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Jonathan S. Zager, MD

Specialty: Surgery
Program: Cutaneous Oncology

Call 1-888-MOFFITT

or call 1-888-MOFFITT


Dr. Jonathan Zager is the Chair of Graduate Medical Education and a surgical oncologist and Senior Member in the Departments of Cutaneous Oncology and Sarcoma at Moffitt Cancer Center and Director of Regional Therapies at Moffitt’s Donald A. Adam Comprehensive Melanoma Research Center. Dr. Zager is a Professor of Surgery at the University of South Florida, Morasani School of Medicine. Dr. Zager’s research and clinical interests include the regional therapy treatment of cutaneous melanoma and non-melanoma skin cancers, soft tissue sarcomas. Dr. Zager has extensively studied and performed isolated limb infusions for in transit or recurrent extremity melanoma and unresectable extremity sarcomas and percutaneous hepatic perfusions for unresectable melanoma to the liver. Dr. Zager graduated magna cum laude from Sackler School of Medicine’s New York State/American Program. He served a junior residency at North Shore University Hospital-New York University School of Medicine and was a research fellow at Memorial-Sloan Kettering Cancer Center before completing residency in surgery at Montefiore Medical Center-Albert Einstein College of Medicine. He was chief resident his last year. Dr. Zager completed fellowship training in surgical oncology at the University of Texas-M.D. Anderson Cancer Center. Dr. Zager has received numerous awards, including Best Doctors in America, America’s Top Oncologists, Castle Connolly Top Doctors, and Patients Choice Physician Awards. He is a member of numerous editorial and advisory boards and professional organizations, including the Sentinel Node Oncology Foundation executive committee as well as the Chair of the Melanoma/Sarcoma Disease Site Working Group in the Society of Surgical Oncology. Dr. Zager is the Director of Student Research in the Department of Cutaneous Oncology including the 8 week Summer Student Research Internship.

Education & Training

Board Certification:

  • Surgery


  • Memorial-Sloan Kettering Cancer Center - Hepatobiliary Oncology Laboratory
  • University of Texas, M.D. Anderson Cancer Center - Surgical Oncology
  • University of Texas, M.D. Anderson Cancer Center - Administrative Fellow


  • Montefiore Medical Center - Albert Einstein College of Medicine - Department of Surgery

Medical School:

  • Sackler School of Medicine - New York State American Program - MD
Participating Trials

A Randomized, Controlled, Phase 3 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Melphalan/HDS Treatment in Patients with Hepatic-Dominant Ocular Melanoma
Condition: Cutaneous
Intervention: Alkeran (Melphalan); DTIC (Dacarbazine); Dacarbazine; Ipilimumab; Melphalan; Pembrolizumab (Keytruda); Yervoy (Ipilimumab)

A Phase 1b/2 Study of PV-10 Intralesional Injection in Combination with Systemic Immune Checkpoint Inhibition for Treatment of Metastatic Melanoma
Condition: Cutaneous
Intervention: PV-10; Pembrolizumab (Keytruda)

A Phase 2, Multicenter, Single-arm Study to Assess the Safety, Feasibility, and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-144) Followed by IL-2 for Treatment of Metastatic Melanoma
Condition: Cutaneous
Intervention: Aldesleukin (Interleukin-2); IL-2 (Interleukin-2); Interleukin-2; Proleukin (Interleukin-2); TIL

A Pilot Clinical Trial Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma
Condition: Cutaneous
Intervention: Aldesleukin (Interleukin-2); BMS-936558 (Nivolumab); IL-2 (Interleukin-2); Interleukin-2; Nivolumab; Proleukin (Interleukin-2); TIL

Phase I Study of Escalating Doses of XL888 with Vemurafenib plus Cobimetinib for Patients with Unresectable BRAF Mutated Stage III/IV Melanoma
Condition: Cutaneous
Intervention: Cobimetinib; RO5185426 (Vemurafenib); Vemurafenib (Zelboraf); XL888

If you believe you are eligible for one of these trials or studies, please call
1-888-MOFFITT (1-888-663-3488).


