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Clinical Trial 16028

Cancer Type:
Interventions:

Study Type: Other
Phase of Study: Pilot
Investigators:

  • Erin Siegel

Call 813-745-6100
or 1-800-679-0775
Overview

Study Title

Transdisciplinary Research in Colorectal Cancer: The ColoCare Study

Summary

This is a research study of colorectal cancer. Our long-term goals are to learn how to improve treatment success in future patients and what future patients can do to improve their health after diagnosis. For example, testing may be done to find new ways to tailor therapy, or to evaluate a patient's health status after a colorectal cancer diagnosis.

Objective

This study will establish a cohort of 250 colorectal cancer patients with a comprehensive assessment of quality of life, health behaviors and medical history, study collected blood samples at baseline (surgery) and during follow-up (6 and 12 months), and TCC generated gene expression analysis. The central hypothesis of this research is that colorectal cancer patients with elevated levels of IGF and insulin/glucose biomarkers will demonstrate distinct gene expression alterations in IGF-related signaling pathways and will have both altered systemic inflammation and worse quality of life.

Inclusion Criteria

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  • 18 years of age or older
  • newly-diagnosed Stage I-IV colorectal cancer
  • no previous chemotherapy, radiation or surgical treatment