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Mihaela Druta, MD
Specialty: Medical Oncology
Program: Sarcoma
Call 1-888-MOFFITT
(1-888-663-3488)
Call 1-888-MOFFITT
(1-888-663-3488)
Locations: Moffitt Cancer Center
Cancer Types Treated: GIST (Gastrointestinal Stromal Tumor) , Osteosarcoma , Sarcoma
Dr. Druta earned her MD degree from the University of Medicine and Pharmacy Carol Davila, Romainia. She completed an Internal Medicine Residency and Hematology/Medical Oncology Fellowship at the University of South Florida at Moffitt Cancer Center. Dr. Druta most recently completed a Sarcoma Medical Oncology Fellowship (Willie Tichenor Sarcoma Fellowship) at MD Anderson Cancer Center. Dr. Druta's clinical interest is in the development of clinical trials focusing on targeted therapeutics specific to sarcoma patients. Her research interest is in the translational aspects of sarcoma biology focusing specifically on Well-differentiated/Differential Liposarcoma and Leiomyosarcoma.
Education & Training
Board Certification:
- Internal Medicine
- Internal Medicine
Fellowship:
- H. Lee Moffitt Cancer Center - Hematology and Medical Oncology
- MD Anderson Cancer Center - Sarcoma Medical Oncology
Residency:
- University of South Florida - Internal Medicine
Medical School:
- University of Medicine and Pharmacy Carol Davilla - MD
CLINICAL TRIAL 18782
A Pilot Study Of NY-ESO-1c259T Cells In Subjects With Advanced Myxoid/ Round Cell Liposarcoma
Condition: Sarcoma
Intervention: NY-ESO-1c259T; cyclophosphamide; cytoxan (cyclophosphamide); fludarabine (Fludarabine phosphate)
Open
CLINICAL TRIAL 18119
A Phase 1b Study Evaluating the Safety, Tolerability and Immunogenicity of CMB305 (Sequentially Administered LV305 and G305) in Patients with Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1
Condition: Sarcoma
Intervention: Atezolizumab (Tecentriq); G100; G305; LV305; cyclophosphamide; cytoxan (cyclophosphamide)
Open
CLINICAL TRIAL 19504
An International, Multicenter, Open-label, Randomized, Phase 3 Study of BLU-285 vs Regorafenib in Patients with Locally Advanced Unresectable or Metastatic Gastrointestinal Stromal Tumor (GIST)
Condition: Sarcoma
Intervention: Avapritinib; BAY 73-4506 (Regorafenib); BLU-285 (Avapritinib); Not Applicable; Regorafenib (Stivarga)
Open
CLINICAL TRIAL 18613
Phase II Study of nab-Paclitaxel in Combination with Gemcitabine for Treatment of Recurrent/Refractory Sarcoma in Teenagers and Young Adults
Condition: Sarcoma
Intervention: Gemzar (gemcitabine); Nab-paclitaxel (Abraxane); gemcitabine
Open
CLINICAL TRIAL 18503
STARTRK-2: An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients with Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements
Condition: Thoracic
Intervention: Entrectinib
Open
CLINICAL TRIAL 19003
A Randomized Phase 3 Trial of TRC105 and Pazopanib versus Pazopanib Alone In Patients with Advanced Angiosarcoma (TAPPAS)
Condition: Sarcoma
Intervention: Pazopanib; TRC105 (Carotuximab)
Open
CLINICAL TRIAL 19112
DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors
Condition: Multiple
Intervention: BMS-936558 (Nivolumab); Ipilimumab; Nivolumab; Yervoy (Ipilimumab)
Open
CLINICAL TRIAL 18855
Multicenter, Open-label, Phase 1, Dose-escalation,Cohort-expansion, First-in-Human Study of KHK2455 Administered as Monotherapy and in Combination with Mogamulizumab (KW-0761) in Adult Subjects with Locally Advanced or Metastatic Solid Tumors
Condition: Multiple
Intervention: KHK2455; KW-0761 (Mogamulizumab); Mogamulizumab
Open
CLINICAL TRIAL 19480
The Reveal Study: A Phase 1/2, Open-Label, Multicenter, Dose Escalation And Dose Expansion Study Of Nktr-262 In Combination With Nktr-214 And In combination With Nktr-214 Plus Nivolumab In Patients With Locally Advanced Or Metastatic Solid Tumor Malignancies
Condition: Multiple
Intervention: BMS-936558 (Nivolumab); NKTR-214; NKTR-262; Nivolumab
Open
CLINICAL TRIAL 19365
Phase I Trial of the LSD1 inhibitor SP-2577 in Patients with Relapsed or Refractory Ewing Sarcoma
Condition: Sarcoma
Intervention: SP-2577
Open
CLINICAL TRIAL 19577
A Phase 1 Multiple Dose Study to Evaluate the Safety and Tolerability of XmAb®18087 in Subjects with Advanced Neuroendocrine and Gastrointestinal Stromal Tumors (DUET-1)
Condition: Gastrointestinal Tumor
Intervention: XmAb18087
Open
CLINICAL TRIAL 19158
A Pilot Study of Atezolizumab (MPDL3280A) Following Adoptive Cell Transfer in Active Hematologic or Solid Tumor Malignancies
Condition: Malignant Hematology
Intervention: Atezolizumab (Tecentriq)
Open
If you believe you are eligible for one of these trials or studies, please call
813-745-6100 or toll-free 1-800-679-0775.
- Pham V, Henderson-Jackson E, Doepker MP, Caracciolo JT, Gonzalez RJ, Druta M, Ding Y, Bui MM. Practical Issues for Retroperitoneal Sarcoma. Cancer Control. 2016 Jul;23(3):249-264. Pubmedid: 27556665.
- Dossett LA, Toloza EM, Fontaine J, Robinson LA, Reed D, Druta M, Letson DG, Zager JS, Gonzalez RJ. Outcomes and clinical predictors of improved survival in a patients undergoing pulmonary metastasectomy for sarcoma. J Surg Oncol. 2015 Jul;112(1):103-106. Pubmedid: 26179670.
- Liu JJ, Druta M, Shibata D, Coppola D, Boler I, Elahi A, Reich RR, Siegel E, Extermann M. Metabolic syndrome and colorectal cancer: is hyperinsulinemia/insulin receptor-mediated angiogenesis a critical process?. Geriatr Oncol. 2014 Jan;5(1):40-48. Pubmedid: 24484717. Pmcid: PMC4527303.
- Helm J, Centeno B, Coppola D, Druta M, Park J, Chen D, Hodul P, Kvols LK, Yeatman T, Carey L, Karl R, Malafa M. Outcomes following resection of pancreatic adenocarcinoma: 20-year experience at a single institution. Cancer Control. 2008 Oct;15(4):288-294. Pubmedid: 18813196.
- Jacobsen PB, Shibata D, Siegel EM, Druta M, Lee JH, Marshburn J, Davenport L, Cruse H, Levine R, Gondi A, Brown R, Malafa M. Measuring quality of care in the treatment of colorectal cancer: the moffitt quality practice initiative. J Oncol Pract. 2007 Mar;3(2):60-65. Pubmedid: 20859375. Pmcid: PMC2793747.