  • Sloot S, Chen YA, Zhao X, Weber JL, Benedict JJ, Mulé JJ, Smalley KS, Weber JS, Zager JS, Forsyth PA, Sondak VK, Gibney GT. Improved survival of patients with melanoma brain metastases in the era of targeted BRAF and immune checkpoint therapies. Cancer. 2018 Jan;124(2):297-305. Pubmedid: 29023643.
  • Perez MC, Orcutt ST, Zager JS. Current standards of surgical management in primary melanoma. G Ital Dermatol Venereol. 2018 Feb;153(1):56-67. Pubmedid: 28895666.
  • Wong SL, Faries MB, Kennedy EB, Agarwala SS, Akhurst TJ, Ariyan C, Balch CM, Berman BS, Cochran A, Delman KA, Gorman M, Kirkwood JM, Moncrieff MD, Zager JS, Lyman GH. Sentinel Lymph Node Biopsy and Management of Regional Lymph Nodes in Melanoma: American Society of Clinical Oncology and Society of Surgical Oncology Clinical Practice Guideline Update. Ann Surg Oncol. 2018 Feb;25(2):356-377. Pubmedid: 29236202.
  • Sondak VK, Messina JL, Zager JS. Selecting Patients With Thin Melanoma for Sentinel Lymph Node Biopsy-This Time It's Personal. JAMA Dermatol. 2017 Sep;153(9):857-858. Pubmedid: 28724141.
  • Rossfeld K, Hade EM, Gangi A, Perez M, Kinsey EN, Grabska J, Ederle A, Zager J, Salama AK, Olencki TE, Beasley GM. Metastatic melanoma patients' sensitivity to ipilimumab cannot be predicted by tumor characteristics. Int J Surg Oncol (N Y). 2017 Oct;2(9):e43. Pubmedid: 29177235. Pmcid: PMC5673131.
  • Schuitevoerder D, Leong SPL, Zager JS, White RL, Avisar E, Kosiorek H, Dueck A, Fortino J, Kashani-Sabet M, Hart K, Vetto JT. Is pelvic sentinel node biopsy necessary for lower extremity and trunk melanomas?. Am J Surg. 2017 May;213(5):921-925. Pubmedid: 28411863.
  • Glazer ES, Porubsky CF, Francis JD, Ibanez J, Castner N, Messina JL, Sarnaik AA, Harrington MA, Cruse CW, Sondak VK, Zager JS. Treatment of Head and Neck Melanoma In Situ With Staged Contoured Marginal Excisions. Ann Plast Surg. 2017 Jun;78(6):663-667. Pubmedid: 27984218. Pmcid: PMC5425303.
  • Faries MB, Thompson JF, Cochran AJ, Andtbacka RH, Mozzillo N, Zager JS, Jahkola T, Bowles TL, Testori A, Beitsch PD, Hoekstra HJ, Moncrieff M, Ingvar C, Wouters MWJM, Sabel MS, Levine EA, Agnese D, Henderson M, Dummer R, Rossi CR, Neves RI, Trocha SD, Wright F, Byrd DR, Matter M, Hsueh E, MacKenzie-Ross A, Johnson DB, Terheyden P, Berger AC, Huston TL, Wayne JD, Smithers BM, Neuman HB, Schneebaum S, Gershenwald JE, Ariyan CE, Desai DC, Jacobs L, McMasters KM, Gesierich A, Hersey P, Bines SD, Kane JM, Barth RJ, McKinnon G, Farma JM, Schultz E, Vidal-Sicart S, Hoefer RA, Lewis JM, Scheri R, Kelley MC, Nieweg OE, Noyes RD, Hoon DSB, Wang HJ, Elashoff DA, Elashoff RM. Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma. N Engl J Med. 2017 Jun;376(23):2211-2222. Pubmedid: 28591523. Pmcid: PMC5548388.
  • DePeralta DK, Zager JS. Metastasectomy for Abdominal Visceral Oligometastatic Melanoma. JAMA Surg. 2017 Jul;152(7):678. Pubmedid: 28384678.
  • Abbott AM, Doepker MP, Kim Y, Perez MC, Gandle C, Thomas KL, Choi J, Shridhar R, Zager JS. Hepatic Progression-free and Overall Survival After Regional Therapy to the Liver for Metastatic Melanoma. Am J Clin Oncol. 2017 Jan. Pubmedid: 28059929.
  • Glazer ES, Zager JS. Chemosaturation With Percutaneous Hepatic Perfusion in Unresectable Hepatic Metastases. Cancer Control. 2017 Jan;24(1):96-101. Pubmedid: 28178721.
  • Gangi A, Zager JS. The safety of talimogene laherparepvec for the treatment of advanced melanoma. Expert Opin Drug Saf. 2017 Feb;16(2):265-269. Pubmedid: 27989216.
  • Doepker MP, Yamamoto M, Applebaum MA, Patel NU, Jaime Montilla-Soler M, Sarnaik AA, Wayne Cruse C, Sondak VK, Zager JS. Comparison of Single-Photon Emission Computed Tomography-Computed Tomography (SPECT/CT) and Conventional Planar Lymphoscintigraphy for Sentinel Node Localization in Patients with Cutaneous Malignancies. Ann Surg Oncol. 2017 Feb;24(2):355-361. Pubmedid: 27660259.
  • O'Donoghue C, Perez MC, Mullinax JE, Hardman D, Sileno S, Naqvi SMH, Kim Y, Gonzalez RJ, Zager JS. Isolated Limb Infusion: A Single-Center Experience with Over 200 Infusions. Ann Surg Oncol. 2017 Dec;24(13):3842-3849. Pubmedid: 29019175.
  • Chai C, Szabunio M, Cook C, Zager J, Messina J, Chau A, Sondak V. Pre-SN Ultrasound-FNAC for Lymph Node Metastases in Melanoma Patients: A Reply. Ann Surg Oncol. 2017 Dec;24(Suppl 3):663-664. Pubmedid: 29134381.
  • Neuwirth MG, Song Y, Sinnamon AJ, Fraker DL, Zager JS, Karakousis GC. Isolated Limb Perfusion and Infusion for Extremity Soft Tissue Sarcoma: A Contemporary Systematic Review and Meta-Analysis. Ann Surg Oncol. 2017 Dec;24(13):3803-3810. Pubmedid: 29022281.
  • Karydis I, Gangi A, Wheater MJ, Choi J, Wilson I, Thomas K, Pearce N, Takhar A, Gupta S, Hardman D, Sileno S, Stedman B, Zager JS, Ottensmeier C. Percutaneous hepatic perfusion with melphalan in uveal melanoma: A safe and effective treatment modality in an orphan disease. J Surg Oncol. 2017 Dec. Pubmedid: 29284076.
  • Wong SL, Faries MB, Kennedy EB, Agarwala SS, Akhurst TJ, Ariyan C, Balch CM, Berman BS, Cochran A, Delman KA, Gorman M, Kirkwood JM, Moncrieff MD, Zager JS, Lyman GH. Sentinel Lymph Node Biopsy and Management of Regional Lymph Nodes in Melanoma: American Society of Clinical Oncology and Society of Surgical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2017 Dec. Pubmedid: 29232171.
  • Weitman ES, Perez M, Thompson JF, Andtbacka RHI, Dalton J, Martin ML, Miller T, Gwaltney C, Sarson D, Wachter E, Zager JS. Quality of life patient-reported outcomes for locally advanced cutaneous melanoma. Melanoma Res. 2017 Dec. Pubmedid: 29261570.
  • Mullinax JE, Gonzalez RJ, Zager JS. Treatment of Soft Tissue Sarcoma: In reply to He and colleagues. J Am Coll Surg. 2017 Aug;225(2):349. Pubmedid: 28750715.
  • Jones MS, Jones PC, Stern SL, Elashoff D, Hoon DS, Thompson J, Mozzillo N, Nieweg OE, Noyes D, Hoekstra HJ, Zager JS, Roses DF, Testori A, Coventry BJ, Smithers MB, Andtbacka R, Agnese D, Schultz E, Hsueh EC, Kelley M, Schneebaum S, Jacobs L, Bowles T, Kashani-Sabet M, Johnson D, Faries MB. The Impact of Smoking on Sentinel Node Metastasis of Primary Cutaneous Melanoma. Ann Surg Oncol. 2017 Aug;24(8):2089-2094. Pubmedid: 28224364. Pmcid: PMC5553293.
