 9143165.
  • Ramnath E, Kamath D, Brobeil A, Stall A, Kamath V, Cruse C, Glass F, Messina J, Fenske N, Berman C, Cantor A, Cuthbertson D, Reintgen D, Ross M. Lymphatic mapping for melanoma: long-term results of regional nodal sampling with radioguided surgery. Cancer Control. 1997;4:483-490. Pubmedid: 10763056.
  • Kamath D, Cantor A, Glass L, Fenske N, Cruse C, Wells K, Rapaport D, DeConti R, Messina J, Reintgen D. Florida's undeclared epidemic: malignant melanoma. J Fla Med Assoc. 1997;84(3):161-165. Pubmedid: 9143167.
  • Brobeil A, Rapaport D, Wells K, Cruse C, Glass F, Fenske N, Albertini J, Miliotis G, Messina J, DeConti R, Berman C, Shons A, Cantor A, Reintgen D. Multiple primary melanomas: implications for screening and follow-up programs. Ann Surg Oncol. 1997;4:19-23. Pubmedid: 8985513.
  • Le A, Fenske N, Glass L, Messina J. Malignant melanoma: differential diagnosis of pigmented lesions. J Fla Med Assoc. 1997;84(3):166-174. Pubmedid: 9143168.
  • Cruse C, Reintgen D, Glass F, Messina J, Trotti, III A, DeConti R. Clinical practice guidelines: neuroendocrine tumors of the skin. Cancer Control. 1997;4:258-260. Pubmedid: noPMID.
  • Heller R, Jaroszeski M, Perrott R, Messina J, Gilbert R. Effective treatment of B16 melanoma by direct delivery of bleomycin using electrochemotherapy. Melanoma Res. 1997;7:10-18. Pubmedid: 9067960.
  • Joseph E, Lyman G, Messina J. Tumor markers in malignant melanoma: a review. Tumor Marker Update. 1997;9:157-163. Pubmedid: noPMID.
  • Heller R, Jaroszeski M, Glass L, Messina J, Rapaport D, DeConti R, Fenske N, Gilbert R, Mir L, Reintgen D. Phase I/II trial for the treatment of cutaneous and subcutaneous tumors using electrochemotherapy. Cancer. 1996 Mar;77(5):964-971. Pubmedid: 8608491 .
  • Glass LF, Fotopoulos T, Messina J. A generalized cutaneous reaction induced by granulocyte colony-stimulating factor. J Am Acad Derm. 1996 Mar;34(3):455-459. Pubmedid: 8609259.
  • Albertini J, Cruse C, Rapaport D, Wells K, DeConti R, Berman C, Jared K, Messina J, Lyman G, Glass L, Fenske N, Reintgen D. Intraoperative radio-lympho-scintigraphy improves sentinel lymph node identification for patients with melanoma. Ann Surg. 1996 Feb;223(2):217-224. Pubmedid: 8597518. Pmcid: PMC1235100.
  • Glass LF, Messina JL, Cruse W, Wells K, Rapaport D, Miliotes G, Berman C, Reintgen D, Fenske NA. The use of intraoperative radiolymphoscintigraphy for sentinel node biopsy in patients with malignant melanoma. Dermatol Surg. 1996 Aug;22(8):715-720. Pubmedid: 8780765.
  • Meliotis G, Albertini J, Berman C, Heller R, Messina J, Glass L, Cruse C, Rapaport D, Puleo C, Fenske N, Petsofglov C, DeConti R, Lyman G. The tumor biology of melanoma nodal metastasis. Am Surg. 1996;62:81-88. Pubmedid: 8540654.
  • Glass L, Fenske N, Messina J, Cruse C, Rapaport D, Berman C, Puleo C, Heller R, Miliotes G, Albertini J, Reintgen D. The role of selective lymphadenectomy in the management of patients with malignant melanomoa. Dermatol Surg. 1996;21:979-983.
  • Heller R, Jaroszeski M, Glass L, Messina J, Rapaport D, DeConti R, Fenske N, Gilbert R, Mir L, Reintgen D. Phase I/II trial of cutaneous and subcutaneous malignancies using electrochemotherapy. Cancer. 1996;75(5):964-971. Pubmedid: 8608491.
  • Messina J, Yag-Howard C, Fenske N. Cutaneous hyperpigmentation due to quinine gluconate. J Geriatr Dermatol. 1996;4(6):198-201.
