Search Results:
CLINICAL TRIAL 17425
Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk Squamous Cell Cancer of the Head and Neck
Disease Site: Larynx, Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 17431
A Randomized Phase 3 Study of the Efficacy and Safety of Glufosfamide Compared with Fluorouracil (5-FU) in Patients with Metastatic Pancreatic Adenocarcinoma Previously Treated with Gemcitabine
Disease Site: Colon, Liver, Lung, Other Endocrine System, Pancreas, Small Intestine, Stomach
View Trial DetailsCLINICAL TRIAL 17970
A Randomized Phase III Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Observation for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 18610
A Phase I-II Study of Triciribine Phosphate Monohydrate (PTX-200) Plus Cytarabine in Refractory or Relapsed Acute Leukemia
Disease Site: Acute Leukemia (ALL, AML), Acute promyelocytic leukemia (APL), Chronic Leukemia (CLL, CML), Leukemia, other
View Trial DetailsCLINICAL TRIAL 18752
ACTION Trial- Adoptive Cellular Therapy following Dose-Intensified Temozolomide in Newly-diagnosed Pediatric High-grade Gliomas (Phase I)
Disease Site: Brain and Nervous System, Gliomas
View Trial DetailsCLINICAL TRIAL 18959
A Phase 2 Study to Evaluate the Safety, Tolerability and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-145) followed by IL-2 in Patients with Recurrent and/or Metastatic Cervical Carcinoma
Disease Site: Cervix
View Trial DetailsCLINICAL TRIAL 18994
Phase II Randomized Trial of Radiotherapy with or without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) with TP53 Sequencing
Disease Site: Head & Neck, Larynx, Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 19319
InPACT- International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)
Disease Site: Penis / penile cancer, Other Male Genital
View Trial DetailsCLINICAL TRIAL 19414
A Phase 2 Study of Talimogene Laherparepvec (T-VEC) and Radiation in Localized Soft Tissue Sarcoma
Disease Site: Soft Tissue
View Trial DetailsCLINICAL TRIAL 19435
Combination of Nivolumab Immunotherapy with Radiation Therapy and Androgen Deprivation Therapy in the Management of Gleason Group 5 Prostate Cancer
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 19441
Pilot Study of Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 19456
Phase III Randomized Study of Crenolanib versus Midostaurin Administered Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed Subjects with FLT3 Mutated Acute Myeloid Leukemia
Disease Site: Acute Leukemia (ALL, AML), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 19481
Phase I, Open Label Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Expansion, Persistence and Clinical Activity of UCART123 (Allogeneic Engineered T Cells Expressing anti-CD123 Chimeric Antigen Receptor), Administered in Patients with Relapsed/Refractory Acute Myeloid Leukemia
Disease Site: Acute Leukemia (ALL, AML), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 19487
A Phase Ib/II Study to Evaluate the Safety, Feasibility and Efficacy of Nivolumab or Nivolumab in Combination with Azacitidine in Patients with Recurrent, Resectable Osteosarcoma
Disease Site: Any Site, Osteosarcoma
View Trial DetailsCLINICAL TRIAL 19580
A Phase 1/2 Dose Escalation and Dose Expansion Study of BA3011 in Patients with Advanced Solid Tumors
Disease Site: Any Site, Sarcoma
View Trial DetailsCLINICAL TRIAL 19603
Single Arm, Open Label Phase 1b/2 Study of SGN-LIV1A in Combination with Pembrolizumab for First-Line Treatment of Patients with Unresectable Locally-Advanced or Metastatic Triple-Negative Breast Cancer
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 19627
A Randomized Phase III Trial of Consolidation with Autologous Hematopoietic Cell Transplantation Followed by Maintenance Rituximab vs. Maintenance Rituximab Alone for Patients with Mantle Cell Lymphoma In Minimal Residual Disease-Negative First Complete Remission
Disease Site: Lymphoma, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 19635
A Phase 1b/2 Study Evaluating the Safety and Efficacy of Intravenous LB-100 in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) who had Disease Progression or are Intolerant to Prior Therapy
Disease Site: Leukemia, other, Myelodysplastic syndrome (MDS)
View Trial DetailsCLINICAL TRIAL 19646
Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 19658
A Phase 1, Open-Label, Dose-Escalation with Expansion Study of SX-682 in Subjects with Myelodysplastic Syndrome Who Had Disease Progression or are Intolerant to Prior Therapy
Disease Site: Myelodysplastic syndrome (MDS), Leukemia, other
View Trial DetailsCLINICAL TRIAL 19662
Phase II study of stereotactic body radiation therapy and atezolizumab in the management of recurrent, persistent, or metastatic cervical cancer
Disease Site: Cervix
View Trial DetailsCLINICAL TRIAL 19722
A Phase 2, Multi-Cohort, Open-Label, Multicenter Study To Determine The Efficacy And Safety Of Bb2121 In Subjects With Relapsed And Refractory Multiple Myeloma And In Subjects With High-Risk Multiple Myeloma Having Progressed Within One Year Of Initial Treatment
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 19732
Randomized, Double-Blinded Phase III Study of Cabozantinib Versus Placebo in Patients with Advanced Neuroendocrine Tumors after Progression on Everolimus (Cabinet)
Disease Site: Neuroendocrine, Other Endocrine System
View Trial DetailsCLINICAL TRIAL 19742
Phase 1/1b Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemia
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 19776
A Phase 1/2 Dose Escalation and Dose Expansion Study of BA3021 Alone and in Combination with Nivolumab in Patients with Advanced Solid Tumors
Disease Site: Any Site, Bones and Joints, Breast, Esophagus, Larynx, Lung, Other Respiratory and Intrathoracic Organs, Soft Tissue
View Trial DetailsCLINICAL TRIAL 19829
A Phase 1/2a, Open-label, Dose-escalation, Dose-expansion, Parallel Assignment Study to Evaluate the Safety and Clinical Activity of PBCAR0191 in Subjects with Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)
Disease Site: Lymphoid Leukemia, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 19862
A Phase 1/1b Safety Study of PRGN-3006 Adoptive Cellular Therapy in Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndrome
Disease Site: Acute Leukemia (ALL, AML), Myelodysplastic syndrome (MDS), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 19868
First in Human Phase I Study of 225Actinium-DOTA-Ahx-MC1RL (225Ac-MTI-201) in Metastatic Melanoma
Disease Site: Eye and Orbit, Melanoma, skin
View Trial DetailsCLINICAL TRIAL 19870
A Phase 1, Multi-center, Open-label Study of IMGN632 Administered Intravenously in Patients with Relapsed/Refractory CD123-positive Acute Myeloid Leukemia and Other CD123-positive Hematologic Malignancies
Disease Site: Acute Leukemia (ALL, AML), Myeloid and Monocytic Leukemia, Other hematologic
View Trial DetailsCLINICAL TRIAL 19948
A Phase 2 Study of Atezolizumab and Cobimetinib in PD-1/PD-L1 Inhibitor Resistant or Refractory Non-Small Cell Lung Cancer
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 19970
A Pilot Trial of Intratumorally-Administered Topotecan using Convection-Enhanced Delivery (CED) in Patients with Suspected Recurrent/Progressive WHO Grade III or IV (High Grade) Glioma Undergoing Stereotactic Biopsy (IND 117,240)
Disease Site: Brain and Nervous System
View Trial DetailsCLINICAL TRIAL 19989
Targeted Intra-arterial Gemcitabine vs. Continuation of IV Gemcitabine plus Nab-Paclitaxel following Induction with sequential IV Gemcitabine plus Nab-Paclitaxel and Radiotherapy for Locally Advanced Pancreatic Cancer
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 20003-TREATMENT
LungMAP: A Master Protocol to Evaluate Biomarker-Driven Therapies And Immunotherapies In Previously-Treated Non-Small Cell Lung Cancer (Lung-MAP Treatment Substudies)
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 20026
A Phase I Study of NBTXR3 Activated by Radiotherapy for Patients with Advanced Cancers Treated with an Anti-PD1 Therapy
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 20030
A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node or T3N0 Positive Breast Cancer
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 20042
CD8 Depleted, Non-Engrafting, HLA Mismatched Unrelated Donor Lymphocyte Infusion in Patients with MDS and Secondary AML
Disease Site: Acute Leukemia (ALL, AML), Myelodysplastic syndrome (MDS), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20050
QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination with ALT-803 in Patients with BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer
Disease Site: Urinary Bladder
View Trial DetailsCLINICAL TRIAL 20056
Phase II Clinical Trial of Green Tea Catechins in Men on Active Surveillance (AS)
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 20069
A Phase 1, Multi-center, Open-label, Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of an Orally Available Small Molecule CC-99282 Alone and in Combination with Rituximab in Subjects with Relapsed and/or Refractory Diffuse Large B Cell Lymphoma (R/R DLBCL) and Indolent Non-Hodgkin Lymphoma (R/R iNHL)
Disease Site: Lymphoid Leukemia, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 20117
A Phase 1/2 Study of Regn5678 (Anti-psmaxcd28) with Cemiplimab (Anti-pd-1) in Patients with Metastatic Castration-Resistant Prostate Cancer
