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CLINICAL TRIAL 18858

A Phase 1/2a Open-Label Study to Determine the Safety and Tolerability of ALRN-6924 in Patients with Advanced Solid Tumors or Lymphomas Expressing Wild-Type p53 Protein

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18964

Randomized Double-Blind Phase III Study of Ibrutinib During and Following Autologous Stem Cell Transplantation Versus Placebo in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma of the Activated B-cell Subtype

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CLINICAL TRIAL 19511

Immune Mechanisms of Resistance to CD19 CAR T cells in Lymphoma

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CLINICAL TRIAL 19642

A Phase 1B Study of AZD9291 in Combination with Navitoclax in EGFR-mutant Non-Small Cell Lung Cancer Following Resistance to Initial EGFR Kinase Inhibitor

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CLINICAL TRIAL 19105

A Phase 1b Study of Safety and Immune Response to PVX-410 Vaccine Alone and in Combination with an Antibody Targeting the PD-1/PD-L1 Pathway in HLA-A2+ Subjects Who Have Completed Initial Standard Treatment of Stage II or III Triple Negative Breast Cancer (TNBC)

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CLINICAL TRIAL 19442

Adaptive Tyrosine Kinase Inhibitor Therapy In Patients With Advanced Progressive Thyroid Cancer

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CLINICAL TRIAL 18844

A Phase 2 Study of Cediranib in Combination with Olaparib in Advanced Solid Tumors

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CLINICAL TRIAL 19636

Assessing the Impacts of Sensorimotor Stimuli and Nicotine Content on Cravings and Other Outcomes of E-Cigarette Use

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CLINICAL TRIAL 19601

A Randomized, Double-Blind Phase 2/3 Study of Relatlimab Combined with Nivolumab versus Nivolumab in Participants with Previously Untreated Metastatic or Unresectable Melanoma

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CLINICAL TRIAL 19625

A Phase 1b Dose-Escalation Study Of TRC105 In Combination With Nivolumab In Patients With Metastatic Non-Small Cell Lung Cancer

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CLINICAL TRIAL 19478

Minimally Invasive Bronchoscopic Biorepository for Lung Cancer Evaluation

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CLINICAL TRIAL 19634

Study of Resistance Mechanisms to Checkpoint Blockade

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CLINICAL TRIAL 18959

A Phase 2 Study to Evaluate the Safety, Tolerability and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-145) followed by IL-2 in Patients with Recurrent and/or Metastatic Cervical Carcinoma

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CLINICAL TRIAL 19163

Combination Immunotherapy with Ipilimumab and Nivolumab plus a Dendritic Cell based p53 Vaccine (Ad.p53-DC) in patients with relapsed Small Cell Lung Cancer (SCLC)

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CLINICAL TRIAL 19327

A Phase 2 Trial of Pembrolizumab Plus Bevacizumab in Patients with Metastatic Melanoma or Non-small Cell Lung Cancer with Untreated Brain Metastases

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CLINICAL TRIAL 19577

A Phase 1 Multiple Dose Study to Evaluate the Safety and Tolerability of XmAb®18087 in Subjects with Advanced Neuroendocrine and Gastrointestinal Stromal Tumors

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CLINICAL TRIAL 19641

A Randomized Phase 2 Study of Cabozantinib in Combination with Nivolumab in Advanced, Recurrent Metastatic Endometrial Cancer.

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CLINICAL TRIAL 19568

A Randomized Phase 2 Study of Cediranib in Combination with Olaparib versus Olaparib Alone in Men with Metastatic Castration Resistant Prostate Cancer.

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CLINICAL TRIAL 19580

A Phase 1/2 Dose Escalation and Dose Expansion Study of BA3011 in Patients with Advanced Solid Tumors

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CLINICAL TRIAL 19472

OsteoCool Tumor Ablation Post-Market Study (OPuS One)

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CLINICAL TRIAL 18612

A Randomized Phase II/III Study of Adjuvant Concurrent Radiation and Chemotherapy versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors

Cancer Type: Head & Neck

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CLINICAL TRIAL 19695

S1602: A Phase III Randomized Trial to Evaluate the Influence of BCG Strain Differences and T Cell Priming with Intradermal BCG Before Intravesical Therapy for BCG‐Naïve High‐Grade Non‐Muscle Invasive Bladder Cancer.

Cancer Type: Genitourinary

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CLINICAL TRIAL 18329

A Phase 1/2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Subjects with Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r ALL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19737

S1712, " A Randomized Phase II Study of Ruxolitinib in Combination with BCR-ABL Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Patients with Evidence of Molecular Disease.- Study Chairs: Kendra Sweet, M.D., Jerald P. Radich, M.D.

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19724

Managed Access Program (MAP) To Provide Access To CTL019, For Acute Lymphoblastic Leukemia (ALL) Or Diffuse Large B-Cell Lymphoma (DLBCL) Patients With Out Of Specification Leukapheresis Product And/Or Manufactured Tisagenlecleucel Out Of Specification For Commercial Release

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19683

A Phase 1, Open-Label, Multicenter, Dose-Escalation Study of RMC-4630 Monotherapy in Adult Participants with Relapsed/Refractory Solid Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 19466

Exploring Adherence to CDK4/6 Inhibitors among Metastatic Breast Cancer Patients

Cancer Type: Breast

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CLINICAL TRIAL 19582

An Open-Label, Multi-Center Trial of INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination with REGN2810 in Subjects with Newly-Diagnosed Glioblastoma (GBM)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 50293

Analysis of Immune Infiltrates of Melanoma Tissue

Cancer Type: Cutaneous

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CLINICAL TRIAL 18331

Selection of Allogeneic Hematopoietic Cell Donors Based on KIR and HLA Genotypes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 17799

A Phase I Dose Escalation Trial of Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of the Head and Neck

Cancer Type: Head & Neck

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CLINICAL TRIAL 17929

A Phase I/II, Multicenter, Open-label, Dose Escalation and Randomized Trial of BI 836858 in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 16962

A Phase I Trial of Dose Escalation of Metformin in Combination with Vincristine, Irinotecan, and Temozolomide in Children with Relapsed or Refractory Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 17263