  • Strom T, Torres-Roca JF, Parekh A, Naghavi AO, Caudell JJ, Oliver DE, Messina JL, Khushalani NI, Zager JS, Sarnaik A, Mulé JJ, Trotti AM, Eschrich SA, Sondak VK, Harrison LB. Regional Radiation Therapy Impacts Outcome for Node-Positive Cutaneous Melanoma. J Natl Compr Canc Ne. 2017 Apr;15(4):473-482. Pubmedid: 28404758.
  • Mullinax JE, Kroon HM, Thompson JF, Nath N, Mosca PJ, Farma JM, Bhati R, Hardmann D, Sileno S, O'Donoghue C, Perez M, Naqvi SM, Chen YA, Gonzalez RJ, Zager JS. Isolated Limb Infusion as a Limb Salvage Strategy for Locally Advanced Extremity Sarcoma. J Am Coll Surg. 2017 Apr;224(4):635-642. Pubmedid: 28214556.
  • Zimmer L, Apuri S, Eroglu Z, Kottschade LA, Forschner A, Gutzmer R, Schlaak M, Heinzerling L, Krackhardt AM, Loquai C, Markovic SN, Joseph RW, Markey K, Utikal JS, Weishaupt C, Goldinger SM, Sondak VK, Zager JS, Schadendorf D, Khushalani NI. Ipilimumab alone or in combination with nivolumab after progression on anti-PD-1 therapy in advanced melanoma. Eur J Cancer. 2017 Apr;75:47-55. Pubmedid: 28214657.
  • Sarnaik AA, Zager JS, Sondak VK. Point: Surgical Management of Lymph Node Basin in Sentinel Lymph Node-Positive Melanoma. Oncology (Williston Park). 2016 Oct;30(10):891-2-895. Pubmedid: 27753054.
  • Strom T, Carr M, Zager JS, Naghavi A, Smith FO, Cruse CW, Messina JL, Russell J, Rao NG, Fulp W, Kim S, Torres-Roca JF, Padhya TA, Sondak VK, Trotti AM, Harrison LB, Caudell JJ. Radiation Therapy is Associated with Improved Outcomes in Merkel Cell Carcinoma. Ann Surg Oncol. 2016 Oct;23(11):3572-3578. Pubmedid: 27251134.
  • Parekh A, Strom T, Naghavi AO, Caudell JJ, Zager JS, Messina JL, Torres-Roca JF, Sondak VK, Trotti A, Harrison LB. Does Regional Radiation Therapy Impact Outcome for High-Risk, Node-Positive Cutaneous Melanoma?. Int J Radiat Oncol Biol Phys. 2016 Oct;96(2S):S157. Pubmedid: 27675666.
  • Prabhakaran S, Fulp WJ, Gonzalez RJ, Sondak VK, Kudchadkar RR, Gibney GT, Weber JS, Zager JS. Resection of Gastrointestinal Metastases in Stage IV Melanoma: Correlation with Outcomes. Am Surg. 2016 Nov;82(11):1109-1116. Pubmedid: 28206940.
  • Prabhakaran S, Fulp WJ, Gonzalez RJ, Sondak VK, Kudchadkar RR, Gibney GT, Weber JS, Zager JS. Resection of Gastrointestinal Metastases in Stage IV Melanoma: Correlation with Outcomes. Am Surg. 2016 Nov;82(11):1109-1116. Pubmedid: 28877811.
  • Naghavi AO, Gonzalez RJ, Scott JG, Mullinax JE, Abuodeh YA, Kim Y, Binitie O, Ahmed KA, Bui MM, Saini AS, Zager JS, Biagioli MC, Letson D, Harrison LB, Fernandez DC. Implications of staged reconstruction and adjuvant brachytherapy in the treatment of recurrent soft tissue sarcoma. Brachytherapy. 2016 Jul;15(4):495-503. Pubmedid: 27180128.
  • Dossett LA, Ben-Shabat I, Olofsson Bagge R, Zager JS. Clinical Response and Regional Toxicity Following Isolated Limb Infusion Compared with Isolated Limb Perfusion for In-Transit Melanoma. Ann Surg Oncol. 2016 Jul;23(7):2330-2335. Pubmedid: 26926481.
  • Doepker MP, Thompson ZJ, Fisher KJ, Yamamoto M, Nethers KW, Harb JN, Applebaum MA, Gonzalez RJ, Sarnaik AA, Messina JL, Sondak VK, Zager JS. Is a Wider Margin (2 cm vs. 1 cm) for a 1.01-2.0 mm Melanoma Necessary?. Ann Surg Oncol. 2016 Jul;23(7):2336-2342. Pubmedid: 26957503. Pmcid: PMC4904729.
  • Doepker MP, Thompson ZJ, Harb JN, Messina JL, Puleo CA, Egan KM, Sarnaik AA, Gonzalez RJ, Sondak VK, Zager JS. Dermal melanoma: A report on prognosis, outcomes, and the utility of sentinel lymph node biopsy. J Surg Oncol. 2016 Jan;113(1):98-102. Pubmedid: 26661407. Pmcid: PMC4904728.
  • Otto K, Zager JS. Art, Science, and Personalized Cancer Care Through Regional Therapeutics. Cancer Control. 2016 Jan;23(1):3-4. Pubmedid: 27009450.
  • Sloot S, Rashid OM, Sarnaik AA, Zager JS. Developments in Intralesional Therapy for Metastatic Melanoma. Cancer Control. 2016 Jan;23(1):12-20. Pubmedid: 27009452. Pmcid: PMC4904721.
  • Sloot S, Zager JS, Kudchadkar RR, Messina JL, Benedict JJ, Gonzalez RJ, DeConti R, Turner LM, McCardle T, Smalley KS, Weber JS, Sondak VK, Gibney GT. BRAF inhibition for advanced locoregional BRAF V600E mutant melanoma: a potential neoadjuvant strategy. Melanoma Res. 2016 Feb;26(1):83-87. Pubmedid: 26731560.
  • Luu C, Khushalani NI, Zager JS. Intralesional and systemic immunotherapy for metastatic melanoma. Expert Opin Biol Ther. 2016 Dec;16(12):1491-1499. Pubmedid: 27602429.
  • Andtbacka RH, Ross M, Puzanov I, Milhem M, Collichio F, Delman KA, Amatruda T, Zager JS, Cranmer L, Hsueh E, Chen L, Shilkrut M, Kaufman HL. Patterns of Clinical Response with Talimogene Laherparepvec (T-VEC) in Patients with Melanoma Treated in the OPTiM Phase III Clinical Trial. Ann Surg Oncol. 2016 Dec;23(13):4169-4177. Pubmedid: 27342831. Pmcid: PMC5090012.
  • Hassani J, Porubsky C, Berman C, Zager J, Messina J, Henderson-Jackson E. Intraperitoneal Rosai-Dorfman disease associated with clear cell sarcoma: first case report. Pathology. 2016 Dec;48(7):742-744. Pubmedid: 27814905.
  • Dossett LA, Castner NB, Pow-Sang JM, Abbott AM, Sondak VK, Sarnaik AA, Zager JS. Robotic-Assisted Transperitoneal Pelvic Lymphadenectomy for Metastatic Melanoma: Early Outcomes Compared with Open Pelvic Lymphadenectomy. J Am Coll Surg. 2016 Apr;222(4):702-709. Pubmedid: 26875071. Pmcid: PMC4871144.
  • Hughes MS, Zager J, Faries M, Alexander HR, Royal RE, Wood B, Choi J, McCluskey K, Whitman E, Agarwala S, Siskin G, Nutting C, Toomey MA, Webb C, Beresnev T, Pingpank JF. Results of a Randomized Controlled Multicenter Phase III Trial of Percutaneous Hepatic Perfusion Compared with Best Available Care for Patients with Melanoma Liver Metastases. Ann Surg Oncol. 2016 Apr;23(4):1309-1319. Pubmedid: 26597368.
  • Andtbacka RH, Kaufman HL, Collichio F, Amatruda T, Senzer N, Chesney J, Delman KA, Spitler LE, Puzanov I, Agarwala SS, Milhem M, Cranmer L, Curti B, Lewis K, Ross M, Guthrie T, Linette GP, Daniels GA, Harrington K, Middleton MR, Miller WH, Zager JS, Ye Y, Yao B, Li A, Doleman S, VanderWalde A, Gansert J, Coffin RS. Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma. J Clin Oncol. 2015 Sep;33(25):2780-2788. Pubmedid: 26014293.
