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CLINICAL TRIAL 14690

Total Cancer Care Protocol: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer

Cancer Type: Cancer Control

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CLINICAL TRIAL 16933

Older Breast Cancer Patients: Risk For Cognitive Decline

Cancer Type: Breast

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CLINICAL TRIAL 16028

Transdisciplinary Research in Colorectal Cancer: The ColoCare Study

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 17716

A Biomarker-related Approach to Screening for HPV-related Oropharyngeal Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 16480

Radiomics: A Prospective Study of Outcome in Lung Cancer

Cancer Type: Multiple

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CLINICAL TRIAL 18523

A Validation Study on the Impact of Decipher® Testing on Treatment Recommendations in African-American and Non-African American Men with Prostate Cancer (VANDAAM Study)

Cancer Type: Genitourinary

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CLINICAL TRIAL 18331

Selection of Allogeneic Hematopoietic Cell Donors Based on KIR and HLA Genotypes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18494

A Phase I/II Study of Pembrolizumab and Vorinostat in Patients with Immune Therapy Naïve and Immune Therapy Pretreated Stage IV NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 18994

Phase II Randomized Trial of Radiotherapy with or without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) with TP53 Sequencing

Cancer Type: Head & Neck

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CLINICAL TRIAL 17970

A Randomized Phase III Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Observation for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

Cancer Type: Thoracic

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CLINICAL TRIAL 19072

A Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma (iNHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19181

Patient-Reported Outcomes in Immunotherapy for Head and Neck Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 19209

Combined Imaging and Blood Biomarkers for Breast Cancer Diagnosis

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 17723

Expansion of Enduring Infrastructure to Support Lung Cancer Screening Research

Cancer Type: Thoracic

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CLINICAL TRIAL 18979

Phase II Open-Label, Randomized Study of PARP inhibition (Olaparib) Either Alone or in Combination with Anti-PD-L1 Therapy (Atezolizumab; MPDL3280A) in Homologous DNA Repair (HDR) Deficient, Locally Advanced or Metastatic Non-HER2-positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19322

A Phase 1b Trial of Hu5F9-G4 Monotherapy or Hu5F9-G4 in Combination with Azacitidine in Patients with Hematological Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19456

Phase III Randomized Study of Crenolanib versus Midostaurin Administered Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed Subjects with FLT3 Mutated Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19327

A Phase 2 Trial of Pembrolizumab Plus Bevacizumab in Patients with Metastatic Melanoma or Non-small Cell Lung Cancer with Untreated Brain Metastases

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 18752

ACTION Trial- Adoptive Cellular Therapy following Dose-Intensified Temozolomide in Newly-diagnosed Pediatric High-grade Gliomas (Phase I)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19319

InPACT- International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)

Cancer Type: Genitourinary

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CLINICAL TRIAL 19360

Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant (ASCENT): A Phase 2 Trial of Induction, Consolidation and Maintenance in Subjects with High Risk Smoldering Multiple Myeloma (SMM)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19462

An Open-Label, First-in-Human, Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Maximum Tolerated Dose and / or Recommended Phase II Dose of the ATR Inhibitor BAY 1895344 in Patients with Advanced Solid Tumors and Lymphomas

Cancer Type: Multiple

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CLINICAL TRIAL 19365

Phase I Trial of the LSD1 inhibitor SP-2577 in Patients with Relapsed or Refractory Ewing Sarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 19627

A Randomized Phase III Trial of Consolidation with Autologous Hematopoietic Cell Transplantation Followed by Maintenance Rituximab vs. Maintenance Rituximab Alone for Patients with Mantle Cell Lymphoma In Minimal Residual Disease-Negative First Complete Remission

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19737

S1712, " A Randomized Phase II Study of Ruxolitinib in Combination with BCR-ABL Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Patients with Evidence of Molecular Disease.- Study Chairs: Kendra Sweet, M.D., Jerald P. Radich, M.D.

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19754

A Phase 3, Randomized, Open-label Study of NKTR-214 Combined with Nivolumab Versus Nivolumab in Participants with Previously Untreated Unresectable or Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19622

Phase II Trial of Investigational Agents to Modulate Intermediate Endpoint Biomarkers, Including Pulmonary Nodules, in Former Smokers

Cancer Type: Thoracic

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CLINICAL TRIAL 17971

Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)

Cancer Type: Thoracic

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CLINICAL TRIAL 19662

Phase II study of stereotactic body radiation therapy and atezolizumab in the management of recurrent, persistent, or metastatic cervical cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19495

A Multicenter, Randomized, Double Blinded, Placebo Controlled, Phase 3 trial of Adjuvant Avelumab (anti PDL1 antibody) in Merkel Cell Carcinoma Patients with Clinically Detected Lymph Node Metastases

Cancer Type: Cutaneous

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CLINICAL TRIAL 19630

Development of a Mindfulness-Based Treatment for the Reduction of Alcohol Use and Smoking Cessation

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19681

Community Outreach: Novel Tracking of INdividuals to Understand and Assess Results (CONTINUAR)

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19948

A Phase 2 Study of Atezolizumab and Cobimetinib in PD-1/PD-L1 Inhibitor Resistant or Refractory Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19646

Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer, Phase III

Cancer Type: Breast

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CLINICAL TRIAL 18906

A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an anti-TIM-3 Monoclonal Antibody, in Patients with Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 18778

A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20003

LungMAP: A Master Protocol to Evaluate Biomarker-Driven Therapies And Immunotherapies In Previously-Treated Non-Small Cell Lung Cancer(Lung-MAP Screening Study)

Cancer Type: Thoracic

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CLINICAL TRIAL 19936

Maintenance Systemic Therapy versus Local Consolidative Therapy (Lct) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (Nsclc): A Randomized Phase II/III Trial

