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Tapan A. Padhya, MD


Specialty: Otolaryngology
Program: Head and Neck-Endocrine Oncology

Call 1-888-MOFFITT
(1-888-663-3488)

or call 1-888-MOFFITT
(1-888-663-3488)

Overview

Health disparities in oral cancer. Thyroid and parathyroid tumors, skull base oncology

Education & Training

Board Certification:

  • Otolaryngology

Fellowship:

  • University of Cincinnati Medical Center - Advanced Head & Neck\Skull Base Oncology

Residency:

  • University of Louisville School of Medicine - Otolaryngology

Medical School:

  • Indiana University School of Medicine - MD
Participating Trials

CLINICAL TRIAL 17716
A Biomarker-related Approach to Screening for HPV-related Oropharyngeal Cancer
Condition: Head & Neck
Intervention:
Open

CLINICAL TRIAL 17799
A Phase I Dose Escalation Trial of Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of the Head and Neck
Condition: Head & Neck
Intervention: cisplatin
Open

CLINICAL TRIAL 18612
A Randomized Phase II/III Study of Adjuvant Concurrent Radiation and Chemotherapy versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors
Condition: Head & Neck
Intervention: cisplatin
Open

CLINICAL TRIAL 18789
A Randomized Phase 2 Trial of Neoadjuvant and Adjuvant Therapy with the IRX-2 Regimen in Patients with Newly Diagnosed Stage II, III or IVA Squamous Cell Carcinoma of the Oral Cavity
Condition: Head & Neck
Intervention: IRX-2; Indomethacin; cyclophosphamide; cytoxan (cyclophosphamide); multivitamin/mineral; omeprazole (Prilosec)
Open

If you believe you are eligible for one of these trials or studies, please call
1-888-MOFFITT (1-888-663-3488).