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 20132
Phase 1/2 Dose-Escalation and Expansion Study of FLX475 Alone and in Combination with Pembrolizumab in Advanced Cancer
Disease Site: Any Site, Breast, Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 20141
A Randomized Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Patients with Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 20144
A Phase 1, First-in-Human, Open-Label, Dose Escalation and Expansion Study of CUE-101 Monotherapy in Second Line and CUE-101 Combination Therapy with Pembrolizumab in First Line Patients with HPV16+ Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)
Disease Site: Head & Neck, Larynx, Lip, Oral Cavity and Pharynx, Squamous Cell Carcinoma (SCC)
View Trial DetailsCLINICAL TRIAL 20149
A Phase 1/2, Open-Label, Multi-Center, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity of TPX-0005 in Patients with Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements (TRIDENT-1)
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 20159
A Phase 1 Study of ZW49 in Patients with Locally Advanced (Unresectable) or Metastatic HER2-Expressing Cancers
Disease Site: Esophagus, Breast
View Trial DetailsCLINICAL TRIAL 20162
Phase 1 Trial of Intralesional Immunotherapy with IFx-Hu2.0 Vaccine in Patients with Advanced Merkel Cell Carcinoma or Cutaneous Squamous Cell Carcinoma
Disease Site: Melanoma, skin, Merkel cell carcinoma, Other Skin, Skin, Squamous Cell Carcinoma (SCC)
View Trial DetailsCLINICAL TRIAL 20163
EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non©\Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNature©\driven Analysis
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 20178
An Open-Label Randomized Phase II Study of Combining Osimertinib with and without Ramucirumab in TKI-naïve EGFR-mutant Locally Advanced or Metastatic NSCLC
Disease Site: Non small cell lung cancer, Lung
View Trial DetailsCLINICAL TRIAL 20251
A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR T cells in subjects with Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma (SPEARHEAD 1 Study)
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 20253
Open Label, Multi-Center, Phase 1b Clinical Trial to Evaluate the Safety and Efficacy of Autologous CAR-BCMA T cells (CT053) in Patients With Relapsed and/or Refractory Multiple Myeloma
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 20270
A Phase 2, Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (LN-144 or LN-145) in Patients with Solid Tumors (IOV-COM-202)
Disease Site: Lung, Melanoma, skin, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 20287
A Phase 1b/2 Study of IMGN632 as Monotherapy or Combination with Venetoclax and/or Azacitidine for Patients with CD123-Positive Acute Myeloid Leukemia
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20305
Phase 1/1b Trial of Donor gamma delta T-cell Infusion for Treatment of Patients with Acute Myeloid Leukemia at High Risk of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
Disease Site: Leukemia, other, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20313
Neoadjuvant Immunotherapy with Intratumoral Tavokinogene Telseplasmid (Tavo) plus Electroporation in Combination with Intravenous Nivolumab in Patients with Operable Locally- Regionally Advanced Melanoma
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 20336
A Phase II Trial of Ribociclib (LEE011) plus Letrozole in Women with Recurrent Low-Grade Serous Carcinoma of the Ovary, Fallopian Tube or Peritoneum
Disease Site: Ovarian, Ovary, Reproductive System
View Trial DetailsCLINICAL TRIAL 20339
Evolutionary Inspired Therapy for Newly Diagnosed, Metastatic, Fusion Positive Rhabdomyosarcoma
Disease Site: Bones and Joints, Rhabdomyosarcoma
View Trial DetailsCLINICAL TRIAL 20345
Phase I/II Trial of Pre-Operative Image Guided Intensity Modulated Proton Radiation Therapy (IMPT) or Photon (IMRT) with Simultaneously Integrated Boost to the High Margin for Retroperitoneal Sarcomas
Disease Site: Anal, Colon, Kidney, Other genitourinary, Pancreas, Rectum, Sarcoma
View Trial DetailsCLINICAL TRIAL 20353
S1806, Phase III Randomized Trial of Concurrent Chemoradiotherapy with or without Atezolizumab in Localized Muscle Invasive Bladder Cancer
Disease Site: Urinary Bladder
View Trial DetailsCLINICAL TRIAL 20373
TH-138: Phase II Randomized Trial of Carboplatin + Pemetrexed + Bevacizumab, With or Without Atezolizumab in Stage IV Non-Squamous NSCLC Patients who Harbor a Sensitizing EGFR Mutation or Have Never Smoked
Disease Site: Non small cell lung cancer, Lung
View Trial DetailsCLINICAL TRIAL 20409
A Phase I/II, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics and Anti-Tumor Efficacy of DZD9008 in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC) with EGFR or HER2 Mutation
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 20415
A Phase III, Open-Label, Multicenter, Randomized Study Evaluating The Safety And Efficacy Of Polatuzumab Vedotin In Combination With RituximabI Plus Gemcitabine Plus Oxaliplatin (R-Gemox) Versus R-Gemox Alone In Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20419
Phase II Study of Short Course FOLFOX Chemotherapy with Either Nivolumab or Nivolumab + Radiation in the First Line Treatment of Metastatic or Unresectable Gastroesophageal Cancers (BMS Protocol CA209-76L)
Disease Site: Esophagus, Other Digestive Organ
View Trial DetailsCLINICAL TRIAL 20484
A Phase 2 Study of Donor-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-401) Administered to Patients with Acute Myeloid Leukemia (AML) following Hematopoietic Stem Cell Transplantation
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20487
Phase I/II Study of Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in the Management of HER2+ Breast Leptomeningeal Disease
Disease Site: Brain and Nervous System, Breast, Leptomeningeal (LMD)
View Trial DetailsCLINICAL TRIAL 20490
Keystroke: A Randomized Phase II Study of Pembrolizumab (Keytruda) Plus Stereotactic Re-irradiation versus SBRT Alone For Locoregionally Recurrent or Second Primary Head and Neck Carcinoma
Disease Site: Other Skin
View Trial DetailsCLINICAL TRIAL 20491
A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase III Trial of Alpha 1 Antitrypsin (AAT) Combined with Corticosteroids vs Corticosteroids Alone for the Treatment of High Risk Acute Graft-versus-Host Disease (GVHD Following Allogeneic Hematopoietic Stem Cell Transplant
Disease Site: Graft vs Host Disease (GVHD), Unknown Sites
View Trial DetailsCLINICAL TRIAL 20494
A Phase II Study of High Dose Bolus IL2 in Combination with Low Dose Ipilimumab Followed Sequentially by Nivolumab in Patients with Inoperable Stage III or Stage IV Melanoma Who Have Failed Prior Anti-PD1 Immunotherapy
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 20497
A Multicenter, Open-Label Phase 1/2 Trial Evaluating the Safety, Tolerability and Efficacy of MORAb-202, a Folate Receptor Alpha (FRA)-Targeting Antibody-Drug Conjugate (ADC) in Subjects with Selected Tumor Types
Disease Site: Ovary
View Trial DetailsCLINICAL TRIAL 20530
Multicenter, Phase II, Neoadjuvant and Adjuvant Study of Alectinib, Entrectinib, or Vemurafenib Plus Cobimetinib in Patients with Stages I-III Non-Small Cell Lung Cancer with ALK, ROS1, NTRK, or BRAF V600E Molecular Alterations
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 20552
A Phase 1b/2 Study Evaluating the Safety and Efficacy of Canakinumab with Darbepoetin alfa in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) who have Failed Erythropoietin Stimulating Agents (ESA)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20578
A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmocodynamics of ALLO-501A, an Anti-CD19 Allogeneic Car T Cell Therapy in Subjects with Relapsed/Refractory Large B-Cell Lymphoma (LBCL)
Disease Site: Lymphoma, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 20608
A Phase 1/2 Study Evaluating the Safety and Efficacy of IOV-2001 in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Disease Site: Chronic Leukemia (CLL, CML), Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 20631
Randomized Prospective Trial of Breast Cancer Locator Guided vs. Wire Localized Partial Mastectomy for Breast Cancer
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 20641
A Randomized Pilot Trial of Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib and Binimetinib in Advanced Melanoma
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 20712
A Phase I Study of Ipilimumab and Nivolumab in Advanced HIV- Associated Solid Tumors, with Expansion Cohorts in HIV-Associated Solid tumors and a Cohort of HIV- Associated Classical Hodgkin Lymphoma
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 20720
S1827, MRI Brain Surveillance Alone Versus MRI Surveillance and Prophylactic Cranial Irradiation (PCI): A Randomized Phase III Trial in Small-Cell Lung Cancer (MAVERICK)
Disease Site: Small cell lung cancer, Lung
View Trial DetailsCLINICAL TRIAL 20722
Phase III Randomized Trial of Pleurectomy/Decortication plus Chemotherapy with or without Adjuvant Hemithoracic Intensity-Modulated Pleural Radiation Therapy (IMPRINT) for Malignant Pleural Mesothelioma (MPM)
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 20731
Phase 2 Study of Afatinib in Advanced Cutaneous Squamous Cell Carcinoma
Disease Site: Other Skin, Squamous Cell Carcinoma (SCC)