  • Smith FO, Yue B, Marzban SS, Walls BL, Carr M, Jackson RS, Puleo CA, Padhya T, Cruse CW, Gonzalez RJ, Sarnaik AA, Schell MJ, DeConti RC, Messina JL, Sondak VK, Zager JS. Both tumor depth and diameter are predictive of sentinel lymph node status and survival in Merkel cell carcinoma. Cancer. 2015 Sep;121(18):3252-3260. Pubmedid: 26038193. Pmcid: PMC4904725.
  • Rashid OM, Zager JS. Genetic Testing in the Multidisciplinary Management of Melanoma. Surg Oncol Clin N Am. 2015 Oct;24(4):779-793. Pubmedid: 26363541.
  • DeVito N, Henderson E, Han G, Reed D, Bui MM, Lavey R, Robinson L, Zager JS, Gonzalez RJ, Sondak VK, Letson GD, Conley A. Clinical Characteristics and Outcomes for Solitary Fibrous Tumor (SFT): A Single Center Experience. PLoS One. 2015 Oct;10(10):e0140362. Pubmedid: 26469269. Pmcid: PMC4607370.
  • Yamamoto M, Fisher KJ, Wong JY, Koscso JM, Konstantinovic MA, Govsyeyev N, Messina JL, Sarnaik AA, Cruse CW, Gonzalez RJ, Sondak VK, Zager JS. Sentinel lymph node biopsy is indicated for patients with thick clinically lymph node-negative melanoma. Cancer. 2015 May;121(10):1628-1636. Pubmedid: 25677366. Pmcid: PMC4515965.
  • Han D, Han G, Zhao X, Rao NG, Messina JL, Marzban SS, Sarnaik AA, Cruse CW, Sondak VK, Zager JS. Clinicopathologic predictors of survival in patients with desmoplastic melanoma. PLoS One. 2015 Mar;10(3):e0119716. Pubmedid: 25811671. Pmcid: PMC4374691.
  • Dossett LA, Toloza EM, Fontaine J, Robinson LA, Reed D, Druta M, Letson DG, Zager JS, Gonzalez RJ. Outcomes and clinical predictors of improved survival in a patients undergoing pulmonary metastasectomy for sarcoma. J Surg Oncol. 2015 Jul;112(1):103-106. Pubmedid: 26179670.
  • Beasley GM, Speicher P, Augustine CK, Dolber PC, Peterson BL, Sharma K, Mosca PJ, Royal R, Ross M, Zager JS, Tyler DS. A multicenter phase I dose escalation trial to evaluate safety and tolerability of intra-arterial temozolomide for patients with advanced extremity melanoma using normothermic isolated limb infusion. Ann Surg Oncol. 2015 Jan;22(1):287-294. Pubmedid: 25145500. Pmcid: PMC4464816.
  • Muilenburg DJ, Beasley GM, Thompson ZJ, Lee JH, Tyler DS, Zager JS. Burden of disease predicts response to isolated limb infusion with melphalan and actinomycin D in melanoma. Ann Surg Oncol. 2015 Feb;22(2):482-488. Pubmedid: 25192683. Pmcid: PMC4505812.
  • Glazer ES, Prieto-Granada C, Zager JS. Current approaches to cutaneous sarcomas: Dermatofibrosarcoma protuberans and cutaneous leiomyosarcoma. Curr Prob Cancer. 2015 Aug;39(4):248-257. Pubmedid: 26276213.
  • Doepker MP, Zager JS. Sentinel Lymph Node Mapping in Melanoma in the Twenty-first Century. Surg Oncol Clin N Am. 2015 Apr;24(2):249-260. Pubmedid: 25769710.
  • Dossett LA, Kudchadkar RR, Zager JS. BRAF and MEK inhibition in melanoma. Expert Opin Drug Saf. 2015 Apr;14(4):559-570. Pubmedid: 25648338.
  • Rashid OM, Sloot S, Zager JS. Regional therapy in metastatic melanoma: an update on minimally invasive intraarterial isolated limb infusion and percutaneous hepatic perfusion. Expert Opin Drug Metab Toxicol. 2014 Oct;10(10):1355-1364. Pubmedid: 25176398.
  • Abbott AM, Zager JS. Locoregional therapies in melanoma. Surg Clin N Am. 2014 Oct;94(5):1003-15, viii. Pubmedid: 25245964.
  • Strom T, Caudell JJ, Han D, Zager JS, Yu D, Cruse CW, Marzban SS, Messina JL, Trotti AM, Sondak VK, Rao NG. Radiotherapy influences local control in patients with desmoplastic melanoma. Cancer. 2014 May;120(9):1369-1378. Pubmedid: 24142775. Pmcid: PMC4515972.
  • Linden KG, Leachman SA, Zager JS, Jakowatz JG, Viner JL, McLaren CE, Barr RJ, Carpenter PM, Chen WP, Elmets CA, Tangrea J, Lim SJ, Cochran AJ, Meyskens FL. A randomized, double-blind, placebo-controlled phase II clinical trial of lovastatin for various endpoints of melanoma pathobiology. Cancer Prev Res (Phila). 2014 May;7(5):496-504. Pubmedid: 24614012. Pmcid: PMC4208700.
  • Sondak VK, Zager JS. Melanoma: MSLT-1--putting sentinel lymph node biopsy into context. Nat Rev Clin Oncol. 2014 May;11(5):246-248. Pubmedid: 24732944.
  • Zager JS, Messina JL, Glass LF, Sondak VK. Unanswered Questions in the Management of Stage I-III Merkel Cell Carcinoma. J Natl Compr Canc Ne. 2014 Mar;12(3):425-431. Pubmedid: 24616546.
  • Agarwala SS, Eggermont AM, O'Day S, Zager JS. Metastatic melanoma to the liver: a contemporary and comprehensive review of surgical, systemic, and regional therapeutic options. Cancer. 2014 Mar;120(6):781-789. Pubmedid: 24301420.
  • Toloza E, Rodriguez K, Sobky C, Brown L, Garrett J, Chai C, Moodie C, Bhati R, Mosiello G, Zager J. Interclavicular stabilization with the synthes sternal fixation system after radical manubriectomy: report of 3 cases. Chest. 2014 Mar;145(3 Suppl):35A. Pubmedid: 24638364.
  • Yamamoto M, Zager JS. Isolated hepatic perfusion for metastatic melanoma. J Surg Oncol. 2014 Mar;109(4):383-388. Pubmedid: 24166748.
  • Ettinger DS, Handorf CR, Agulnik M, Bowles DW, Cates JM, Cristea M, Dotan E, Eaton KD, Fidias PM, Gierada D, Gilcrease GW, Godby K, Iyer R, Lenzi R, Phay J, Rashid A, Saltz L, Schwab RB, Shulman LN, Smerage JB, Stevenson MM, Varadhachary GR, Zager JS, Zhen WK, Bergman MA, Freedman-Cass DA. Occult primary, version 3.2014. J Natl Compr Canc Ne. 2014 Jul;12(7):969-974. Pubmedid: 24994917.
  • Thareja S, Zager JS, Sadhwani D, Thareja S, Chen R, Marzban S, Jukic DM, Glass LF, Messina J. Analysis of tumor mitotic rate in thin metastatic melanomas compared with thin melanomas without metastasis using both the hematoxylin and eosin and anti-phosphohistone 3 IHC stain. Am J Dermatopathxxx. 2014 Jan;36(1):64-67. Pubmedid: 24451214. Pmcid: PMC5764097.
  • Wong J, Ann Chen Y, Fisher KJ, Beasley GM, Tyler DS, Zager JS. Resection of residual disease after isolated limb infusion (ILI) is equivalent to a complete response after ILI-alone in advanced extremity melanoma. Ann Surg Oncol. 2014 Feb;21(2):650-655. Pubmedid: 24162840. Pmcid: PMC4504422.