Publications

  • Basler K, Malone A, Carmichael M, Hafez O, Padhya T, Boyev KP. Spontaneous Otorrhagia after Laparoscopic Pelvic Surgery: A Report of Two Cases. J Int Adv Otol. 2017 Nov. Pubmedid: 29092805.
  • Wang HL, Liu CJ, Kilpatrick M, Jim H, McMillan S, Vijayakumar N, McDonald S, Padhya T, Russell J, Vondruska K, Visovsky C. Exergame Grading Scheme: Concept Development and Preliminary Psychometric Evaluations in Cancer Survivors. Rehabil Res Pract. 2017 Nov;2017:6843016. Pubmedid: 29098087. Pmcid: PMC5643152.
  • Arnaoutakis D, Padhya T. Zika Virus-What the Otolaryngologist Should Know: A Review. JAMA Otolaryngol Head Neck Surg. 2017 Jan;143(1):81-84. Pubmedid: 27892990.
  • Strom T, Naghavi AO, Messina JL, Kim S, Torres-Roca JF, Russell J, Sondak VK, Padhya TA, Trotti AM, Caudell JJ, Harrison LB. Improved local and regional control with radiotherapy for Merkel cell carcinoma of the head and neck. Head Neck. 2017 Jan;39(1):48-55. Pubmedid: 27300153.
  • Gillespie MB, Soose RJ, Woodson BT, Strohl KP, Maurer JT, de Vries N, Steward DL, Baskin JZ, Badr MS, Lin HS, Padhya TA, Mickelson S, Anderson WM, Vanderveken OM, Strollo PJ. Upper Airway Stimulation for Obstructive Sleep Apnea: Patient-Reported Outcomes after 48 Months of Follow-up. Otolaryngol Head Neck Surg. 2017 Apr;156(4):765-771. Pubmedid: 28194999.
  • Valderrabano P, Montilla Soler J, Mifsud MJ, Leon ME, Centeno BA, Khazai L, Padhya T, McCaffrey TV, Russell JS, McIver B, Otto KJ. Hypermetabolism on (18)F-Fluorodeoxyglucose Positron Emission Tomography Scan Does Not Influence the Interpretation of Thyroid Cytopathology, and Nodules with a SUVmax <2.5 Are Not at Increased Risk for Malignancy. Thyroid. 2016 Sep;26(9):1300-1307. Pubmedid: 27324615.
  • Wang HL, Ji M, Visovsky C, Rodriguez CS, Elliott AF, Gwede CK, Padhya TA, Ridley MB, McMillan SC. Clinically Relevant Four-Level Cancer-Related Fatigue Among Patients With Various Types of Cancer. J Adv Pract Oncol. 2016 Oct;7(1):23-37. Pubmedid: 27713842. Pmcid: PMC5045276.
  • Strom T, Carr M, Zager JS, Naghavi A, Smith FO, Cruse CW, Messina JL, Russell J, Rao NG, Fulp W, Kim S, Torres-Roca JF, Padhya TA, Sondak VK, Trotti AM, Harrison LB, Caudell JJ. Radiation Therapy is Associated with Improved Outcomes in Merkel Cell Carcinoma. Ann Surg Oncol. 2016 Oct;23(11):3572-3578. Pubmedid: 27251134.
  • Mifsud MJ, Tanvetyanon T, Mccaffrey JC, Otto KJ, Padhya TA, Kish J, Trotti AM, Harrison LB, Caudell JJ. Adjuvant radiotherapy versus concurrent chemoradiotherapy for the management of high-risk salivary gland carcinomas. Head Neck. 2016 Nov;38(11):1628-1633. Pubmedid: 27098984.
  • Dodd VJ, Schenck DP, Chaney EH, Padhya T. Assessing Oral Cancer Awareness Among Rural Latino Migrant Workers. J Immigr Minor Health. 2016 Jun;18(3):552-560. Pubmedid: 26018959.
  • Mifsud M, Sharma S, Leon M, Padhya T, Otto K, Caudell J. Salivary Duct Carcinoma of the Parotid: Outcomes with a Contemporary Multidisciplinary Treatment Approach. Otolaryngol Head Neck Surg. 2016 Jun;154(6):1041-1046. Pubmedid: 26980918.
  • Tanvetyanon T, Fisher K, Caudell J, Otto K, Padhya T, Trotti A. Adjuvant chemoradiotherapy versus with radiotherapy alone for locally advanced salivary gland carcinoma among older patients. Head Neck. 2016 Jun;38(6):863-870. Pubmedid: 26340707.
  • Mifsud MJ, Burton JN, Trotti AM, Padhya TA. Multidisciplinary Management of Salivary Gland Cancers. Cancer Control. 2016 Jul;23(3):242-248. Pubmedid: 27556664.
  • Woodson BT, Soose RJ, Gillespie MB, Strohl KP, Maurer JT, de Vries N, Steward DL, Baskin JZ, Badr MS, Lin HS, Padhya TA, Mickelson S, Anderson WM, Vanderveken OM, Strollo PJ. Three-Year Outcomes of Cranial Nerve Stimulation for Obstructive Sleep Apnea: The STAR Trial. Otolaryngol Head Neck Surg. 2016 Jan;154(1):181-188. Pubmedid: 26577774.