View Trial DetailsCLINICAL TRIAL 20733
A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzomab Ozogamicin (a conjugated anti-CD22 monoclonal antibody) to Frontline Therapy in Young Adults (ages 18-39 years) with Newly Diagnosed Precusor B-cell ALL
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20737
Expanded Access Protocol (EAP) for Subjects Receiving Lisocabtagene Maraleucel That is Nonconforming for Commercial Release
Disease Site: Hodgkin's Lymphoma, Lymphoid Leukemia, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 20743
A Multiple-center Phase 2 Study of Acalabrutinib-Lenalidomide-Rituximab in Patients with Previous Untreated Mantle Cell Lymphoma
Disease Site: Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 20749
A Phase 1, Open Label Dose Escalation Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Orally Administered CA-4948 in Patients with Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Disease Site: Leukemia, other, Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20751
A Phase 1/2, Open-Label, Dose-Escalation Trial of GEN3013 in Patients with Relapsed, Progressive or Refractory B-Cell Lymphoma
Disease Site: Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 20752
A Phase 1 Study of Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated Acute Myeloid Leukemia
Disease Site: Leukemia, other, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20760
Open-Label, Multicenter, Phase 1b /2 Clinical Trial to Evaluate the Safety and Efficacy of Autologous Anti-claudin18.2 Chimeric Antigen Receptor T-cell Therapy in Subjects with Advanced Gastric, Pancreatic, or Other Specified Digestive System Cancers
Disease Site: Pancreas, Stomach
View Trial DetailsCLINICAL TRIAL 20767
Integration of Immunotherapy into Adjuvant Therapy For Resected NSCLC: Alchemist Chemo-IO
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 20773
Neoadjuvant Lenvatinib Plus Pembrolizumab in Resectable Merkel Cell Carcinoma
Disease Site: Other Skin, Merkel cell carcinoma
View Trial DetailsCLINICAL TRIAL 20778
Phase 3 Multicenter, Double-Blind, Placebo-Controlled Trial of Viralym M (ALVR-105) for the Treatment of Patients With Virus-Associated Hemorrhagic Cystitis After Allogeneic Hematopoietic Cell Transplant
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 20794
Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma: Safety and Biomarker Analysis
Disease Site: Other Skin, Merkel cell carcinoma
View Trial DetailsCLINICAL TRIAL 20825
A First-in-human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients with Intrahepatic Cholangiocarcinoma (ICC) and Other Advanced Solid Tumors
Disease Site: Other Digestive Organ, Bile Duct Cancer / Cholangiocarcinoma
View Trial DetailsCLINICAL TRIAL 20827
An Open-Label, Multi-Center Phase I/IIa Study Evaluating the Safety and Clinical Activity of Neoantigen Reactive T cells in Patients with Advanced Non-Small Cell Lung Cancer (CHIRON)
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 20832
A Phase II Study to Evaluate the Safety and Efficacy of Prostatic Artery Embolization in Patients with Localized Prostate Carcinoma and Obstructive Lower Urinary Tract Symptoms
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 20837
Envasarc: A Pivitol Trial of Envafolimab, and Envafolimab in Combination with Ipilimumab, in Patients with Advanced or Metastatic Undifferentiated Pleomorphic Sarcoma or Myxofibrosarcoma Who Have Progressed on Prior Chemotherapy
Disease Site: Bones and Joints, Sarcoma
View Trial DetailsCLINICAL TRIAL 20838
A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation, With a Substudy in Subjects With Relapsed or Refractory Myelodysplastic Syndrome and a Substudy in Subjects With Advanced Hematologic Malignancies With Organ Impairment
Disease Site: Leukemia, other, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20848
Phase I/II Study of REGN5668 (MUC16 x CD28, A Costimulatory Bispecific) Administered In Combination With Cemiplimab or REGN4018 (MUC16 x CD3)
Disease Site: Other Female Genital, Ovary
View Trial DetailsCLINICAL TRIAL 20854
Exercise to Boost Response to Checkpoint Blockade Immunotherapy
Disease Site: Melanoma, skin, Other Skin
View Trial DetailsCLINICAL TRIAL 20871
A Phase 3, Open-label, Randomized, Multicenter Study of Ravulizumab in Adult and Adolescent Participants who have Thrombotic Microangiopathy (TMA) after Hematopoietic Stem Cell Transplant (HSCT)
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 20872
An Umbrella Study of INCMGA00012 Alone and in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-Based Chemotherapy (POD1UM-204)
Disease Site: Other Female Genital
View Trial DetailsCLINICAL TRIAL 20873
A Phase 1b, Open-Label Study of Relacorilant in Combination with Pembrolizumab for Patients with Adrenocortical Carcinoma with Excess Glucocorticoid Production
Disease Site: Adrenal, Adrenalcortical cancer
View Trial DetailsCLINICAL TRIAL 20877
A Phase Ib /Randomized Phase III Trial of Patients with Advanced Hematologic Malignancies Undergoing Allogeneic Hematopoietic Cell Transplantation with Either Orca-T, a T-cell-Depleted Graft with Additional Infusion of Conventional T cells and Regulatory T cells, or Standard-of-Care Allogeneic Graft
Disease Site: Leukemia, other, Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20894
Acalabrutinib for Chronic Graft-versus-Host Disease
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 20897
Phase 1 Dose-Escalation, Dose-Expansion Trial of Intratumoral HER2- and HER3-Primed Dendritic Cells Injections for the Treatment of Early-Stage TNBC and ER Low Positive Breast Cancer (DecipHER)
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 20898
A Modular Phase 2a Multicentre Open-Label Study to Investigate DNA-damage Response Agents (or Combinations) in Patients With Advanced Cancer Whose Tumours Contain Molecular Alterations (PLANETTE)
Disease Site: Any Site, Breast, Colorectal, Endometrial/Uterine, Extrapulmonary small cell lung cancer, Gallbladder, Gastric / Stomach, Gastrinoma, Gastrointestinal, Liver, Lung, Non small cell lung cancer, Other genitourinary, Other GI, Pancreas, Prostate, Reproductive System, Urinary Bladder, Uterus
View Trial DetailsCLINICAL TRIAL 20899
Phase I/II Study of Stereotactic Radiation and Abemaciclib in the Management of Hormone Receptor Positive HER2 Negative Breast Cancer Brain Metastases
Disease Site: Brain and Nervous System, Breast
View Trial DetailsCLINICAL TRIAL 20904
A Randomized Phase 2 Trial of Encorafenib + Binimetinib + Nivolumab vs Ipilimumab + Nivolumab in Braf-V600 Mutant Melanoma with Brain Metastases
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 20911
MRI Guided Adaptive Radiation for Locally Advanced Rectal Adenocarcinoma to Enhance Complete Response
Disease Site: Rectum
View Trial DetailsCLINICAL TRIAL 20919
An Open-label, Single-arm, Multicohort, Phase 2 Study to Assess the Efficacy and Safety of Tabelecleucel in Subjects with Epstein-Barr Virus-associated Diseases
Disease Site: Other Hematopoietic
View Trial DetailsCLINICAL TRIAL 20923
A Phase I/II Trial of Maintenance Fedratinib to Prevent Post-Transplant Relapse in Myeloproliferative Neoplasms
Disease Site: Leukemia, other, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20936
DuRvalumab (MEDI4736) with ChEmotherapy as First Line TreAtment in Advanced Pleural Mesothelioma - A Phase 3 Randomised Trial (DREAM3R)
Disease Site: Lung, Mesothelioma
View Trial DetailsCLINICAL TRIAL 20937
A Multicenter, Phase II Trial of Pembrolizumab and Sunitinib In Refractory Advanced Thymic Carcinoma
Disease Site: Other Respiratory and Intrathoracic Organs
View Trial DetailsCLINICAL TRIAL 20938
A Randomized Phase II Trial of Adjuvant Pembrolizumab Versus Observation Following Curative Resection for Stage I Non-Small Cell Lung Cancer (NSCLC) with Primary Tumors Between 1-4 cm
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 20943
Combination of Ipi/Nivo Plus Sacituzumab Govitecan in Metastatic Cisplatin Ineligible Urothelial Carcinoma Patients
Disease Site: Other Urinary, Urinary Bladder, Urothelial Cancer
View Trial DetailsCLINICAL TRIAL 20950
A Phase I/II, Open Label, Multi-center, Non-randomized Dose Escalation and Dose Expansion Study of AMXI-5001 in Patients with Advanced Malignancies
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 20955
A Phase II Study of Binimetinib plus Belinostat for Subjects with Metastatic Uveal Melanoma
Disease Site: Other Skin
View Trial DetailsCLINICAL TRIAL 20963
A Phase 2 Study of Fedratinib in Myelodysplastic /Myeloproliferative Neoplasms (MDS/MPNs) and Chronic Neutrophilic Leukemia (CNL)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20964
A Phase 2 Basket Study of Tucatinib in Combination with Trastuzumab in Subjects with Previously Treated, Locally-Advanced Unresectable or Metastatic Solid Tumors Driven by HER2 Alterations
Disease Site: Brain and Nervous System, Breast, Ill-Defined Sites, Lung, Other Digestive Organ, Urinary Bladder, Brain metastasis, Leptomeningeal (LMD)
View Trial DetailsCLINICAL TRIAL 21023
Open Label, Multicenter Phase II Study of the C5A- Antibody IFX-1 Alone or IFX-1 + Pembrolizumab in Patients with PD-1- or PD-L1-Resistant/Refractory Locally Advanced or Metastatic Cutaneous Squamous Cell Carcinoma (CSCC)
Disease Site: Other Skin
View Trial DetailsCLINICAL TRIAL 21027
A Phase 2 Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (LN-145) in Patients with Metastatic Non-Small-Cell Lung Cancer