  • Sloot S, Rashid OM, Zager JS. Intralesional therapy for metastatic melanoma. Expert Opin Pharmacother. 2014 Dec;15(18):2629-2639. Pubmedid: 25381015.
  • Saranga-Perry V, Ambe C, Zager JS, Kudchadkar RR. Recent developments in the medical and surgical treatment of melanoma. CA-Cancer J Clin. 2014 Aug;64(3):171-185. Pubmedid: 24676837.
  • Forster MR, Rashid OM, Perez MC, Choi J, Chaudhry T, Zager JS. Chemosaturation with percutaneous hepatic perfusion for unresectable metastatic melanoma or sarcoma to the liver: a single institution experience. J Surg Oncol. 2014 Apr;109(5):434-439. Pubmedid: 24249545. Pmcid: PMC4503311.
  • de la Fuente SG, Deneve JL, Parsons CM, Zager JS, Conley AP, Gonzalez RJ. A comparison between patients with gastrointestinal stromal tumours diagnosed with isolated liver metastases and liver metastases plus sarcomatosis. HPB (Oxford). 2013 Sep;15(9):655-660. Pubmedid: 23458233. Pmcid: PMC3948531.
  • Deneve JL, Messina JL, Bui MM, Marzban SS, Letson GD, Cheong D, Gonzalez RJ, Sondak VK, Zager JS. Cutaneous leiomyosarcoma: treatment and outcomes with a standardized margin of resection. Cancer Control. 2013 Oct;20(4):307-312. Pubmedid: 24077407. Pmcid: PMC4504421.
  • Perez MC, Padhya TA, Messina JL, Jackson RS, Gonzalez RJ, Bui MM, Letson GD, Cruse CW, Lavey RS, Cheong D, Forster MR, Fulp WJ, Sondak VK, Zager JS. Cutaneous angiosarcoma: a single-institution experience. Ann Surg Oncol. 2013 Oct;20(11):3391-3397. Pubmedid: 23835652. Pmcid: PMC4509495.
  • Etzkorn JR, Parikh RP, Marzban SS, Law K, Davis AH, Rawal B, Schell MJ, Sondak VK, Messina JL, Rendina LE, Zager JS, Lien MH. Identifying risk factors using a skin cancer screening program. Cancer Control. 2013 Oct;20(4):248-254. Pubmedid: 24077401. Pmcid: PMC4516026.
  • Zager JS, Sarnaik AA, Gibney GT, Kudchadkar RR. Recent advances in the treatment of melanoma. Cancer Control. 2013 Oct;20(4):244-245. Pubmedid: 24077400.
  • Deneve JL, Turaga KK, Marzban SS, Puleo CA, Sarnaik AA, Gonzalez RJ, Sondak VK, Zager JS. Single-institution outcome experience using AlloDerm® as temporary coverage or definitive reconstruction for cutaneous and soft tissue malignancy defects. Am Surg. 2013 May;79(5):476-482. Pubmedid: 23635582. Pmcid: PMC4505800.
  • Reed D, Kudchadkar R, Zager JS, Sondak VK, Messina JL. Controversies in the evaluation and management of atypical melanocytic proliferations in children, adolescents, and young adults. J Natl Compr Canc Ne. 2013 Jun;11(6):679-686. Pubmedid: 23744867. Pmcid: PMC4530628.
  • Vohra NA, Turaga KK, Gonzalez RJ, Conley A, Reed D, Bui MM, Cheong D, Letson DG, Zager JS. The use of isolated limb infusion in limb threatening extremity sarcomas. Int J Hyperthermia. 2013 Jun;29(1):1-7. Pubmedid: 23205633. Pmcid: PMC4509503.
  • Han D, Zager JS, Yu D, Zhao X, Walls B, Marzban SS, Rao NG, Sondak VK, Messina JL. Desmoplastic melanoma: is there a role for sentinel lymph node biopsy?. Ann Surg Oncol. 2013 Jul;20(7):2345-2351. Pubmedid: 23389470. Pmcid: PMC4503324.
  • Gibney GT, Zager JS. Clinical development of dabrafenib in BRAF mutant melanoma and other malignancies. Expert Opin Drug Metab Toxicol. 2013 Jul;9(7):893-899. Pubmedid: 23621583.
  • Sondak VK, King DW, Zager JS, Schneebaum S, Kim J, Leong SP, Faries MB, Averbook BJ, Martinez SR, Puleo CA, Messina JL, Christman L, Wallace AM. Combined analysis of phase III trials evaluating [⁹⁹mTc]tilmanocept and vital blue dye for identification of sentinel lymph nodes in clinically node-negative cutaneous melanoma. Ann Surg Oncol. 2013 Feb;20(2):680-688. Pubmedid: 23054107. Pmcid: PMC3560941.
  • Han D, Zager JS, Shyr Y, Chen H, Berry LD, Iyengar S, Djulbegovic M, Weber JL, Marzban SS, Sondak VK, Messina JL, Vetto JT, White RL, Pockaj B, Mozzillo N, Charney KJ, Avisar E, Krouse R, Kashani-Sabet M, Leong SP. Clinicopathologic predictors of sentinel lymph node metastasis in thin melanoma. J Clin Oncol. 2013 Dec;31(35):4387-4393. Pubmedid: 24190111.
  • Anic GM, Sondak VK, Messina JL, Fenske NA, Zager JS, Cherpelis BS, Lee JH, Fulp WJ, Epling-Burnette PK, Park JY, Rollison DE. Telomere length and risk of melanoma, squamous cell carcinoma, and basal cell carcinoma. Cancer Epidemiol. 2013 Aug;37(4):434-439. Pubmedid: 23523330. Pmcid: PMC3679277.
  • Wong J, Chen YA, Fisher KJ, Zager JS. Isolated limb infusion in a series of over 100 infusions: a single-center experience. Ann Surg Oncol. 2013 Apr;20(4):1121-1127. Pubmedid: 23456376. Pmcid: PMC4504423.
  • Farma JM, Zager JS, Barnica-Elvir V, Puleo CA, Marzban SS, Rollison DE, Messina JL, Sondak VK. A collision of diseases: chronic lymphocytic leukemia discovered during lymph node biopsy for melanoma. Ann Surg Oncol. 2013 Apr;20(4):1360-1364. Pubmedid: 23179994. Pmcid: PMC4606461.
  • Pilon-Thomas S, Kuhn L, Ellwanger S, Janssen W, Royster E, Marzban S, Kudchadkar R, Zager J, Gibney G, Sondak VK, Weber J, Mulé JJ, Sarnaik AA. Efficacy of adoptive cell transfer of tumor-infiltrating lymphocytes after lymphopenia induction for metastatic melanoma. J Immunother. 2012 Oct;35(8):615-620. Pubmedid: 22996367. Pmcid: PMC4467830.
  • Sondak VK, Zager JS, Messina JL. Primary tumor thickness as a prognostic factor in merkel cell carcinoma: the next big thing?. Ann Surg Oncol. 2012 Oct;19(11):3307-3309. Pubmedid: 22825775.
  • Leong SP, Mihm MC, Murphy GF, Hoon DS, Kashani-Sabet M, Agarwala SS, Zager JS, Hauschild A, Sondak VK, Guild V, Kirkwood JM. Progression of cutaneous melanoma: implications for treatment. Clin Exp Metastas. 2012 Oct;29(7):775-796. Pubmedid: 22892755. Pmcid: PMC4311146.
  • Han D, Yu D, Zhao X, Marzban SS, Messina JL, Gonzalez RJ, Wayne Cruse C, Sarnaik AA, Puleo C, Sondak VK, Zager JS. Sentinel node biopsy is indicated for thin melanomas ≥0.76 mm. Ann Surg Oncol. 2012 Oct;19(11):3335-3342. Pubmedid: 22766986. Pmcid: PMC4504019.
  • Leong SP, Mihm MC, Murphy GF, Hoon DS, Kashani-Sabet M, Agarwala SS, Zager JS, Hauschild A, Sondak VK, Guild V, Kirkwood JM. Erratum to: Progression of cutaneous melanoma: implications for treatment. Clin Exp Metastasis. 2012 Oct;29(7):797-799. Pubmedid: 23053741.