  • Frakes JM, Naghavi AO, Demetriou SK, Strom TJ, Russell JS, Kish JA, McCaffrey JC, Otto KJ, Padhya TA, Harrison LB, Trotti AM, Caudell JJ. Determining optimal follow-up in the management of human papillomavirus-positive oropharyngeal cancer. Cancer. 2016 Feb;122(4):634-641. Pubmedid: 26565997.
  • Frakes JM, Strom TJ, Naghavi AO, Trotti A, Rao NG, McCaffrey JC, Otto KJ, Padhya T, Caudell JJ. Outcomes of mucosal melanoma of the head and neck. J Med Imaging Radiat Oncol. 2016 Apr;60(2):268-273. Pubmedid: 26597431.
  • Smith FO, Yue B, Marzban SS, Walls BL, Carr M, Jackson RS, Puleo CA, Padhya T, Cruse CW, Gonzalez RJ, Sarnaik AA, Schell MJ, DeConti RC, Messina JL, Sondak VK, Zager JS. Both tumor depth and diameter are predictive of sentinel lymph node status and survival in Merkel cell carcinoma. Cancer. 2015 Sep;121(18):3252-3260. Pubmedid: 26038193. Pmcid: PMC4904725.
  • Tanvetyanon T, Padhya T, McCaffrey J, Kish JA, Deconti RC, Trotti A, Rao NG. Postoperative concurrent chemotherapy and radiotherapy for high-risk cutaneous squamous cell carcinoma of the head and neck. Head Neck. 2015 Jun;37(6):840-845. Pubmedid: 24623654.
  • Burton J, Wong R, Padhya T. Robotic-Assisted Surgery in the Head and Neck. Cancer Control. 2015 Jul;22(3):331-334. Pubmedid: 26351889.
  • Strom TJ, Trotti AM, Kish J, Russell JS, Rao NG, McCaffrey J, Padhya TA, Otto KJ, Caudell JJ. Comparison of every 3 week cisplatin or weekly cetuximab with concurrent radiotherapy for locally advanced head and neck cancer. Oral Oncol. 2015 Jul;51(7):704-708. Pubmedid: 25936651.
  • Ching YH, Karlnoski RA, Chen H, Camporesi EM, Shah VV, Padhya TA, Mangar D. Lingual traction to facilitate fiber-optic intubation of difficult airways: a single-anesthesiologist randomized trial. J Anesth. 2015 Apr;29(2):263-268. Pubmedid: 25249430.
  • Harrell PT, Simmons VN, Correa JB, Padhya TA, Brandon TH. Electronic nicotine delivery systems ("e-cigarettes"): review of safety and smoking cessation efficacy. Otolaryngol Head Neck Surg. 2014 Sep;151(3):381-393. Pubmedid: 24898072. Pmcid: PMC4376316.
  • Woodson BT, Gillespie MB, Soose RJ, Maurer JT, de Vries N, Steward DL, Baskin JZ, Padhya TA, Lin HS, Mickelson S, Badr SM, Strohl KP, Strollo PJ. Randomized Controlled Withdrawal Study of Upper Airway Stimulation on OSA: Short- and Long-term Effect. Otolaryngol Head Neck Surg. 2014 Sep. Pubmedid: 25205641.
  • Mifsud M, Padhya TA. Metastatic melanoma to the upper aerodigestive tract: a systematic review of the literature. Laryngoscope. 2014 May;124(5):1143-1149. Pubmedid: 24115042.
  • Perez MC, Padhya TA, Messina JL, Jackson RS, Gonzalez RJ, Bui MM, Letson GD, Cruse CW, Lavey RS, Cheong D, Forster MR, Fulp WJ, Sondak VK, Zager JS. Cutaneous angiosarcoma: a single-institution experience. Ann Surg Oncol. 2013 Oct;20(11):3391-3397. Pubmedid: 23835652. Pmcid: PMC4509495.
  • Patel SN, Sauvageau E, Padhya TA. Rare treatment of radiation induced carotid pseudoaneurysm and ensuing carotid blowout syndrome with placement of multiple contiguous endovascular stents: a case report. Am J Otolaryngol. 2013 Oct;34(3):219-222. Pubmedid: 23332404.
  • Jackson RS, May JT, Norman J, Padhya TA. Transoral carbon dioxide laser excision of an ectopic parathyroid adenoma from the hypopharynx. Otolaryngol Head Neck Surg. 2013 Nov;149(5):789-790. Pubmedid: 23921498.
  • Strom T, Trotti AM, Kish J, Rao NG, McCaffrey J, Padhya TA, Lin HY, Fulp W, Caudell JJ. Risk factors for percutaneous endoscopic gastrostomy tube placement during chemoradiotherapy for oropharyngeal cancer. JAMA Otolaryngol Head Neck Surg. 2013 Nov;139(11):1242-1246. Pubmedid: 24136493.