Phase I Trial of ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 17716

A Biomarker-related Approach to Screening for HPV-related Oropharyngeal Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 18435

Phase II study of Copanlisib (BAY 80-6946) in Combination with Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 18232

Addressing Tobacco Health Disparities via Group Intervention

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 17723

Expansion of Enduring Infrastructure to Support Lung Cancer Screening Research

Cancer Type: Thoracic

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CLINICAL TRIAL 18225

Efficacy of MBSR Treatment on Cognitive Impairment among Breast Cancer Survivors

Cancer Type: Breast

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CLINICAL TRIAL 17970

A Randomized Phase III Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Observation for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

Cancer Type: Thoracic

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CLINICAL TRIAL 18862

A Phase 1, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of SGN-LIV1A in Patients with LIV-1-Positive Metastatic Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 18837

An Open-Label Study of Rovalpituzumab Tesirine in Subjects with Delta-Like Protein 3-Expressing Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 18643

Biobank for African American Prostate Cancer Research in Florida

Cancer Type: Genitourinary

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CLINICAL TRIAL 18664

A Phase 2, Multi-Center Study of High Dose Chemotherapy with Autologous Stem Cell Transplant Followed by Maintenance Therapy with Romidepsin for the Treatment of T cell Non-Hodgkin's Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18646

Phase I Study of Pre-operative Capecitabine and Lenvatinib with External Radiation Therapy in Locally Advanced Rectal Adenocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 18828

Smartphone-Based Assessment of Patient-Reported Outcomes Related to Receipt of Immunotherapy

Cancer Type: Head & Neck

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CLINICAL TRIAL 18304

A Phase II Trial of AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 18871

A Phase Ii, Open-Label, Multicenter, Single-Arm Study To Investigate TheEfficacy And Safety Of Atezolizumab As Neoadjuvant And Adjuvant Therapy In Patients With Stage Ib, Ii, Iiia Or Selected Iiib Resectable And Untreated Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 18899

Alternative Dosing of Exemestane in Postmenopausal Women with Stage 0-II ER-Positive Breast Cancer: a Randomized Presurgical Trial

Cancer Type: Breast

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CLINICAL TRIAL 18939

An Open-label, Multicenter Phase 1 Trial to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Splicing Modulator H3B-8800 for Subjects With Myelodysplastic Syndromes, Acute Myeloid Leukemia, and Chronic Myelomonocytic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18596

A Phase II Study of Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer: Introduction of a Novel Form of Accelerated Partial Breast Radiotherapy

Cancer Type: Breast

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CLINICAL TRIAL 18783

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18494

A Phase I/II Study of Pembrolizumab and Vorinostat in Patients with Immune Therapy Naïve and Immune Therapy Pretreated Stage IV NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 18788

A Phase 2 Study of Check Point Inhibitor, Durvalumab (MEDI4736) for Bacillus Calmette-Guérin (BCG) Refractory Urothelial Carcinoma in Situ (CIS) of the Bladder

Cancer Type: Genitourinary

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CLINICAL TRIAL 17268

I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2)

Cancer Type: Breast

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CLINICAL TRIAL 18999

Early Detection of Cancer Progression: Leveraging Team Science

Cancer Type: Thoracic

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CLINICAL TRIAL 19136

Randomized Phase II Study To Assess The Role Of Nivolumab As Single Agent To Eliminate Minimal Residual Disease And Maintain Remission In Acute Myelogenous Leukemia (AML) Patients After Chemotherapy (REMAIN TRIAL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18811

Randomized, Double-Blind, Phase 2/3 Study in Subjects with Malignant Pleural Mesothelioma with Low Argininosuccinate Synthetase 1 Expression to Assess ADI-PEG 20 with Pemetrexed and Cisplatin (ATOMIC-Meso Phase 2/3 Study)

Cancer Type: Thoracic

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CLINICAL TRIAL 18975

A Phase 2 Study of REGN2810, a Fully Human Monoclonal Antibody to Programmed Death-1, in Patients with Advanced Basal Cell Carcinoma who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy

Cancer Type: Cutaneous

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CLINICAL TRIAL 19112

DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 18980

A Phase III, Multicenter, Randomized,Placebo-Controlled, Double-Blind Study of Atezolizumab (AntiPd-L1 Antibody) as Adjuvant Therapy in Patients with Renal Cell Carcinoma at High Risk of Developing Metastasis Following Nephrectomy

Cancer Type: Genitourinary

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CLINICAL TRIAL 19101

A Phase 1/2a Study of BMS-986205 Administered in Combination with Nivolumab anti-PD-1 Monoclonal Antibody) and in Combination with Both Nivolumab and Ipilimumab (anti-CTLA-4 Monoclonal Antibody) in Advanced Malignant Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 18926

The National Myelodysplastic Syndromes (MDS) Study

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18630

Phase 1/2 Investigator Sponsored Study of Selinexor in Combination with High-Dose Melphalan Before Autologous Hematopoietic Cell Transplantation for Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18986

TRITON2: A Multicenter, Open-label Phase 2 Study of Rucaparib in Patients with Metastatic Castration-resistant Prostate Cancer Associated with Homologous Recombination Deficiency.

Cancer Type: Genitourinary

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CLINICAL TRIAL 18810

Phase 1b Study To Assess The Safety, Tolerability, and Clinical Activity of Gedatolisib in Combination with Palbociclib and Either Letrozole Or Fulvestrant in Women with Metastatic or Locally Advanced/Recurrent Breast Cancer (Mbc)

Cancer Type: Breast

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CLINICAL TRIAL 18936

A Phase I-II Study of Interferon-gamma Plus Weekly Paclitaxel, Trastuzumab and Pertuzumab in Patients with HER-2 Positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19203

Reduced Intensity Conditioning for Haploidentical Bone Marrow Transplantation in Patients with Symptomatic Sickle Cell Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18994

Phase II Randomized Trial of Radiotherapy with or without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) with TP53 Sequencing