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 21035
A Pilot Study of Siltuximab in Large Granular Lymphocytic Leukemia (LGLL)
Disease Site: Lymphoid Leukemia
View Trial DetailsCLINICAL TRIAL 21038
GRECO-2: A Randomized, Phase 2 Study of Stereotactic Body Radiation Therapy (SBRT) in combination with GC4711 in the Treatment of Unresectable or Borderline Resectable, Nonmetastatic Pancreatic Cancer
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 21039
A Pivotal Randomized, Open-Label Study Of OPTUNE(R)(TTFIELDS, 200KHZ) Concomitant With Radiation Therapy And Temozolomide For The Treatment Of Newly Diagnosed Glioblastoma
Disease Site: Brain and Nervous System, Gliomas
View Trial DetailsCLINICAL TRIAL 21046
Phase I Trial with Expansion Cohort of Obp-301 (Telomelysintm) And Definitive Chemoradiation For Patients with Locally Advanced Esophageal And Gastroesophageal Adenocarcinoma Who Are Not Candidates For Surgery
Disease Site: Esophagus
View Trial DetailsCLINICAL TRIAL 21056
A Phase 1b/2, Open-Label, Safety and Efficacy Study of Epcoritamab (GEN3013; DuoBody®-CD3 X CD20) in Relapsed/Refractory Chronic Lymphocytic Leukemia
Disease Site: Lymphoid Leukemia
View Trial DetailsCLINICAL TRIAL 21057
A Randomized, Double-Blind, Phase 3 Study Evaluating the Safety and Efficacy of Venetoclax in Combination with Azacitidine in Patients Newly Diagnosed with Higher-Risk Myelodysplastic Syndrome (Higher-Risk MDS)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21060
A Pilot Study of Ibrutinib and R-da-EPOCH for Front Line Treatment of AIDS-Related Lymphomas
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21074
A Phase 2 Randomized Study of Osimertinib Versus Osimertinib Plus Chemotherapy for Patients with Metastatic EGFR-Mutant Lung Cancers That Have Detectable EGFRMutant cfDNA in Plasma After Initiation of Osimertinib
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 21080
A Phase 1, Open-Label, Dose-Escalation, and Dose-Expansion Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SRK-181 Administered Alone or in Combination with a Checkpoint Inhibitor in Patients with Locally Advanced or Metastatic Solid Tumors (DRAGON)
Disease Site: Any Site, Lung, Melanoma, skin, Urinary Bladder
View Trial DetailsCLINICAL TRIAL 21090
A Study to Evaluate Imetelstat (GRN163L) in Transfusion-Dependent Subjects with IPSS Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) that is Relapsed/Refractory to Erythropoiesis-Stimulating Agent (ESA) Treatment
Disease Site: Myelodysplastic syndrome (MDS), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21094
An Open Label, Multi-Cohort, Multi-Center Phase II Study Evaluating the Efficacy and Safety of IPH4102 Alone or in Combination with Chemotherapy in Patients with Advanced T-cell Lymphoma
Disease Site: Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 21096
A Phase I Study of Duvelisib in Combination with CC-486 in Lymphoid Malignancy
Disease Site: Lymphoid Leukemia, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 21112
Phase 2 Study of Axitinib + Ipilimumab in Advanced Melanoma
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 21113
A Phase I Clinical Trial of an Infusion of Autologous T Cells Genetically Engineered with a Chimeric Receptor to Target the Follicle-Stimulating Hormone Receptor in Patients with Recurrent Ovarian Cancer
Disease Site: Ovary
View Trial DetailsCLINICAL TRIAL 21116
Birinapant and Intensity Modulated Re-Irradiation Therapy (IMRRT) for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC)
Disease Site: Larynx, Lip, Oral Cavity and Pharynx, Head & Neck, Squamous Cell Carcinoma (SCC)
View Trial DetailsCLINICAL TRIAL 21117
A Phase 1 Multicenter Study Evaluating the Safety and Efficacy of ALLO-316 Following ALLO-647 Containing Conditioning Regimen in Subjects with Advanced or Metastatic Clear Cell Renal Cell Carcinoma (ccRCC)
Disease Site: Kidney
View Trial DetailsCLINICAL TRIAL 21119
A Phase 2 Study of VS-6766 (Dual RAF/MEK Inhibitor) Alone and In Combination with Defactinib (FAK Inhibitor) in Recurrent Low-Grade Serous Ovarian Cancer (LGSOC)
Disease Site: Ovary
View Trial DetailsCLINICAL TRIAL 21122
A Multicenter, Phase 1, Open-label, Dose-escalation and Expansion Study of TNB-486, a Bispecific Antibody Targeting CD19 in Subjects with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Disease Site: Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 21126
A Phase 1 Open-label, Multicenter Study Evaluating the Safety of KITE-222, an Autologous Anti-CLL-1 CAR T-cell Therapy, in Subjects with Relapsed/Refractory Acute Myeloid Leukemia
Disease Site: Leukemia, other
View Trial DetailsCLINICAL TRIAL 21129
A Phase 1/1b, Open-Label, Multicenter, Dose-Escalation Study of RMC-5552 Monotherapy in Adult Subjects with Relapsed/Refractory Solid Tumors
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21131
A Phase II Randomized Trial of Adjuvant Therapy with Pembrolizumab After Resection of Recurrent/Second Primary Head and Neck Squamous Cell Carcinoma with High Risk Features
Disease Site: Larynx, Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 21135
Randomized, Placebo-Controlled, Phase II Trial Examining Ustekinumab for Prevention of Graft vs. Host Disease after Allogeneic Hematopoietic Cell Transplantation
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21136
Phase 2 Clinical Trial of Radiomic Habitat-Directed Radiation Dose Escalation for High-Grade Soft Tissue Sarcoma
Disease Site: Soft Tissue
View Trial DetailsCLINICAL TRIAL 21139
A Phase IIA Study of Sequential ("first strike, second strike") Therapies, Modeled on Evolutionary Dynamics of Anthropocene Extinctions, for High Risk Metastatic Castration Sensitive Prostate Cancer
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 21140
Phase I Trial With Expansion Cohort Of DNA-PK Inhibition And IMRT In Cisplatin-Ineligible Patients With Stage 3-4 Local-Regionally Advanced Head And Neck Squamous Cell Carcinoma (HNSCC)
Disease Site: Larynx, Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 21142
A Phase 1b, Multicenter, Open-label Platform Study of Select Drug Combinations in Adult Patients with Lower Risk (Very Low, Low, or Intermediate Risk) Myelodysplastic Syndrome (CMBG453E12101)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21157
A Phase I/Ib Open-Label, Multi-Center, Dose-Escalation Study To Investigate The Safety, Pharmacokinetics And Preliminary Efficacy Of Intravenous NBF-006 In Patients With Non-Small Cell Lung, Pancreatic, Or Colorectal Cancer Followed By A Dose Expansion Study In Patients With KRAS-Mutated Non-Small Cell Lung Cancer
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 21163
A Phase 1/2 Study of Regn7075 (Egfrxcd28 Costimulatory Bispecific Antibody) in Combination with Cemiplimab in Patients with Advanced Solid Tumors
Disease Site: Anus, Breast, Cervix, Colon, Esophagus, Kidney, Lip, Oral Cavity and Pharynx, Lung, Other Digestive Organ, Other Female Genital, Other Male Genital, Other Skin, Other Urinary, Pancreas, Prostate, Stomach
View Trial DetailsCLINICAL TRIAL 21167
A Phase 1/2 Open-label Study Investigating the Safety, Tolerability and Efficacy of ASP7517 in Subjects with Relapsed/Refractory Acute Myeloid Leukemia (AML) and Relapsed/Refractory Higher Risk Myelodysplastic Syndrome (MDS)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21180
A First-in-Human, Two-Part, Open-Label, Clinical Study to Assess the Safety, Tolerability and Activity of Intravenous Doses of ICT01 as Monotherapy and in Combination with an Immune Checkpoint Inhibitor, in Patients with Advanced-Stage, Relapsed/Refractory Cancer (EVICTION Study)
Disease Site: Any Site, Breast, Colon, Larynx, Leukemia, other, Lip, Oral Cavity and Pharynx, Lung, Melanoma, skin, Ovary, Prostate, Stomach, Urinary Bladder
View Trial DetailsCLINICAL TRIAL 21186
ACCESS: A Multi-Center, Phase II Trial of HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide for Patients with Hematologic Malignancies
Disease Site: Leukemia, other, Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21192
A Phase 2 Study of the Combination Dostarlimab with Niraparib In Patients with Penile Carcinoma Who Have Progressed Following Chemotherapy
Disease Site: Other Male Genital
View Trial DetailsCLINICAL TRIAL 21209
A Phase 1, Open Label, Multiple-Ascending Dose Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, And Preliminary Efficacy of KD033 In Subjects With Metastatic Or Locally Advanced Solid Tumors
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21213
A Single-Arm, Open-Label Phase 1b Study of Hyper-CVAD + Calaspargase pegol in Young Adults with Newly Diagnosed Acute Lymphoblastic Leukemia
Disease Site: Lymphoid Leukemia
View Trial DetailsCLINICAL TRIAL 21222
Older Non-Small Cell Lung Cancer Patients (>/= 70 Years of Age) Treated With First-Line Mk-3475 (Pembrolizumab) +/- Chemotherapy (Oncologist s/Patient s Choice) A171901
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 21227
A Randomized Phase II Study of Gemcitabine and Nab-Paclitaxel Compared with 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan in Older Patients with Treatment Naïve Metastatic Pancreatic Cancer (GIANT)
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 21228
A Phase 1/2 Open-Label, Dose-Escalation and Clinical Response Study of Quaratusugene Ozeplasmid in Combination with Pembrolizumab versus Docetaxel with or without Ramucirumab in Patients with Previously Treated Non-Small Cell Lung Cancer (Acclaim 2)
