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CLINICAL TRIAL 17263

Phase I Trial of ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18503

STARTRK-2: An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients with Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements

Cancer Type: Thoracic

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CLINICAL TRIAL 18225

Efficacy of MBSR Treatment on Cognitive Impairment among Breast Cancer Survivors

Cancer Type: Breast

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CLINICAL TRIAL 18999

Early Detection of Cancer Progression: Leveraging Team Science

Cancer Type: Thoracic

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CLINICAL TRIAL 18975

A Phase 2 Study of REGN2810, a Fully Human Monoclonal Antibody to Programmed Death-1, in Patients with Advanced Basal Cell Carcinoma who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy

Cancer Type: Cutaneous

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CLINICAL TRIAL 18926

The National Myelodysplastic Syndromes (MDS) Study

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19341

A Phase 3, Randomized, Open-Label Study Evaluating the Efficacy of Axicabtagene Ciloleucel versus Standard of Care Therapy in Subjects with Relapsed/Refractory Diffuse Large B Cell Lymphoma (ZUMA-7)

Cancer Type: Immunotherapy

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CLINICAL TRIAL 19201

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Phase III Trial of the FLT3 Inhibitor Gilteritinib Administered as Maintenance Therapy Following Allogeneic Transplant for Patients with FLT3/ITD AML

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19339

A Phase II Trial of AZD9291 (Osimertinib) with or without Bevacizumab in Patients with EGFR Mutation Positive NSCLC and Brain Metastases

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19379

A Phase 2, Multicenter, Open-Label Study To Evaluate The Efficacy And Safety Of Luspatercept (Ace-536) In Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis And Anemia With And Without Red Blood Cell-Transfusion Dependence

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19430

Phase 1/2 Study of TEW-7197 Monotherapy in Patients with Low or Intermediate Myelodysplastic Syndromes (MDS)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19100

Prospective Comparative Effectiveness Trial for Malignant Bowel Obstruction

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19002

Applying mHealth to Tobacco-related Health Disparities: Enhancing Aspects of Resiliency to Aid Cessation Efforts

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19237

An Open-Label, Single-Arm, Phase 2 Study Of Avb-620 In Women With Primary, Nonrecurrent Breast Cancer Undergoing Surgery

Cancer Type: Breast

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CLINICAL TRIAL 19472

OsteoCool Tumor Ablation Post-Market Study (OPuS One)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19407

An Open-Label, Randomized, Controlled Multi-Center Study of The Efficacy of Daromun (L19IL2 + L19TNF) Neoadjuvant Intratumoral Treatment Followed by Surgery Versus Surgery Alone in Clinical Stage IIIB/C Melanoma Patients

Cancer Type: Cutaneous

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CLINICAL TRIAL 19630

Development of a Mindfulness-Based Treatment for the Reduction of Alcohol Use and Smoking Cessation

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 18671

Facilitating Smoking Cessation with Reduced Nicotine Cigarettes

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19622

Phase II Trial of Investigational Agents to Modulate Intermediate Endpoint Biomarkers, Including Pulmonary Nodules, in Former Smokers

Cancer Type: Thoracic

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CLINICAL TRIAL 19659

A Phase 1/2 Study of INCB053914 in Subjects With Advanced Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18844

A Phase 2 Study of Cediranib in Combination with Olaparib in Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 19722

A Phase 2, Multi-Cohort, Open-Label, Multicenter Study To Determine The Efficacy And Safety Of Bb2121 In Subjects With Relapsed And Refractory Multiple Myeloma And In Subjects With High-Risk Multiple Myeloma Having Progressed Within One Year Of Initial Treatment

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19654

A Phase 1 Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Doses and Treatment Intensification of a Vaccine-Based Immunotherapy Regimen-2 (VBIR-2) (PF-06936308) for Advanced Non-Small Cell Lung Cancer and Metastatic Triple-Negative Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19637

A Prospective Randomized Study of a Personalized Approach to the Inpatient Management of Hospitalized Oncology Patients with Hyperglycemia

Cancer Type: Multiple

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CLINICAL TRIAL 19199

Phase II Trial of Ibrutinib and PD-1 Blockade in High Risk Chronic Lymphocytic Leukemia to Improve Immune Function.

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18874

A Phase 1b/2 Study to Assess the Safety and Efficacy of HBI-8000 in Combination with Nivolumab in Patients with Advanced Solid Tumors Including Melanoma, Renal Cell Carcinoma (RCC) and Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Cutaneous

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CLINICAL TRIAL 20362

A Phase 3, International, Multi-center, Randomized, Double-blind, Placebo- controlled Clinical Trial to Study the Efficacy, Immunogenicity, and Safety of the 9vHPV Vaccine, a Multivalent L1 Virus-like Particle Vaccine, in the Prevention of Oral Persistent Infection with HPV Types 16, 18, 31, 33, 45, 52, or 58 in Adult Males, 20 to 45 Years of Age

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19856

A Phase III Randomised, Double-Blind, Placebo-Controlled,Multicentre Study of Durvalumab in Combination with Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib in Newly Diagnosed Advanced Ovarian Cancer Patients (DUO-O).

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20096

Composite Health Assessment Model for Older Adults: Applying Pre-transplant Comorbidity, Geriatric Assessment, and Biomarkers to Predict Non-Relapse Mortality after Allogeneic Transplantation (CHARM)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19197

A Randomized Parallel Phase 2 Study of Elotuzumab plus Lenalidomide (Elo/Rev) for the Treatment of Serologic Relapse/Progression while on Lenalidomide Maintenance for Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20048

Cervical Cancer: PROGRESS for Prevention

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 20479

Efficacy of SOAR (Survivors Overcoming and Achieving Resiliency) Survivorship Workshop for Breast Cancer Survivors

Cancer Type: Breast

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CLINICAL TRIAL 20056

Phase II Clinical Trial of Green Tea Catechins in Men on Active Surveillance (AS)

Cancer Type: Genitourinary

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CLINICAL TRIAL 20156

Mindfulness in AYA Patients Undergoing Hematopoietic Stem Cell Transplantation: A Pilot Proposal

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL 20498

Immune Checkpoint Blockade for Kidney Transplant Recipients with Selected Unresectable or Metastatic Cancers

Cancer Type: Cutaneous

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CLINICAL TRIAL 19706

A Phase II Biomarker Trial of Avadomide (CC-122) in Combination with Nivolumab in Advanced Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 18321

Phase I/Ib trial of single agent PBF-509 and in combination with PDR001 for patients with advanced NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 19719

A Phase Ib, Multicenter Study To Determine The Safety And Tolerability of Tisagenlecleucel in Combination with Ibrutinib in Adult Patients With Relapsed and/or Refractory Diffuse Large B-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19813

A Phase 3, Multicenter, Randomized, Open Label Study to Compare the Efficacy and Safety of BB2121 Versus Standard Triplet Regimens in Subjects with Relapsed and Refractory Multiple Myeloma (Rrmm) (Karmma-3)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19988

A Phase II Open Label, Study of IMMU-132 in Metastatic Urothelial Cancer After Failure of Platinum-Based Regimen or Anti-PD-1/ PD-L1 Based Immunotherapy

Cancer Type: Genitourinary

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CLINICAL TRIAL 20015

Change in Relative Cerebral Blood Volume as a Biomarker for Early Response to Bevacizumab in Patients with Recurrent Glioblastoma

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19872

A Phase 3, Open-Label, Randomized Study To Compare The Efficacy And Safety Of Luspatercept (Ace-536) Versus Epoetin Alfa for the Treatment Of Anemia Due To IPSS-R Very Low, Low Or Intermediate Risk Myelodysplastic Syndromes (Mds) In Esa Naïve Subjects Who Require Red Blood Cell Transfusions The Commands Trial

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20028

Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19729

SOLAR: A Phase 2, Randomized, Open-label, Parallel-group, Active Comparator, Multi-center Study to Investigate the Efficacy and Safety of Cobomarsen (MRG-106) in Subjects with Cutaneous T-Cell Lymphoma (CTCL), Mycosis Fungoides (MF) Subtype

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20054

A Phase 1 Study of AG-636 in the Treatment of Subjects With Advanced Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20019

Ramucirumab Plus Irinotecan in Patients with Previously Treated Advanced Gastric or Gastro-Esophageal Junction Adenocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19943

Somatostatin receptor expression in poorly-differentiated neuroendocrine carcinomas of the GI tract: analysis using 68Ga-dotatate PET scan