Cancer Type: Head & Neck

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CLINICAL TRIAL 19230

Phase 2, Randomized, Open-Label Study Comparing Daratumumab, Lenalidomide, Bortezomib,and Dexamethasone (D-RVd) Versus Lenalidomide, Bortezomib, and Dexamethasone (RVd) in Subjects With Newly Diagnosed Multiple Myeloma Eligible for High-Dose Chemotherapy and Autologous Stem Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19150

A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 and TGR-1202 alone in Patients A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 With or Without Bendamustine and TGR-1202 Alone in Patients With Previously Treated Non-Hodgkin's Lymphoma with Previously Treated Diffuse Large B-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19122

A Phase I Clinical Trial Combining Nivolumab and Tumor Infiltrating Lymphocytes (TIL) for Patients with Advanced Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19194

A Phase 1 Study of bb21217, an anti-BCMA CAR T Cell Drug Product, in Relapsed and/or Refractory Multiple Myeloma

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL 19181

Patient-Reported Outcomes in Immunotherapy for Head and Neck Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 18610

A Phase I-II Study of Triciribine Phosphate Monohydrate (PTX-200) Plus Cytarabine in Refractory or Relapsed Acute Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18855

Multicenter, Open-label, Phase 1, Dose-escalation,Cohort-expansion, First-in-Human Study of KHK2455 Administered as Monotherapy and in Combination with Mogamulizumab (KW-0761) in Adult Subjects with Locally Advanced or Metastatic Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 19302

A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-033, an anti-LAG-3 Monoclonal Antibody, alone and in combination with an anti-PD-1 in Patients with Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 19396

A Phase 1/2 Study to Assess the Safety and Efficacy of Intratumoral IMO-2125 in Combination with Ipilimumab or Pembrolizumab in Patients with Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19421

A Phase 3, Randomized, Single Dose, Open-Label Study to Investigate the Safety and Efficacy of OTL38 Injection (OTL38) for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 17969

Randomized Study of Erlotinib vs. Observation in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 17690

A Phase I Trial of Single Agent Trametinib (GSK1120212) in Advanced Cancer Patients with Hepatic Dysfunction

Cancer Type: Multiple

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CLINICAL TRIAL 19296

A Randomized, Double-blind, Placebo-controlled Study of 4-hydroxytamoxifen Topical Gel in Women with Mammographically Dense Breast

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 18496

An Open Label Phase II Study of Tipifarnib in Subjects with Relapsed or Refractory Peripheral T-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19322

A Phase 1b Trial of Hu5F9-G4 Monotherapy or Hu5F9-G4 in Combination with Azacitidine in Patients with Hematological Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19404

A Phase 1/2 Open-Label Multicenter Study of CC-122 in Combination with R-CHOP-21 for Previously Untreated Poor-Risk (IPI>/= 3) Diffuse Large B-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19430

Phase 1/2 Study of TEW-7197 Monotherapy in Patients with Low or Intermediate Myelodysplastic Syndromes (MDS)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19379

A Phase 2, Multicenter, Open-Label Study To Evaluate The Efficacy And Safety Of Luspatercept (Ace-536) In Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis And Anemia With And Without Red Blood Cell-Transfusion Dependence

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19319

InPACT- International Penile Advanced Cancer Trial (International Rare Cancers Initiative study)

Cancer Type: Genitourinary

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CLINICAL TRIAL 19339

A Phase II Trial of AZD9291 (Osimertinib) with or without Bevacizumab in Patients with EGFR Mutation Positive NSCLC and Brain Metastases

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19394

An Open-Label, Single-Arm Pilot Study Evaluating The Antitumor Activity And Safety Of Niraparib As Neoadjuvant Treatment In Localized, Her2-Negative, Brca-Mutant Breast Cancer Patients

Cancer Type: Breast

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CLINICAL TRIAL 19587

Neurofibroma and MPNST Tumor Progression in Neurofibromatosis Type 1 (NF1) -- Genomic, Histological and Clinical Analysis, an NF Research MPNST Genomic Consortium (GeM) Project: Part 2 -- Prospective Recruitment, Tissue Collection, and Analysis

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19484

Collection of Blood Mononuclear Cells by Apheresis from Compensated Volunteer Healthy Donors

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19480

The Reveal Study: A Phase 1/2, Open-Label, Multicenter, Dose Escalation And Dose Expansion Study Of Nktr-262 In Combination With Nktr-214 And In combination With Nktr-214 Plus Nivolumab In Patients With Locally Advanced Or Metastatic Solid Tumor Malignancies

Cancer Type: Multiple

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CLINICAL TRIAL 19485

A Phase I/II, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 using the Intra-patient Escalation Dosing Regimen in Patients with Advanced Uveal Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19603

Single Arm, Open Label Phase 1b/2 Study of SGN-LIV1A in Combination with Pembrolizumab for First-Line Treatment of Patients with Unresectable Locally-Advanced or Metastatic Triple-Negative Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19428

A Phase 1/2, Multicenter, Dose-Escalation and Expansion Study of Combination Therapy with Venetoclax, Daratumumab and Dexamethasone (With and Without Bortezomib) in Subjects with Relapsed or Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19077

Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer also Receiving Cisplatin or Carboplatin and Etoposide

Cancer Type: Thoracic

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CLINICAL TRIAL 19429

A Phase 2 Single-Arm, Open-Label Study Evaluating Tolerability and Efficacy of Navitoclax in Combination with Ruxolitinib in Subjects with Myelofibrosis

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19501

Project ACTS (Adherence to CT Screening): Development and Usability of Patient Engagement Tools to Support Lung Cancer Screening Adherence

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19475

Phase 2 Study of Ceritinib in Patients with Unresectable Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 50259

Understanding the Dynamic Composition of Immune Subpopulations in the Course of Multiple Myeloma Disease Progression and Emergence of Drug Resistance

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL 19642

A Phase 1B Study of AZD9291 in Combination with Navitoclax in EGFR-mutant Non-Small Cell Lung Cancer Following Resistance to Initial EGFR Kinase Inhibitor

Cancer Type: Thoracic

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CLINICAL TRIAL 19442

Adaptive Tyrosine Kinase Inhibitor Therapy In Patients With Advanced Progressive Thyroid Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 19327

