New Chemoprevention Study Aims to Prevent Lung Cancer

By Kim Polacek, APR, CPRC - November 29, 2020

It’s a term that is often misunderstood in cancer — chemoprevention. Cancer chemoprevention is the use of substances to prevent or stop the growth of cancer. These substances can be natural or made in a laboratory and are often used in those who are at high risk of developing cancer or to prevent recurrence in patients who have battled the disease.

Dr. Nagi Kumar
Dr. Nagi Kumar, Director, Cancer Chemoprevention Research Interest Group

Led by Dr. Nagi Kumar, the Cancer Chemoprevention Research Interest Group at Moffitt Cancer Center is working to develop new cancer chemoprevention regimens for different types of cancers, including brain, bladder and prostate.

Kumar’s latest study focuses on the prevention of lung cancer. She is seeking former smokers who are at high risk for lung cancer and who have been screened and diagnosed with a lung nodule. A lung nodule is an abnormal mass found in the lung. A nodule does not necessarily mean cancer is present. However, when found in current or former smokers, doctors may evaluate these nodules carefully, testing the nodule for cancerous cells and/or monitoring it over time.

“Our study utilizes two compounds in hopes of shrinking or stopping lung nodules in former smokers from potentially growing to become cancer,” said Kumar.

Study Eligibility

Qualified participants are:
• 55 years or older
• Former smokers
• Diagnosed with a lung nodule using CT scan

The two compounds that will be used as chemoprevention agents include curcumin, a substance found in the turmeric root, and Lovaza, an omega-3 fatty acid formulation that is found in fish such as salmon and red snapper.  Both curcumin and omega-3 fatty acids have anti-inflammatory properties. Additionally, omega-3 has been shown to resolve the damage that has been caused to lung tissue from prolonged smoking.

Study participants will be required to have a low-dose CT scan as part of the screening for lung nodules and bloodwork done at their first visit. They will then come back for additional screenings at three and six months.

For more information, please call 813-745-3081.

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Kim Polacek, APR, CPRC Senior PR Account Coordinator More Articles

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