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 18782

A Pilot Study Of NY-ESO-1c259T Cells In Subjects With Advanced Myxoid/ Round Cell Liposarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 19836

REPLATINUM: A Phase 3, Controlled, Open-label,Randomized Study of RRx-001 Administered Sequentially with a Platinum Doublet or a Platinum Doublet in Third-Line or Beyond Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 20022

Feasibility Study for Electroacupuncture for Chemotherapy- Induced Peripheral Neuropathy (CIPN) Using a Point-Of-Nerve Conduction Device (NeuroMetrix) and the Rydel-Seiffer Tuning Fork

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20007

Utilizing Augmented Reality as an Adjunct for Smoking Cessation; Development and Initial Validation

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 18621

A Phase 1/2 Study of Talimogene laherparepvec in Combination with Neoadjuvant Chemotherapy in Triple Negative Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19421

A Phase 3, Randomized, Single Dose, Open-Label Study to Investigate the Safety and Efficacy of OTL38 Injection (OTL38) for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 18915

A Phase 1 Trial of MLN0128 (TAK-228) in Combination with Osimertinib (AZD9291) in Advanced EGFR Mutation Positive Non-Small Cell Lung Cancer (NSCLC) After Progression on a Previous EGFR Tyrosine Kinase Inhibitor

Cancer Type: Thoracic

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CLINICAL TRIAL 19363

A Single-Arm, Open-Label, Multicenter Study Of Enfortumab Vedotin (ASG-22CE) For Treatment Of Patients With Locally Advanced Or Metastatic Urothelial Cancer Who Previously Received Immune Checkpoint Inhibitor (CPI) Therapy.

Cancer Type: Genitourinary

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CLINICAL TRIAL 19803

A Phase II Trial With Safety Run-In Of Neoadjuvant Therapy With An Aromatase Inhibitor In Combination With Durvalumab (Medi4736) In Postmenopausal Patients With Hormone-Receptor-Positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19742

Phase 1/1b Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19500

Phase 1 Study Using a Plasmid DNA Coding for Emm55 Streptococcal Antigen in Patients with Unresectable Stage III or Stage IV Cutaneous Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19825

A Phase III Multicenter, Randomized, Open Label Study of APR-246 in Combination with Azacitidine Versus Azacitidine Alone for the Treatment of TP53 Mutant Myelodysplastic Syndromes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19801

An Adaptive Phase I/II Dose Escalation Trial of Stereotactic Body Radiation Therapy in Combination with Radiomodulating Agent Gc4419 in Locally Advanced Pancreatic Adenocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 17969

Randomized Study of Erlotinib vs. Observation in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 19939

A Randomized, Open-Label, Phase 1-2 Study of ASTX727 Low Dose (ASTX727 LD) Extended Schedule in Subjects with Lower Risk (IPSS Low or Intermediate-1) Myelodysplastic Syndromes (MDS)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19837

Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients with Soft Tissue Sarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 18891

A Multinational Open-Label, Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Administrations of NKR-2 in Patients with Different Metastatic Tumor Types

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19296

A Randomized, Double-blind, Placebo-controlled Study of 4-hydroxytamoxifen Topical Gel in Women with Mammographically Dense Breast

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19611

The Effect of Acute Interpersonal Racial Discrimination on Smoking Motivation and Behavior among Black Smokers

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19685

Phase II Toxicity Study of Pleurectomy/Decortication, (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients with Locally Advanced Malignant Pleural Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL 18555

A Randomized Phase II/III Trial of Prophylactic Cranial Irradiation with or without Hippocampal Avoidance for Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19720

A Phase II, Single Arm, Multicenter Open Label Trial to Determine the Efficacy and Safety of Tisagenlecleucel (CTL019) In Adult Patients with Refractory or Relapsed Follicular Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20026

A Phase I/II Study of NBTXR3 Activated by SABR for Patients with Advanced HNSCC or NSCLC Treated with an Anti-PD-1 Antibody

Cancer Type: Thoracic

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CLINICAL TRIAL 20039

An Open-Label, Phase I/II Study to Assess the Safety and Clinical Activity of NKR-2 Treatment Administration after a Non-Myeloablative Preconditioning Chemotherapy in Relapse/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients.

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20348

Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III randomized study of chemoradiation versus chemoradiation plus Atezolizumab

Cancer Type: Thoracic

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CLINICAL TRIAL 19748

Phase II Randomized Trial of Radiotherapy with Concurrent and Adjuvant Pembrolizumab (Keytruda®) Versus Concurrent Chemotherapy in Patients with Advanced/Intermediate-Risk p16+ Head and Neck Squamous Cell Carcinoma (KEYCHAIN Trial)

Cancer Type: Head & Neck

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CLINICAL TRIAL 19662

Phase II study of stereotactic body radiation therapy and atezolizumab in the management of recurrent, persistent, or metastatic cervical cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19727

A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of Ruxolitinib for the treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18959

A Phase 2 Study to Evaluate the Safety, Tolerability and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-145) followed by IL-2 in Patients with Recurrent and/or Metastatic Cervical Carcinoma

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 18346

Evaluating the Safety and Biological Activity of a Dendritic Cell Survivin Vaccine in Patients with Multiple Myeloma Undergoing Autologous Hematopoietic Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19477

A Phase II study of TAS 102 in Combination with Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19302

A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-033, an anti-LAG-3 Monoclonal Antibody, alone and in combination with an anti-PD-1 in Patients with Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 20297

Cabozantinib plus Pembrolizumab as First-Line Therapy for Cisplatin-Ineligible Advanced Urothelial Carcinoma (PemCab)

Cancer Type: Genitourinary

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CLINICAL TRIAL 19820

A Phase 1 Study Exploring the Safety, Tolerability, Pharmacokinetics,and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 14690

Total Cancer Care Protocol: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer

Cancer Type: Cancer Control

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CLINICAL TRIAL 16933

Older Breast Cancer Patients: Risk For Cognitive Decline

Cancer Type: Breast

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CLINICAL TRIAL 16028

Transdisciplinary Research in Colorectal Cancer: The ColoCare Study

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 16480

Radiomics: A Prospective Study of Outcome in Lung Cancer

Cancer Type: Multiple

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CLINICAL TRIAL 19203

Reduced Intensity Conditioning for Haploidentical Bone Marrow Transplantation in Patients with Symptomatic Sickle Cell Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18494

A Phase I/II Study of Pembrolizumab and Vorinostat in Patients with Immune Therapy Naïve and Immune Therapy Pretreated Stage IV NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 19082

A Phase I/Ib Trial of Pirfenidone Combined with Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 17268

I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2)

Cancer Type: Breast

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CLINICAL TRIAL 19072

A Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma (iNHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19089

Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (CHAMP)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19181

Patient-Reported Outcomes in Immunotherapy for Head and Neck Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 18828

Smartphone-Based Assessment of Patient-Reported Outcomes Related to Receipt of Immunotherapy

Cancer Type: Head & Neck

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CLINICAL TRIAL 19209

Combined Imaging and Blood Biomarkers for Breast Cancer Diagnosis

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 18979

Phase II Open-Label, Randomized Study of PARP inhibition (Olaparib) Either Alone or in Combination with Anti-PD-L1 Therapy (Atezolizumab; MPDL3280A) in Homologous DNA Repair (HDR) Deficient, Locally Advanced or Metastatic Non-HER2-positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19456

Phase III Randomized Study of Crenolanib versus Midostaurin Administered Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed Subjects with FLT3 Mutated Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18786

A Phase 2, Randomized, Multi-institutional Study of Nivolumab and Ipilimumab versus Nivolumab, Ipilimumab and Stereotactic Body Radiation Therapy for Metastatic Merkel Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19387

A Phase 2 Study of Poziotinib in Patients with Non-Small Cell Lung Cancer, (NSCLC), Locally Advanced or Metastatic, with EGFR or HER2 Exon 20 Insertion Mutation (ZENITH20)

Cancer Type: Thoracic

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CLINICAL TRIAL 19629

A Phase 1b/2 Dose-Escalation and Cohort-Expansion Study of the Noncovalent, Reversible Brutons Tyrosine Kinase Inhibitor, SNS-062, in Patients With B-Lymphoid Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19360

Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant (ASCENT): A Phase 2 Trial of Induction, Consolidation and Maintenance in Subjects with High Risk Smoldering Multiple Myeloma (SMM)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 17971

Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)

Cancer Type: Thoracic

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CLINICAL TRIAL 19462

An Open-Label, First-in-Human, Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Maximum Tolerated Dose and / or Recommended Phase II Dose of the ATR Inhibitor BAY 1895344 in Patients with Advanced Solid Tumors and Lymphomas

Cancer Type: Multiple

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CLINICAL TRIAL 19578

Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients

Cancer Type: Multiple

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CLINICAL TRIAL 19691

Adjuvant Therapy with Pembrolizumab versus Placebo in Resected High-Risk Stage II Melanoma: A Randomized, Double-Blind Phase 3 Study (Keynote 716)

Cancer Type: Cutaneous

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CLINICAL TRIAL 19737

S1712, " A Randomized Phase II Study of Ruxolitinib in Combination with BCR-ABL Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Patients with Evidence of Molecular Disease.- Study Chairs: Kendra Sweet, M.D., Jerald P. Radich, M.D.