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 21239
Randomized Phase II/III Study of Nivolumab plus Ipilimumab plus Sargramostim versus Nivolumab plus Ipilimumab in Patients with Unresectable Stage III or Stage IV Melanoma
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 21248
A Phase 3, Randomized, Open-Label Study Evaluating the Safety and Efficacy of Magrolimab in Combination with Azacitidine versus Physician s Choice of Venetoclax in Combination with Azacitidine or Intensive Chemotherapy in Previously Untreated Patients with TP53 Mutant Acute Myeloid Leukemia
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21249
A Phase 2, Open-Label, Multi-Center Study of Venetoclax in Combination with Carfilzomib and Dexamethasone in Subjects with Relapsed or Refractory Multiple Myeloma
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 21257
A Phase 1 First-in-Human Study with ABBV-155 Alone and in Combination with Taxane Therapy in Adults with Relapsed and/or Refractory Solid Tumors
Disease Site: Breast, Lung
View Trial DetailsCLINICAL TRIAL 21273
A Randomized, Pilot Study to Evaluate the Molecular and Cellular Response to Treatment with Nivolumab with either Adjuvant Ipilimumab or Relatlimab in Adult Patients with Surgically Resectable Melanoma Brain Metastases
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 21336
A Phase I/Ib Global, Multicenter, Open-Label Umbrella Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients with Metastatic Colorectal Cancer (Intrinsic)
Disease Site: Colon
View Trial DetailsCLINICAL TRIAL 21344
A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients with Melanoma (Morpheus-Melanoma)
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 21366
Administration of HIV-specific T Cells to HIV+ Patients Receiving High Dose Chemotherapy Followed by Autologous Stem Cell Rescue -Auto-RESIST
Disease Site: Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 21372
A Phase 1a/1b Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PY314 as a Single Agent and In Combination with Pembrolizumab in Subjects with Advanced Solid Tumors
Disease Site: Ill-Defined Sites
View Trial DetailsCLINICAL TRIAL 21378
Phase 1 Study of Adoptive T Cell Therapy Following HER2-Pulsed Dendritic Cell Vaccine and Pepinemab / Trastuzumab in Patients with Metastatic HER2-Positive Breast Cancer
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21381
A Phase 1b Dose Escalation Study of BOLD-100 in Combination with FOLFOX Chemotherapy in Patients with Advanced Solid Tumours
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 21383
A Prospective, Randomized, Controlled, Open-label, Multicenter Trial to Evaluate Efficacy, Safety and Patient-reported Outcomes of Peptide Receptor Radionuclide Therapy (PRRT) with Lutetium (177Lu) Edotreotide compared to Best Standard of Care in Patients with Well-differentiated Aggressive Grade 2 and Grade 3, Somatostatin Receptor-positive (SSTR+), Neuroendocrine Tumors of GastroEnteric or Pancreatic Origin (COMPOSE)
Disease Site: Other Digestive Organ, Other Endocrine System
View Trial DetailsCLINICAL TRIAL 21399
Phase I Study of MEM-288 Oncolytic Virus in Solid Tumors Including Non-Small Cell Lung Cancer (NSCLC)
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 21405
Phase 2, Single Arm Study of Luspatercept for the Treatment of Anemia in lower Risk Myelodysplastic Syndromes (MDS) or Non-proliferative Myelodysplastic Syndromes/Myeloproliferative Neoplasms (MDS/MPN)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21410
A Phase 1 Study of ZN-c3 as a Single Agent in Subjects with Solid Tumors
Disease Site: Ovary
View Trial DetailsCLINICAL TRIAL 21412
A Phase 3 Double-Blind, Randomized, Placebo Controlled Study to Evaluate the Efficacy and Safety of AB-205 plus Standard of Care versus Placebo plus Standard of Care in Adults with Lymphoma Undergoing High-Dose Therapy and Autologous Hematopoietic Cell Transplantation (HDT-AHCT) (E-CELERATE)
Disease Site: Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 21421
A Phase 3 (Pivotal Stage) Study of NBTXR3 Activated by Investigators Choice of Radiotherapy Alone or Radiotherapy in Combination with Cetuximab for Platinum-based Chemotherapy-ineligible Elderly Patients with Locally Advanced Head & Neck Squamous Cell Carcinoma
Disease Site: Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 21433
A Phase 1 and 2a open-label trial to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and antitumor activity of LAVA-1207, a PSMA-targeting bispecific γδ-T cell engager, in patients with therapy refractory metastatic castration resistant prostate cancer
Disease Site: Other
View Trial DetailsCLINICAL TRIAL 21450
A Phase 1/1b Dose Escalation and Expansion of CPX-351 in Combination with Gemtuzumab Ozogamicin in Newly Diagnosed Acute Myeloid Leukemia
Disease Site: Myeloid and Monocytic Leukemia, Acute Leukemia (ALL, AML)
View Trial DetailsCLINICAL TRIAL 21459
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)
Disease Site: Colon
View Trial DetailsCLINICAL TRIAL 21460
Phase Ib Trial of Erdafitinib Combined with Enfortumab Vedotin Following Platinum and PD1/L1 Inhibitors for Metastatic Urothelial Carcinoma with FGFR2/3 Genetic Alterations
Disease Site: Other Urinary
View Trial DetailsCLINICAL TRIAL 21513
A Phase 1 Study of KZR-261, a Small Molecule Sec61 Inhibitor, in Subjects with Advanced Solid Malignancies
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21518
A Phase 1/1b Open-Label, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of KIN-2787 in Participants with BRAF and/or NRAS Mutation Positive Solid Tumors
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21534
Randomized Phase III Trial of MEDI4736 (Durvalumab) as Concurrent and Consolidative Therapy or Consolidative Therapy Alone for Unresectable Stage 3 NSCLC
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 21550
A Phase 1, Multi-center, Open-label, Dose Finding Study of CC-92328 in Subjects with Relapsed and/or Refractory Multiple Myeloma
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 21553
A Multicenter, Randomized, Double-Blind Phase 3 Study of HBI-8000 Combined with Nivolumab versus Placebo with Nivolumab in Patients with Unresectable or Metastatic Melanoma Not Previously Treated with PD-1 or PD-L1 Inhibitors
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 21573
An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients with Hepatic Dominant Ocular Melanoma
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 21580
A Phase 1 Study of PBCAR19B in Subjects with CD19-expressing Malignancies
Disease Site: Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 21587
A Dose-escalation Study of the Safety and Pharmacology of DAN 222 in Subjects with Metastatic Breast Cancer
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21606
Phase 1/2, Double-Blind, Placebo-Controlled, Dose Escalation and Expansion Study of ALVR106 in Addition to Standard of Care for the Treatment of High-Risk Patients with Respiratory Viral Infections After Hematopoietic Cell Transplant
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21609
A Phase I Dose Escalation And Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, And Anti-Tumor Activity Of PF-07260437 In Advanced Or Metastatic Solid Tumors
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21622
A Phase 1/1b Dose Escalation/Dose Expansion Study of PRGN-3007 UltraCAR-T Cells in Patients with Advanced Hematologic and Solid Tumor Malignancies
Disease Site: Breast, Hodgkin's Lymphoma, Leukemia, other
View Trial DetailsCLINICAL TRIAL 21623
A Phase 1/2 Study of bbT369, a Dual Targeting CAR T cell Drug Product with a Gene Edit, in Relapsed and/or Refractory B cell Non-Hodgkin s Lymphoma
Disease Site: Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 21636
A Dose-Escalation and Expansion Study of the Safety and Efficacy of XL092 in Combination with Immuno-Oncology Agents in Subjects with Unresectable Advanced or Metastatic Solid Tumors
Disease Site: Breast, Colon, Prostate, Urinary Bladder
View Trial DetailsCLINICAL TRIAL 21641
First-in-Human, Phase 1/1b, Open-label, Multicenter Study of Bifunctional EGFR/TGF_ Fusion Protein BCA101 Alone and in Combination with Pembrolizumab in Patients With EGFR-Driven Advanced Solid Tumors
Disease Site: Larynx, Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 21652
An Open-label, Multicenter, Phase 2 Study of Sacituzumab Govitecan Combinations in First-line Treatment of Patients with Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC) Without Actionable Genomic Alterations
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 21657
Randomized Phase II/III Trial of Radiation with High-Dose Cisplatin (100 mg/m2) Every Three Weeks Versus Radiation with Low-Dose Weekly Cisplatin (40 mg/m2) for Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Disease Site: Larynx, Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 21664
Phase 1b/3 z=Global, Randomized, Controlled, Open-Label Trial Comparing Treatment with RYZ101 to Standard of Care (SoC) Therapy in Subjects with Inoperable, Advanced, Somatostatin Receptor Expressing (SSTR+), Well-Differentiated Gastro-Enteropancreatic Neuroendocrine Tumors (GEP-NETs) that have Progressed Following Prior 177Lulabelled Somatostatin Analogue (177Lu-SSA) Therapy (ACTION-1).