A Phase 2 Trial of Pembrolizumab Plus Bevacizumab in Patients with Metastatic Melanoma or Non-small Cell Lung Cancer with Untreated Brain Metastases

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19163

Combination Immunotherapy with Ipilimumab and Nivolumab plus a Dendritic Cell based p53 Vaccine (Ad.p53-DC) in patients with relapsed Small Cell Lung Cancer (SCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 19636

Assessing the Impacts of Sensorimotor Stimuli and Nicotine Content on Cravings and Other Outcomes of E-Cigarette Use

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19601

A Randomized, Double-Blind Phase 2/3 Study of Relatlimab Combined with Nivolumab versus Nivolumab in Participants with Previously Untreated Metastatic or Unresectable Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19625

A Phase 1b Dose-Escalation Study Of TRC105 In Combination With Nivolumab In Patients With Metastatic Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19472

OsteoCool Tumor Ablation Post-Market Study (OPuS One)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19634

Study of Resistance Mechanisms to Checkpoint Blockade

Cancer Type: Cutaneous

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CLINICAL TRIAL 19732

Randomized, Double-Blinded Phase III Study of Cabozantinib Versus Placebo in Patients with Advanced Neuroendocrine Tumors after Progression on Everolimus (Cabinet)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 18786

A Phase 2, Randomized, Multi-institutional Study of Nivolumab and Ipilimumab versus Nivolumab, Ipilimumab and Stereotactic Body Radiation Therapy for Metastatic Merkel Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19579

Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy Fractionation for Patients with HPV+ Oropharyngeal Cancers.

Cancer Type: Head & Neck

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CLINICAL TRIAL 18844

A Phase 2 Study of Cediranib in Combination with Olaparib in Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 19504

An International, Multicenter, Open-label, Randomized, Phase 3 Study of BLU-285 vs Regorafenib in Patients with Locally Advanced Unresectable or Metastatic Gastrointestinal Stromal Tumor (GIST)

Cancer Type: Sarcoma

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CLINICAL TRIAL 19509

A Phase 1/2 Study Of Pegzilarginase (AEB1102, Co-Argi-PEG) In Combination With Pembrolizumab In The Treatment Of Patients With Extensive Disease (ED) Small Cell Lung Cancer (SCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 18430

Evaluation of Panobinostat (LBH589) as Maintenance Therapy in Multiple Myeloma Following Autologous Hematopoietic Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19360

Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant (ASCENT): A Phase 2 Trial of Induction, Consolidation and Maintenance in Subjects with High Risk Smoldering Multiple Myeloma (SMM)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19578

Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients

Cancer Type: Multiple

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CLINICAL TRIAL 18826

A Phase 1 Study of ALKS 4230 Administered Intravenously as Monotherapy and in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors

Cancer Type: Genitourinary

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CLINICAL TRIAL 19228

A Phase 2, Multi-Center, Open Label Study of NIR178 in Combination with PDR001 in Patients with Selected Advanced Solid Tumors and Non-Hodgkin lymphoma

Cancer Type: Thoracic

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CLINICAL TRIAL 18661

Phase I Trial of Hypofractionated Stereotactic Irradiation (HFSRT) Combined with Nivolumab, Ipilimumab and Bevacizumab in Patients with Recurrent High Grade Gliomas

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19609

A Phase 1, Multicenter, Open Label Study of AMV564, a Bispecific CD33/CD3 T-cell Engager, in Patients with Intermediate or High-Risk Myelodysplastic Syndromes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19482

A Single-Arm, Open-Label Phase 2 Pilot Study of Vyxeos (CPX-351) in Adults with Relapsed or Refractory Acute Lymphoblastic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19569

A Phase 1/2 Study of Combination Immunotherapy and mRNA Vaccine in Subjects with Non-small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 19581

Phase I study of Regorafenib and Nivolumab in Mismatch Repair (MMR) Proficient Advanced Refractory Colorectal Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19435

Combination of Nivolumab Immunotherapy with Radiation Therapy and Androgen Deprivation Therapy in the Management of Gleason Group 5 Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 19638

Effects of Acupressure on Chemotherapy-Induced Nausea and Vomiting

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19387

A Phase 2 Study of Poziotinib in Patients with Non-Small Cell Lung Cancer, (NSCLC), Locally Advanced or Metastatic, with EGFR or HER2 Exon 20 Insertion Mutation (ZENITH20)

Cancer Type: Thoracic

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CLINICAL TRIAL 18671

Facilitating Smoking Cessation with Reduced Nicotine Cigarettes

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19479

A Phase 1-2 Study of the Combination of Olaparib and Tremelimumab in BRCA1 and BRCA2 Mutation Carriers with Recurrent Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19632

A Phase Ib/II, Open-Label, Multicenter,Randomized Umbrella Study Evaluating The Efficacy And Safety Of Multiple Immunotherapy-Based Treatment Combinations In Patients With Metastatic Triple-Negative Breast Cancer (Morpheus-TNBC)

Cancer Type: Breast

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CLINICAL TRIAL 19584

A Phase 2, Open-Label, 2-Cohort, Multicenter Study of INCB050465, a PI3Kä Inhibitor, in Relapsed or Refractory Mantle Cell Lymphoma Previously Treated With or Without a BTK Inhibitor (CITADEL-205)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19647

A Randomized, Phase II Study of Ficlatuzumab with or without Cetuximab in Patients with Cetuximab-Resistant, Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Cancer Type: Head & Neck

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CLINICAL TRIAL 19604

A Phase II Multi-Center Study of SM-88 in Subjects with Pancreatic Cancer Whose Disease Has Progressed or Recurred after/on First Line Chemotherapy

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19656

Phase I Study of Ceritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 19630

Development of a Mindfulness-Based Treatment for the Reduction of Alcohol Use and Smoking Cessation

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19109

A Phase 1/2, Open-Label, Multicenter Study of the Combination of NKTR-214 and Nivolumab or the Combination of NKTR-214, Nivolumab and Other Anti-Cancer Therapies in Patients with Select Locally Advanced or Metastatic Solid Tumor Malignancies