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19646

Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III

Cancer Type: Breast

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CLINICAL TRIAL 18906

A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an anti-TIM-3 Monoclonal Antibody, in Patients with Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 19754

A Phase 3, Randomized, Open-label Study of NKTR-214 Combined with Nivolumab Versus Nivolumab in Participants with Previously Untreated Unresectable or Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19743

A Phase 2, Multicenter, Open-Label, 2-Cohort Study Of Trastuzumab Deruxtecan (DS-8201a), An Anti-HER2 Antibody Drug Conjugate (ADC), For HER2-Over-Expressing Or -Mutated, Unresectable And/Or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 19721

A Phase 2 Multicenter Study Evaluating the Efficacy and Safety of Axicabtagene Ciloleucel as First-Line Therapy in Subjects with High-Risk Large B-Cell Lymphoma (ZUMA-12)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19717

The Florida Pancreas Collaborative Next-Generation Biobank: Reducing Health Disparities and Improving Survival for Pancreatic Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19681

Community Outreach: Novel Tracking of INdividuals to Understand and Assess Results (CONTINUAR)

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19961

A Phase 1B/2 Study To Evaluate The Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of Eq001 In Subjects With Newly Diagnosed Acute Graft Versus Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19942

Sequential Maintenance with Thoracic Radiotherapy and Durvalumab (MEDI4736) monotherapy or Durvalumab (MEDI 4736) Combinations (Tremelimumab or Olaparib) in Patients with Extensive Stage-Small Cell Lung Cancer after First Line Platinum Based Chemotherapy

Cancer Type: Thoracic

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CLINICAL TRIAL 18630

Phase 1/2 Investigator Sponsored Study of Selinexor in Combination with High-Dose Melphalan Before Autologous Hematopoietic Cell Transplantation for Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20003

LungMAP: A Master Protocol to Evaluate Biomarker-Driven Therapies And Immunotherapies In Previously-Treated Non-Small Cell Lung Cancer(Lung-MAP Screening Study)

Cancer Type: Thoracic

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CLINICAL TRIAL 19960

A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmacodynamics of ALLO-501, an Anti-Cd19 Allogeneic Car T Cell Therapy in Patients with Relapsed/Refractory Large B-Cell and Follicular Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19829

A Phase 1/2a, Open-label, Dose-escalation, Dose-expansion, Parallel Assignment Study to Evaluate the Safety and Clinical Activity of PBCAR0191 in Subjects with Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18992

A Phase II and Pilot Trial of PD-1 Blockade with MK-3475 (Pembrolizumab) in Patients with Resectable or Unsectable Desmoplastic Melanoma (DM)

Cancer Type: Cutaneous

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CLINICAL TRIAL 19733

Motivating a Spectrum of Cancer Patients to Quit Smoking: Intervention Development and Feasibility

Cancer Type: Multiple

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CLINICAL TRIAL 19954

IMPACT: Immunotherapy in Patients with Metastatic Cancers and CDK12 Mutations

Cancer Type: Genitourinary

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CLINICAL TRIAL 18936

A Phase I-II Study of Interferon-gamma Plus Weekly Paclitaxel, Trastuzumab and Pertuzumab in Patients with HER-2 Positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 18811

Randomized, Double-Blind, Phase 2/3 Study in Subjects with Malignant Pleural Mesothelioma with Low Argininosuccinate Synthetase 1 Expression to Assess ADI-PEG 20 with Pemetrexed and Cisplatin (ATOMIC-Meso Phase 2/3 Study)

Cancer Type: Thoracic

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CLINICAL TRIAL 19953

A Phase 3, Open-Label, Randomized, Parallel Group Study to Evaluate the Efficacy and Safety of Intrapleural Administration of Adenovirus-Delivered Interferon Alpha-2b (rAd-IFN) in Combination with Celecoxib and Gemcitabine in Patients with Malignant Pleural Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL 20036

Phase II trial of APR-246 in combination with azacitidine as maintenance therapy for TP53 mutated AML or MDS following allogeneic stem cell transplant

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19158

A Pilot Study of Atezolizumab (MPDL3280A) Following Adoptive Cell Transfer in Active Hematologic or Solid Tumor Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19683

A Phase 1, Open-Label, Multicenter, Dose-Escalation Study of RMC-4630 Monotherapy in Adult Participants with Relapsed/Refractory Solid Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 20038

Phase I Dose-Escalation and Dose-Expansion Trial of a Novel Glutaminase Inhibitor (CB-839 HCl) in Combination with Carfilzomib and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19958

Phase I/II Study of Dabrafenib, Trametinib, and Navitoclax in BRAF Mutant Melanoma (Phase I and II) and Other Solid Tumors (Phase I only)

Cancer Type: Cutaneous

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CLINICAL TRIAL 20040

A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 18523

A Validation Study on the Impact of Decipher® Testing on Treatment Recommendations in African-American and Non-African American Men with Prostate Cancer (VANDAAM Study)

Cancer Type: Genitourinary

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CLINICAL TRIAL 18331

Selection of Allogeneic Hematopoietic Cell Donors Based on KIR and HLA Genotypes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18744

A Phase I Trial of MEDI-570 in Patients with Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL) Follicular Variant and Angioimmunoblastic T-Cell Lymphoma (AITL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18386

A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL 18847

Increasing HPV Vaccination Series Completion Rates among Adolescent Hispanics in Tampa and Ponce

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 17970

A Randomized Phase III Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Observation for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

Cancer Type: Thoracic

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CLINICAL TRIAL 17716

A Biomarker-related Approach to Screening for HPV-related Oropharyngeal Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 18569

A Single-arm, Multi-Center, Open-Label Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Melphalan/HDS Treatment in Patients with Hepatic-Dominant Ocular Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 17723

Expansion of Enduring Infrastructure to Support Lung Cancer Screening Research

Cancer Type: Thoracic

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CLINICAL TRIAL 19322

A Phase 1b Trial of Hu5F9-G4 Monotherapy or Hu5F9-G4 in Combination with Azacitidine in Patients with Hematological Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18994

Phase II Randomized Trial of Radiotherapy with or without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) with TP53 Sequencing

Cancer Type: Head & Neck

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CLINICAL TRIAL 18752

ACTION Trial- Adoptive Cellular Therapy following Dose-Intensified Temozolomide in Newly-diagnosed Pediatric High-grade Gliomas (Phase I)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19327

A Phase 2 Trial of Pembrolizumab Plus Bevacizumab in Patients with Metastatic Melanoma or Non-small Cell Lung Cancer with Untreated Brain Metastases

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19194

A Phase 1 Study of bb21217, an anti-BCMA CAR T Cell Drug Product, in Relapsed and/or Refractory Multiple Myeloma

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL 19319

InPACT- International Penile Advanced Cancer Trial (International Rare Cancers Initiative study)

Cancer Type: Genitourinary

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CLINICAL TRIAL 19486

Developing and Testing an mHealth Stepped-Care Intervention for Sleep Disturbance in HCT Survivors

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19501

Project ACTS (Adherence to CT Screening): Development and Usability of Patient Engagement Tools to Support Lung Cancer Screening Adherence

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19365

Phase I Trial of the LSD1 inhibitor SP-2577 in Patients with Relapsed or Refractory Ewing Sarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 19627

A Randomized Phase III Trial of Consolidation with Autologous Hematopoietic Cell Transplantation Followed by Maintenance Rituximab vs. Maintenance Rituximab Alone for Patients with Mantle Cell Lymphoma In Minimal Residual Disease-Negative First Complete Remission