Cancer Type: Genitourinary

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CLINICAL TRIAL 19717

The Florida Pancreas Collaborative Next-Generation Biobank: Reducing Health Disparities and Improving Survival for Pancreatic Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19962

A Phase 1 Study Evaluating the Safety and Efficacy of HPV16 E7 T Cell Receptor Engineered T Cells (KITE-439) in HLA-A*02:01+Subjects with Relapsed/Refractory HPV16+ Cancers

Cancer Type: Head & Neck

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CLINICAL TRIAL 19940

A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients with Recurrent Small Cell Lung Cancer: Big Ten Cancer Research Consortium BTCRC-LUN17-127

Cancer Type: Thoracic

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CLINICAL TRIAL 19473

Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Stage III-IVB Head and Neck Cancer with a Contraindication to Cisplatin

Cancer Type: Head & Neck

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CLINICAL TRIAL 19692

A Prospective, Randomised, Controlled, Open-label, Multicentre Phase III Study to Evaluate Efficacy and Safety of Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-Edotreotide Compared to Targeted Molecular Therapy with Everolimus in Patients with Inoperable, Progressive, Somato-Statin Receptor-Positive (SSTR+), Neuroendocrine Tumours of Gastroenteric or Pancreatic Origin (GEP-NET)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20015

Change in Relative Cerebral Blood Volume as a Biomarker for Early Response to Bevacizumab in Patients with Recurrent Glioblastoma

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19158

A Pilot Study of Atezolizumab (MPDL3280A) Following Adoptive Cell Transfer in Active Hematologic or Solid Tumor Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19406

Phase I/II Study of Nivolumab and Ipilimumab combined with Nintedanib in Non Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19694

Phase II Study of Nivolumab and Ramucirumab for Patients with Previously-Treated Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL 19877

A Randomized Phase 2 Study of CDX-1127 (Varlilumab) in Combination with Nivolumab in Patients with Relapsed or Refractory Aggressive B-Cell Lymphomas

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19958

Phase I/II Study of Dabrafenib, Trametinib, and Navitoclax in BRAF Mutant Melanoma (Phase I and II) and Other Solid Tumors (Phase I only)

Cancer Type: Cutaneous

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CLINICAL TRIAL 20040

A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19855

The AIM-HN and SEQ-HN Study: A 2 Cohort, Non-comparative, Pivotal Study Evaluating the Efficacy of Tipifarnib in Patients with Head and Neck Squamous Cell Carcinoma(HNSCC) with HRAS Mutations (AIM-HN) and the Impact of HRAS Mutations on Response to First Line Systemic Therapies for HNSCC (SEQ-HN)

Cancer Type: Head & Neck

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CLINICAL TRIAL 19715

An Open-Label, Randomized, Multicenter, Phase Ib/II Trial Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Mosunetuzumab (Btct4465a) In Combination With Polatuzumab Vedotin In Patients With B-Cell Non-Hodgkin Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19570

A Phase II Trial of Pembrolizumab and Cabozantinib in Patients with RM SCCHN

Cancer Type: Head & Neck

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CLINICAL TRIAL 20087

A Randomized, Double-Blind, Phase 3 Trial Of Maintenance With Selinexor/Placebo After Combination Chemotherapy For Patients With Advanced Or Recurrent Endometrial Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19435

Combination of Nivolumab Immunotherapy with Radiation Therapy and Androgen Deprivation Therapy in the Management of Gleason Group 5 Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 19389

A Phase 1, First-in-Human, Open-Label, Dose Escalation Study of JNJ-61186372, a Human Bispecific EGFR and cMet Antibody, in Subjects with Advanced Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 19837

Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients with Soft Tissue Sarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 18304

A Phase II Trial of AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 20081

Patterns of Cannabis Use in Young Adult Cancer Patients

Cancer Type: Multiple

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CLINICAL TRIAL 20041

A Randomized, Multicenter, Phase III Trial of Tacrolimus/Methotrexate versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19981

A Randomized Phase II Study of Atezolizumab (MPDL3280A) plus Recombinant Human IL-7 (CYT107) in patients with locally advanced or metastatic urothelial carcinoma

Cancer Type: Genitourinary

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CLINICAL TRIAL 19802

A Phase 1/2 Feasibility And Safety Study Of PSCA-Specific Chimeric Antigen Receptor Engineered T Cells (BPX-601) In Subjects With Non-Resectable Pancreatic Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20126

Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (CTRL-ALT-D)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20069

A Phase 1, Multi-center, Open-label, Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of an Orally Available Small Molecule CC-99282 Alone and in Combination with Rituximab in Subjects with Relapsed and/or Refractory Diffuse Large B Cell Lymphoma (R/R DLBCL) and Indolent Non-Hodgkin Lymphoma (R/R iNHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19724

Managed Access Program (MAP) To Provide Access To CTL019, For Acute Lymphoblastic Leukemia (ALL) Or Diffuse Large B-Cell Lymphoma (DLBCL) Patients With Out Of Specification Leukapheresis Product And/Or Manufactured Tisagenlecleucel Out Of Specification For Commercial Release

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20030

A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 19648

Phase IB Study of Avelumab with Radiotherapy in Patients with Leptomeningeal Disease

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20007

Utilizing Augmented Reality as an Adjunct for Smoking Cessation; Development and Initial Validation

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 20163

EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non©\Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNature©\driven Analysis

Cancer Type: Thoracic

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CLINICAL TRIAL 20178

An Open-Label Randomized Phase II Study of Combining Osimertinib with and without Ramucirumab in TKI-naïve EGFR-mutant Locally Advanced or Metastatic NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 18783

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20098

A Phase 3 Study of Pembrolizumab in Combination with Pemetrexed/Platinum (Carboplatin or Cisplatin) Followed by Pembrolizumab and Maintenance Olaparib vs Maintenance Pemetrexed in the First-Line Treatment of Participants with Metastatic Nonsquamous Non-Small-Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 18964