  • Glass LF, Fenske NA, Messina JL, Cruse CW, Rapaport DP, Berman C, Puleo CA, Heller R, Miliotes G, Albertini J. The role of selective lymphadenectomy in the management of patients with malignant melanoma. Dermatol Surg. 1995 Nov;21(11):979-983. Pubmedid: 7582838.
  • Godellas CV, Berman CG, Lyman G, Cruse CW, Rapaport D, Heller R, Wang X, Glass F, Fenske N, Messina J, et a. The identification and mapping of melanoma regional nodal metastases: minimally invasive surgery for the diagnosis of nodal metastases. Am Surg. 1995 Feb;61(2):97-101. Pubmedid: 7856986 .
  • Godellas CV, Berman CG, Lyman G, Cruse CW, Rapaport D, Heller R, Wang X, Glass F, Fenske N, Messina J. The identification and mapping of melanoma regional nodal metastases: minimally invasive surgery for the diagnosis of nodal metastases. Am Surg. 1995 Feb;61(2):97-101. Pubmedid: 7856986.
  • Reintgen D, Albertini J, Berman C, Cruse C, Fenske N, Glass L, Puleo C, Wang X, Wells K, Rapaport D, DeConti R, Messina J, Heller R. Accurate nodal staging of malignant melanoma. Cancer Control. 1995;2(5):405-414. Pubmedid: 10862181.
  • Stadelmann W, Cruse C, Messina J. Synovial cell sarcoma of the temporomandibular joint. Ann Plast Surg. 1995;35(6):664-668. Pubmedid: 8748354.
  • Vesper J, Messina J, Glass L, Fenske N. Profound proliferating pearly penile papules. Int J Dermatol. 1995;34:425-426. Pubmedid: 7657443.
  • Norman Jr. J, Franz M, Fink G, Messina J, Fabri P, Gower W, Carey L. Decreased mortality of severe acute pancreatitis after proximal cytokine blockade. Ann Surg. 1995;221(6):625-634. Pubmedid: 7794067.
  • Heller R, Jaroszeski M, Messina J, Perrot R, VanVoorhis N, Reintgen D, Gilbert R. Treatment of B16 mouse melanoma with the combination of electropermeabilization and chemotherapy. Bioelectrochem Bioenerg. 1995;36:83-87. Pubmedid: noPMID.
  • Reintgen D, Albertini J, Miliotes G, Berman C, Cruse C, Fenske N, Glasser S, Puleo C, Wang X, Wells K, Rapaport D, DeConti R, Messina J, Heller R. The accurate staging and modern day treatment of malignant melanoma. Cancer Res Ther Cont. 1995;4:183-197. Pubmedid: noPMID.
  • Norman Jr. J, Franz J, Messina J, Riker A, Fabri P, Rosemurgy II A, Gower W. Interleukin-1 receptor anagonist decreases severity of experimental acute pancreatitis. Surgery. 1995;117:648-655. Pubmedid: 7539942.
  • Norma J, Messina J, Franz M, Fabri P, Gower W. Hodgkin's disease masquerading as Sclerosing Mediastinitis. South Med J. 1994;106:310-311.
  • Norman Jr. J, Messina J, Franz M, Fabri P, Gower W. Decreased severity of experimental acute pancreatitis by pre or post treatment with interleukin-1 receptor antagonist. Gastroenterology. 1994;106:310-311.
  • Flannery M, Espino M, Altus P, Messina J, Wallach P. Hodgkin's disease masquerading as sclerosing mediastinitis. South Med J. 1994;87:921-923.
  • Messina J, Ishizuka T, Weinstock R, Standaert M, Farese R. Role of protein kinase C in insulin's regulation of c-fos transcription. J Biol Chem. 1992;267:9223-9228.
  • Messina J, Reintgen D, Cruse C, Rapaport D, Berman C, Fenske N, Glass L. Selective lymphadenectomy in patients with Merkel cell (cutaneous neuroendocrine) carcinoma. Ann Surg Oncol. 4(5):389-395. Pubmedid: 9259965.
  • McCardle TW, Sondak VK, Zager J, Messina JL. Merkel cell carcinoma: pathologic findings and prognostic factors. Curr Prob Cancer. 34(1):47-64. Pubmedid: 20371074.
  • Joseph E, Messina J, Glass FL, Cruse CW, Rapaport DP, Berman C, Greenberg H, Reintgen DS. Radioguided surgery for the ultrastaging of the patient with melanoma. Cancer J Sci Am. 3(6):341-345. Pubmedid: 9403046.