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18741

Randomized Embolization Trial for NeuroEndocrine Tumor Metastases To The Liver (RETNET): A Phase 3 Randomized Multicenter Trial to Compare Hepatic Progression-Free Survival Following Bland Embolization, Lipiodol Chemoembolization, and Drug-Eluting Bead Chemoembolization of Neuroendocrine Liver Metastases

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19647

A Randomized, Phase II Study of Ficlatuzumab with or without Cetuximab in Patients with Cetuximab-Resistant, Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Cancer Type: Head & Neck

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CLINICAL TRIAL 19584

A Phase 2, Open-Label, 2-Cohort, Multicenter Study of INCB050465, a PI3Kä Inhibitor, in Relapsed or Refractory Mantle Cell Lymphoma Previously Treated With or Without a BTK Inhibitor (CITADEL-205)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19725

A Phase 1/2 Multicenter Study Evaluating the Safety And Efficacy Of Axicabtagene Ciloleucel in Combination with Utomilumab in Subjects with Refractory Large B-Cell Lymphoma (Zuma-11)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19479

A Phase 1-2 Study of the Combination of Olaparib and Tremelimumab in BRCA1 and BRCA2 Mutation Carriers with Recurrent Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 18345

A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients with Advanced Solid Tumors

Cancer Type: Genitourinary

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CLINICAL TRIAL 18612

A Randomized Phase II/III Study of Adjuvant Concurrent Radiation and Chemotherapy versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors

Cancer Type: Head & Neck

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CLINICAL TRIAL 19495

A Multicenter, Randomized, Double Blinded, Placebo Controlled, Phase 3 trial of Adjuvant Avelumab (anti PDL1 antibody) in Merkel Cell Carcinoma Patients with Clinically Detected Lymph Node Metastases

Cancer Type: Cutaneous

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CLINICAL TRIAL 18778

A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19680

Phase II Multicenter Trial of Panitumumab, Nivolumab, and Ipilimumab for KRAS/NRAS/BRAF Wild-Type MSS Refractory Metastatic Colorectal Adenocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19878

A Phase II Study of Talimogene Laherparepvec (T-VEC) in the Treatment of Locally Advanced Cutaneous Angiosarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 19936

Maintenance Systemic Therapy versus Local Consolidative Therapy (Lct) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (Nsclc): A Randomized Phase II/III Trial

Cancer Type: Genitourinary

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CLINICAL TRIAL 19962

A Phase 1 Study Evaluating the Safety and Efficacy of HPV16 E7 T Cell Receptor Engineered T Cells (KITE-439) in HLA-A*02:01+Subjects with Relapsed/Refractory HPV16+ Cancers

Cancer Type: Head & Neck

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CLINICAL TRIAL 19967

A Phase I, Multi-Center, Open-Label, Treatment Duration Increment, Expansion, Safety, and Pharmacodynamic Study of CX-4945 Administered Orally Twice Daily to Patients with Advanced Basal Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19940

A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients with Recurrent Small Cell Lung Cancer: Big Ten Cancer Research Consortium BTCRC-LUN17-127

Cancer Type: Thoracic

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CLINICAL TRIAL 19874

Phase Ib Feasibility Trial of Neoadjuvant Nivolumab/Lirilumab in Cisplatin-Ineligible Muscle-Invasive Bladder Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 19948

A Phase 2 Study of Atezolizumab and Cobimetinib in PD-1/PD-L1 Inhibitor Resistant or Refractory Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19473

Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Stage III-IVB Head and Neck Cancer with a Contraindication to Cisplatin

Cancer Type: Head & Neck

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CLINICAL TRIAL 19070

Multicenter, Open-Label, Expanded Access Study of Axicabtagene Ciloleucel or the Treatment of Subjects with Relapsed/Refractory Large B-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18938

A Phase 1 Study Evaluating the Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*0401 Positive Subjects with Advanced Cancers

Cancer Type: Multiple

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CLINICAL TRIAL 19656

Phase I Study of Ceritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 19818

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Cabozantinib (XL184) in Subjects with Radioiodine-Refractory Differentiated Thyroid Cancer Who Have Progressed after Prior VEGFR-Targeted Therapy

Cancer Type: Head & Neck

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CLINICAL TRIAL 19406

Phase I/II Study of Nivolumab and Ipilimumab combined with Nintedanib in Non Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19777

A Phase II Randomized Study of Nivolumab (NSC-748726) with Ipilimumab (NSC-732442) OR Ipilimumab Alone in Advanced Melanoma Patients Refractory to an Anti-PD-1 or Anti-PD-L1 Agent

Cancer Type: Cutaneous

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CLINICAL TRIAL 19877

A Randomized Phase 2 Study of CDX-1127 (Varlilumab) in Combination with Nivolumab in Patients with Relapsed or Refractory Aggressive B-Cell Lymphomas

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19883

Phase 2 Study of ZW25 Plus First-line Combination Chemotherapy in HER2-Expressing Gastroesophageal Adenocarcinoma (GEA)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19715

An Open-Label, Randomized, Multicenter, Phase Ib/II Trial Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Mosunetuzumab (Btct4465a) In Combination With Polatuzumab Vedotin In Patients With B-Cell Non-Hodgkin Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19692

A Prospective, Randomised, Controlled, Open-label, Multicentre Phase III Study to Evaluate Efficacy and Safety of Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-Edotreotide Compared to Targeted Molecular Therapy with Everolimus in Patients with Inoperable, Progressive, Somato-Statin Receptor-Positive (SSTR+), Neuroendocrine Tumours of Gastroenteric or Pancreatic Origin (GEP-NET).

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19125

A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19570

A Phase II Trial of Pembrolizumab and Cabozantinib in Patients with RM SCCHN

Cancer Type: Head & Neck

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CLINICAL TRIAL 19487

A Phase Ib/II Study to Evaluate the Safety, Feasibility and Efficacy of Nivolumab or Nivolumab in Combination with Azacitidine in Patients with Recurrent, Resectable Osteosarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 20027

A Phase III Trial of Stereotactic Radiosurgery Compared with Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5-15 Brain Metastases

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 18304

A Phase II Trial of AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19694

Phase II Study of Nivolumab and Ramucirumab for Patients with Previously-Treated Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL 19855

The AIM-HN and SEQ-HN Study: A 2 Cohort, Non-comparative, Pivotal Study Evaluating the Efficacy of Tipifarnib in Patients with Head and Neck Squamous Cell Carcinoma(HNSCC) with HRAS Mutations (AIM-HN) and the Impact of HRAS Mutations on Response to First Line Systemic Therapies for HNSCC (SEQ-HN).

Cancer Type: Head & Neck

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CLINICAL TRIAL 18944

A Phase 2 Study to Evaluate the Safety, Tolerability and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-145) followed by IL-2 in Patients with Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck

Cancer Type: Head & Neck

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CLINICAL TRIAL 19178

A Phase I/II Study of Concurrent Cetuximab and Nivolumab in Patients with Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

Cancer Type: Head & Neck

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CLINICAL TRIAL 19860

EL CENTRO: Engaging Latinos in the Center of Cancer Treatment Options - RCT of Usual Chemotherapy Educational Tools versus Investigational Chemotherapy Educational Tools

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20087

A Randomized, Double-Blind, Phase 3 Trial Of Maintenance With Selinexor/Placebo After Combination Chemotherapy For Patients With Advanced Or Recurrent Endometrial Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19435

Combination of Nivolumab Immunotherapy with Radiation Therapy and Androgen Deprivation Therapy in the Management of Gleason Group 5 Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 19389

A Phase 1, First-in-Human, Open-Label, Dose Escalation Study of JNJ-61186372, a Human Bispecific EGFR and cMet Antibody, in Subjects with Advanced Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19648

Phase IB Study of Avelumab with Radiotherapy in Patients with Leptomeningeal Disease

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20081

Patterns of Cannabis Use in Young Adult Cancer Patients

Cancer Type: Multiple

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CLINICAL TRIAL 20041

A Randomized, Multicenter, Phase III Trial of Tacrolimus/Methotrexate versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19093

Open-Label Randomized Pilot Study to Assess the Safety, Tolerability and Antitumor Activity of Genetically Engineered NY-ESO-1 Specific (c259) T Cells Alone or in Combination with Pembrolizumab in HLA-A2+ Subjects with NY-ESO-1 and/or LAGE-1a Positive Relapsed and Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19981

A Randomized Phase II Study of Atezolizumab (MPDL3280A) plus Recombinant Human IL-7 (CYT107) in patients with locally advanced or metastatic urothelial carcinoma

