Margaret Booth-Jones, PhD

My research has focused on cognitive changes associated with cancer and cancer treatment and the impact on quality of life and emotional well-being.

Associations

• Supportive Care Medicine
• Health Outcomes & Behavior Program

Education & Training

Graduate:

• University of Florida, MS - Clinical and Health Psychology

Fellowship:

• University of Florida - Clinical and Health Psychology

Residency:

• University of Chicago Medical Center - Psychiatry

Medical School:

• University of Florida - PhD

Dr. Booth-Jones' research focuses on cognitive changes in cancer patients and their subsequent impact on psychosocial function and emotional well-being. She also is interested in the impact of these cognitive changes on caregivers and the family system. The goal of this work is to use neuropsychological and psychological knowledge and methods to identify and treat cancer-related cognitive morbidity and maximize quality of life during and after cancer care. Over the past few years, Dr. Booth-Jones has conducted or participated in several studies investigating the cognitive changes observed during cancer treatment and the long-term consequences of cancer treatment on cognitive function and on returning to premorbid roles. Dr. Booth-Jones has focused much of her research on patients undergoing bone marrow transplantation and their functioning in the first year following transplant. Her objective is to determine the trajectory of recovery and identify psychosocial and medical variables that have an impact on recovery of premorbid abilities and return to pretransplant psychological state. Dr. Booth-Jones' other research interests include the practical aspects of neuropsychological testing in a cancer setting, the use of computerized testing batteries in the senior adult population, and the use of computerized driving evaluations to assist with determining driving ability of patients with brain tumors or cognitive changes associated with opiate use. Studies in these areas would have both clinical and research applications.

