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M. Catherine Lee, MD, FACS


Specialty: Surgery
Program: Breast Oncology

Call 1-888-MOFFITT
(1-888-663-3488)

or call 1-888-MOFFITT
(1-888-663-3488)

Overview

Dr. Marie Catherine Lee graduated magna cum laude from Kent State University and completed her MD degree at the Northeast Ohio University College of Medicine in Rootstown, Ohio.  After a general surgery residency at Lenox Hill Hospital in New York City, she completed the Susan G. Komen/University of Michigan Multidisciplinary Breast Fellowship in Ann Arbor.  She is board-certified in General Surgery and joined the Moffitt Cancer Center’s Comprehensive Breast Program as an Assistant Professor in 2008.  She was promoted to Associate Professor in 2014.  She is a Fellow of the American College of Surgeons and the Society of University Surgeons.  In addition to her clinical interests in young breast cancer patients, she is active in clinical research, clinical trials, and translational breast cancer research.  She is actively involved with her colleagues in investigating and improving fertility preservation education and collaborating with the faculty in Molecular and Functional Imaging in the development of novel agents for intraoperative identification of breast cancer.  She is the recipient of NIH/NCI and private research funding.  She has numerous publications in peer-reviewed medical journals and has presented her work regionally and nationally.

Education & Training

Board Certification:

  • Surgery

Fellowship:

  • University of Michigan Cancer Center - Surgical Breast Oncology

Residency:

  • Lenox Hill Hospital - General Surgery
  • Lenox Hill Hospital - General Surgery

Medical School:

  • Northeastern Ohio Universities College of Medicine - MD
Participating Trials

CLINICAL TRIAL 15769
Prospective Nipple-Areola Skin-Sparing Mastectomy
Condition: Breast
Intervention: Not Applicable
Open

CLINICAL TRIAL 18356
A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients who have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy
Condition: Breast
Intervention:
Open

CLINICAL TRIAL 18386
A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy
Condition: Breast
Intervention: Not Applicable
Open

CLINICAL TRIAL 18899
Alternative Dosing of Exemestane in Postmenopausal Women with Stage 0-II ER-Positive Breast Cancer: a Randomized Presurgical Trial
Condition: Breast
Intervention: Aromasin (Exemestane); Exemestane
Open

CLINICAL TRIAL 17268
I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2)
Condition: Breast
Intervention: AMG 386; Adriamycin (doxorubicin); BMN-673 (Talazoparib); CPT-11 (irinotecan); Camptosar (irinotecan); Ganetespib (STA-9090); Ganitumab; Herceptin (Trastuzumab); MK-2206; Not Applicable; PLX3397; Patritumab; Pembrolizumab (Keytruda); Pertuzumab; T-DM1; Talazoparib; Taxol (paclitaxel); Trastuzumab; U3-1287 (Patritumab); cyclophosphamide; cytoxan (cyclophosphamide); doxorubicin; irinotecan; paclitaxel; rhuMAb HER2 (Trastuzumab)
Open

CLINICAL TRIAL 18596
A Phase II Study of Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer: Introduction of a Novel Form of Accelerated Partial Breast Radiotherapy
Condition: Breast
Intervention: Not Applicable
Open

CLINICAL TRIAL 18621
A Phase 1/2 Study of Talimogene laherparepvec in Combination with Neoadjuvant Chemotherapy in Triple Negative Breast Cancer
Condition: Breast
Intervention: Adriamycin (doxorubicin); Talimogene laherparepvec 10^6 PFU (Talimogene Laherparepvec); Talimogene laherparepvec 10^8 PFU (Talimogene Laherparepvec); Taxol (paclitaxel); cyclophosphamide; cytoxan (cyclophosphamide); doxorubicin; paclitaxel
Open

If you believe you are eligible for one of these trials or studies, please call
1-888-MOFFITT (1-888-663-3488).