Cancer Type: Genitourinary

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CLINICAL TRIAL 19389

A Phase 1, First-in-Human, Open-Label, Dose Escalation Study of JNJ-61186372, a Human Bispecific EGFR and cMet Antibody, in Subjects with Advanced Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19389

A Phase 1, First-in-Human, Open-Label, Dose Escalation Study of JNJ-61186372, a Human Bispecific EGFR and cMet Antibody, in Subjects with Advanced Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19575

Phase 3b Study for Management of Ocular Side Effects in Subjects with EGFR-Amplified Glioblastoma Receiving Depatuxizumab Mafodotin (ABT-414)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19495

A Multicenter, Randomized, Double Blinded, Placebo Controlled, Phase 3 trial of Adjuvant Avelumab (anti PDL1 antibody) in Merkel Cell Carcinoma Patients with Clinically Detected Lymph Node Metastases

Cancer Type: Cutaneous

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CLINICAL TRIAL 19697

An Open-Label, Multi-Center Trial of INO-5401 + INO-9012 in Combination with Atezolizumab in Subjects with Locally Advanced Unresectable or Metastatic/Recurrent Urothelial Carcinoma

Cancer Type: Genitourinary

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CLINICAL TRIAL 19704

Radiation and Chemotherapy with Ipilimumab followed by Nivolumab for Patients with Stage III Unresectable NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 19477

A Phase II study of TAS 102 in Combination with Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19611

The Effect of Acute Interpersonal Racial Discrimination on Smoking Motivation and Behavior among Black Smokers

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 14690

Total Cancer Care Protocol: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer

Cancer Type: Cancer Control

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CLINICAL TRIAL 16933

Older Breast Cancer Patients: Risk For Cognitive Decline

Cancer Type: Breast

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CLINICAL TRIAL 16028

Transdisciplinary Research in Colorectal Cancer: The ColoCare Study

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 16480

Radiomics: A Prospective Study of Outcome in Lung Cancer

Cancer Type: Multiple

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CLINICAL TRIAL 18523

A Validation Study on the Impact of Decipher® Testing on Treatment Recommendations in African-American and Non-African American Men with Prostate Cancer (VANDAAM Study)

Cancer Type: Genitourinary

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CLINICAL TRIAL 18744

A Phase I Trial of MEDI-570 in Patients with Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL) Follicular Variant and Angioimmunoblastic T-Cell Lymphoma (AITL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18682

Determinants of Age-Related Treatment Effectiveness in Ovarian Cancer: Prospective Study of Pharmacokinetics Patterns and Underlying Biology.

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 18431

A Screening Protocol to Determine Tumor Antigen Expression and HLA Sub-Type for Eligibility Determination for Clinical Trials Evaluating the Safety and Efficacy of Autologous T Cells Expressing Enhanced TCRs in Subjects with Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 18613

Phase II Study of nab-Paclitaxel in Combination with Gemcitabine for Treatment of Recurrent/Refractory Sarcoma in Teenagers and Young Adults

Cancer Type: Sarcoma

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CLINICAL TRIAL 18611

The Gut Microbiome and Immunotherapy in Non-small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 18356

A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients who have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL 17981

A Pilot Study of Adaptive Abiraterone Therapy for Metastatic Castration Resistant Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 18738

Developing a Patient- and Caregiver-Centered Psycho-Educational Tool to Support Recovery after Cystectomy

Cancer Type: Genitourinary

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CLINICAL TRIAL 18386

A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL 18847

Increasing HPV Vaccination Series Completion Rates among Adolescent Hispanics in Tampa and Ponce

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 18876

A Phase 1/1b Open-Label Study to Determine the Safety and Tolerability of ALRN-6924 alone and in Combination with Cytarabine (Ara-C) in Patients with Relapsed/Refractory Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome with Wild-Type TP53

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18814

A Multi-Center, Phase II Trial of HLA-Mismatched Unrelated Donor Bone Marrow Transplantation with Post-Transplantation Cyclophosphamide for Patients with Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18778

A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 18398

Novartis Pharmaceuticals trial entitled: A phase II, multicenter, study of oral cMET inhibitor INC280 in adult patients with EGFR wild-type (wt), advanced non-small cell lung cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 18503

STARTRK-2: An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients with Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements

Cancer Type: Thoracic

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CLINICAL TRIAL 18094

A Phase 2 Study of Transarterial Chemoperfusion Treatment with Cisplatin, Methotrexate and Gemcitabine in Patients with Unresectable Pleural Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL 18569

A Single-arm, Multi-Center, Open-Label Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Melphalan/HDS Treatment in Patients with Hepatic-Dominant Ocular Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 18959

A Phase 2 Study to Evaluate the Safety, Tolerability and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-145) followed by IL-2 in Patients with Recurrent and/or Metastatic Cervical Carcinoma

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 18891

A Multinational Open-Label, Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Administrations of NKR-2 in Patients with Different Metastatic Tumor Types

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19131

Contribution of Sleep Disruption and Physical Inactivity to Fatigue In Survivors of Allogeneic Hematopoietic Cell Transplant

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19003

A Randomized Phase 3 Trial of TRC105 and Pazopanib versus Pazopanib Alone In Patients with Advanced Angiosarcoma (TAPPAS)

Cancer Type: Sarcoma

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CLINICAL TRIAL 18944

A Phase 2 Study to Evaluate the Safety, Tolerability and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-145) followed by IL-2 in Patients with Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck

Cancer Type: Head & Neck

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CLINICAL TRIAL 18420

Patient Navigation in the Adolescent and Young Adult (AYA) Cancer Population

Cancer Type: Sarcoma

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CLINICAL TRIAL 19072

A Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma (iNHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18923

A Multi-Center Open-Label Phase 1/2 Study of BGB324 in Combination with Erlotinib in Patients with Stage IIIb or Stage IV Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 18933

Phase II Study of Pembrolizumab and Ipilimumab Following Initial Anti-PD1/L1 Antibody