  • Han D, Zager JS, Han G, Marzban SS, Puleo CA, Sarnaik AA, Reed D, Messina JL, Sondak VK. The unique clinical characteristics of melanoma diagnosed in children. Ann Surg Oncol. 2012 Nov;19(12):3888-3895. Pubmedid: 22864798. Pmcid: PMC4519977.
  • Chai CY, Deneve JL, Beasley GM, Marzban SS, Chen YA, Rawal B, Grobmyer SR, Hochwald SN, Tyler DS, Zager JS. A multi-institutional experience of repeat regional chemotherapy for recurrent melanoma of extremities. Ann Surg Oncol. 2012 May;19(5):1637-1643. Pubmedid: 22143576. Pmcid: PMC4515968.
  • Mills OL, Marzban S, Zager JS, Sondak VK, Messina JL. Sentinel node biopsy in atypical melanocytic neoplasms in childhood: a single institution experience in 24 patients. J Cutan Pathol. 2012 Mar;39(3):331-336. Pubmedid: 22335592.
  • Deneve JL, Messina JL, Marzban SS, Gonzalez RJ, Walls BM, Fisher KJ, Ann Chen Y , Wayne Cruse C, Sondak VK, Zager JS. Merkel cell carcinoma of unknown primary origin. Ann Surg Oncol. 2012 Jul;19(7):2360-2366. Pubmedid: 22271206. Pmcid: PMC4504007.
  • Parsons CM, Pimiento JM, Cheong D, Marzban SS, Gonzalez RJ, Johnson D, Letson GD, Zager JS. The role of radical amputations for extremity tumors: a single institution experience and review of the literature. J Surg Oncol. 2012 Feb;105(2):149-155. Pubmedid: 21837679. Pmcid: PMC4504014.
  • Finkelstein SE, Iclozan C, Bui MM, Cotter MJ, Ramakrishnan R, Ahmed J, Noyes DR, Cheong D, Gonzalez RJ, Heysek RV, Berman C, Lenox BC, Janssen W, Zager JS, Sondak VK, Letson GD, Antonia SJ, Gabrilovich DI. Combination of external beam radiotherapy (EBRT) with intratumoral injection of dendritic cells as neo-adjuvant treatment of high-risk soft tissue sarcoma patients. Int J Radiat Oncol Biol Phys. 2012 Feb;82(2):924-932. Pubmedid: 21398051. Pmcid: PMC4241354.
  • Deneve JL, Choi J, Gonzalez RJ, Conley AP, Stewart S, Han D, Werner P, Chaudhry TA, Zager JS. Chemosaturation with percutaneous hepatic perfusion for unresectable isolated hepatic metastases from sarcoma. Cardiovasc Intervent Radiol. 2012 Dec;35(6):1480-1487. Pubmedid: 22699779.
  • Beasley GM, Sharma K, Wong J, Miller M, Turley RS, Lidsky M, Masoud M, Dewhirst MW, Mosca PJ, Zager JS, Tyler DS. A multi-institution experience comparing the clinical and physiologic differences between upper extremity and lower extremity melphalan-based isolated limb infusion. Cancer. 2012 Dec;118(24):6136-6143. Pubmedid: 22674423. Pmcid: PMC5161098.
  • Beasley GM, Parsons C, Broadwater G, Selim MA, Marzban S, Abernethy AP, Salama AK, Eikman EA, Wong T, Zager JS, Tyler DS. A multicenter prospective evaluation of the clinical utility of F-18 FDG-PET/CT in patients with AJCC stage IIIB or IIIC extremity melanoma. Ann Surg. 2012 Aug;256(2):350-356. Pubmedid: 22691370. Pmcid: PMC4618558.
  • Chai CY, Zager JS, Szabunio MM, Marzban SS, Chau A, Rossi RM, Sondak VK. Preoperative ultrasound is not useful for identifying nodal metastasis in melanoma patients undergoing sentinel node biopsy: preoperative ultrasound in clinically node-negative melanoma. Ann Surg Oncol. 2012 Apr;19(4):1100-1106. Pubmedid: 22193886. Pmcid: PMC4504035.
  • Deneve JL, Zager JS. Isolated regional therapy for advanced extremity soft tissue sarcomas. Surg Oncol Clin N Am. 2012 Apr;21(2):287-299. Pubmedid: 22365520.
  • Marcum CB, Zager JS, Bélongie IP, Messina JL, Fenske NA. Profound proliferating angiolymphoid hyperplasia with eosinophilia of pregnancy mimicking angiosarcoma. Cutis. 2011 Sep;88(3):122-128. Pubmedid: 22017064.
  • Han D, Beasley GM, Tyler DS, Zager JS. Minimally invasive intra-arterial regional therapy for metastatic melanoma: isolated limb infusion and percutaneous hepatic perfusion. Expert Opin Drug Metab Toxicol. 2011 Nov;7(11):1383-1394. Pubmedid: 21978383. Pmcid: PMC4630979.
  • Zager JS, Puleo CA, Sondak VK. What is the Significance of the In Transit or Interval Sentinel Node in Melanoma?. Ann Surg Oncol. 2011 Nov;18(12):3232-3234. Pubmedid: 21837524.
  • Zager JS, Rollison DE, Messina J. Prognostication in Merkel cell carcinoma. Expert Rev Anticancer Ther. 2011 May;11(5):665-667. Pubmedid: 21554038.
  • Beasley GM, Riboh JC, Augustine CK, Zager JS, Hochwald SN, Grobmyer SR, Peterson B, Royal R, Ross MI, Tyler DS. Prospective multicenter phase II trial of systemic ADH-1 in combination with melphalan via isolated limb infusion in patients with advanced extremity melanoma. J Clin Oncol. 2011 Mar;29(9):1210-1215. Pubmedid: 21343562. Pmcid: PMC4668281.
  • Mullinax JE, Zager JS, Gonzalez RJ. Current diagnosis and management of retroperitoneal sarcoma. Cancer Control. 2011 Jul;18(3):177-187. Pubmedid: 21666580.
  • Cheong D, Gonzalez RJ, Zager JS. Strategies for solutions in sarcoma management. Cancer Control. 2011 Jul;18(3):148-149. Pubmedid: 21666576.
  • Turaga KK, Beasley GM, Kane JM, Delman KA, Grobmyer SR, Gonzalez RJ, Letson GD, Cheong D, Tyler DS, Zager JS. Limb preservation with isolated limb infusion for locally advanced nonmelanoma cutaneous and soft-tissue malignant neoplasms. Arch Surg. 2011 Jul;146(7):870-875. Pubmedid: 21768436. Pmcid: PMC4515974.
  • Ettinger DS, Agulnik M, Cates JM, Cristea M, Denlinger CS, Eaton KD, Fidias PM, Gierada D, Gockerman JP, Handorf CR, Iyer R, Lenzi R, Phay J, Rashid A, Saltz L, Shulman LN, Smerage JB, Varadhachary GR, Zager JS, Zhen WK. NCCN Clinical Practice Guidelines Occult primary. J Natl Compr Canc Ne. 2011 Dec;9(12):1358-1395. Pubmedid: 22157556.
  • Zager JS, Puleo CA, Sondak VK. Erratum to: What is the Significance of the In Transit or Interval Sentinel Node in Melanoma?. Ann Surg Oncol. 2011 Dec;18 Suppl 3:317-318. Pubmedid: 22048634.
  • Zager JS, Hochwald SN, Marzban SS, Francois R, Law KM, Davis AH, Messina JL, Vincek V, Mitchell C, Church A, Copeland EM, Sondak VK, Grobmyer SR. Shave biopsy is a safe and accurate method for the initial evaluation of melanoma. J Am Coll Surg. 2011 Apr;212(4):454-460. Pubmedid: 21463767. Pmcid: PMC4505798.
  • Santillan AA, Zager JS. Isolated limb infusion for melanoma: a less morbid alternative to hyperthermic isolated limb perfusion in the US. Expert Opin Drug Metab Toxicol. 2010 Sep;6(9):1033-1037. Pubmedid: 20078252.