Cancer Type: Genitourinary

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CLINICAL TRIAL 19802

A Phase 1/2 Feasibility And Safety Study Of PSCA-Specific Chimeric Antigen Receptor Engineered T Cells (BPX-601) In Subjects With Non-Resectable Pancreatic Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20069

A Phase 1, Multi-center, Open-label, Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of an Orally Available Small Molecule CC-99282 Alone and in Combination with Rituximab in Subjects with Relapsed and/or Refractory Diffuse Large B Cell Lymphoma (R/R DLBCL) and Indolent Non-Hodgkin Lymphoma (R/R iNHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19724

Managed Access Program (MAP) To Provide Access To CTL019, For Acute Lymphoblastic Leukemia (ALL) Or Diffuse Large B-Cell Lymphoma (DLBCL) Patients With Out Of Specification Leukapheresis Product And/Or Manufactured Tisagenlecleucel Out Of Specification For Commercial Release

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19952

A Multi-center Phase II Study of CC486-CHOP in Patients with Previously Untreated Peripheral T-cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20030

A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19776

A Phase 1/2 Dose Escalation and Dose Expansion Study of BA3021 in Patients with Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 20163

EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non©\Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNature©\driven Analysis

Cancer Type: Thoracic

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CLINICAL TRIAL 20050

QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination with ALT-803 in Patients with BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 18783

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19491

The IRX-2 Regimen Combined with Nivolumab in Recurrent/Metastatic Solid Tumors: A Phase 1b Study to Evaluate the Safety, Determine Recommended Phase 2 Dose (RP2D), and Investigate the Biologic and Clinical Activity

Cancer Type: Multiple

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CLINICAL TRIAL 20137

A Phase 2 Open-Label, Single-Arm Study To Evaluate the Efficacy and Safety of the Combination OF Niraparib and TSR-042 in Patients with Platinum-Resistant Ovarian Cancer (MOONSTONE)

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20126

Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (CTRL-ALT-D)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20068

A Randomized, Placebo-Controlled, Double-Blind Study of Adjuvant Cemiplimab Versus Placebo After Surgery and Radiation Therapy in Patients With High Risk Cutaneous Squamous Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20149

A Phase 1/2, Open-Label, Multi-Center, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity of TPX-0005 in Patients with Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements (TRIDENT-1)

Cancer Type: Thoracic

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CLINICAL TRIAL 20052

ULTRA-V: Phase 2 Study to Assess the Efficacy and Safety of Ublituximab in Combination with Umbralisib and Venetoclax (U2-V) in Subjects with Chronic Lymphocytic Leukemia (CLL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20178

An Open-Label Randomized Phase II Study of Combining Osimertinib with and without Ramucirumab in TKI-naïve EGFR-mutant Locally Advanced or Metastatic NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 20098

A Phase 3 Study of Pembrolizumab in Combination with Pemetrexed/Platinum (Carboplatin or Cisplatin) Followed by Pembrolizumab and Maintenance Olaparib vs Maintenance Pemetrexed in the First-Line Treatment of Participants with Metastatic Nonsquamous Non-Small-Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19732

Randomized, Double-Blinded Phase III Study of Cabozantinib Versus Placebo in Patients with Advanced Neuroendocrine Tumors after Progression on Everolimus (Cabinet)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19686

A Phase 1/2a Dose Escalation and Cohort Expansion Study of the Safety, Tolerability, and Efficacy of Anti-LAG-3 Monoclonal Antibody (BMS-986016) Administered Alone and in Combination with Anti-PD-1 Monoclonal Antibody (Nivolumab, BMS-936558) in Advanced Solid Tumors

Cancer Type: Cutaneous

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CLINICAL TRIAL 20171

A Phase 1/2, Open-label, Dose Escalation, and Cohort Expansion Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of ARV-471 in Patients with ER+/HER2- Locally Advanced or Metastatic Breast Cancer, Who Have Received Prior Hormonal Therapy and Chemotherapy in the Locally Advanced/Metastatic Setting

Cancer Type: Breast

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CLINICAL TRIAL 18964

Randomized Double-Blind Phase III Study of Ibrutinib During and Following Autologous Stem Cell Transplantation Versus Placebo in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma of the Activated B-cell Subtype

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19601

A Randomized, Double-Blind Phase 2/3 Study of Relatlimab Combined with Nivolumab versus Nivolumab in Participants with Previously Untreated Metastatic or Unresectable Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20099

A Phase 3 Study of Pembrolizumab in Combination with Carboplatin/Taxane (Paclitaxel or Nab-paclitaxel) Followed by Pembrolizumab with or without Maintenance Olaparib in the First-line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 20168

HORMONET: Phase II Study of Hormone Therapy with Tamoxifen in Patients with well Differentiated Neuroendocrine Tumors and Hormone Receptor Positive Expression

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20017

A Randomized Phase 2 Study of Bevacizumab and Either Weekly Anetumab Ravtansine or Weekly Paclitaxel in Platinum-Resistant or Platinum Refractory Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19704

Radiation and Chemotherapy with Ipilimumab followed by Nivolumab for Patients with Stage III Unresectable NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 19150

A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 and TGR-1202 alone in Patients A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 With or Without Bendamustine and TGR-1202 Alone in Patients With Previously Treated Non-Hodgkin's Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19989

Targeted Intra-arterial Gemcitabine vs. Continuation of IV Gemcitabine plus Nab-Paclitaxel following Induction with sequential IV Gemcitabine plus Nab-Paclitaxel and Radiotherapy for Locally Advanced Pancreatic Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19974

Contrast-Enhanced Ultrasound for the Evaluation of Changes in Tumor Blood Flow and the Surrounding Hepatic Parenchyma before, during and after Hepatic Artery Embolization

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19850

A Phase 3, Randomized, Study of Neoadjuvant Chemotherapy alone versus Neoadjuvant Chemotherapy plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Post-Surgery Therapy with Nivolumab or Nivolumab and BMS-986205 in Participants with Muscle-Invasive Bladder Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 20070

A Phase 3, Randomized, Double-blind Trial of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (KEYNOTE-641)

Cancer Type: Genitourinary

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CLINICAL TRIAL 20253

Open Label, Multi-Center, Phase 1b Clinical Trial to Evaluate the Safety and Efficacy of Autologous CAR-BCMA T cells (CT053) in Patients With Relapsed and/or Refractory Multiple Myeloma

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL 19956

A Phase 1b Trial of CB-839 in Combination with Radiation Therapy and Temozolomide in Patients with IDH-mutated Diffuse Astrocytoma and Anaplastic Astrocytoma

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20166

A Phase II Study Evaluating Safety and Efficacy of Niraparib in Patients with Previously Treated Homologous Recombination (HR) Defective or Loss of Heterozygosity (LOH) high Metastatic Esophageal/Gastroesophageal Junction/Proximal Gastric Adenocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20173

A Phase 2, Multi-arm, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of IPI-549 Administered in Combination with Front-line Treatment Regimens in Patients with Locally Advanced and/or Metastatic Triple-Negative Breast Cancer or Renal Cell Carcinoma

Cancer Type: Breast

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CLINICAL TRIAL 19414

A Phase 2 Study of Talimogene Laherparepvec (T-VEC) and Radiation in Localized Soft Tissue Sarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 20130

Phase II Study of Daratumumab Based Response Adapted Therapy for Older Adults with Newly Diagnosed Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19579

Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy Fractionation for Patients with HPV+ Oropharyngeal Cancers.