Publications

  • Dossett LA, Hudson JN, Morris AM, Lee MC, Roetzheim RG, Fetters MD, Quinn GP. The primary care provider (PCP)-cancer specialist relationship: A systematic review and mixed-methods meta-synthesis. CA-Cancer J Clin. 2017 Mar;67(2):156-169. Pubmedid: 27727446. Pmcid: PMC5342924.
  • Mattingly AE, Mooney B, Lin HY, Kiluk JV, Khakpour N, Hoover SJ, Laronga C, Lee MC. Magnetic Resonance Imaging for Axillary Breast Cancer Metastasis in the Neoadjuvant Setting: A Prospective Study. Clin Breast Cancer. 2017 Jun;17(3):180-187. Pubmedid: 27956116.
  • Dossett LA, Kauffmann RM, Lee JS, Singh H, Lee MC, Morris AM, Jagsi R, Quinn GP, Dimick JB. Specialist Physicians' Attitudes and Practice Patterns Regarding Disclosure of Pre-Referral Medical Errors. Ann Surg. 2017 Jul. Pubmedid: 28742712.
  • Collins M, O'Donoghue C, Sun W, Zhou JM, Ma Z, Laronga C, Lee MC. Use of axillary lymph node dissection (ALND) in patients with micrometastatic breast cancer. J Surg Res. 2017 Jul;215:55-59. Pubmedid: 28688661 .
  • Nocera NF, Lee MC, Czerniecki BJ. Boosting anti-HER2 CD4 T-helper responses in HER2 expressing ductal carcinoma in situ. Future Oncol. 2017 Jul;13(17):1459-1462. Pubmedid: 28766964.
  • Mellon EA, Orman A, Joya LE, Montejo ME, Laronga C, Hoover SJ, Lee MC, Khakpour N, Kubal PF, Diaz R. Frequency of whole breast radiation therapy after intraoperative radiation therapy due to criteria identified by lumpectomy. Brachytherapy. 2017 Jul;16(1):174-180. Pubmedid: 27816540.
  • Collins M, O'Donoghue C, Sun W, Zhou JM, Ma Z, Laronga C, Lee MC. Use of axillary lymph node dissection (ALND) in patients with micrometastatic breast cancer. J Surg Res. 2017 Jul;215:55-59. Pubmedid: 28688661.
  • González SJ, Mooney B, Lin HY, Zhao X, Kiluk JV, Khakpour N, Laronga C, Lee MC. 2-D and 3-D Ultrasound for Tumor Volume Analysis: A Prospective Study. Ultrasound Med Biol. 2017 Apr;43(4):775-781. Pubmedid: 28187928.
  • Mattingly AE, Kiluk JV, Lee MC. Clinical Considerations of Risk, Incidence, and Outcomes of Breast Cancer in Sexual Minorities. Cancer Control. 2016 Oct;23(4):373-382. Pubmedid: 27842326.
  • Dossett LA, Lowe J, Sun W, Lee MC, Smith PD, Jacobsen PB, Laronga C. Prospective evaluation of skin and nipple-areola sensation and patient satisfaction after nipple-sparing mastectomy. J Surg Oncol. 2016 Jul;114(1):11-16. Pubmedid: 27087574.
  • Nocera NF, Lee MC, De La Cruz LM, Rosemblit C, Czerniecki BJ. Restoring Lost Anti-HER-2 Th1 Immunity in Breast Cancer: A Crucial Role for Th1 Cytokines in Therapy and Prevention. Front Pharmacol. 2016;7:356. Pubmedid: 27766079. Pmcid: PMC5052279.
  • Lee MC, Gonzalez SJ, Lin H, Zhao X, Kiluk JV, Laronga C, Mooney B. Prospective trial of breast MRI versus 2D and 3D ultrasound for evaluation of response to neoadjuvant chemotherapy. Ann Surg Oncol. 2015 Sep;22(9):2888-2894. Pubmedid: 25589151.
  • Snow R, Reyna C, Johns C, Lee MC, Sun W, Fulp WJ, Kiluk JV, Laronga C. Outcomes with and without axillary node dissection for node-positive lumpectomy and mastectomy patients. Am J Surg. 2015 Oct;210(4):685-693. Pubmedid: 26210706.
  • Jacobsen PB, Lee M. Integrating Psychosocial Care Into Routine Cancer Care. Cancer Control. 2015 Oct;22(4):442-449. Pubmedid: 26678971.
  • Quinn GP, Block RG, Clayman ML, Kelvin J, Arvey SR, Lee JH, Reinecke J, Sehovic I, Jacobsen PB, Reed D, Gonzalez L, Vadaparampil ST, Laronga C, Lee MC, Pow-Sang J, Eggly S, Franklin A, Shah B, Fulp WJ, Hayes-Lattin B. If you did not document it, it did not happen: rates of documentation of discussion of infertility risk in adolescent and young adult oncology patients' medical records. J Oncol Pract. 2015 Mar;11(2):137-144. Pubmedid: 25549654. Pmcid: PMC4799849.