  • Schussel JL, Zhou XC, Zhang Z, Pattani KM, Bermudez F, Jean-Charles G, McCaffrey TV, Padhya T, Phelan J, Spivakovsky S, Brait M, Li RJ, Bowne HY, Goldberg JD, Rolnitzky L, Robbins M, Kerr AR, Sirois D, Califano JA. EDNRB and DCC salivary rinse hypermethylation has a similar performance as expert clinical examination in discrimination of oral cancer/dysplasia versus benign lesions. Clin Cancer Res. 2013 Jun;19(12):3268-3275. Pubmedid: 23637120. Pmcid: PMC3687013.
  • Arnaoutakis D, Padhya TA. Dengue fever: A primer for the otolaryngologist. Ear Nose Throat J. 2013 Jul;92(7):E5-E9. Pubmedid: 23904319.
  • May JT, Rao N, Sabater RD, Boutrid H, Caudell JJ, Merchant F, Han G, Padhya TA, McCaffrey JC, Tanvetyanon T, Deconti R, Kish J, McCaffrey TV, Trotti A. Intensity-modulated radiation therapy as primary treatment for oropharyngeal squamous cell carcinoma. Head Neck. 2013 Dec;35(12):1796-1800. Pubmedid: 23468387.
  • May JT, Padhya TA, McCaffrey TV. Endoscopic repair of Zenker's diverticulum by harmonic scalpel. Am J Otolaryngol. 2012 Mar;32(6):553-556. Pubmedid: 21306794.
  • Boyce HW, Estores DS, Gaziano J, Padhya T, Runk J. Endoscopic lumen restoration for obstructive aphagia: outcomes of a 25-year experience. Gastrointest Endosc. 2012 Jul;76(1):25-31. Pubmedid: 22482914.
  • Jackson RS, Phommachanh V, Keeler JA, Pechter W, Greene JN, Padhya T, Tabor MH. Rhinosinusitis in the Immunocompromised Cancer Population. Otolaryngol Head Neck Surg. 2012 Aug;147(2 suppl):P254-P255. Pubmedid: 25718906.
  • May JT, Newman JG, Padhya TA. Transoral robot-assisted excision of a lingual thyroid gland. J Robot Surg. 2011 Sep;5(3):217-220. Pubmedid: 27637711.
  • Burkett CJ, Patel S, Tabor MH, Padhya T, Vale FL. Polyethylene glycol (PEG) hydrogel dural sealant and collagen dural graft matrix in transsphenoidal pituitary surgery for prevention of postoperative cerebrospinal fluid leaks. J Clin Neurosci. 2011 Nov;18(11):1513-1517. Pubmedid: 21868232.
  • Patel SN, Youssef AS, Vale FL, Padhya TA. Re-evaluation of the role of image guidance in minimally invasive pituitary surgery: benefits and outcomes. Comput Aided Surg. 2011 Jun;16(2):47-53. Pubmedid: 21291344.
  • Pattani KM, Zhang Z, Demokan S, Glazer C, Loyo M, Goodman S, Sidransky D, Bermudez F, Jean-Charles G, McCaffrey T, Padhya T, Phelan J, Spivakovsky S, Bowne HY, Goldberg JD, Rolnitzky L, Robbins M, Kerr AR, Sirois D, Califano JA. Endothelin receptor type B gene promoter hypermethylation in salivary rinses is independently associated with risk of oral cavity cancer and premalignancy. Cancer Prev Res (Phila). 2010 Sep;3(9):1093-1103. Pubmedid: 20798208. Pmcid: PMC2945229.
  • Corzo CA, Condamine T, Lu L, Cotter MJ, Youn JI, Cheng P, Cho HI, Celis E, Quiceno DG, Padhya T, McCaffrey TV, McCaffrey JC, Gabrilovich DI. HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J Exp Med. 2010 Oct;207(11):2439-2453. Pubmedid: 20876310. Pmcid: PMC2964584.
  • Gwede CK, Menard JM, Martinez-Tyson D, Lee JH, Vadaparampil ST, Padhya TA, Meade CD. Strategies for assessing community challenges and strengths for cancer disparities participatory research and outreach. Health Promot Pract. 2010 Nov;11(6):876-887. Pubmedid: 19515858. Pmcid: PMC2888920.
  • Phommachanh V, Patil YJ, McCaffrey TV, Vale F, Freeman TB, Padhya TA. Otolaryngologic management of delayed pharyngoesophageal perforation following anterior cervical spine surgery. Laryngoscope. 2010 May;120(5):930-936. Pubmedid: 20422686.
  • Rogers J, Patil Y, Strickland-Marmol L, Padhya T. Lipomatous tumors of the parapharyngeal space: case series and literature review. Arch Otolaryngol Head Neck Surg. 2010 Jun;136(6):621-624. Pubmedid: 20566915.
  • Gonzalez RJ, Padhya TA, Cherpelis BS, Prince MD, Aya-Ay ML, Sondak VK, Cruse CW, Zager JS. The surgical management of primary and metastatic Merkel cell carcinoma. Curr Probl Cancer. 2010 Jan;34(1):77-96. Pubmedid: 20371076.