  • Chu CK, Zager JS, Marzban SS, Gimbel MI, Murray DR, Hestley AC, Messina JL, Sondak VK, Carlson GW, Delman KA. Routine biopsy of Cloquet's node is of limited value in sentinel node positive melanoma patients. J Surg Oncol. 2010 Sep;102(4):315-320. Pubmedid: 20740592.
  • Sondak VK, Zager JS. Who is to blame for false-negative sentinel node biopsies in melanoma?. Ann Surg Oncol. 2010 Mar;17(3):670-673. Pubmedid: 19953329. Pmcid: PMC2820671.
  • Zager JS, Brodsky S, Berman CG. Imaging of Merkel cell carcinoma. Curr Probl Cancer. 2010 Jan;34(1):65-76. Pubmedid: 20371075.
  • Santillan AA, Messina JL, Marzban SS, Crespo G, Sondak VK, Zager JS. Pathology review of thin melanoma and melanoma in situ in a multidisciplinary melanoma clinic: impact on treatment decisions. J Clin Oncol. 2010 Jan;28(3):481-486. Pubmedid: 20008627.
  • Zager JS, Delman KA. Commentary on pharmacotherapy of regional melanoma therapy. Expert Opin Pharmacother. 2010 Jan;11(1):1-3. Pubmedid: 20001424.
  • Sarnaik AA, Zager JS, Cox LE, Ochoa TM, Messina JL, Sondak VK. Routine Omission of Sentinel Lymph Node Biopsy for Merkel Cell Carcinoma <= 1 cm Is Not Justified. J Clin Oncol. 2010 Jan;28(1):e7-e7. Pubmedid: 19933899.
  • Gonzalez RJ, Padhya TA, Cherpelis BS, Prince MD, Aya-Ay ML, Sondak VK, Cruse CW, Zager JS. The surgical management of primary and metastatic Merkel cell carcinoma. Curr Probl Cancer. 2010 Jan;34(1):77-96. Pubmedid: 20371076.
  • Farma JM, Ammori JB, Zager JS, Marzban SS, Bui MM, Bichakjian CK, Johnson TM, Lowe L, Sabel MS, Wong SL, Letson GD, Messina JL, Cimmino VM, Sondak VK. Dermatofibrosarcoma protuberans: how wide should we resect?. Ann Surg Oncol. 2010 Aug;17(8):2112-2118. Pubmedid: 20354798.
  • Feeney K, Maguire HC, McClay EF, Sato T, Sondak VK, Toporcer M, Zager JS. Surgically unresectable regional melanoma metastases in a patient with renal failure and peripheral vascular disease: are there safe and potentially effective treatments?. Semin Oncol. 2010 Aug;37(4):303-313. Pubmedid: 20816500.
  • Santillan AA, Delman KA, Beasley GM, Mosca PJ, Hochwald SN, Grobmyer SR, Andtbacka RH, Noyes RD, Kane JM, Ross MI, Tyler DS, Zager JS. Predictive factors of regional toxicity and serum creatine phosphokinase levels after isolated limb infusion for melanoma: a multi-institutional analysis. Ann Surg Oncol. 2009 Sep;16(9):2570-2578. Pubmedid: 19543771.
  • Beasley GM, Caudle A, Petersen RP, McMahon NS, Padussis J, Mosca PJ, Zager JS, Hochwald SN, Grobmyer SR, Delman KA, Andtbacka RH, Noyes RD, Kane JM, Seigler H, Pruitt SK, Ross MI, Tyler DS. A multi-institutional experience of isolated limb infusion: defining response and toxicity in the US. J Am Coll Surg. 2009 May;208(5):706-715. Pubmedid: 19476821.
  • Möller MG, Pappas-Politis E, Zager JS, Santiago LA, Yu D, Prakash A, Kinal A, Clark GS, Zhu W, Puleo CA, Glass LF, Messina JL, Sondak VK, Cruse CW. Surgical management of melanoma-in-situ using a staged marginal and central excision technique. Ann Surg Oncol. 2009 Jun;16(6):1526-1536. Pubmedid: 19050971.
  • Zager JS, Weber JS. Melanoma: promising new discoveries and treatment modalities for difficult clinical scenarios - part II. Cancer Control. 2009 Jul;16(3):196-197. Pubmedid: 19556959.
  • Phan GQ, Messina JL, Sondak VK, Zager JS. Sentinel lymph node biopsy for melanoma: indications and rationale. Cancer Control. 2009 Jul;16(3):234-239. Pubmedid: 19556963.
  • Sarnaik AA, Puleo CA, Zager JS, Sondak VK. Limiting the morbidity of inguinal lymphadenectomy for metastatic melanoma. Cancer Control. 2009 Jul;16(3):240-247. Pubmedid: 19556964.
  • Zager J, Bui M, Farma J, Messina J, Sondak V. Proper margins of excision in dermatofibrosarcoma protuberans: wide or narrow?. Ann Surg Oncol. 2008 Sep;15(9):2614-2616. Pubmedid: 18452044.
  • Ettinger DS, Agulnik M, Cristea M, Eaton K, Fidias PM, Gockerman JP, Hameed O, Handorf C, Harris EI, Jacobs CD, Javle M, Khushalani NI, Kvols L, Lenzi R, Lewis NL, Rashid A, Saltz L, Shulman LN, Zager JS, Zhen W. Occult primary. J Natl Compr Canc Netw. 2008 Nov;6(10):1026-1060. Pubmedid: 19176200.
  • Moller M, Lewis J, Dessureault S, Zager J. Toxicities associated with hyperthermic isolated limb perfusion and isolated limb infusion in the treatment of melanoma and sarcoma. Int J Hyperthermia. 2008 May;24(3):275-289. Pubmedid: 18393005.
  • Lewis J, Zager J, Yu D, Pelaez D, Riker A, Dessureault S, Cruse C, Reintgen D, Puleo C, Sondak V. Full-thickness grafts procured from skin overlying the sentinel lymph node basin; reconstruction of primary cutaneous malignancy excision defects. Ann Surg Oncol. 2008 Jun;15(6):1733-1740. Pubmedid: 18379848.
  • Zager J, Daud A. Melanoma: promising new discoveries and treatment modalities for difficult clinical scenarios. Cancer Control. 2008 Jul;15(3):192-194. Pubmedid: 18596670.
  • McLoughlin J, Zager J, Sondak V, Berk L. Treatment options for limited or symptomatic metastatic melanoma. Cancer Control. 2008 Jul;15(3):239-247. Pubmedid: 18596676.
  • Gimbel M, Delman K, Zager J. Therapy for unresectable recurrent and in-transit extremity melanoma. Cancer Control. 2008 Jul;15(3):225-232. Pubmedid: 18596674.
  • Melis M, Zager J, Sondak V. Multimodality management of desmoid tumors: how important is a negative surgical margin. J Surg Oncol. 2008 Dec;98(8):594-602. Pubmedid: 19072851.
  • Sarnaik AA, Zager JS, Sondak VK. Multidisciplinary management of special melanoma situations: oligometastatic disease and bulky nodal sites. Curr Oncol Rep. 2007 Sep;9(5):417-427. Pubmedid: 17706171.
  • Gannon C, Zager J, Chang G, Feig B, Wood C, Skibber J, Rodriguez-BigasMA. Pelvic exenteration affords safe and durable treatment for locally advanced rectal carcinoma. Ann Surg Oncol. 2007 Jun;14(6):1870-1877. Pubmedid: 17406945.
  • Sondak V, Zager J, Messina J, Thomas J. Sentinel lymph node biopsy as the standard of care for cutaneous melanoma. Clin Adv Hematol Oncol. 2007 Jun;5(6):483-490. Pubmedid: 17679922.
  • McLoughlin J, Zager J, Sondak V. Cytoreductive surgery for melanoma. Surg Oncol Clin N Am. 2007 Jul;16(3):683-693. Pubmedid: 17606201.