Randomized Double-Blind Phase III Study of Ibrutinib During and Following Autologous Stem Cell Transplantation Versus Placebo in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma of the Activated B-cell Subtype

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19989

Targeted Intra-arterial Gemcitabine vs. Continuation of IV Gemcitabine plus Nab-Paclitaxel following Induction with sequential IV Gemcitabine plus Nab-Paclitaxel and Radiotherapy for Locally Advanced Pancreatic Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20099

A Phase 3 Study of Pembrolizumab in Combination with Carboplatin/Taxane (Paclitaxel or Nab-paclitaxel) Followed by Pembrolizumab with or without Maintenance Olaparib in the First-line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 20168

HORMONET: Phase II Study of Hormone Therapy with Tamoxifen in Patients with well Differentiated Neuroendocrine Tumors and Hormone Receptor Positive Expression

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20149

A Phase 1/2, Open-Label, Multi-Center, First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Anti-Tumor Activity of TPX-0005 in Patients with Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements (TRIDENT-1)

Cancer Type: Thoracic

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CLINICAL TRIAL 20017

A Randomized Phase 2 Study of Bevacizumab and Either Weekly Anetumab Ravtansine or Weekly Paclitaxel in Platinum-Resistant or Platinum Refractory Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19956

A Phase 1b Trial of CB-839 in Combination with Radiation Therapy and Temozolomide in Patients with IDH-mutated Diffuse Astrocytoma and Anaplastic Astrocytoma

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19414

A Phase 2 Study of Talimogene Laherparepvec (T-VEC) and Radiation in Localized Soft Tissue Sarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 20130

Phase II Study of Daratumumab Based Response Adapted Therapy for Older Adults with Newly Diagnosed Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19150

A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 and TGR-1202 alone in Patients A Phase 2b Randomized Study to Assess the Efficacy and Safety of the Combination of Ublituximab + TGR-1202 With or Without Bendamustine and TGR-1202 Alone in Patients With Previously Treated Non-Hodgkin's Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19377

A Phase 1b/2 Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of AMG 592 in Adult Subjects With Steroid Refractory Chronic Graft versus Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20078

A Phase 3, Randomized, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of Stereotactic Body Radiotherapy (SBRT) with or without Pembrolizumab (MK-3475) in Participants with Medically Inoperable Stages I or IIA Non Small Cell Lung Cancer (NSCLC) (KEYNOTE-867)

Cancer Type: Thoracic

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CLINICAL TRIAL 20070

A Phase 3, Randomized, Double-blind Trial of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (KEYNOTE-641)

Cancer Type: Genitourinary

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CLINICAL TRIAL 20253

Open Label, Multi-Center, Phase 1b Clinical Trial to Evaluate the Safety and Efficacy of Autologous CAR-BCMA T cells (CT053) in Patients With Relapsed and/or Refractory Multiple Myeloma

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL 20274

A Phase II/III Randomized Study of Maintenance Nivolumab versus Observation in Patients with Locally Advanced, Intermediate Risk HPV Positive OPCA

Cancer Type: Head & Neck

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CLINICAL TRIAL 20174

A Phase I, Open-Label, Dose Finding Study To Assess The Safety, Tolerability, Pharmacokinetics, And Preliminary Efficacy Of OBT076, A CD205-Directed Antibody-Drug Conjugate, In Recurrent And/Or Metastatic CD205 Positive Solid Tumors And In Women With CD205 Positive HER2-Negative Metastatic Breast Cancer

Cancer Type: Multiple

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CLINICAL TRIAL 20131

Reduced-Intensity Fludarabine, Melphalan, and Total Body Irradiation Conditioning for Transplantation of HLA-Haploidentical Related Hematopoietic Cells (Haplo-HCT) For Patients With Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19660

Treatment Free Remission After Combination Therapy with Ruxolitinib Plus Tyrosine Kinase Inhibitors in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19579

Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy Fractionation for Patients with HPV+ Oropharyngeal Cancers.

Cancer Type: Head & Neck

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CLINICAL TRIAL 20251

A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR T cells in subjects with Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma (SPEARHEAD 1 Study)

Cancer Type: Immunotherapy

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CLINICAL TRIAL 20117

A Phase 1/2 Study of Regn5678 (Anti-psmaxcd28) with Cemiplimab (Anti-pd-1) in Patients with Metastatic Castration-Resistant Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 19585

A Phase 2 Study to Assess the Efficacy, Safety, Pharmacokinetic and Pharmacodynamic Parameters of Umbralisib in Treatment Naïve Patients with Chronic Lymphocytic Leukemia (CLL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20187

Development of Intra-tumor Driver Mutation Prevalence as a Predictor of Efficacy of Targeted Agents

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20175

A Two-arm, Randomized, Non-comparative, Phase 2 Trial of AGEN2034 (anti-PD-1) as a Monotherapy or Combination Therapy with AGEN1884 (anti-CTLA4) or with Placebo in Women with Recurrent Cervical Cancer (Second Line) - RaPiDS

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20300

A Phase 3, Randomized, Double-blind Study of Pembrolizumab (MK-3475) Plus Docetaxel Plus Prednisone versus Placebo Plus Docetaxel Plus Prednisone in Participants with Chemotherapy-naive Metastatic Castration-Resistant Prostate Cancer (mCRPC) who have Progressed on a Next Generation Hormonal Agent (NHA) (KEYNOTE- 921)

Cancer Type: Genitourinary

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CLINICAL TRIAL 18613

Phase II Study of nab-Paclitaxel in Combination with Gemcitabine for Treatment of Recurrent/Refractory Sarcoma in Teenagers and Young Adults

Cancer Type: Sarcoma

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CLINICAL TRIAL 19428

A Phase 1/2, Multicenter, Dose-Escalation and Expansion Study of Combination Therapy with Venetoclax, Daratumumab and Dexamethasone (With and Without Bortezomib) in Subjects with Relapsed or Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20162