Disease Site: Esophagus, Other Digestive Organ, Pancreas, Small Intestine, Stomach
View Trial DetailsCLINICAL TRIAL 21665
Randomized Phase II Trial of Postoperative Adjuvant Capecitabine And Temozolomide Versus Observation in High-Risk Pancreatic Neuroendocrine Tumors
Disease Site: Other Digestive Organ, Pancreas
View Trial DetailsCLINICAL TRIAL 21666
A Phase I Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of TST001 in Patients with Locally Advanced or Metastatic Solid Tumors
Disease Site: Other Digestive Organ
View Trial DetailsCLINICAL TRIAL 21673
A Randomized, Multicenter, Placebo-controlled, Phase 3 study to Evaluate the Efficacy and Safety ofHER2/neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/neu Positive Subjects with Residual Disease or High-Risk PCR after both Neoadjuvant and Postoperative Adjuvant Trastuzumab-based Therapy(FLAMINGO-01)
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21691
A Multi-center, Double-Blind, Randomized Phase 3 Study to Compare the Efficacy and Safety of Belzutifan (MK-6482) plus Pembrolizumab (MK- 3475) Versus Placebo plus Pembrolizumab, in the Adjuvant Treatment of Clear Cell Renal Cell Carcinoma (ccRCC) Post Nephrectomy (6482-022)
Disease Site: Kidney
View Trial DetailsCLINICAL TRIAL 21696
A Phase 1/2 Dose-Escalation and Dose-Expansion of the Safety and Efficacy of Anti-CD7 Allogeneic CAR-T cells (WU-CART-007) in Patients with Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia /Lymphoblastic Lymphoma (T-ALL)/Lymphoblastic Lymphoma (LBL)
Disease Site: Lymphoid Leukemia, Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 21698
A Phase 2, Multicenter, Open-Label Study of Lurbinectedin Efficacy and Safety in Participants with Advanced or Metastatic Solid Tumors
Disease Site: Ill-Defined Sites, Lung, Urinary Bladder
View Trial DetailsCLINICAL TRIAL 21701
A Phase 1/1b Dose Escalation/Expansion Study of NGM831 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumors
Disease Site: Any Site, Breast, Cervix, Esophagus, Kidney, Larynx, Lip, Oral Cavity and Pharynx, Liver, Lung, Other Digestive Organ, Ovary
View Trial DetailsCLINICAL TRIAL 21707
A Proof of Concept Study of TBio-4101 (an autologous selected and expanded tumor infiltrating lymphocyte [TIL] therapy) using Short-Term Cultured, Selected Autologous TIL Following a Lymphodepleting Chemotherapy Regimen and Followed by IL-2 for Patients with Relapsed or Refractory Melanoma (Phase 1)
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 21712
A Phase 2 Open Label Study to Evaluate the Safety and Effectiveness of 212Pb-DOTAMTATE in PRRT Naïve Subjects with Somatostatin Receptor Expressing Neuroendocrine Tumors
Disease Site: Any Site, Liver, Lung, Other Digestive Organ, Other Endocrine System, Pancreas, Rectum, Small Intestine, Stomach
View Trial DetailsCLINICAL TRIAL 21728
A Phase I/II Study of TTI-621 in Combination with Doxorubicin in Patients with Unresectable or Metastatic High-Grade Leiomyosarcoma
Disease Site: Soft Tissue
View Trial DetailsCLINICAL TRIAL 21731
A Phase II Trial of Olaparib in Combination with Pembrolizumab for Advanced Uveal Melanoma
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 21741
A Phase 1 Study of AGEN2373, an Anti-CD137 Monoclonal Antibody, as Monotherapy and in Combination with AGEN1181, an Fc-Enqineered Anti-CTLA-4 Monoclonal Antibody, in Patients with Advanced Cancer
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21756
A Phase 3 Study of the Hepcidin Mimetic Rusfertide (PTG-300) in Patients with Polycythemia Vera
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21757
Phase II Study of Genomically Guided Radiation Dose Personalization in the Management of Triple Negative Breast Cancer
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21761
A Phase 1 First-in-Human Dose-escalation and Dose-expansion Study of BMF-219, an Oral Irreversible Menin Inhibitor, in Adult Patients with Acute Leukemia Including Those with an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Disease Site: Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21778
An Open-Label Phase 1A/1B Dose Escalation and Expansion Cohort Study of SL-172154 (SIRPα-Fc-CD40L) in Combination With Azacitidine or With Azacitidine and Venetoclax for the Treatment of Subjects With Higher-Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML)
Disease Site: Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21850
Phase 1/1b, Multicenter, Open-Label, Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects with Advanced KRASG12C Mutant Solid Tumors
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 21870
A Phase 2 trial of Nirogacestat in Patients with Recurrent Ovarian Granulosa Cell Tumors
Disease Site: Ovary
View Trial DetailsCLINICAL TRIAL 21879
Phase 1 Study of the PKMYT1 Inhibitor RP-6306 in Combination With FOLFIRI for the Treatment of Advanced Solid Tumors (MINOTAUR Study)
Disease Site: Esophagus, Other Digestive Organ
View Trial DetailsCLINICAL TRIAL 21880
Risk-Adapted Therapy of HIV-Associated Anal Cancer
Disease Site: Anus
View Trial DetailsCLINICAL TRIAL 21892
A Phase 2, Single-Arm, Open-Label Study using Itacitinib as Pre-Modulation in Patients with Diffuse Large B-Cell Lymphoma (DLBCL) Receiving CAR-T-Cell Therapy
Disease Site: Non-Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 21894
Phase 1 Clinical Trial of lntravesical Adoptive Cell Therapy {ACT) with Tumor Infiltrating Lymphocytes (TIL) for Patients with BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer {NMIBC)
Disease Site: Urinary Bladder
View Trial DetailsCLINICAL TRIAL 21899
Phase Ib Expansion Study of CX-5461 in Patients with Solid Tumours and BRCA2 and/or PALB2 Mutation
Disease Site: Breast, Other Female Genital, Ovary, Pancreas, Prostate
View Trial DetailsCLINICAL TRIAL 21901
Phase 1 Study of the PKMYT1 Inhibitor RP-6306 in Combination with Gemcitabine for the Treatment of Advanced Solid Tumors (MAGNETIC Study)
Disease Site: Ovary
View Trial DetailsCLINICAL TRIAL 21913
A Phase 3 Study of CG0070 In Patients with Non- Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus Calmette-Guerin (BCG)
Disease Site: Urinary Bladder
View Trial DetailsCLINICAL TRIAL 21937
A Prospective, Multi-Center, Randomized, Double-Arm Trial to Determine the Impact of the SELENE System on Positive Margin Rates in Breast Conservation Surgery
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21945
Phase 2, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Topically Administered LUT014 in Metastatic Colorectal Cancer Patients with EGFR Inhibitor Induced Acneiform Lesions Protocol
Disease Site: Colon
View Trial DetailsCLINICAL TRIAL 21964
Phase 2, Multicenter, Open-Label Basket Study of Navicixizumab Monotherapy or in Combination with Paclitaxel or Irinotecan in Patients with Select Advanced Solid Tumors
Disease Site: Other Digestive Organ
View Trial DetailsCLINICAL TRIAL 21971
Phase I Clinical Trial of CD40L-augmented Tumor Infiltrating Lymphocytes (CD40L TIL) for Patients with Oncogene-Driven Advanced Non-Small Cell Lung Cancer (NSCLC)
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 21989
Pivotal Study of the NanoKnife System for Ablation of Prostate Tissue in an Intermediate-Risk Patient Population
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 21997
Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma
Disease Site: Other Skin
View Trial DetailsCLINICAL TRIAL 22003
A Phase II Randomized Study of Sipuleucel-T with or without Continuing New Hormonal Agents (NHA) in Metastatic Prostate Cancer with PSA Progression while on NHA and LHRH Analog
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 22068
A Phase 1 Study of the SHP2 Inhibitor BBP-398 (formerly known as IACS-15509) in Combination with the Programmed Death Receptor-1 Blocking Antibody Nivolumab in Patients with Advanced Non-Small Cell Lung Cancer with a KRAS Mutation
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 22071
Melanoma Margins Trial (MelMarT): A Phase III, multi-centre, multi-national randomised control trial investigating 1cm v 2cm wide excision margins for primary cutaneous melanoma
Disease Site: Other
View Trial DetailsCLINICAL TRIAL 22102
A Phase 1b, First-in-human, Dose Escalation and Expansion, Multicenter Study of XMT-1660 in Participants with Solid Tumors
Disease Site: Breast, Other Female Genital, Ovary
View Trial DetailsCLINICAL TRIAL 22112
A Phase 1, Open-Label, Dose Escalation and Expansion Study of CUE-102 Monotherapy in HLA-A*0201 Positive Patients with WTl Positive Recurrent/Metastatic Cancers
Disease Site: Esophagus, Other Digestive Organ
View Trial DetailsCLINICAL TRIAL 22449
Expanded Access Program for belantamab mafodotin in Patients with Relapsed/Refractory Multiple Myeloma who are Refractory to a Proteasome Inhibitor, and an Immunomodulatory Agent, and an Anti-CD38 Antibody