• Hyland KA, Eisel SL, Hoogland AI, Root JC, Bowles K, James B, Nelson AM, Booth-Jones M, Jacobsen PB, Ahles TA, Jim HSL, Gonzalez BD. Cognition in patients treated with targeted therapy for chronic myeloid leukemia: a controlled comparison. Leuk Lymphoma. 2023 Feb.64(2):415-423. Pubmedid: 36476293. Pmcid: PMC10305842.
• Hoogland AI, Barata A, Logue J, Kommalapati A, Hyland KA, Nelson AM, Eisel SL, Small BJ, James BW, Christy SM, Bulls HW, Booth-Jones M, Jayani RV, Jain MD, Mokhtari S, Chavez JC, Lazaryan A, Shah BD, Locke FL, Jim HSL. Change in Neurocognitive Performance Among Patients with Non-Hodgkin Lymphoma in the First Year after Chimeric Antigen Receptor T Cell Therapy. Transplant Cell Ther. 2022 Jun.28(6):305.e1-305.e9. Pubmedid: 35378330. Pmcid: PMC9197947.
• Barata A, Hoogland AI, Kommalapati A, Logue J, Welniak T, Hyland KA, Eisel SL, Small BJ, Jayani RV, Booth-Jones M, Oswald LB, Gonzalez BD, Kirtane KS, Jain MD, Mokhtari S, Chavez JC, Lazaryan A, Shah BD, Locke FL, Jim HSL. Change in Patients' Perceived Cognition Following Chimeric Antigen Receptor T-Cell Therapy for Lymphoma. Transplant Cell Ther. 2022 Jul.28(7):401.e1-401.e7. Pubmedid: 35580732. Pmcid: PMC9339228.
• Hoogland AI, Jayani RV, Collier A, Irizarry-Arroyo N, Rodriguez Y, Jain MD, Booth-Jones M, Hyland KA, James BW, Barata A, Bachmeier CA, Chavez JC, Khimani F, Krivenko GS, Lazaryan A, Liu HD, Nishihori T, Pinilla-Ibarz J, Shah BD, Abidi M, Locke FL, Jim HSL. Acute patient-reported outcomes in B-cell malignancies treated with axicabtagene ciloleucel. Cancer Med. 2021 Mar.10(6):1936-1943. Pubmedid: 33641257. Pmcid: PMC7957158.
• Hernandez J, Lubrano di Ciccone B, Thirlwell S, Booth-Jones M, Aslam S, Greene J. COVID-19 pandemic causing medical and public health ethical dilemmas: A case report and review of literature. Qual Res Med Healthc. 2021 Mar.5(1).
• Barata A, Hoogland AI, Hyland KA, Otto AK, Kommalapati A, Jayani RV, Irizarry-Arroyo N, Collier A, Rodriguez Y, Welniak TL, Booth-Jones M, Logue J, Small BJ, Jain MD, Reblin M, Locke FL, Jim HSL. Quality of life in caregivers of patients receiving chimeric antigen receptor T-cell therapy. Psychooncology. 2021 Aug.30(8):1294-1301. Pubmedid: 33739548. Pmcid: PMC9828891.
• Barata A, Gonzalez BD, Zhou JM, Kim J, Hoogland AI, El-Jawahri A, Booth-Jones M, Jim HSL. Associations among depression, antidepressants, survival and quality of life in hematopoietic cell transplant recipients. Bone Marrow Transplant. 2020 Sep.55(9):1868-1871. Pubmedid: 32398786. Pmcid: PMC7968382.
• Hoogland AI, Nelson AM, Gonzalez BD, Small BJ, Breen EC, Sutton SK, Syrjala KL, Bower JE, Pidala J, Booth-Jones M, Jacobsen PB, Jim HSL. Worsening cognitive performance is associated with increases in systemic inflammation following hematopoietic cell transplantation. Brain Behav Immun. 2019 Aug.80:308-314. Pubmedid: 30953767. Pmcid: PMC6660393.
• Hoogland AI, Nelson AM, Small BJ, Hyland KA, Gonzalez BD, Booth-Jones M, Anasetti C, Jacobsen PB, Jim HSL. The Role of Age in Neurocognitive Functioning among Adult Allogeneic Hematopoietic Cell Transplant Recipients. Biol Blood Marrow Tr. 2017 Nov.23(11):1974-1979. Pubmedid: 28797784. Pmcid: PMC5682195.
• Gonzalez BD, Jim HS, Booth-Jones M, Small BJ, Sutton SK, Lin HY, Park JY, Spiess PE, Fishman MN, Jacobsen PB. Course and Predictors of Cognitive Function in Patients With Prostate Cancer Receiving Androgen-Deprivation Therapy: A Controlled Comparison. J Clin Oncol. 2015 Jun.33(18):2021-2027. Pubmedid: 25964245. Pmcid: PMC4461804.
• Brem S, Meyers CA, Palmer G, Booth-Jones M, Jain S, Ewend MG. Preservation of neurocognitive function and local control of 1 to 3 brain metastases treated with surgery and carmustine wafers. Cancer. 2013 Nov.119(21):3830-3838. Pubmedid: 24037801. Pmcid: PMC4209121.
• Jim HS, Small B, Hartman S, Franzen J, Millay S, Phillips K, Jacobsen PB, Booth-Jones M, Pidala J. Clinical predictors of cognitive function in adults treated with hematopoietic cell transplantation. Cancer. 2012 Jul.118(13):3407-3416. Pubmedid: 22139882. Pmcid: PMC3297700.
• Jim HS, Boyd TD, Booth-Jones M, Pidala J, Potter H. Granulocyte Macrophage Colony Stimulating Factor Treatment is Associated with Improved Cognition in Cancer Patients. Brain Disord Ther. 2012.1(1). Pubmedid: 22905341. Pmcid: PMC3422132.
• Wells KJ, Booth-Jones M, Jacobsen PB. Do coping and social support predict depression and anxiety in patients undergoing hematopoietic stem cell transplantation?. J Psychosoc Oncol. 2009.27(3):297-315. Pubmedid: 19544178. Pmcid: PMC3866098.
• Gross-King M, Booth-Jones M, Couluris M. Neurocognitive impairment in children treated for cancer: how do we measure cognitive outcomes?. J Pediatr Oncol Nurs. 2008 Sep.25(4):227-232. Pubmedid: 18559886.
• Jacobs S, Small B, Booth-Jones M, Jacobsen P, Fields K. Changes in cognitive functioning in the year after hematopoietic stem cell transplantation. Cancer. 2007 Oct.110(7):1560-1567. Pubmedid: 17685391.
• Jacobs S, Jacobsen P, Booth-Jones M, Wagner L, Anasetti C. Evaluation of the functional assessment of cancer therapy cognitive scale with hematopoietic stem cell transplant patients. J Pain Symptom Manag. 2007 Jan.33(1):13-23. Pubmedid: 17196903.
• Ransom S, Jacobsen P, Booth-Jones M. Validation of the Distress Thermometer with bone marrow transplant patients. Psychooncology. 2006 Jul.15(7):604-612. Pubmedid: 16208733.
• Fox S, Mitchell S, Booth-Jones M. Cognitive impairment in patients with brain tumors: assessment and intervention in the clinic setting. Clin J Oncol Nurs. 2006 Apr.10(2):169-176. Pubmedid: 16708701.
• Booth-Jones M, Jacobsen P, Ransom S, Soety E. Characteristics and correlates of cognitive functioning following bone marrow transplantation. Bone Marrow Transplant. 2005 Oct.36(8):695-702. Pubmedid: 16086044.
• Widows M, Jacobsen P, Booth-Jones M, Fields K. Predictors of posttraumatic growth following bone marrow transplantation for cancer. Health Psychol. 2005 May.24(3):266-273. Pubmedid: 15898862.
• Extermann M, Chen H, Booth-Jones M, Meyer J, Balducci L, Jacobsen P. Pilot testing of the computerized cognitive test Microcog in chemotherapy-treated older cancer patients. Crit Rev Oncol Hematol. 2005 May.54(2):137-143. Pubmedid: 15843096.
• Weitzner M, Kanfer S, Booth-Jones M. Apathy and pituitary disease: it has nothing to do with depression. J Neuropsychiatry Clin Neurosci. 2005 Apr.17(2):159-166. Pubmedid: 15939968.
• Jacobsen P, Garland L, Booth-Jones M, Donovan K, Thors C, Winters E, Grendys E. Relationship of hemoglobin levels to fatigue and cognitive functioning among cancer patients receiving chemotherapy. J Pain Symptom Manag. 2004 Jul.28(1):7-18. Pubmedid: 15223080.
• Sadler I, Jacobsen P, Booth-Jones M, Belanger H, Weitzner M, Fields K. Preliminary evaluation of a clinical syndrome approach to assessing cancer-related fatigue. J Pain Symptom Manag. 2002 May.23(5):406-416. Pubmedid: 12007758.
• Jacobsen PB, Sadler IJ, Booth-Jones M, Soety E, Weitzner MA, Fields KK. Predictors of posttraumatic stress disorder symptomatology following bone marrow transplantation for cancer. J Consult Clin Psychol. 2002 Feb.70(1):235-240. Pubmedid: 11860050.