Phase 1 Trial of Intralesional Immunotherapy with IFx-Hu2.0 Vaccine in Patients with Advanced Merkel Cell Carcinoma or Cutaneous Squamous Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 19305

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19477

A Phase II study of TAS 102 in Combination with Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19684

A Phase I/Ib, Open-Label, Multi-Center Study of NZV930 as a Single Agent and in Combination with PDR001 and/or NIR178 in Patients with Advanced Malignancies

Cancer Type: Thoracic

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CLINICAL TRIAL 19708

Biological Outcomes of Pramlintide in Resectable Cutaneous Squamous Cell Carcinoma: A Pilot Study

Cancer Type: Cutaneous

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CLINICAL TRIAL 20347

A phase 2 basket trial of glutaminase inhibitor (BeGIN) CB-839 HCl in patients with NF1 Aberrations, NF1 mutant malignant peripheral nerve sheath tumors (MPNST), KEAP1/NRF2 and LKB1 Aberrant tumors

Cancer Type: Sarcoma

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CLINICAL TRIAL 20315

Phase II Study of XL184 (cabozantinib) in combination with Nivolumab and Ipilimumab (CaboNivoIpi) in Patients with Radioiodine-refractory Differentiated Thyroid Cancer whose Cancer Progressed after One Prior VEGFR-Targeted Therapy

Cancer Type: Head & Neck

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CLINICAL TRIAL 19481

Phase I, Open Label Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Expansion, Persistence and Clinical Activity of UCART123 (Allogeneic Engineered T Cells Expressing anti-CD123 Chimeric Antigen Receptor), Administered in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20105

Using Radiogenomics to Noninvasively Predict the Malignant Potential of Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas and Uncover Hidden Biology

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20102

A Phase 2 Study of the Hepcidin Mimetic PTG-300 in Patients with Phlebotomy-Requiring Polycythemia Vera

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19137

A Randomized Phase II Trial of Abiraterone, Olaparib, or Abiraterone + Olaparib in Patients with Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects

Cancer Type: Genitourinary

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CLINICAL TRIAL 20132

Phase 1/2 Dose-Escalation and Expansion Study of FLX475 Alone and in Combination with Pembrolizumab in Advanced Cancer

Cancer Type: Multiple

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CLINICAL TRIAL 20278

A Single Arm, Open Label, Phase II Study of Ruxolitinib in Sclerotic Chronic Graft-Versus-Host Disease after Failure of Systemic Glucocorticoids

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19731

Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator Intervention for Neuro-Oncology Couples

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19746

A Multicenter, Open-Label, Dose Escalation Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of the DNA-PK Inhibitor M3814 in Combination with Avelumab with and without Palliative Radiotherapy in Participants with Selected Advanced Solid Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 20056

Phase II Clinical Trial of Green Tea Catechins in Men on Active Surveillance (AS)

Cancer Type: Genitourinary

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CLINICAL TRIAL 19873

A Phase II Open Label Single Arm Study of Adjuvant Nivolumab following Chemo-Radiation in localized Muscle-Invasive Bladder Cancer (NEXT)

Cancer Type: Genitourinary

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CLINICAL TRIAL 18094

A Phase 2 Study of Transarterial Chemoperfusion Treatment with Cisplatin, Methotrexate and Gemcitabine in Patients with Unresectable Pleural Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL 50337

Optimization of High-Grade Glioma Tissue Dissociation for the Maintenance of Cell Viability

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20314

A Phase 2 Study of Neoadjuvant Cemiplimab for Stage II to IV (M0) Cutaneous Squamous Cell Carcinoma (CSCC)

Cancer Type: Cutaneous

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CLINICAL TRIAL 20415

A Phase III, Open-Label, Multicenter, Randomized Study Evaluating The Saftey And Efficacy Of Polatuzumab Vedotin In Combination With RituximabI Plus Gemcitabine Plus Oxaliplatin (R-Gemox) Versus R-Gemox Alone In Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20372

Axicabtagene Ciloleucel:Neurocognitive and Patient-Reported Outcomes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 90001

A Phase 2, Multicenter, Single-Arm Study of Retreatment with Brentuximab Vedotin in Subjects with Relapsed or Refractory Classic Hodgkin lymphoma (cHL) or CD30-Expressing Peripheral T Cell Lymphoma (PTCL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20256

CemiplimAb Survivorship Epidemiology (CASE) Study

Cancer Type: Cutaneous

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CLINICAL TRIAL 20413

Phase III Study Of Daratumumab/Rhuph20 (Nsc- 810307) + Lenalidomide Or Lenalidomide As Post-Autologous Stem Cell Transplant Maintenance Therapy In Patients With Multiple Myeloma (MM) Using Minimal Residual Disease To Direct Therapy Duration (DRAMMATIC STUDY)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20397

A Phase 2, Single-Arm, Open-Label Study of Itacitinib, for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy

Cancer Type: Immunotherapy

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CLINICAL TRIAL 19870

A Phase 1, Multi-center, Open-label Study of IMGN632 Administered Intravenously in Patients with Relapsed/Refractory CD123-positive Acute Myeloid Leukemia and Other CD123-positive Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20622

REACT COVID-19: Real world Evidence for Anti-Cytokine Therapy in COVID-19, an International, Multi-center, Observational Study

Cancer Type: Multiple

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CLINICAL TRIAL 20258

A Phase 1 Dose Escalation With Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMV564 Alone and in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors

Cancer Type: Immunotherapy

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CLINICAL TRIAL 20585

Development of a Quality of Life Decision-Making Model for Older Patients with Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20266

A Phase 1a/1b Dose Escalation and Expansion Trial of TTI-621, a Novel Biologic Targeting CD47, in Subjects with Relapsed or Refractory Hematologic Malignancies and Selected Solid Tumors