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 90001
A Phase 2, Multicenter, Single-Arm Study of Retreatment with Brentuximab Vedotin in Subjects with Relapsed or Refractory Classic Hodgkin lymphoma (cHL) or CD30-Expressing Peripheral T Cell Lymphoma (PTCL)
Disease Site: Hodgkin's Lymphoma
View Trial DetailsCLINICAL TRIAL 90005
Phase Ib First in Human Dose Escalation of GT103 in Refractory, Advanced Stage Non-Small Cell Lung Cancer
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 90009
A Multicentre, Open-label, Non-randomised First in Human Study of NG-641, an Oncolytic Transgene Expressing Adenoviral Vector, in Patients With Metastatic or Advanced Epithelial Tumours (STAR)
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 90016
A Phase 1b Open-Label Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination with Other Anti-cancer Agents in Patients with Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)
Disease Site: Other Hematopoietic
View Trial DetailsCLINICAL TRIAL 90035
A Phase Ib, Open-Label, Multicenter, Single Arm Study Evaluating The Preliminary Efficacy, Safety, And Pharmacokinetics Of Glofitamab In Combination With Rituximab Plus Ifosfamide, Carboplatin Etoposide Phosphate In Patients With Relapsed/Refractory Transplant Eligible Diffuse B-Cell Lymphoma
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 22177
Intermediate-Size Population Expanded Access Program (EAP) for Ciltacabtagene Autoleucel (cilta-cel) Out-of-Specification (OOS) in Patients with Multiple Myeloma
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 19731
Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator Intervention for Neuro-Oncology Couples
Disease Site: Brain and Nervous System, Brain metastasis, Gliomas, Leptomeningeal (LMD), Meningiomas
View Trial DetailsCLINICAL TRIAL 20413
Phase III Study Of Daratumumab/Rhuph20 (Nsc- 810307) + Lenalidomide Or Lenalidomide As Post-Autologous Stem Cell Transplant Maintenance Therapy In Patients With Multiple Myeloma (MM) Using Minimal Residual Disease To Direct Therapy Duration (DRAMMATIC STUDY)
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 20479
Efficacy of SOAR (Survivors Overcoming and Achieving Resiliency) Survivorship Workshop for Breast Cancer Survivors
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 20551
Bright IDEAS-Young Adults: Problem-Solving Skills Training to Reduce Distress Among Young Adults with Cancer
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 20561
Randomized Trial of Prolonged Use of Negative Pressure Wound Therapy in Patients Undergoing Surgical Procedures for the Management of Gastrointestinal Malignancies
Disease Site: Other Digestive Organ
View Trial DetailsCLINICAL TRIAL 21742
Tele-Resistance Training During Chemotherapy For Advanced Upper Gastrointestinal Cancer
Disease Site: Esophagus, Small Intestine, Stomach
View Trial DetailsCLINICAL TRIAL 21795
Early Supportive Care and Nutritional Support in Adults with Pancreatic Cancer.
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 21889
Support Through Remote Observation and Nutrition Guidance (STRONG) Program for Gastroesophageal Cancer (GEC) Patients
Disease Site: Esophagus
View Trial DetailsCLINICAL TRIAL 22082
Support Through Remote Observation and Nutrition Guidance (STRONG) Program for Pancreatic Cancer Patients
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 22110
AutoFOCUS: A Mindfulness-Based Intervention for Autologous HCT Cancer Caregivers
Disease Site: Other Hematopoietic
View Trial DetailsCLINICAL TRIAL 22115
Feasibility Of Exercise Prehabilitation Among Older Patients With Hematological Malignancies Preparing For Chimeric Antigen Receptor (CAR) T-Cell Immunotherapy
Disease Site: Leukemia, other, Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 22117
STRONG-PD: Support Through Remote Observation And Nutrition Guidance (STRONG) Program For Cancer Patients With Peritoneal Disease
Disease Site: Colon, Other Digestive Organ
View Trial DetailsCLINICAL TRIAL 22330
The ENHANCE Study: Exercise and Nutrition in Head And Neck CancEr Survivors: A Randomized Clinical Trial
Disease Site: Larynx, Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 19305
CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease
Disease Site: Other hematologic, Unknown Sites, Leukemia, other
View Trial DetailsCLINICAL TRIAL 19622
Phase II Trial of Investigational Agents to Modulate Intermediate Endpoint Biomarkers, Including Pulmonary Nodules, in Former and Current Smokers
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 20154
Partnering with a State Food Bank to Provide Tobacco Treatment to Underserved Smokers
Disease Site: Other
View Trial DetailsCLINICAL TRIAL 20337
Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living with HIV
Disease Site: Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 21224
Determining the Structural- and Functional-Level Effects of Diet-specific Interventions on The Gut Microbiota of a Diverse Sample of Southern United States Adults
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21236
Improving Weight Loss Outcomes of Black Women Using a Culturally-Relevant Stress-Management Enhanced Behavioral Weight Loss Intervention
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21426
Phase 2/3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Posoleucel (ALVR105, Viralym-M) Compared to Placebo for the Prevention of AdV, BKV, CMV, EBV, HHV-6, and JCV Infection and/or Disease, in High-Risk Patients After Allogeneic Hematopoietic Cell Transplant
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21885
Enhancing Long-Term Smoking Abstinence Among Cervical Cancer Survivors (Project ACCESS)
Disease Site: Cervix
View Trial DetailsCLINICAL TRIAL 21902
HPV Multilevel Intervention Strategies Targeting Immunization in Community Settings (HPV MISTICS)
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21940
M4OC-Prevent 2.0: Phase IIb Trial of Metformin for Oral Cancer Prevention
Disease Site: Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 19291
The Utility of PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men with High GC Decipher® Test Scores: A Sub-aim of the VANDAAM Study (MCC #18523)
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 19974
Contrast-Enhanced Ultrasound for the Evaluation of Changes in Tumor Blood Flow and the Surrounding Hepatic Parenchyma before, during and after Hepatic Artery Embolization
Disease Site: Liver
View Trial DetailsCLINICAL TRIAL 20786
Efficacy Of A Mindfulness-Based Stress Management Program For Allogeneic HCT Caregivers
Disease Site: Other Hematopoietic
View Trial DetailsCLINICAL TRIAL 21235
Clinical Trials Outreach & Education
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21767
Phase 2: Using Biomarkers for Diagnosis, Risk Stratification of Post-Treatment Recurrence and Long-Term Surveillance of Lung Cancer
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 22152
Comparative effectiveness of Juntos Después del Cáncer (JDC) among Breast Cancer Survivors and their Intimate Partners
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21355
Prospective Cohort Study Of The Immune Response To Severe Acute Respiratory Coronavirus 2 (SARS-Cov2) In Oncology Workers: Protect Covid-19 Study
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 14690
Total Cancer Care Protocol: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 15768
Total Lung Care (TLC): Epidemiology of Lung Cancer
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 16028
Transdisciplinary Research in Colorectal Cancer: The ColoCare Study
Disease Site: Colorectal, Colon, Rectum
View Trial DetailsCLINICAL TRIAL 16933
Older Breast Cancer Patients: Risk For Cognitive Decline
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 17716
A Biomarker-related Approach to Screening for HPV-related Oropharyngeal Cancer
Disease Site: Larynx, Throat, Lip, Oral Cavity and Pharynx
View Trial DetailsCLINICAL TRIAL 17723
Expansion of Enduring Infrastructure to Support Lung Cancer Screening Research
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 18926
The National Myelodysplastic Syndromes (MDS) Study
Disease Site: Leukemia, other, Lymphoid Leukemia, Multiple Myeloma, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 19209
Combined Imaging and Blood Biomarkers for Breast Cancer Diagnosis
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 19943
Somatostatin receptor expression in poorly-differentiated neuroendocrine carcinomas of the GI tract: analysis using 68Ga-dotatate PET scan
Disease Site: Pancreas, Gastrointestinal, Neuroendocrine, Other Endocrine System, Unknown Sites
View Trial DetailsCLINICAL TRIAL 20010
IRONMAN: International Registry for Men with Advanced Prostate Cancer
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 20105