Cancer Type: Cutaneous

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CLINICAL TRIAL 19068

Refinement of an Assessment Tool to Identify Cancer Survivorship Needs

Cancer Type: Multiple

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CLINICAL TRIAL 18083

Phase II Randomized Study of Lower Doses of Decitabine (DAC; 20 mg/m^2 IV daily for 3 days every month) versus Azacitidine (AZA; 75 mg/m^2 SC/IV daily for 3 days every month) versus Azcitidine (AZA; 75 mg/m^2 SC/IV daily for 5 days every month) in MDS Patients with Low and Intermediate-1 Risk Disease Transfusion-Dependent versus Best Supportive Care (BSC) in MDS Patients with Low and Intermediate-1 Risk Disease Transfusion-Independent

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19185

An Open Label, Single Arm Pilot Study of OncoSil, Administered to Subjects with Unresectable Locally Advanced Pancreatic Adenocarcinoma, Given in Combination with Gemcitabine or Gemcitabine+Nab-Paclitaxel Chemotherapies

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 18930

A Phase I Trial of the Combination of Lenalidomide and Blinatumomab in Patients with Relapsed or Refractory Non-Hodgkins Lymphoma (NHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19125

A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19082

A Phase I/Ib Trial of Pirfenidone Combined with Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 19089

Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (CHAMP)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19079

A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of Oprozomib in Combination with Pomalidomide and Dexamethasone in Subjects with Relapsed or Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19209

Combined Imaging and Blood Biomarkers for Breast Cancer Diagnosis

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19204

A Phase III Randomized Open-Label Multi-Center Study of Ruxolitinib vs. Best Available Therapy in Patients with Corticosteroid-Refractory Chronic Graft vs Host Disease after Allogeneic Stem Cell Transplantation (REACH 3)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19201

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Phase III Trial of the FLT3 Inhibitor Gilteritinib Administered as Maintenance Therapy Following Allogeneic Transplant for Patients with FLT3/ITD AML

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19340

Phase 2 Randomized, Double-Blinded, Controlled Study of Tucatinib vs. Placebo in Combination with Capecitabine and Trastuzumab in Patients with Pretreated Unresectable Locally Advanced or Metastatic HER2+ Breast Carcinoma (HER2CLIMB)

Cancer Type: Breast

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CLINICAL TRIAL 19341

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy of Axicabtagene Ciloleucel versus Standard of Care Therapy in Subjects with Relapsed/Refractory Diffuse Large B Cell Lymphoma (ZUMA-7)

Cancer Type: Immunotherapy

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CLINICAL TRIAL 19331

A Phase 1 Multicenter Study of KITE-585, an Autologous Anti-BCMA CAR T-Cell Therapy, in Subjects with Relapsed/Refractory Multiple Myeloma

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL 19293

Phase 1b/2 Study Of VX15/2503 In Combination With Avelumab In Advanced Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19117

A Multicenter Phase II Study of Vaccines to Prevent Recurrence in Patients with HER-2 Positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19406

Phase I/II Study of Nivolumab and Ipilimumab combined with Nintedanib in Non Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 18992

A Phase II and Pilot Trial of PD-1 Blockade with MK-3475 (Pembrolizumab) in Patients with Resectable or Unsectable Desmoplastic Melanoma (DM)

Cancer Type: Cutaneous

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CLINICAL TRIAL 19337

A Pilot Study Utilizing a HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+ Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19363

A Single-Arm, Open-Label, Multicenter Study Of Enfortumab Vedotin (ASG-22CE) For Treatment Of Patients With Locally Advanced Or Metastatic Urothelial Cancer Who Previously Received Immune Checkpoint Inhibitor (CPI) Therapy.

Cancer Type: Genitourinary

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CLINICAL TRIAL 19178

A Phase I/II Study of Concurrent Cetuximab and Nivolumab in Patients with Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Cancer Type: Head & Neck

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CLINICAL TRIAL 17773

A Phase 1 Study of the Safety and Pharmacokinetics of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects with Metastatic Urothelial Cancer and Other Malignant Solid Tumors that Express Nectin-4

Cancer Type: Genitourinary

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CLINICAL TRIAL 19392

A Dose-Ranging Study of Intravenous BNZ132-1-40 in Patients with Large Granular Lymphocyte Leukemia or Refractory Cutaneous T-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19127

A Study to Estimate the Anti-Tumor Activity and Identify Potential Predictors of Response in Patients with Advanced Mucosal or Acral Lentiginous Melanoma Receiving Standard Nivolumab in Combination with Ipilimumab Followed by Nivolumab Monotherapy

Cancer Type: Cutaneous

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CLINICAL TRIAL 19393

A Randomized, Open-Label, Phase 3 Study of Abemaciclib Combined with Standard Adjuvant Endocrine Therapy versus Standard Adjuvant Endocrine Therapy Alone in Patients with High Risk, Node Positive, Early Stage,Hormone Receptor Positive, Human Epidermal Receptor 2 Negative, Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19091

A Phase I/II Study of Pembrolizumab in Combination with Ibrutinib for Advanced, Refractory Colorectal Cancers

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19137

A Randomized Phase II Trial of Abiraterone, Olaparib, or Abiraterone + Olaparib in Patients with Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects

Cancer Type: Genitourinary

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CLINICAL TRIAL 17361

A Phase I/IB Trial of MEK162 in Combination with Erlotinib in NSCLC Harboring KRAS or EGFR Mutation

Cancer Type: Thoracic

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CLINICAL TRIAL 18752

ACTION Trial- Adoptive Cellular Therapy following Dose-Intensified Temozolomide in Newly-diagnosed Pediatric High-grade Gliomas (Phase I)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19384

A Phase 1b Multi-cohort Study of the Combination of Pembrolizumab (MK-3475) plus Binimetinib alone or the Combination of Pembrolizumab plus Chemotherapy with or without Binimetinib in Participants with Metastatic Colorectal Cancer (KEYNOTE-651)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19441

Pilot Study of Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19321

Phase I/IIA Study of the Oral 5-Azacitidine in Combination with the Histone Deacetylase Inhibitor Romidepsin for the Treatment of Patients with T-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19197

A Randomized Parallel Phase 2 Study of Elotuzumab plus Lenalidomide (Elo/Rev) for the Treatment of Serologic Relapse/Progression while on Lenalidomide Maintenance for Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18321

Phase I/Ib trial of single agent PBF-509 and in combination with PDR001 for patients with advanced NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 19367