Cancer Type: Head & Neck

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CLINICAL TRIAL 19377

A Phase 1b/2 Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of AMG 592 in Adult Subjects With Steroid Refractory Chronic Graft versus Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20078

A Phase 3, Randomized, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of Stereotactic Body Radiotherapy (SBRT) with or without Pembrolizumab (MK-3475) in Participants with Medically Inoperable Stages I or IIA Non Small Cell Lung Cancer (NSCLC) (KEYNOTE-867)

Cancer Type: Thoracic

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CLINICAL TRIAL 20061

A Pilot Study of CPX-351 (Vyxeos) for Transplant Eligible, Higher Risk Patients with Myelodysplastic Syndrome

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19367

A Phase 1b Study of Adaptive Androgen Deprivation Therapy for Stage IV Castration Sensitive Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 20282

A Randomized Phase II/III Trial of De-Intensified Radiation Therapy for Patients with Early-Stage, P16 Positive, Non-Smoking Associated Oropharyngeal Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 19758

Open Label Phase 2 Study of Tisotumab Vedotin for Patients with Platinum-Resistant Ovarian Cancer with a Safety Run-in of a Dose-Dense Regimen

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20113

Phase 1/2 FIH Study of Regn5458 (Anti-BCMA X Anti-CD3 Bispecific Antibody) in Patients with Relapsed or Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20174

A Phase I, Open-Label, Dose Finding Study To Assess The Safety, Tolerability, Pharmacokinetics, And Preliminary Efficacy Of OBT076, A CD205-Directed Antibody-Drug Conjugate, In Recurrent And/Or Metastatic CD205 Positive Solid Tumors And In Women With CD205 Positive HER2-Negative Metastatic Breast Cancer

Cancer Type: Multiple

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CLINICAL TRIAL 19660

Treatment Free Remission After Combination Therapy with Ruxolitinib Plus Tyrosine Kinase Inhibitors in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20117

A Phase 1/2 Study of Regn5678 (Anti-psmaxcd28) with Cemiplimab (Anti-pd-1) in Patients with Metastatic Castration-Resistant Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 20144

A Phase 1, First-in-Human, Open-Label, Dose Escalation and Expansion Study of CUE-101 Monotherapy in Second Line and CUE-101 Combination Therapy with Pembrolizumab in First Line Patients with HPV16+ Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)

Cancer Type: Head & Neck

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CLINICAL TRIAL 19585

A Phase 2 Study to Assess the Efficacy, Safety, Pharmacokinetic and Pharmacodynamic Parameters of Umbralisib in Treatment Naïve Patients with Chronic Lymphocytic Leukemia (CLL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20187

Development of Intra-tumor Driver Mutation Prevalence as a Predictor of Efficacy of Targeted Agents

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20246

Elacestrant Monotherapy VS. Standard of Care for the Treatment of Patients with ER+/HER2- Advanced Breast Cancer Following CDK4/6 Inhibitor Therapy: A Phase 3 Randomized, Open-Label, Active-Controlled, Multicenter Trial (EMERALD)

Cancer Type: Breast

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CLINICAL TRIAL 20274

A Phase II/III Randomized Study of Maintenance Nivolumab versus Observation in Patients with Locally Advanced, Intermediate Risk HPV Positive OPCA

Cancer Type: Head & Neck

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CLINICAL TRIAL 20248

A Phase 1, Open-Label Study to Assess The Pharmacokinetics, Pharmacodynamics and Central Nervous System (CNS) Penetration of CC-90010 in Preoperative Subjects with Progressive or Recurrent who Grade II Diffuse Astrocytoma, Grade III Anaplastic Astrocytoma and Recurrent Glioblastoma Scheduled for Resection

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20131

Reduced-Intensity Fludarabine, Melphalan, and Total Body Irradiation Conditioning for Transplantation of HLA-Haploidentical Related Hematopoietic Cells (Haplo-HCT) For Patients With Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20179

Phase 1/2 Study of 9-ING-41, a Glycogen Synthase Kinase-3 Beta (GSK-3beta) Inhibitor, as a Single Agent and Combined with Chemotherapy, in Patients with Refractory Hematologic Malignancies or Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 20309

A Phase 3, Interventional, Randomized, Multicenter, Open-Label Study of DCC-2618 vs Sunitinib in Patients with Advanced Gastrointestinal Stromal Tumors after Treatment with Imatinib

Cancer Type: Sarcoma

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CLINICAL TRIAL 20110

GBM Agile: Global Adaptive Trial Master Protocol

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20251

A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR T cells in subjects with Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma (SPEARHEAD 1 Study)

Cancer Type: Immunotherapy

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CLINICAL TRIAL 20382

Interaction of Epigenetic Modulators and Immune Checkpoint Inhibitors in Gynecologic Cancers and associated Endometriosis

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19858

A Phase I/II Open-label, Multi-center Study of the Safety and Efficacy of IMCnyeso, an HLA- A*0201-Restricted, NY-ESO-1- and LAGE-1A-specific Soluble T Cell Receptor and Anti-CD3 Bispecific Molecule, as a Single Agent in HLA-A*0201 Positive Patients with Advanced NY-ESO-1 and/or LAGE-1A Positive Cancer

Cancer Type: Sarcoma

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CLINICAL TRIAL 20252

A Phase 3, Multicenter, Randomized, Open-label, Active-Controlled Trial Of Ds-8201a, An Anti-Her2-Antibody Drug Conjugate (Adc), Versus Treatment Of Physicians Choice For Her2-low, Unresectable And/Or Metastatic Breast Cancer Subjects

Cancer Type: Breast

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CLINICAL TRIAL 20287

A Phase 1b/2 Study of IMGN632 as Monotherapy or Combination with Venetoclax and/or Azacitidine for Patients with CD123-Positive Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20260

A Phase 2 Efficacy and Safety Trial of ADU-S100 and Pembrolizumab in Adults with Head and Neck Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 19765

Phase Ib Study of Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases

Cancer Type: Breast

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CLINICAL TRIAL 18989

A Phase 1b/2 Study of PV-10 Intralesional Injection in Combination with Systemic Immune Checkpoint Inhibition for Treatment of Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20482

Simultaneous Assessment of Biomarkers in the TME and Circulation of Metastatic Melanoma Patients Treated with Ipilimumab and Ipilimumab with Interferon-alfa in E3611

Cancer Type: Cutaneous

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CLINICAL TRIAL 19634

Study of Resistance Mechanisms to Checkpoint Blockade

Cancer Type: Cutaneous

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CLINICAL TRIAL 19950

Linking the Skin and Gut Microbiome to Immunosuppression in Skin Cancer

Cancer Type: Cutaneous

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CLINICAL TRIAL 18826

A Phase 1 Study of ALKS 4230 Administered Intravenously as Monotherapy and in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors

Cancer Type: Genitourinary

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CLINICAL TRIAL 19163

Combination Immunotherapy with Ipilimumab and Nivolumab plus a Dendritic Cell based p53 Vaccine (Ad.p53-DC) in patients with relapsed Small Cell Lung Cancer (SCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 18613

Phase II Study of nab-Paclitaxel in Combination with Gemcitabine for Treatment of Recurrent/Refractory Sarcoma in Teenagers and Young Adults

Cancer Type: Sarcoma

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CLINICAL TRIAL 18862

A phase 1, open-label, dose-escalation study to evaluate the safety and tolerability of SGN-LIV1A in patients with metastatic breast cancer

Cancer Type: Breast

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CLINICAL TRIAL 20162

Phase 1 Trial of Intralesional Immunotherapy with IFx-Hu2.0 Vaccine in Patients with Advanced Merkel Cell Carcinoma or Cutaneous Squamous Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 18661

Phase I Trial of Hypofractionated Stereotactic Irradiation (HFSRT) Combined with Nivolumab, Ipilimumab and Bevacizumab in Patients with Recurrent High Grade Gliomas

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20247

A Phase 2b Trial of the MEK 1/2 Inhibitor (MEKi) PD-0325901 in Adult and Pediatric Patients with Neurofibromatosis Type 1 (NF1)-Associated Inoperable Plexiform Neurofibromas (PNs) that are Causing Significant Morbidity

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19305

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19466

Exploring Adherence to CDK4/6 Inhibitors among Metastatic Breast Cancer Patients

Cancer Type: Breast

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CLINICAL TRIAL 20175

A Two-arm, Randomized, Non-comparative, Phase 2 Trial of AGEN2034 (anti-PD-1) as a Monotherapy or Combination Therapy with AGEN1884 (anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer (Second Line) - RaPiDS

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19695

S1602: A Phase III Randomized Trial to Evaluate the Influence of BCG Strain Differences and T Cell Priming with Intradermal BCG Before Intravesical Therapy for BCG‐Naïve High‐Grade Non‐Muscle Invasive Bladder Cancer.