  • Acs G, Khakpour N, Kiluk J, Lee MC, Laronga C. The presence of extensive retraction clefts in invasive breast carcinomas correlates with lymphatic invasion and nodal metastasis and predicts poor outcome: a prospective validation study of 2742 consecutive cases. Am J Surg Pathol. 2015 Mar;39(3):325-337. Pubmedid: 25353283.
  • Roetzheim RG, Lee JH, Fulp W, Matos Gomez E, Clayton E, Tollin S, Khakpour N, Laronga C, Lee MC, Kiluk JV. Acceptance and adherence to chemoprevention among women at increased risk of breast cancer. Breast. 2015 Feb;24(1):51-56. Pubmedid: 25491191. Pmcid: PMC4503358.
  • Agostinho JL, Zhao X, Sun W, Laronga C, Kiluk JV, Chen DT, Lee MC. Prediction of positive margins following breast conserving surgery. Breast. 2015 Feb;24(1):46-50. Pubmedid: 25466503.
  • Patel BK, Jafarian N, Abbott AM, Khazai L, Lee MC. Imaging Findings and Management of Primary Breast Cancer in Accessory Axillary Breast Tissue. Clin Breast Cancer. 2015 Aug;15(4):e223-e229. Pubmedid: 25986957.
  • Goble RN, Drukteinis JS, Lee MC, Khakpour N, Kiluk JV, Laronga C. Early experience with ultrasound features after intrabeam intraoperative radiation for early stage breast cancer. J Surg Oncol. 2014 Jun;109(8):751-755. Pubmedid: 24862923.
  • Kiluk JV, Prowler V, Lee MC, Khakpour N, Laronga C, Cox CE. Contralateral axillary nodal involvement from invasive breast cancer. Breast. 2014 Jun;23(3):291-294. Pubmedid: 24709584.
  • Lee MC, Laronga C. The pregnant breast cancer patient: are we failing our most vulnerable population?. Ann Surg Oncol. 2014 Aug;21(8):2474-2475. Pubmedid: 24743913.
  • Prowler VL, Joh JE, Acs G, Kiluk JV, Laronga C, Khakpour N, Lee MC. Surgical excision of pure flat epithelial atypia identified on core needle breast biopsy. Breast. 2014 Aug;23(4):352-356. Pubmedid: 24518220.
  • Williams M, Eatrides J, Kim J, Talwar H, Esposito N, Szabunio M, Ismail-Khan R, Kiluk J, Lee M, Laronga C, Khakpour N. Comparison of breast magnetic resonance imaging clinical tumor size with pathologic tumor size in patients status post-neoadjuvant chemotherapy. Am J Surg. 2013 Oct;206(4):567-573. Pubmedid: 23809673.
  • Lee MC, Bhati RS, von Rottenthaler EE, Reagan AM, Karver SB, Reich RR, Quinn GP. Therapy choices and quality of life in young breast cancer survivors: a short-term follow-up. Am J Surg. 2013 Nov;206(5):625-631. Pubmedid: 24016705. Pmcid: PMC4503361.
  • Doren EL, Parikh RP, Laronga C, Hiro ME, Sun W, Lee MC, Smith PD, Fulp WJ. Sequelae of fat grafting postmastectomy: an algorithm for management of fat necrosis. Eplasty. 2013 Jan;12:e53. Pubmedid: 23308300. Pmcid: PMC3516285.
  • Walsh N, Greene J, Catherine Lee M. Tuberculous adenopathy masquerading as locally advanced breast cancer. Breast J. 2013 Jan;19(1):106-107. Pubmedid: 23279334.
  • Walsh N, Kiluk JV, Sun W, Khakpour N, Laronga C, Lee MC. Ipsilateral nodal recurrence after axillary dissection for breast cancer. J Surg Res. 2012 Sep;177(1):81-86. Pubmedid: 22498028.
  • Lee MC, Joh JE, Chau A. Axillary staging prior to neoadjuvant chemotherapy: the roles of sentinel lymph node biopsy and axillary ultrasonography. Cancer Control. 2012 Oct;19(4):277-285. Pubmedid: 23037495.
  • Joh JE, Esposito NN, Kiluk JV, Laronga C, Khakpour N, Soliman H, Catherine Lee M. Pathologic Tumor Response of Invasive Lobular Carcinoma to Neo-adjuvant Chemotherapy. Breast J. 2012 Nov;18(6):569-574. Pubmedid: 23034096.