  • Herber DL, Cao W, Nefedova Y, Novitskiy SV, Nagaraj S, Tyurin VA, Corzo A, Cho HI, Celis E, Lennox B, Knight SC, Padhya T, McCaffrey TV, McCaffrey JC, Antonia S, Fishman M, Ferris RL, Kagan VE, Gabrilovich DI. Lipid accumulation and dendritic cell dysfunction in cancer. Nat Med. 2010 Aug;16(8):880-886. Pubmedid: 20622859. Pmcid: PMC2917488.
  • Dakwar E, Uribe JS, Padhya TA, Vale FL. Management of delayed esophageal perforations after anterior cervical spinal surgery. J Neurosurg Spine. 2009 Sep;11(3):320-325. Pubmedid: 19769513.
  • Corzo CA, Cotter MJ, Cheng P, Cheng F, Kusmartsev S, Sotomayor E, Padhya T, McCaffrey TV, McCaffrey JC, Gabrilovich DI. Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells. J Immunol. 2009 May;182(9):5693-5701. Pubmedid: 19380816. Pmcid: PMC2833019.
  • Tanvetyanon T, Qin D, Padhya T, McCaffrey J, Zhu W, Boulware D, DeConti R, Trotti A. Outcomes of postoperative concurrent chemoradiotherapy for locally advanced major salivary gland carcinoma. Arch Otolaryngol Head Neck Surg. 2009 Jul;135(7):687-692. Pubmedid: 19620591.
  • Tanvetyanon T, Qin D, Padhya T, Kapoor R, McCaffrey J, Trotti A. Survival outcomes of squamous cell carcinoma arising from sinonasal inverted papilloma: report of 6 cases with systematic review and pooled analysis. Am J Otolaryngol. 2009 Jan;30(1):38-43. Pubmedid: 19027511.
  • Tanvetyanon T, Padhya T, McCaffrey J, Zhu W, Boulware D, Deconti R, Trotti A. Prognostic Factors for Survival After Salvage Reirradiation of Head and Neck Cancer. J Clin Oncol. 2009 Apr;27(12):1983-1991. Pubmedid: 19289616.
  • Vale F, Padhya T, Youssef A, Morgan J. Penetrating craniofacial injury inflicted by a knife. J Trauma. 2008 Jun;64(6):1622-1624. Pubmedid: 16983297.
  • Fanarjian N, Athavale S, Herrero N, Fiorica J, Padhya T. Thyroid cancer in pregnancy. Laryngoscope. 2007 Oct;117(10):1777-1781. Pubmedid: 17690608.
  • Padhya T, Cornelius R, Athavale S, Gluckman J. Perineural extension to the skull base from early cutaneous malignancies of the midface. Otolaryngol Head Neck Surg. 2007 Nov;137(5):742-746. Pubmedid: 17967638.
  • Padhya T, Athavale S, Kathju S, Sarkar S, Mehta A. Osteochondroma of the skull base. Otolaryngol Head Neck Surg. 2007 Jul;137(1):166-168. Pubmedid: 17599588.
  • Powell S, Nguyen C, Gaziano J, Lewis V, Lockey R, Padhya T. Mass psychogenic illness presenting as acute stridor in an adolescent female cohort. Ann Otol Rhinol Laryngol. 2007 Jul;116(7):525-531. Pubmedid: 17727084.
  • Kienstra M, Padhya T. Head and neck melanoma. Cancer Control. 2005 Oct;12(4):242-247. Pubmedid: 16258496.
  • Vrionis F, Kienstra M, Rivera M, Padhya T. Malignant tumors of the anterior skull base. Cancer Control. 2004 May;11(3):144-151. Pubmedid: 15153838.
  • Rivera M, Padhya T. Acanthamoeba: a rare primary cause of rhinosinusitis. Laryngoscope. 2002 Jul;112(7 Pt 1):1201-1203. Pubmedid: 12169899.
  • Bumpous J, Padhya T, Barnett S. Basal cell carcinoma of the head and neck: identification of predictors of recurrence. Ear Nose Throat J. 2000 Mar;79(3):200-2, 204. Pubmedid: 10743767.
  • Bejarano P, Padhya T, Smith R, Blough R, Devitt J, Gluckman J. Hyalinizing spindle cell tumor with giant rosettes--a soft tissue tumor with mesenchymal and neuroendocrine features. An immunohistochemical, ultrastructural, and cytogenetic analysis. Arch Pathol Lab Med. 2000 Aug;124(8):1179-1184. Pubmedid: 10923080.
  • Ganzel T, Goldman J, Padhya T. Otolaryngologic clinical patterns in pediatric infectious mononucleosis. Am J Otolaryngol. 1996 Nov;17(6):397-400. Pubmedid: 8944299 .
  • Scott BA, Padhya TA. Composite grafts from the ear.. In: Bailey B, ed. Atlas of Head & Neck Surgery-Otolaryngology. Philadelphia, PA: Lippincott-Raven; 1994;668-669.