  • Malhotra S, Kim T, Zager J, Bennett J, Ebright M, D'Angelica M, Fong Y. Use of an oncolytic virus secreting GM-CSF as combined oncolytic and immunotherapy for treatment of colorectal and hepatic adenocarcinomas. Surgery. 2007 Apr;141(4):520-529. Pubmedid: 17383529. Pmcid: PMC2559995.
  • Jarnagin W, Zager J, Hezel M, Stanziale S, Adusumilli P, Gonen M, EbrightMI, Culliford A, Gusani N, Fong Y. Treatment of cholangiocarcinoma with oncolytic herpes simplex virus combined with external beam radiation therapy. Cancer Gene Ther. 2006 Mar;13(3):326-334. Pubmedid: 16138120.
  • Lin Y, Deavers M, Sasan F, Zager J, Ramondetta L. Clinical challenges presented by three simultaneous solid tumors. Gynecol Oncol. 2006 Dec;103(3):1159-1163. Pubmedid: 17055558.
  • Kaleya R, Heckman J, Most M, Zager J. Lymphatic mapping and sentinel node biopsy: a surgical perspective. Semin Nucl Med. 2005 Apr;35(2):129-134. Pubmedid: 15765375.
  • Delman K, Zager J, Bhargava A, Petrowsky H, Malhotra S, Ebright M, BennettJJ, Gusani N, Kooby D, Roberts G, Fong Y. Effect of murine liver cell proliferation on herpes viral behavior: implications for oncolytic viral therapy. Hepatology. 2004 Jun;39(6):1525-1532. Pubmedid: 15185293.
  • Bocker J, Vasile J, Zager J, Goodman E. Intussusception: an uncommon cause of postoperative small bowel obstruction after gastric bypass. Obes Surg. 2004 Jan;14(1):116-119. Pubmedid: 14980045.
  • Zager J, Ohki T, Simon J, Gruber B, Zoe H, Teperman S, Stone ME J, VeithFJ, Simon R. Endovascular repair of a traumatic pseudoaneurysm of the thoracic aorta in a patient with concomitant intracranial and intra-abdominal injuries. J Trauma. 2003 Oct;55(4):778-781. Pubmedid: 14566138.
  • Zager J, Delman K, Ebright M, Malhotra S, Larson S, Fong Y. Use of radiolabelled iododeoxyuridine as adjuvant treatment for experimental tumours of the liver. Br J Surg. 2003 Oct;90(10):1225-1231. Pubmedid: 14515291.
  • Jarnagin W, Zager J, Klimstra D, Delman K, Malhotra S, Ebright M, LittleS, DeRubertis B, Stanziale S, Hezel M, Federoff H, Fong Y. Neoadjuvant treatment of hepatic malignancy: an oncolytic herpes simplex virus expressing IL-12 effectively treats the parent tumor and protects againstrecurrence-after resection. Cancer Gene Ther. 2003 Mar;10(3):215-223. Pubmedid: 12637943.
  • Delman KA, Zager JS, Bennett JJ, Malhotra S, Ebright MI, McAuliffe PF, Halterman MW, Federoff HJ, Fong Y. Efficacy of multiagent herpes simplex virus amplicon-mediated immunotherapy as adjuvant treatment for experimental hepatic cancer. Ann Surg. 2002 Sep;236(3):337-342. Pubmedid: 12192320. Pmcid: PMC1422587.
  • Bennett JJ, Delman KA, Burt BM, Mariotti A, Malhotra S, Zager J, Petrowsky H, Mastorides S, Federoff H, Fong Y. Comparison of safety, delivery, and efficacy of two oncolytic herpes viruses (G207 and NV1020) for peritoneal cancer. Cancer Gene Ther. 2002 Nov;9(11):935-945. Pubmedid: 12386832.
  • Ebright M, Zager J, Malhotra S, Delman K, Weigel T, Rusch V, Fong Y. Replication-competent herpes virus NV1020 as direct treatment of pleural cancer in a rat model. J Thorac Cardiovasc Surg. 2002 Jul;124(1):123-129. Pubmedid: 12091817.
  • Stanziale SF, Petrowsky H, Joe JK, Roberts GD, Zager JS, Gusani NJ, Ben-Porat L, Gonen M, Fong Y. Ionizing radiation potentiates the antitumor efficacy of oncolytic herpes simplex virus G207 by upregulating ribonucleotide reductase. Surgery. 2002 Aug;132(2):353-359. Pubmedid: 12219034.
  • Paris F, Grassme H, Cremesti A, Zager J, Fong Y, Haimovitz-Friedman A, Fuks Z, Gulbins E, Kolesnick R. Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes. J Biol Chem. 2001 Mar;276(11):8297-8305. Pubmedid: 11096096.
  • Bennett J, Malhotra S, Wong R, Delman K, Zager J, St-Louis M, Johnson P, Fong Y. Interleukin 12 secretion enhances antitumor efficacy of oncolytic herpes simplex viral therapy for colorectal cancer. Ann Surg. 2001 Jun;233(6):819-826. Pubmedid: 11371740.
  • Zager JS, Delman KA, Malhotra S, Ebright MI, Bennett JJ, Kates T, Halterman M, Federoff H, Fong Y. Combination vascular delivery of herpes simplex oncolytic viruses and amplicon mediated cytokine gene transfer is effective therapy for experimental liver cancer. Mol Med. 2001 Aug;7(8):561-568. Pubmedid: 11591892. Pmcid: PMC1950059.
  • Zager J, Gusani N, Derubertis B, Shaw J, Kaufman J, DeNoto G. Laparoscopic appendectomy for Crohn's disease of the appendix presenting as acute appendicitis. J Laparoendosc Adv Surg Tech A. 2001 Aug;11(4):255-258. Pubmedid: 11569518.
  • Zager J, Shaw J, Kaufman J, DeNoto G. Three cases of small bowel intussusception in relation to a rare lesion: inflammatory fibrous polyps. Dig Surg. 2001;18(2):142-146. Pubmedid: 11351161.
  • Cohen M, Greenwald M, Garbus J, Zager J. Granular cell tumor--a unique neoplasm of the internal anal sphincter: report of a case. Dis Colon Rectum. 2000 Oct;43(10):1444-1446. Pubmedid: 11052524.
  • Jarnagin W, Delman K, Kooby D, Mastorides S, Zager J, Brennan M, BlumgartLH, Federoff H, Fong Y. Neoadjuvant interleukin-12 immunogene therapy protects against cancer recurrence after liver resection in an animal model. Ann Surg. 2000 May;231(5):762-771. Pubmedid: 10767798.
  • Delman KA, Bennett JJ, Zager JS, Burt BM, McAuliffe PF, Petrowsky H, Kooby DA, Hawkins WG, Horsburgh BC, Johnson P, Fong Y. Effects of preexisting immunity on the response to herpes simplex-based oncolytic viral therapy. Hum Gene Ther. 2000 Dec;11(18):2465-2472. Pubmedid: 11119418.
  • Zager J, Garbus J, Shaw J, Cohen M, Garber S. Jejunal diverticulosis: a rare entity with multiple presentations, a series of cases. Dig Surg. 2000;17(6):643-645. Pubmedid: 11155015.
  • McCardle TW, Sondak VK, Zager J, Messina JL. Merkel cell carcinoma: pathologic findings and prognostic factors. Curr Prob Cancer. 34(1):47-64. Pubmedid: 20371074.
  • Khakpour N, Zager J, Yen T, Stephens T, Kuerer H, Singletary E, Ross M, Hunt K, Babiera G. The role of ultrasound in the surgical management of patients diagnosed with ductal carcinoma in situ of the breast. Breast J. 12(3):212-215. Pubmedid: 16684318.