A Pilot Study Of Intermittent Androgen Deprivation Therapy Adapted To Serum Testosterone And PSA Levels For Stage IV Castration Sensitive Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 19486

Developing and Testing an mHealth Stepped-Care Intervention for Sleep Disturbance in HCT Survivors

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19460

An Open-Label, Dose Escalation, Phase 1, First-in-Human Study of TAK-164, an Antibody-Drug Conjugate, in Patients with Advanced Gastrointestinal Cancers Expressing Guanylyl Cyclase C

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19237

An Open-Label, Single-Arm, Phase 2 Study Of Avb-620 In Women With Primary, Nonrecurrent Breast Cancer Undergoing Surgery

Cancer Type: Breast

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CLINICAL TRIAL 18858

A Phase 1/2a Open-Label Study to Determine the Safety and Tolerability of ALRN-6924 in Patients with Advanced Solid Tumors or Lymphomas Expressing Wild-Type p53 Protein

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19100

Prospective Comparative Effectiveness Trial for Malignant Bowel Obstruction

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19002

Applying mHealth to Tobacco-related Health Disparities: Enhancing Aspects of Resiliency to Aid Cessation Efforts

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19365

Phase I Trial of the LSD1 inhibitor SP-2577 in Patients with Relapsed or Refractory Ewing Sarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 18544

NSABP-RTOG-GOG (NRG) Head and Neck Cancer Bio specimen Collection Pilot Project (HNC-BCP)

Cancer Type: Head & Neck

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CLINICAL TRIAL 19511

Immune Mechanisms of Resistance to CD19 CAR T cells in Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19478

Minimally Invasive Bronchoscopic Biorepository for Lung Cancer Evaluation

Cancer Type: Thoracic

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CLINICAL TRIAL 19456

Phase III Randomized Study of Crenolanib versus Midostaurin Administered Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed Subjects with FLT3 Mutated Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19615

A Phase 1b/2, Open Label, Dose Escalation Study of MGD007, a Humanized gpA33 x CD3 DART Protein in Combination with MGA012, an Anti-PD-1 Antibody, in Patients with Relapsed or Refractory Metastatic Colorectal Carcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19407

An Open-Label, Randomized, Controlled Multi-Center Study of The Efficacy of Daromun (L19IL2 + L19TNF) Neoadjuvant Intratumoral Treatment Followed by Surgery Versus Surgery Alone in Clinical Stage IIIB/C Melanoma Patients

Cancer Type: Cutaneous

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CLINICAL TRIAL 19594

A Multicenter, Non-Randomized, Open-label Dose Escalation Phase Ib Study of Regorafenib in Combination with Pembrolizumab in Patients with Advanced Hepatocellular Carcinoma (HCC) with No Prior Systemic Therapy.

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19641

A Randomized Phase 2 Study of Cabozantinib in Combination with Nivolumab in Advanced, Recurrent Metastatic Endometrial Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19568

A Randomized Phase 2 Study of Cediranib in Combination with Olaparib versus Olaparib Alone in Men with Metastatic Castration Resistant Prostate Cancer.

Cancer Type: Genitourinary

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CLINICAL TRIAL 19580

A Phase 1/2 Dose Escalation and Dose Expansion Study of BA3011 in Patients with Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 19439

Southeast Partnership for Improving Research &Training in Cancer Health Disparities (SPIRIT-CHD): Cancer Research Education Program (CREP)

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19595

Optimizing ctDNA based MRD assessment in DLBCL patients undergoing CAR Therapy

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18979

Phase II Open-Label, Randomized Study of PARP inhibition (Olaparib) Either Alone or in Combination with Anti-PD-L1 Therapy (Atezolizumab; MPDL3280A) in Homologous DNA Repair (HDR) Deficient, Locally Advanced or Metastatic Non-HER2-positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 17971

Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)

Cancer Type: Thoracic

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CLINICAL TRIAL 19616

A Phase II, Randomized, Multi-Center, Double-Blind, Comparative Global Study to Determine the Efficacy and Safety of Durvalumab in Combination With Olaparib for First-Line Treatment in Platinum-Ineligible Patients With Unresectable Stage IV Urothelial Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 19686

A Phase 1/2a Dose Escalation and Cohort Expansion Study of the Safety, Tolerability, and Efficacy of Anti-LAG-3 Monoclonal Antibody (BMS-986016) Administered Alone and in Combination with Anti-PD-1 Monoclonal Antibody (Nivolumab, BMS-936558) in Advanced Solid Tumors

Cancer Type: Cutaneous

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CLINICAL TRIAL 19462

An Open-Label, First-in-Human, Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Maximum Tolerated Dose and / or Recommended Phase II Dose of the ATR Inhibitor BAY 1895344 in Patients with Advanced Solid Tumors and Lymphomas

Cancer Type: Multiple

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CLINICAL TRIAL 19629

A Phase 1b/2 Dose-Escalation and Cohort-Expansion Study of the Noncovalent, Reversible Brutons Tyrosine Kinase Inhibitor, SNS-062, in Patients With B-Lymphoid Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19619

Phase 1b/2 Safety, Pharmacokinetic, and Efficacy Study of G1T38 in Combination with Osimertinib in Patients with EGFR Mutation-Positive Metastatic Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 19500

Phase 1 Study Using a Plasmid DNA Coding for Emm55 Streptococcal Antigen in Patients with Unresectable Stage III or Stage IV Cutaneous Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19696

Dynamics of Gut Microbiota in Patients Treated with CD19 Chimeric Antigen Receptor (CAR) T Cell Therapy

Cancer Type: Immunotherapy

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CLINICAL TRIAL 18641

A Phase IA/IB Trial of PTX-200 and Carboplatin in Patients with Platinum-Resistant Recurrent Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19158

A Pilot Study of Atezolizumab (MPDL3280A) Following Adoptive Cell Transfer in Active Hematologic or Solid Tumor Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18989

A Phase 1b/2 Study of PV-10 Intralesional Injection in Combination with Systemic Immune Checkpoint Inhibition for Treatment of Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19693