Using Radiogenomics to Noninvasively Predict the Malignant Potential of Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas and Uncover Hidden Biology
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 20156
Mindfulness in AYA Patients Undergoing Hematopoietic Stem Cell Transplantation: A Pilot Proposal
Disease Site: Multiple Myeloma, Unknown Sites, Leukemia, other
View Trial DetailsCLINICAL TRIAL 20256
CemiplimAb Survivorship Epidemiology (CASE) Study
Disease Site: Squamous Cell Carcinoma (SCC), Other Skin
View Trial DetailsCLINICAL TRIAL 20335
Physician Initiated Evaluation of EnVisio SmartClip for Intraoperative Localization of Breast Masses
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 20585
Development of a Quality of Life Decision-Making Model for Older Patients with Acute Myeloid Leukemia
Disease Site: Acute Leukemia (ALL, AML), Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 20788
An Advanced MRI Abdomen Protocol to Evaluate Pancreatic Ductal Adenocarcinoma in Surgically Resectable and Borderline Resectable Disease for Loco-Regional Heterogeneity and To Evaluate Treatment Response Status Post Surgery and MRI-GRT
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 20816
Multiple Myeloma Outcomes Based on Maintenance Therapy Post Autologous Stem Cell Transplant
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 20888
Predicting the Quality of Response to Specific Treatments (PQRST) Chronic GVHD Cohort
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21184
Thoracic Program Trial Selection Protocol
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 21233
The PAWN-Q Study: An Exploratory Analysis of Perceived Needs Regarding Physical Activity, Appearance, Weight, Nutrition, and Quality of Life in Adolescent and Young Adult Cancer Survivors
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21261
Characterizing the Gut Microbiome in Cancer Patients with Underlying HIV Infection
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21268
Biobanking for Breast Cancer Prevention and Disparity Research in Florida
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21353
A Prospective Randomized Trial Comparing Pre-Anesthesia Evaluation Remotely via Telemedicine Versus in Person for Surgical Patients at H. Lee Moffitt Cancer Center
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21448
Phase II Study of Screening Brain MRIs in Stage IV Breast Cancer
Disease Site: Breast, Brain metastasis
View Trial DetailsCLINICAL TRIAL 21552
Assessment of Cognition Performance in Adolescent and Young Adult Cancer Survivors
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21589
BASECAMP-1: An Observational Study Obtaining Solid Tumor Tissue from Subjects with Primary Surgical Resection and Leukapheresis for CAR T-Cell Therapy Manufacturing
Disease Site: Breast, Colon, Esophagus, Lip, Oral Cavity and Pharynx, Lung, Ovary, Pancreas, Rectum, Stomach
View Trial DetailsCLINICAL TRIAL 21610
The Influence of Psychosocial Factors on Opioid Decision-Making among Breast Cancer Survivors
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21737
A Pilot Study of Advanced Multi-parametric MRI to Evaluate De Novo Glioblastoma Tumors Prior to Surgical Resection
Disease Site: Brain and Nervous System, Gliomas
View Trial DetailsCLINICAL TRIAL 21752
Chimeric Antigen Receptor T-Cell Therapy: Neurocognitive Effects and Patient-Reported Outcomes
Disease Site: Hodgkin's Lymphoma, Leukemia, other, Lymphoid Leukemia, Multiple Myeloma, Myeloid and Monocytic Leukemia, Non-Hodgkin's Lymphoma, Other Hematopoietic
View Trial DetailsCLINICAL TRIAL 21760
Nutrition and Lifestyle Needs and Behaviors After Breast Cancer Diagnosis
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21783
A Pilot Study of Advanced Multi-Parametric MRI and MR Elastography to Evaluate Malignant Liver Tumors and Response to Neoadjuvant Therapy Prior to Surgical Resection
Disease Site: Liver
View Trial DetailsCLINICAL TRIAL 21786
The "COACH" Study: Individualized COaching in Young Adult Cancer Survivors to Encourage Healthy Behaviors
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21793
Cancer-Related Cognitive Impairment: Real-Time Evaluation and Assessment of Long-Term Impact of Treatment on Young Adult Survivors (CRCI REALITY)
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21876
Exploring Men s Prostate Cancer Genetic Risk Perceptions and Willingness to Give a Biospecimen for Genetic Risk Testing
Disease Site: Prostate
View Trial DetailsCLINICAL TRIAL 21962
Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 22083
Real-World Clinical and Patient-Reported Outcomes Among Patients With Relapsed/Refractory Multiple Myeloma treated With Commercial CAR-T Therapy
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 22156
The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 22157
A Mixed-Methods Study to Inform the Use of Patient Education and Digital Technology to Increase the Racial/Ethnic Diversity of Clinical Trial Participants
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 22176
Pilot to Create and Refine eHealth Genetic Education for Early-Onset Colorectal Cancer Patients (Nest-CRC Pilot)
Disease Site: Colon, Rectum
View Trial DetailsCLINICAL TRIAL 22179
Determinants of Cancer Survivorship Among People Living with HIV (HIV/AIDS/AGING/CANCER)
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 22334
Global Cardio Oncology Registry Protocol (G-COR)
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 17971
Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)
Disease Site: Lung
View Trial DetailsCLINICAL TRIAL 19000
Evaluation of Anti-Her2 and Anti-Her3 T-Helper Response in Primary Breast Cancer
Disease Site: Breast - Female
View Trial DetailsCLINICAL TRIAL 19724
Managed Access Program (MAP) To Provide Access To CTL019, For Acute Lymphoblastic Leukemia (ALL) Or Diffuse Large B-Cell Lymphoma (DLBCL) Patients With Out Of Specification Leukapheresis Product And/Or Manufactured Tisagenlecleucel Out Of Specification For Commercial Release
Disease Site: Acute Leukemia (ALL, AML), Leukemia, other
View Trial DetailsCLINICAL TRIAL 19950
Linking the Skin and Gut Microbiome to Immunosuppression in Skin Cancer
Disease Site: Other Skin
View Trial DetailsCLINICAL TRIAL 20003
LungMAP: A Master Protocol to Evaluate Biomarker-Driven Therapies And Immunotherapies In Previously-Treated Non-Small Cell Lung Cancer(Lung-MAP Screening Study)
Disease Site: Lung, Non small cell lung cancer
View Trial DetailsCLINICAL TRIAL 20187
Development of Intra-tumor Driver Mutation Prevalence as a Predictor of Efficacy of Targeted Agents
Disease Site: Reproductive System, Any Site
View Trial DetailsCLINICAL TRIAL 21065
Tumor Stroma in Pancreatic Adenocarcinoma
Disease Site: Any Site
View Trial DetailsCLINICAL TRIAL 21125
MElanoma Research Lymph Node Prediction Implementation National_001 (MERLIN_001)
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 21219
Predicting Progression of Developing Myeloma in a High-Risk Screened Population
Disease Site: Multiple Myeloma
View Trial DetailsCLINICAL TRIAL 21266
Gut Metabolome-Can it be Developed As A Biomarker of Response to Immunotherapy in Metastatic Renal Cell Cancer
Disease Site: Kidney
View Trial DetailsCLINICAL TRIAL 21351
A Prospective Analysis of Biochemical Markers for Hematopoietic Cell Transplant-Associated Thrombotic Microangiopathy in Adults
Disease Site: Unknown Sites
View Trial DetailsCLINICAL TRIAL 21452
Evaluating Gut Microbiome As A Biomarker Of Pathological Complete Response In Patients With Early Triple Negative Breast Cancer - A Pilot Study (TCC)
Disease Site: Breast
View Trial DetailsCLINICAL TRIAL 21561
Assessment of Chimerism and Relapse Post-Bone Marrow / Hematopoietic Cell Transplant (HCT) using ALLOHEME Test (ACROBAT)
Disease Site: Leukemia, other, Lymphoid Leukemia, Myeloid and Monocytic Leukemia
View Trial DetailsCLINICAL TRIAL 21908
A Systematic Review of Supplements Applicable in Treatment of Pancreatic Adenocarcinoma with Action on the mTOR Complex
Disease Site: Pancreas
View Trial DetailsCLINICAL TRIAL 21942
Characterization of Lymphoid Aggregates in Desmoplastic Melanoma
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 22258
Impact of Methotrexate Dosing on Acute Graft-Versus-Host Disease Risk in Allogeneic Hematopoietic Cell Transplant Patients
Disease Site: Bones and Joints
View Trial DetailsCLINICAL TRIAL 50401
Creation of Cell Lines and Corresponding DNA and RNA Analysis from Acral Lentiginous Malignant Melanoma
Disease Site: Melanoma, skin
View Trial DetailsCLINICAL TRIAL 50428
Metabolite Consumption in Patient-Derived Explants to Predict Therapeutic Response in Aggressive and Oligometastatic Prostate Cancer in African American Men
Disease Site: Prostate
View Trial Details