Cancer Type: Genitourinary

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CLINICAL TRIAL 19635

A Phase 1b/2 Study Evaluating the Safety and Efficacy of Intravenous LB-100 in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) who had Disease Progression or are Intolerant to Prior Therapy

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20300

A Phase 3, Randomized, Double-blind Study of Pembrolizumab (MK-3475) Plus Docetaxel Plus Prednisone versus Placebo Plus Docetaxel Plus Prednisone in Participants with Chemotherapy-naive Metastatic Castration-Resistant Prostate Cancer (mCRPC) who have Progressed on a Next Generation Hormonal Agent (NHA) (KEYNOTE- 921)

Cancer Type: Genitourinary

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CLINICAL TRIAL 20114

A Single Arm Phase II Study of Cemiplimab-rwlc in Immunocompromised Patients with Unresectable Locally Recurrent and/or Metastatic Cutaneous Squamous Cell Carcinoma (CSCC)

Cancer Type: Head & Neck

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CLINICAL TRIAL 19684

A Phase I/Ib, Open-Label, Multi-Center Study of NZV930 as a Single Agent and in Combination with PDR001 and/or NIR178 in Patients with Advanced Malignancies

Cancer Type: Thoracic

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CLINICAL TRIAL 19862

A Phase 1/1b Safety Study of PRGN-3006 Adoptive Cellular Therapy in Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndrome

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19580

A Phase 1/2 Dose Escalation and Dose Expansion Study of BA3011 in Patients with Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 20356

Patient and Caregiver Dyads in Pancreatic Cancer: Assessment of Patient Distress and its Association with Caregiver Well-Being

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 18610

A Phase I-II Study of Triciribine Phosphate Monohydrate (PTX-200) Plus Cytarabine in Refractory or Relapsed Acute Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19428

A Phase 1/2, Multicenter, Dose-Escalation and Expansion Study of Combination Therapy with Venetoclax, Daratumumab and Dexamethasone (With and Without Bortezomib) in Subjects with Relapsed or Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20257

Barriers to Screening Breast MRI Utilization Among Patients at Elevated Risk (B-SUPER)

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19569

A Phase 1/2 Study of Combination Immunotherapy and mRNA Vaccine in Subjects with Non-small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 17690

A Phase I Trial of Single Agent Trametinib (GSK1120212) in Advanced Cancer Patients with Hepatic Dysfunction

Cancer Type: Multiple

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CLINICAL TRIAL 19581

Phase I study of Regorafenib and Nivolumab in Mismatch Repair (MMR) Proficient Advanced Refractory Colorectal Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19708

Biological Outcomes of Pramlintide in Resectable Cutaneous Squamous Cell Carcinoma: A Pilot Study

Cancer Type: Cutaneous

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CLINICAL TRIAL 19731

Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator Intervention for Neuro-Oncology Couples

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20342

Development of a Multi-Behavioral Intervention to Reduce Cancer Health Disparities: Promotion of Hepatitis C Virus Screening and Colorectal Cancer Screening Uptake Among Diverse Baby Boomers

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 20347

A phase 2 basket trial of glutaminase inhibitor (BeGIN) CB-839 HCl in patients with NF1 Aberrations, NF1 mutant malignant peripheral nerve sheath tumors (MPNST), KEAP1/NRF2 and LKB1 Aberrant tumors

Cancer Type: Sarcoma

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CLINICAL TRIAL 19481

Phase I, Open Label Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Expansion, Persistence and Clinical Activity of UCART123 (Allogeneic Engineered T Cells Expressing anti-CD123 Chimeric Antigen Receptor), Administered in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20105

Using Radiogenomics to Noninvasively Predict the Malignant Potential of Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas and Uncover Hidden Biology

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20102

A Phase 2 Study of the Hepcidin Mimetic PTG-300 in Patients with Phlebotomy-Requiring Polycythemia Vera.

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20152

A Phase III Double-blind Randomised Study Assessing the Efficacy and Safety of Capivasertib + Paclitaxel Versus Placebo + Paclitaxel as First-line Treatment for Patients with Histologically Confirmed, Locally Advanced Inoperable) or Metastatic Triple-Negative Breast Cancer (TNBC)

Cancer Type: Breast

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CLINICAL TRIAL 19137

A Randomized Phase II Trial of Abiraterone, Olaparib, or Abiraterone + Olaparib in Patients with Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects

Cancer Type: Genitourinary

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CLINICAL TRIAL 20132

Phase 1/2 Dose-Escalation and Expansion Study of FLX475 Alone and in Combination with Pembrolizumab in Advanced Cancer

Cancer Type: Multiple

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CLINICAL TRIAL 20278

A Single Arm, Open Label, Phase II Study of Ruxolitinib in Sclerotic Chronic Graft-Versus-Host Disease after Failure of Systemic Glucocorticoids

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20403

Molecular Biology of Concomitant Mycosis Fungoides/Sezary Syndrome (MF/SS) Cells and Clonal Large Granular Lymphocytic (LGL) Proliferations in Peripheral Blood

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20315

Phase II Study of XL184 (cabozantinib) in combination with Nivolumab and Ipilimumab (CaboNivoIpi) in Patients with Radioiodine-refractory Differentiated Thyroid Cancer whose Cancer Progressed after One Prior VEGFR-Targeted Therapy

Cancer Type: Head & Neck

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CLINICAL TRIAL 19356

A Phase 1b Trial of the IRX-2 Regimen and Durvalumab (MEDI4736), in Patients with Incurable Head and Neck Squamous Cell Carcinoma

Cancer Type: Head & Neck

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CLINICAL TRIAL 19873

A Phase II Open Label Single Arm Study of Adjuvant Nivolumab following Chemo-Radiation in localized Muscle-Invasive Bladder Cancer (NEXT)

Cancer Type: Genitourinary

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CLINICAL TRIAL 18094

A Phase 2 Study of Transarterial Chemoperfusion Treatment with Cisplatin, Methotrexate and Gemcitabine in Patients with Unresectable Pleural Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL 20314

A Phase 2 Study of Neoadjuvant Cemiplimab for Stage II to IV (M0) Cutaneous Squamous Cell Carcinoma (CSCC)

Cancer Type: Cutaneous

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CLINICAL TRIAL 20372

Axicabtagene Ciloleucel:Neurocognitive and Patient-Reported Outcomes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 90001

A Phase 2, Multicenter, Single-Arm Study of Retreatment with Brentuximab Vedotin in Subjects with Relapsed or Refractory Classic Hodgkin lymphoma (cHL) or CD30-Expressing Peripheral T Cell Lymphoma (PTCL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 50337

Optimization of High-Grade Glioma Tissue Dissociation for the Maintenance of Cell Viability

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19971

Molecular Markers of UV Exposure and Cancer Risk in Skin

Cancer Type: Cutaneous

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CLINICAL TRIAL 20256

CemiplimAb Survivorship Epidemiology (CASE) Study

Cancer Type: Cutaneous

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CLINICAL TRIAL 19985

A Phase 2, Multicenter, Open-label, Safety and Efficacy Study of XERMELO® (Telotristat Ethyl) plus First-line Chemotherapy in Patients with Locally Advanced, Unresectable, Recurrent or Metastatic Biliary Tract Cancer (BTC)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19746

A Multicenter, Open-Label, Dose Escalation Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of the DNA-PK Inhibitor M3814 in Combination with Avelumab with and without Palliative Radiotherapy in Participants with Selected Advanced Solid Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 20397

A Phase 2, Single-Arm, Open-Label Study of Itacitinib, for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy

Cancer Type: Immunotherapy

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CLINICAL TRIAL 19870

A Phase 1, Multi-center, Open-label Study of IMGN632 Administered Intravenously in Patients with Relapsed/Refractory CD123-positive Acute Myeloid Leukemia and Other CD123-positive Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20415

A Phase III, Open-Label, Multicenter, Randomized Study Evaluating The Saftey And Efficacy Of Polatuzumab Vedotin In Combination With RituximabI Plus Gemcitabine Plus Oxaliplatin (R-Gemox) Versus R-Gemox Alone In Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19482

A Single-Arm, Open-Label Phase 2 Pilot Study of Vyxeos (CPX-351) in Adults with Relapsed or Refractory Acute Lymphoblastic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20563

Methylation Signatures in Cell-free DNA for Tumor Classification and Early Detection

Cancer Type: Multiple

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CLINICAL TRIAL 90002

Phase I Safety Study of Descartes-11 in Patients with Relapsed/Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20329

The PISCES study: A Multicenter Phase 2, Open-Label Study of Intratumoral Tavokinogene Telseplasmid (tavo, pIL-12) plus Electroporation in Combination with Intravenous Pembrolizumab in Patients with Stage III/IV Melanoma who are Progressing on either Pembrolizumab or Nivolumab Treatment

Cancer Type: Cutaneous

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CLINICAL TRIAL 20413

Phase III Study Of Daratumumab/Rhuph20 (Nsc- 810307) + Lenalidomide Or Lenalidomide As Post-Autologous Stem Cell Transplant Maintenance Therapy In Patients With Multiple Myeloma (MM) Using Minimal Residual Disease To Direct Therapy Duration (DRAMMATIC STUDY)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20364