  • Joh JE, Esposito NN, Kiluk JV, Laronga C, Lee MC, Loftus L, Soliman H, Boughey JC, Reynolds C, Lawton TJ, Acs PI, Gordan L, Acs G. The effect of Oncotype DX recurrence score on treatment recommendations for patients with estrogen receptor-positive early stage breast cancer and correlation with estimation of recurrence risk by breast cancer specialists. Oncologist. 2012 Jun;16(11):1520-1526. Pubmedid: 22016474. Pmcid: PMC3233285.
  • Lee MC, Plews R, Rawal B, Kiluk JV, Loftus L, Laronga C. Factors affecting lymph node yield in patients undergoing axillary node dissection for primary breast cancer: a single-institution review. Ann Surg Oncol. 2012 Jun;19(6):1818-1824. Pubmedid: 22203185.
  • Turaga KK, Chau A, Eatrides JM, Kiluk JV, Khakpour N, Laronga C, Lee MC. Selective application of routine preoperative axillary ultrasonography reduces costs for invasive breast cancers. Oncologist. 2012 Jan;16(7):942-948. Pubmedid: 21572122. Pmcid: PMC3228129.
  • Joh JE, Han G, Kiluk JV, Laronga C, Khakpour N, Lee MC. Indications for axillary ultrasound use in breast cancer patients. Clin Breast Cancer. 2012 Dec;12(6):433-437. Pubmedid: 23062709.
  • Kiluk JV, Lee MC, Park CK, Meade T, Minton S, Harris E, Kim J, Laronga C. Male Breast Cancer: Management and Follow-up Recommendations. Breast J. 2011 Sep;17(5):503-509. Pubmedid: 21883641.
  • Pimiento JM, Lee MC, Esposito NN, Kiluk JV, Khakpour N, Carter WB, Han G, Laronga C. Role of axillary staging in women diagnosed with ductal carcinoma in situ with microinvasion. J Oncol Pract. 2011 Sep;7(5):309-313. Pubmedid: 22211128. Pmcid: PMC3170064.
  • Pimiento JM, Gadgil PV, Santillan AA, Lee MC, Esposito NN, Kiluk JV, Khakpour N, Hartley TL, Yeh IT, Laronga C. Phyllodes tumors: race-related differences. J Am Coll Surg. 2011 Oct;213(4):537-542. Pubmedid: 21856184.
  • Lee MC, Eatrides J, Chau A, Han G, Kiluk JV, Khakpour N, Cox CE, Carter WB, Laronga C. Consequences of axillary ultrasound in patients with T2 or greater invasive breast cancers. Ann Surg Oncol. 2011 Jan;18(1):72-77. Pubmedid: 20585876.
  • Kiluk JV, Khakpour N, Lee MC, Lowe J, Harris E, Szabunio M, Laronga C. Management of abnormal Rotter's lymph nodes identified on preoperative breast magnetic resonance imaging. Am Surg. 2011 Jan;77(1):E10-E12. Pubmedid: 21396292.
  • Lee MC, Gray J, Han HS, Plosker S. Fertility and reproductive considerations in premenopausal patients with breast cancer. Cancer Control. 2010 Jul;17(3):162-172. Pubmedid: 20664513.
  • Lee M, Rogers K, Griffith K, Diehl K, Breslin T, Cimmino V, Chang A, Newman L, Sabel M. Determinants of breast conservation rates: reasons for mastectomy at a comprehensive cancer center. Breast J. 2009 Jan;15(1):34-40. Pubmedid: 19141132.
  • Laronga C, Lee MC, McGuire KP, Meade T, Carter WB, Hoover S, Cox CE. Indications for sentinel lymph node biopsy in the setting of prophylactic mastectomy. J Am Coll Surg. 2009 Dec;209(6):746-752. Pubmedid: 19959044.
  • Lee MC, Kilbride KE. Timing of Axillary Staging. Ann Surg Oncol. 2009 Apr;16(4):1065-1065. Pubmedid: 19198950.
  • Lee M, Newman L. Management of patients with locally advanced breast cancer. Surg Clin North Am. 2007 Apr;87(2):379-398. Pubmedid: 17498533.
  • Lee M, Jagsi R. Postmastectomy radiation therapy: indications and controversies. Surg Clin North Am. 2007 Apr;87(2):511-526. Pubmedid: 17498541.
  • Chorost M, Lee M, Yeoh C, Molina M, Ghosh B. Unknown primary. J Surg Oncol. 2004 Sep;87(4):191-203. Pubmedid: 15334635.
  • Lee M, Lehman JA J, Tantri M, Parker M, Wagner D. Bilateral reduction mammoplasty in an adolescent population: adolescent bilateral reduction mammoplasty. J Craniofac Surg. 2003 Sep;14(5):691-695. Pubmedid: 14501330.