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20474

A Phase 1b, First-in-Human, Dose Escalation and Expansion Study of XMT-1536 In Patients with Solid Tumors Likely to Express NaPi2b

Cancer Type: Thoracic

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CLINICAL TRIAL 20123

A Dose-Optimization, Exploratory Phase Ib/II Study to Assess Safety and Efficacy of the Second Mitochondrial-derived Activator of Caspases (SMAC) Mimetic Debio 1143, When Given in Combination with the Anti-PD-1 Antibody Nivolumab in Patients with Specific Solid Tumors who have Progressed During or Immediately after anti-PD-1/PD-L1 Treatment

Cancer Type: Multiple

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CLINICAL TRIAL 20576

A Phase 2 Study of MLN4924 (Pevonedistat) in Combination with Carboplatin and Paclitaxel in Advanced NSCLC Previously Treated with Immunotherapy

Cancer Type: Thoracic

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CLINICAL TRIAL 20377

A Phase 2 Multicohort Study of Nivolumab in Combination with Docetaxel and Androgen Deprivation Therapy in Metastatic Hormone Sensitive Prostate Cancer Patients with DNA Damage Repair Defects or Inflamed Tumors

Cancer Type: Genitourinary

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CLINICAL TRIAL 20364

A Phase 1/2 Study of REGN5093 in Patients with Met-Altered Advanced Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 20578

A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmocodynamics of ALLO-501A, an Anti-CD19 Allogeneic Car T Cell Therapy in Subjects with Relapsed/Refractory Large B-Cell Lymphoma (LBCL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19658

A Phase 1, Open-Label, Dose-Escalation with Expansion Study of SX-682 in Subjects with Myelodysplastic Syndrome Who Had Disease Progression or are Intolerant to Prior Therapy

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20159

A Phase 1 Study of ZW49 in Patients with Locally Advanced (Unresectable) or Metastatic HER2-Expressing Cancers

Cancer Type: Breast

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CLINICAL TRIAL 19429

A Phase 2 Single-Arm, Open-Label Study Evaluating Tolerability and Efficacy of Navitoclax in Combination with Ruxolitinib in Subjects with Myelofibrosis

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20485

A Motion Exergaming Approach to Promote Self-Managing Fatigue and Pain after Head and Neck Cancer Treatment

Cancer Type: Head & Neck

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CLINICAL TRIAL 20373

TH-138: Phase II Randomized Trial of Carboplatin + Pemetrexed + Bevacizumab, With or Without Atezolizumab in Stage IV Non-Squamous NSCLC Patients who Harbor a Sensitizing EGFR Mutation or Have Never Smoked

Cancer Type: Thoracic

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CLINICAL TRIAL 20529

A Randomised, Multicentre, Double-blind, Placebo-controlled, Phase III Study of First-line Carboplatin and Paclitaxel in Combination with Durvalumab, Followed by Maintenance Durvalumab with or without Olaparib in Patients with Newly Diagnosed Advanced or Recurrent Endometrial Cancer (DUO-E)

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20304

A Phase 1/2, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of AMG 510 Monotherapy in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation and AMG 510 Combination Therapy in Subjects With Advanced NSCLC With KRAS p.G12C Mutation (Codebreak 100)

Cancer Type: Thoracic

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CLINICAL TRIAL 20082

Pilot Trial of Enasidenib Maintenance Post Allogeneic Hematopoietic Cell Transplantation in Patients with IDH2 Mutation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18680

A study of Intravesical Bacillus Calmette-Guerin (BCG) in Combination with ALT-803 in Patients with Non-Muscle Invasive Bladder Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 20375

Phase I Study of APR-246 in Combination with Venetoclax and Azacitidine in TP53-Mutant Myeloid Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19117

A Multicenter Phase II Study of Vaccines to Prevent Recurrence in Patients with HER-2 Positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 20349

A Phase 2 Study of TAS-120 in Metastatic Breast Cancers Harboring Fibroblast Growth Factor Receptor (FGFR) Amplifications

Cancer Type: Breast

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CLINICAL TRIAL 20310

Family Building Decisions Among Adolescent Young Adults (AYAs) Patients with Inherited Cancer Risk and Their Partner Dyads

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 20385

A Phase III, Randomized Study of Nivolumab (Opdivo) Plus AVD or Brentuximab Vedotin(Adcetris) Plus AVD in Patients (Age >/= 12 years) with Newly Diagnosed Advanced Stage Classical Hodgkin Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20361

A Phase 1, Open-Label, Multi-Center, Dose Escalation and Dose Expansion Study of NKTR-255 As A Single Agent In Relapsed Or Refractory Hematological Malignancies and In Combination With Daratumumab As A Salvage Regimen for Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20619

A Phase 2 Multicenter, Open-label Study of Rucaparib as Treatment for Solid Tumors Associated with Deleterious Mutations in Homologous Recombination Repair Genes (LODESTAR)

Cancer Type: Multiple

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CLINICAL TRIAL 20313

Neoadjuvant Immunotherapy with Intratumoral Tavokinogene Telseplasmid (Tavo) plus Electroporation in Combination with Intravenous Nivolumab in Patients with Operable Locally- Regionally Advanced Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20763

NCI COVID-19 in Cancer Patients Study (N-CCaPS): A Longitudinal Natural History Study

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 17431

A Randomized Phase 3 Study of the Efficacy and Safety of Glufosfamide Compared with Fluorouracil (5-FU) in Patients with Metastatic Pancreatic Adenocarcinoma Previously Treated with Gemcitabine

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19988

A Phase II Open Label, Study of IMMU-132 in Metastatic Urothelial Cancer After Failure of Platinum-Based Regimen or Anti-PD-1/ PD-L1 Based Immunotherapy