A Randomized Phase 3 Study of Nivolumab plus Ipilimumab or Nivolumab Combined with Fluorouracil plus Cisplatin versus Fluorouracil plus Cisplatin in Subjects with Unresectable Advanced, Recurrent or Metastatic Previously Untreated Esophageal Squamous Cell Carcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19725

A Phase 1/2 Multicenter Study Evaluating the Safety And Efficacy Of Axicabtagene Ciloleucel in Combination with Utomilumab in Subjects with Refractory Large B-Cell Lymphoma (Zuma-11)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19671

A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study Comparing CB-839 in Combination with Cabozantinib (CB-Cabo) vs. Placebo with Cabozantinib (Pbo-Cabo) in Patients with Advanced or Metastatic Renal Cell Carcinoma Metastatic Renal Cell Carcinoma (RCC)

Cancer Type: Genitourinary

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CLINICAL TRIAL 19701

VISION: An International, Prospective, Open-Label, Multicenter, Randomized Phase 3 Study of 177LU-PSMA-617 in the Treatment of Patients with Progressive PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (MCRPC)

Cancer Type: Genitourinary

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CLINICAL TRIAL 19670

A Single Arm Phase II Trial of Preoperative Stereotactic Body Radiation Therapy (SBRT) for T3a or Gleason Grade Group 4 Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 19694

Phase II Study of Nivolumab and Ramucirumab for Patients with Previously-Treated Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL 19229

A Phase 1, First-in-Human, Dose Escalation Study of MGD006, a CD123 x CD3 Dual Affinity Re-Targeting (DART) Bi-Specific Antibody-Based Molecule, in Patients with Relapsed or Refractory Acute Myeloid Leukemia or Intermediate- 2/High Risk Myelodysplastic Syndrome

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18874

A Phase 1b/2 Study to Assess the Safety and Efficacy of HBI-8000 in Combination with Nivolumab in Patients with Advanced Solid Tumors Including Melanoma, Renal Cell Carcinoma (RCC) and Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Cutaneous

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CLINICAL TRIAL 18741

Randomized Embolization Trial for NeuroEndocrine Tumor Metastases To The Liver (RETNET): A Phase 3 Randomized Multicenter Trial to Compare Hepatic Progression-Free Survival Following Bland Embolization, Lipiodol Chemoembolization, and Drug-Eluting Bead Chemoembolization of Neuroendocrine Liver Metastases

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 18329

A Phase 1/2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Subjects with Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r ALL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19390

A Clinical Study to Demonstrate Safety and Efficacy of E7777 in Persistent or Recurrent Cutaneous T-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18612

A Randomized Phase II/III Study of Adjuvant Concurrent Radiation and Chemotherapy versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors

Cancer Type: Head & Neck

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CLINICAL TRIAL 18345

A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients with Advanced Solid Tumors

Cancer Type: Genitourinary

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CLINICAL TRIAL 19627

A Randomized Phase III Trial of Consolidation with Autologous Hematopoietic Cell Transplantation Followed by Maintenance Rituximab vs. Maintenance Rituximab Alone for Patients with Mantle Cell Lymphoma In Minimal Residual Disease-Negative First Complete Remission

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19466

Exploring Adherence to CDK4/6 Inhibitors among Metastatic Breast Cancer Patients

Cancer Type: Breast

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CLINICAL TRIAL 19737

S1712, " A Randomized Phase II Study of Ruxolitinib in Combination with BCR-ABL Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Patients with Evidence of Molecular Disease.- Study Chairs: Kendra Sweet, M.D., Jerald P. Radich, M.D.

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19746

A Multicenter, Open-Label, Dose Escalation Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of the DNA-PK Inhibitor M3814 in Combination with Avelumab with and without Palliative Radiotherapy in Participants with Selected Advanced Solid Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 19695

S1602: A Phase III Randomized Trial to Evaluate the Influence of BCG Strain Differences and T Cell Priming with Intradermal BCG Before Intravesical Therapy for BCG‐Naïve High‐Grade Non‐Muscle Invasive Bladder Cancer.

Cancer Type: Genitourinary

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CLINICAL TRIAL 19582

An Open-Label, Multi-Center Trial of INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination with REGN2810 in Subjects with Newly-Diagnosed Glioblastoma (GBM)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19724

Managed Access Program (MAP) To Provide Access To CTL019, For Acute Lymphoblastic Leukemia (ALL) Or Diffuse Large B-Cell Lymphoma (DLBCL) Patients With Out Of Specification Leukapheresis Product And/Or Manufactured Tisagenlecleucel Out Of Specification For Commercial Release

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19662

Phase II study of stereotactic body radiation therapy and atezolizumab in the management of recurrent, persistent, or metastatic cervical cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19683

A Phase 1, Open-Label, Multicenter, Dose-Escalation Study of RMC-4630 Monotherapy in Adult Participants with Relapsed/Refractory Solid Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 19648

Phase IB Study of Avelumab with Radiotherapy in Patients with Leptomeningeal Disease

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19681

Community Outreach: Novel Tracking of INdividuals to Understand and Assess Results (CONTINUAR)

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19740

Acute Effects of Brief Mindfulness Exercises on the Processing of Smoking Cues and Craving

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19743

A Phase 2, Multicenter, Open-Label, 2-Cohort Study Of Trastuzumab Deruxtecan (DS-8201a), An Anti-HER2 Antibody Drug Conjugate (ADC), For HER2-Over-Expressing Or -Mutated, Unresectable And/Or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 19754

A Phase 3, Randomized, Open-label Study of NKTR-214 Combined with Nivolumab Versus Nivolumab in Participants with Previously Untreated Unresectable or Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 50293

Analysis of Immune Infiltrates of Melanoma Tissue

Cancer Type: Cutaneous

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CLINICAL TRIAL 19765

Phase Ib Study of Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases

Cancer Type: Breast

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CLINICAL TRIAL 18555

A Randomized Phase II/III Trial of Prophylactic Cranial Irradiation with or without Hippocampal Avoidance for Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19622

Phase II Trial of Investigational Agents to Modulate Intermediate Endpoint Biomarkers, Including Pulmonary Nodules, in Former Smokers

Cancer Type: Thoracic

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