A Phase 1/2 Study of REGN5093 in Patients with Met-Altered Advanced Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 20622

REACT COVID-19: Real world Evidence for Anti-Cytokine Therapy in COVID-19, an International, Multi-center, Observational Study

Cancer Type: Multiple

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CLINICAL TRIAL 20258

A Phase 1 Dose Escalation With Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMV564 in Subjects with Advanced Solid Tumors

Cancer Type: Immunotherapy

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CLINICAL TRIAL 20585

Development of a Quality of Life Decision-Making Model for Older Patients with Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20266

A Phase 1a/1b Dose Escalation and Expansion Trial of TTI-621, a Novel Biologic Targeting CD47, in Subjects with Relapsed or Refractory Hematologic Malignancies and Selected Solid Tumors

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20474

A Phase 1b, First-in-Human, Dose Escalation and Expansion Study of XMT-1536 In Patients with Solid Tumors Likely to Express NaPi2b

Cancer Type: Thoracic

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CLINICAL TRIAL 20101

Phase I Study of AVID200 in Patients with Myelofibrosis (Myeloproliferative Neoplasms Research Consortium [MPN-RC] 118)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19337

A Pilot Study Utilizing a HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+ Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 20507

An Open-Label, Randomized, Controlled Phase 3 Study of Enfortumab Vedotin in Combination with Pembrolizumab with or without Chemotherapy, versus Chemotherapy Alone in Previously Untreated Locally Advanced or Metastatic Urothelial Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 20576

A Phase 2 Study of MLN4924 (Pevonedistat) in Combination with Carboplatin and Paclitaxel in Advanced NSCLC Previously Treated with Immunotherapy

Cancer Type: Thoracic

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CLINICAL TRIAL 20363

A Phase 2a, Open-Label, Multi-Center Study to Assess the Efficacy and Safety of Marrow Infiltrating Lymphocytes NonSmall Cell Lung Cancer (MILs - SCLC) Alone or in Combination with Nivolumab in Subjects with Locally Advanced and Unresectable or Metastatic NSCLC Previously Treated with Anti-PD-1

Cancer Type: Immunotherapy

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CLINICAL TRIAL 19342

A Phase I Trial of Pembrolizumab and Vorinostat Combined with Temozolomide and Radiation Therapy for Newly Diagnosed Glioblastoma

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20159

A Phase 1 Study of ZW49 in Patients with Locally Advanced (Unresectable) or Metastatic HER2-Expressing Cancers

Cancer Type: Breast

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CLINICAL TRIAL 20543

Long-term Follow-Up Study of Patients Who Have Previously Been Exposed to UCART19/ALLO-501 (Allogeneic Engineered T-Cells Expressing a Lentiviral-Based Anti-CD19 Chimeric Antigen Receptor)

Cancer Type: Immunotherapy

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CLINICAL TRIAL 20485

A Motion Exergaming Approach to Promote Self-Managing Fatigue and Pain after Head and Neck Cancer Treatment

Cancer Type: Head & Neck

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CLINICAL TRIAL 20636

Proteogenomics of Metastatic Heterogeneity and Therapeutic Resistance in Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 18815

A Phase 2 Study of Tipifarnib in Subjects with Chronic Myelomonocytic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20377

A Phase 2 Multicohort Study of Nivolumab in Combination with Docetaxel and Androgen Deprivation Therapy in Metastatic Hormone Sensitive Prostate Cancer Patients with DNA Damage Repair Defects or Inflamed Tumors

Cancer Type: Genitourinary

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CLINICAL TRIAL 20578

A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmocodynamics of ALLO-501A, an Anti-CD19 Allogeneic Car T Cell Therapy in Subjects with Relapsed/Refractory Large B-Cell Lymphoma (LBCL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20388

Phase 2 Trial of Brigatinib After Treatment with Next-Generation ALK Inhibitors in Refractory ALK Rearranged NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 19594

A Multicenter, Non-Randomized, Open-label Dose Escalation Phase Ib Study of Regorafenib in Combination with Pembrolizumab in Patients with Advanced Hepatocellular Carcinoma (HCC) with No Prior Systemic Therapy

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20419

Phase II Study of Short Course FOLFOX Chemotherapy with Either Nivolumab or Nivolumab + Radiation in the First Line Treatment of Metastatic or Unresectable Gastroesophageal Cancers (BMS Protocol CA209-76L)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20336

A Phase II Trial of Ribociclib (LEE011) plus Letrozole in Women with Recurrent Low-Grade Serous Carcinoma of the Ovary, Fallopian Tube or Peritoneum

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19475

Phase 1 Study of Trametinib + Ceritinib in Patients with Unresectable Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20299

A Phase 1 Study of Pre-Operative Cemiplimab (REGN2810) Administered Intralesionally, for Patients with Recurrent Cutaneous Squamous Cell Carcinoma (CSCC)

Cancer Type: Cutaneous

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CLINICAL TRIAL 20123

A Dose-Optimization, Exploratory Phase Ib/II Study to Assess Safety and Efficacy of the Second Mitochondrial-derived Activator of Caspases (SMAC) Mimetic Debio 1143, When Given in Combination with the Anti-PD-1 Antibody Nivolumab in Patients with Specific Solid Tumors who have Progressed During or Immediately after anti-PD-1/PD-L1 Treatment

Cancer Type: Multiple

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CLINICAL TRIAL 20271

A Global Randomized Multicenter Phase 3 Trial to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects with High-Risk, Transplant-Eligible Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphomas (TRANSFORM)

Cancer Type: Immunotherapy

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CLINICAL TRIAL 20529

A Randomised, Multicentre, Double-blind, Placebo-controlled, Phase III Study of First-line Carboplatin and Paclitaxel in Combination with Durvalumab, Followed by Maintenance Durvalumab with or without Olaparib in Patients with Newly Diagnosed Advanced or Recurrent Endometrial Cancer (DUO-E)

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20298

A Phase I/II, Open-Label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-Tumor Activity of YH25448 in Patients with EGFR Mutation Positive Advanced Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 19658

A Phase 1, Open-Label, Dose-Escalation with Expansion Study of SX-682 in Subjects with Myelodysplastic Syndrome Who Had Disease Progression or are Intolerant to Prior Therapy

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19429

A Phase 2 Single-Arm, Open-Label Study Evaluating Tolerability and Efficacy of Navitoclax in Combination with Ruxolitinib in Subjects with Myelofibrosis

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20349

A Phase 2 Study of TAS-120 in Metastatic Breast Cancers Harboring Fibroblast Growth Factor Receptor (FGFR) Amplifications

Cancer Type: Breast

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CLINICAL TRIAL 20728

Expanded Access to Convalescent Plasma for the Treatment of Patients with COVID-19

Cancer Type: Multiple

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CLINICAL TRIAL 20310

Family Building Decisions Among Adolescent Young Adults (AYAs) Patients with Inherited Cancer Risk and Their Partner Dyads

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 20373

TH-138: Phase II Randomized Trial of Carboplatin + Pemetrexed + Bevacizumab, With or Without Atezolizumab in Stage IV Non-Squamous NSCLC Patients who Harbor a Sensitizing EGFR Mutation or Have Never Smoked.

Cancer Type: Thoracic

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CLINICAL TRIAL 20534

A Phase 1b Dose-Escalation Study of Cabozantinib (XL184) Administered Alone or in Combination with Atezolizumab to Subjects with Locally Advanced or Metastatic Solid Tumors

Cancer Type: Genitourinary

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CLINICAL TRIAL 20475

First-in-Human, Open-Label, Dose-Escalation Trial with Expansion Cohorts to Evaluate Safety of Axl-Specific Antibody-Drug Conjugate (Enapotamab Vedotin, HuMax®-AXL-ADC) in Patients with Solid Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 20304

A Phase 1/2, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of AMG 510 Monotherapy in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation and AMG 510 Combination Therapy in Subjects With Advanced NSCLC With KRAS p.G12C Mutation (Codebreak 100)

Cancer Type: Thoracic

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CLINICAL TRIAL 20082

Pilot Trial of Enasidenib Maintenance Post Allogeneic Hematopoietic Cell Transplantation in Patients with IDH2 Mutation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20375

Phase I Study of APR-246 in Combination with Venetoclax and Azacitidine in TP53-Mutant Myeloid Malignancies

Cancer Type: Malignant Hematology

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