Cancer Type: Genitourinary

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CLINICAL TRIAL 19970

A Pilot Trial of Intratumorally-Administered Topotecan using Convection-Enhanced Delivery (CED) in Patients with Suspected Recurrent/Progressive WHO Grade III or IV (High Grade) Glioma Undergoing Stereotactic Biopsy (IND 117,240)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19967

A Phase I, Multi-Center, Open-Label, Treatment Duration Increment, Expansion, Safety, and Pharmacodynamic Study of CX-4945 Administered Orally Twice Daily to Patients with Advanced Basal Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20348

Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III randomized study of chemoradiation versus chemoradiation plus Atezolizumab

Cancer Type: Thoracic

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CLINICAL TRIAL 18874

A Phase 1b/2 Study to Assess the Safety and Efficacy of HBI-8000 in Combination with Nivolumab in Patients with Advanced Solid Tumors Including Melanoma, Renal Cell Carcinoma (RCC) and Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Cutaneous

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CLINICAL TRIAL 20533

A Phase 1, Open-Label, Multicenter, Dose Escalation and Expansion Study of ONCR-177, an Oncolytic Herpes Simplex Virus for Intratumoral Injection, Alone and in Combination with PD-1 Blockade in Adult Subjects with Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 18741

Randomized Embolization Trial for NeuroEndocrine Tumor Metastases To The Liver (RETNET): A Phase 3 Randomized Multicenter Trial to Compare Hepatic Progression-Free Survival Following Bland Embolization, Lipiodol Chemoembolization, and Drug-Eluting Bead Chemoembolization of Neuroendocrine Liver Metastases

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20339

Evolutionary Inspired Therapy for Newly Diagnosed, Metastatic, Fusion Positive Rhabdomyosarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 20497

A Multicenter, Open-Label Phase 1/2 Trial Evaluating the Safety, Tolerability and Efficacy of MORAb-202, a Folate Receptor Alpha (FRA)-Targeting Antibody-Drug Conjugate (ADC) in Subjects with Selected Tumor Types

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20498

Immune Checkpoint Blockade for Kidney Transplant Recipients with Selected Unresectable or Metastatic Cancers

Cancer Type: Cutaneous

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CLINICAL TRIAL 20156

Mindfulness in AYA Patients Undergoing Hematopoietic Stem Cell Transplantation: A Pilot Proposal

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL 20297

Cabozantinib plus Pembrolizumab as First-Line Therapy for Cisplatin-Ineligible Advanced Urothelial Carcinoma (PemCab)

Cancer Type: Genitourinary

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CLINICAL TRIAL 20270

A Phase 2, Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (LN-144 or LN-145) in Patients with Solid Tumors (IOV-COM-202)

Cancer Type: Immunotherapy

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CLINICAL TRIAL 19872

A Phase 3, Open-Label, Randomized Study To Compare The Efficacy And Safety Of Luspatercept (Ace-536) Versus Epoetin Alfa for the Treatment Of Anemia Due To IPSS-R Very Low, Low Or Intermediate Risk Myelodysplastic Syndromes (Mds) In Esa Naïve Subjects Who Require Red Blood Cell Transfusions The Commands Trial

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19379

A Phase 2, Multicenter, Open-Label Study To Evaluate The Efficacy And Safety Of Luspatercept (Ace-536) In Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis And Anemia With And Without Red Blood Cell-Transfusion Dependence

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19748

Phase II Randomized Trial of Radiotherapy with Concurrent and Adjuvant Pembrolizumab (Keytruda®) Versus Concurrent Chemotherapy in Patients with Advanced/Intermediate-Risk p16+ Head and Neck Squamous Cell Carcinoma (KEYCHAIN Trial)

Cancer Type: Head & Neck

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CLINICAL TRIAL 18356

A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients who have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL 20306

A Phase 2 Open-Label, Multicenter, Study to Evaluate the Efficacy and Safety of Rivoceranib in Subjects with Recurrent or Metastatic Adenoid Cystic Carcinoma of All Anatomic Sites of Origin

Cancer Type: Head & Neck

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CLINICAL TRIAL 19878

A Phase II Study of Talimogene Laherparepvec (T-VEC) in the Treatment of Locally Advanced Cutaneous Angiosarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 20286

A Phase III Multi-Center, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Lutathera in Patients with Grade 2 and Grade 3 Advanced GEP-NET

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19482

A Single-Arm, Open-Label Phase 2 Pilot Study of Vyxeos (CPX-351) in Adults with Relapsed or Refractory Acute Lymphoblastic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20767

Integration of Immunotherapy into Adjuvant Therapy For Resected NSCLC: Alchemist Chemo-IO

Cancer Type: Thoracic

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CLINICAL TRIAL 19722

A Phase 2, Multi-Cohort, Open-Label, Multicenter Study To Determine The Efficacy And Safety Of Bb2121 In Subjects With Relapsed And Refractory Multiple Myeloma And In Subjects With High-Risk Multiple Myeloma Having Progressed Within One Year Of Initial Treatment

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20788

An Advanced MRI Abdomen Protocol to Evaluate Pancreatic Ductal Adenocarcinoma in Surgically Resectable and Borderline Resectable Disease for Loco-Regional Heterogeneity and To Evaluate Treatment Response Status Post Surgery and MRI-GRT

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19943

Somatostatin receptor expression in poorly-differentiated neuroendocrine carcinomas of the GI tract: analysis using 68Ga-dotatate PET scan

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19974

Contrast-Enhanced Ultrasound for the Evaluation of Changes in Tumor Blood Flow and the Surrounding Hepatic Parenchyma before, during and after Hepatic Artery Embolization

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19683

A Phase 1, Open-Label, Multicenter, Dose-Escalation Study of RMC-4630 Monotherapy in Adult Participants with Relapsed/Refractory Solid Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 20551

Bright IDEAS-Young Adults: Problem-Solving Skills Training to Reduce Distress Among Young Adults with Cancer

