Open Clinical Trials:
CLINICAL TRIAL 19456
Phase III Randomized Study of Crenolanib versus Midostaurin Administered Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed Subjects with FLT3 Mutated Acute Myeloid Leukemia
Disease Site: Acute Leukemia (ALL, AML), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 19481
Phase I, Open Label Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Expansion, Persistence and Clinical Activity of UCART123 (Allogeneic Engineered T Cells Expressing anti-CD123 Chimeric Antigen Receptor), Administered in Patients with Relapsed/Refractory Acute Myeloid Leukemia
Disease Site: Acute Leukemia (ALL, AML), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 19742
Phase 1/1b Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemia
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 19862
A Phase 1/1b Safety Study of PRGN-3006 Adoptive Cellular Therapy in Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndrome
Disease Site: Acute Leukemia (ALL, AML), Myelodysplastic syndrome (MDS), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 19870
A Phase 1, Multi-center, Open-label Study of IMGN632 Administered Intravenously in Patients with Relapsed/Refractory CD123-positive Acute Myeloid Leukemia and Other CD123-positive Hematologic Malignancies
Disease Site: Acute Leukemia (ALL, AML), Myeloid and Monocytic Leukemia, Other hematologic
View Trial DetailsCLINICAL TRIAL 20042
CD8 Depleted, Non-Engrafting, HLA Mismatched Unrelated Donor Lymphocyte Infusion in Patients with MDS and Secondary AML
Disease Site: Acute Leukemia (ALL, AML), Myelodysplastic syndrome (MDS), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20287
A Phase 1b/2 Study of IMGN632 as Monotherapy or Combination with Venetoclax and/or Azacitidine for Patients with CD123-Positive Acute Myeloid Leukemia
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20305
Phase 1/1b Trial of Donor gamma delta T-cell Infusion for Treatment of Patients with Acute Myeloid Leukemia at High Risk of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
Disease Site: Leukemia, other, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20415
A Phase III, Open-Label, Multicenter, Randomized Study Evaluating The Safety And Efficacy Of Polatuzumab Vedotin In Combination With RituximabI Plus Gemcitabine Plus Oxaliplatin (R-Gemox) Versus R-Gemox Alone In Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20484
A Phase 2 Study of Donor-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-401) Administered to Patients with Acute Myeloid Leukemia (AML) following Hematopoietic Stem Cell Transplantation
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20552
A Phase 1b/2 Study Evaluating the Safety and Efficacy of Canakinumab with Darbepoetin alfa in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) who have Failed Erythropoietin Stimulating Agents (ESA)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20733
A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzomab Ozogamicin (a conjugated anti-CD22 monoclonal antibody) to Frontline Therapy in Young Adults (ages 18-39 years) with Newly Diagnosed Precusor B-cell ALL
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20749
A Phase 1, Open Label Dose Escalation Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered CA-4948 in Patients with Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Disease Site: Leukemia, other, Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20752
A Phase 1 Study of Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated Acute Myeloid Leukemia
Disease Site: Leukemia, other, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20877
A Phase Ib /Randomized Phase III Trial of Patients with Advanced Hematologic Malignancies Undergoing Allogeneic Hematopoietic Cell Transplantation with Either Orca-T, a T-cell-Depleted Graft with Additional Infusion of Conventional T cells and Regulatory T cells, or Standard-of-Care Allogeneic Graft
Disease Site: Leukemia, other, Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20923
A Phase I/II Trial of Maintenance Fedratinib to Prevent Post-Transplant Relapse in Myeloproliferative Neoplasms
Disease Site: Leukemia, other, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20963
A Phase 2 Study of Fedratinib in Myelodysplastic /Myeloproliferative Neoplasms (MDS/MPNs) and Chronic Neutrophilic Leukemia (CNL)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21057
A Randomized, Double-Blind, Phase 3 Study Evaluating the Safety and Efficacy of Venetoclax in Combination with Azacitidine in Patients Newly Diagnosed with Higher-Risk Myelodysplastic Syndrome (Higher-Risk MDS)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21090
A Study to Evaluate Imetelstat (GRN163L) in Transfusion-Dependent Subjects with IPSS Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) that is Relapsed/Refractory to Erythropoiesis-Stimulating Agent (ESA) Treatment
Disease Site: Myelodysplastic syndrome (MDS), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21142
A Phase 1b, Multicenter, Open-label Platform Study of Select Drug Combinations in Adult Patients with Lower Risk (Very Low, Low, or Intermediate Risk) Myelodysplastic Syndrome (CMBG453E12101)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21167
A Phase 1/2 Open-label Study Investigating the Safety, Tolerability and Efficacy of ASP7517 in Subjects with Relapsed/Refractory Acute Myeloid Leukemia (AML) and Relapsed/Refractory Higher Risk Myelodysplastic Syndrome (MDS)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21186
ACCESS: A Multi-Center, Phase II Trial of HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide for Patients with Hematologic Malignancies
Disease Site: Leukemia, other, Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21248
A Phase 3, Randomized, Open-Label Study Evaluating the Safety and Efficacy of Magrolimab in Combination with Azacitidine versus Physician s Choice of Venetoclax in Combination with Azacitidine or Intensive Chemotherapy in Previously Untreated Patients with TP53 Mutant Acute Myeloid Leukemia
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21405
Phase 2, Single Arm Study of Luspatercept for the Treatment of Anemia in lower Risk Myelodysplastic Syndromes (MDS) or Non-proliferative Myelodysplastic Syndromes/Myeloproliferative Neoplasms (MDS/MPN)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21450
A Phase 1/1b Dose Escalation and Expansion of CPX-351 in Combination with Gemtuzumab Ozogamicin in Newly Diagnosed Acute Myeloid Leukemia
Disease Site: Myeloid and Monocytic Leukemia, Acute Leukemia (ALL, AML)
View Trial DetailsCLINICAL TRIAL 21756
A Phase 3 Study of the Hepcidin Mimetic Rusfertide (PTG-300) in Patients with Polycythemia Vera
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21761
A Phase 1 First-in-Human Dose-escalation and Dose-expansion Study of BMF-219, an Oral Irreversible Menin Inhibitor, in Adult Patients with Acute Leukemia Including Those with an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Disease Site: Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21778
An Open-Label Phase 1A/1B Dose Escalation and Expansion Cohort Study of SL-172154 (SIRPα-Fc-CD40L) in Combination With Azacitidine or With Azacitidine and Venetoclax for the Treatment of Subjects With Higher-Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 18926
The National Myelodysplastic Syndromes (MDS) Study
Disease Site: Leukemia, other, Lymphoid Leukemia, Multiple Myeloma, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20585
Development of a Quality of Life Decision-Making Model for Older Patients with Acute Myeloid Leukemia
Disease Site: Acute Leukemia (ALL, AML), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21752
Chimeric Antigen Receptor T-Cell Therapy: Neurocognitive Effects and Patient-Reported Outcomes
Disease Site: Hodgkin's Lymphoma, Leukemia, other, Lymphoid Leukemia, Multiple Myeloma, Myeloid and Monocytic Leukemia, Non-Hodgkin's Lymphoma, Other Hematopoietic
View Trial DetailsCLINICAL TRIAL 21561
Assessment of Chimerism and Relapse Post-Bone Marrow / Hematopoietic Cell Transplant (HCT) using ALLOHEME Test (ACROBAT)
Disease Site: Leukemia, other, Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial Details