Cancer Type: Multiple

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CLINICAL TRIAL 20787

Health Literacy, Home Environmental Influence and Ethnicity and its Association to Adherence to Nutrition and Physical Exercise Guidelines in Adolescents and Young Adults Cancer Patients and Survivors: An Exploratory Study

Cancer Type: Multiple

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CLINICAL TRIAL 20845

Health Insurance Literacy in Head and Neck Cancer Patients

Cancer Type: Head & Neck

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CLINICAL TRIAL 18959

A Phase 2 Study to Evaluate the Safety, Tolerability and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-145) followed by IL-2 in Patients with Recurrent and/or Metastatic Cervical Carcinoma

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19635

A Phase 1b/2 Study Evaluating the Safety and Efficacy of Intravenous LB-100 in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) who had Disease Progression or are Intolerant to Prior Therapy

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 18786

A Phase 2, Randomized, Multi-institutional Study of Nivolumab and Ipilimumab versus Nivolumab, Ipilimumab and Stereotactic Body Radiation Therapy for Metastatic Merkel Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20332

Activity and Enhancement of Immune Checkpoint Inhibition with Lurbinectedin in Relapsed/Recurrent Small Cell Lung Cancer (SCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 20345

Phase I/II Trial of Pre-Operative Image Guided Intensity Modulated Proton Radiation Therapy (IMPT) or Photon (IMRT) with Simultaneously Integrated Boost to the High Margin for Retroperitoneal Sarcomas

Cancer Type: Sarcoma

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CLINICAL TRIAL 20287

A Phase 1b/2 Study of IMGN632 as Monotherapy or Combination with Venetoclax and/or Azacitidine for Patients with CD123-Positive Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20499

Pivotal Study of the Lum Imaging System For Assisting Intraoperative Detection of Residual Cancer in the Tumor Bed of Female Patient with Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 20110

GBM Agile: Global Adaptive Trial Master Protocol

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20575

A Phase 1 Study of CG0070 Combined with Nivolumab in Cisplatin Ineligible Patients with Muscle Invasive Bladder Cancer (MIBC)

Cancer Type: Genitourinary

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CLINICAL TRIAL 20050

QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination with ALT-803 in Patients with BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 17268

I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2)

Cancer Type: Breast

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CLINICAL TRIAL 20145

A Pilot Study of Intratumorally and Intraparenchymally Administered OS2966 using Convection-enhanced Delivery in Patients with Recurrent/Progressive High-grade Glioma Undergoing a Clinically-indicated Surgical Resection

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 20419

Phase II Study of Short Course FOLFOX Chemotherapy with Either Nivolumab or Nivolumab + Radiation in the First Line Treatment of Metastatic or Unresectable Gastroesophageal Cancers (BMS Protocol CA209-76L)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20562

A Randomized, Controlled, Open-Label, Phase 2 Study of Cemiplimab as a Single Agent and in Combination with RP1 in Patients with Advanced Cutaneous Squamous Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20026

A Phase I Study of NBTXR3 Activated by Radiotherapy for Patients with Advanced Cancers Treated with an Anti-PD1 Therapy

Cancer Type: Thoracic

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CLINICAL TRIAL 19829

A Phase 1/2a, Open-label, Dose-escalation, Dose-expansion, Parallel Assignment Study to Evaluate the Safety and Clinical Activity of PBCAR0191 in Subjects with Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19814

A Phase 2, Open-Label, Multi-Center Study of Al101 (BMS-906024) in Patients with Adenoid Cystic Carcinoma (ACC) Bearing Activating Notch Mutations

Cancer Type: Head & Neck

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CLINICAL TRIAL 20557

A Phase II, Open-Label, Multicenter, Randomized Study of Efficacy and Safety of RO7198457 in Combination with Pembrolizumab versus Pembrolizumab in Patients with Previously Untreated Advanced Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20637

Phase III Trial of Post-Surgical Single Fraction Stereotactic Radiosurgery (SRS) Compared with Fractionated SRS (FSRS) for Resected Metastatic Brain Disease

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL 19732

Randomized, Double-Blinded Phase III Study of Cabozantinib Versus Placebo in Patients with Advanced Neuroendocrine Tumors after Progression on Everolimus (Cabinet)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20402

A Phase 3, Randomized, Double-blind Study of Neoadjuvant Chemotherapy plus Nivolumab versus Neoadjuvant Chemotherapy plus Placebo, followed by Surgical Resection and Adjuvant Treatment with Nivolumab or Placebo for Participants with Resectable Stage II-IIIB Non-small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 20608

A Phase 1/2 Study Evaluating the Safety and Efficacy of IOV-2001 in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20579

Phase 1 / 2 Multicenter Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of APL-101 in Subjects with Non-Small Cell Lung Cancer with c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL 20487

Phase I/II Study of Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in the Management of HER2+ Breast Leptomeningeal Disease

Cancer Type: Breast

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CLINICAL TRIAL 20042

CD8 Depleted, Non-Engrafting, HLA Mismatched Unrelated Donor Lymphocyte Infusion in Patients with MDS and Secondary AML

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 50376

Pilot Study of Using MRD as a Predictor of Response after Axicabtagene Ciloleucel in Patients with Indolent Lymphomas

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20907

Investigation of molecular and clinical biomarkers of colorectal and pancreatic cancer in flatiron database

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20631

Randomized Prospective Trial of Breast Cancer Locator Guided vs. Wire Localized Partial Mastectomy for Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 20022

Feasibility Study for Electroacupuncture for Chemotherapy- Induced Peripheral Neuropathy (CIPN) Using a Point-Of-Nerve Conduction Device (NeuroMetrix) and the Rydel-Seiffer Tuning Fork

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20628

A Phase II, Open-Label, Study to Assess the Efficacy, Safety, and Tolerability of AZD4635 in Combination with Durvalumab and in Combination with Cabazitaxel and Durvalumab in Patients Who Have Progressive Metastatic Castrate-Resistant Prostate Cancer (AARDVARC)

Cancer Type: Genitourinary

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CLINICAL TRIAL 20254

A Phase 1b/2, Open-Label Study Evaluating the Safety and Efficacy of KRT-232 in Patients with p53 Wild-Type (p53WT) Merkel Cell Carcinoma (MCC) Who Have Failed Anti-PD-1 or Anti-PD-L1 Immunotherapy, or in Combination with Avelumab in MCC Patients who are Anti-PD-1 or Anti-PD-L1 Treatment Naive

Cancer Type: Cutaneous

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CLINICAL TRIAL 20292

A Phase 1/2, Open-label, Dose-Escalation and Dose-Expansion Cohort Study of SNDX-5613 in Patients with Relapsed/Refractory Leukemias, Including Those Harboring an MLL/KMT2A Gene Rearrangement or Nucleophosmin 1 (NPM1) Mutation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20528

Prospective, Interventional Pilot Study of Mobile Devices and Digital Applications to Detect Early Pneumonitis and Other Pulmonary Adverse Events in Unresectable Stage III Non-Small Cell Lung Cancer Patients on Durvalumab

Cancer Type: Thoracic

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CLINICAL TRIAL 20094

EDRN Prostate MRI Biomarker Study and Reference Set

Cancer Type: Multiple

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CLINICAL TRIAL 21064

Gastrointestinal Oncology Transformative Initiatives for Translation (GOTIT): A Cloud-based Datamart for Rapid and Efficient Acquisition of Data to Enhance Clinical Care and Inform Research Advances

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20284

Use of Water as an Oral Contrast Agent for Abdominopelvic Computed Tomography in Patients with Cancer

Cancer Type: Multiple

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CLINICAL TRIAL 20885

A Phase 2 Study of XL184 (Cabozantinib) in Combination with Nivolumab and Ipilimumab for the Treatment of Poorly Differentiated Neuroendocrine Carcinomas

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20826

S1701, A Randomized Phase II Trial of Carboplatin-Paclitaxel with or without Ramucirumab in Patients with Unresectable Locally Advanced, Recurrent, or Metastatic Thymic Carcinoma

Cancer Type: Thoracic

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CLINICAL TRIAL 20720

S1827, MRI Brain Surveillance Alone Versus MRI Surveillance and Prophylactic Cranial Irradiation (PCI): A Randomized Phase III Trial in Small-Cell Lung Cancer (MAVERICK)

Cancer Type: Thoracic

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CLINICAL TRIAL 19960

A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmacodynamics of ALLO-501, an Anti-CD19 Allogeneic Car T Cell Therapy, and ALLO-647, an Anti-CD52 Monoclonal Antibody, in Patients with Relapsed/Refractory Large B-Cell and Follicular Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20171

A Phase 1/2, Open-label, Dose Escalation, and Cohort Expansion Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of ARV-471 in Patients with ER+/HER2- Locally Advanced or Metastatic Breast Cancer, Who Have Received Prior Hormonal Therapy and Chemotherapy in the Locally Advanced/Metastatic Setting

Cancer Type: Breast

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CLINICAL TRIAL 19356

A Phase 1b Trial of the IRX-2 Regimen and Durvalumab (MEDI4736), in Patients with Incurable Head and Neck Squamous Cell Carcinoma

Cancer Type: Head & Neck

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CLINICAL TRIAL 20600

A Phase I, Open-Label, Multicenter, Dose Escalation, Dose Expansion Study of PRT543 in Patients with Advanced Solid Tumors and Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19862

A Phase 1/1b Safety Study of PRGN-3006 Adoptive Cellular Therapy in Patients with Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndrome

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19815

A Phase I Safety and Window-of-Opportunity Study of Preoperative Intra-tumoral Injection of OX40-Ligand Expressing Oncolytic Adenovirus (DNX-2440) in Patients with Resectable Liver Metastasis

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19480

The Reveal Study: A Phase 1/2, Open-Label, Multicenter, Dose Escalation And Dose Expansion Study Of Nktr-262 In Combination With Bempegaldesleukin (Nktr-214) And In combination With Bempegaldesleukin (Nktr-214) Plus Nivolumab In Patients With Locally Advanced Or Metastatic Solid Tumor Malignancies

Cancer Type: Multiple

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CLINICAL TRIAL 20173

A Phase 2, Multi-arm, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of IPI-549 Administered in Combination with Front-line Treatment Regimens in Patients with Locally Advanced and/or Metastatic Triple-Negative Breast Cancer or Renal Cell Carcinoma

Cancer Type: Breast

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CLINICAL TRIAL 20722

Phase III Randomized Trial of Pleurectomy/Decortication plus Chemotherapy with or without Adjuvant Hemithoracic Intenstiy-Modulated Pleural Radiation Therapy (IMPRINT) for Malignant Pleural Mesothelioma (MPM)

Cancer Type: Thoracic

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CLINICAL TRIAL 19942

Sequential Maintenance with Thoracic Radiotherapy and Durvalumab (MEDI4736) monotherapy or Durvalumab (MEDI 4736) Combinations (Tremelimumab or Olaparib) in Patients with Extensive Stage-Small Cell Lung Cancer after First Line Platinum Based Chemotherapy

Cancer Type: Thoracic

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CLINICAL TRIAL 20904

A Randomized Phase 2 Trial of Encorafenib + Binimetinib + Nivolumab vs Ipilimumab + Nivolumab in Braf-V600 Mutant Melanoma with Brain Metastases

Cancer Type: Cutaneous

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CLINICAL TRIAL 20730

Randomized, Double-blind, Phase 3 Study of Tucatinib or Placebo in Combination with Ado-Trastuzumab Emtansine (T-DM1) for Subjects with Unresectable Locally-Advanced or Metastatic HER2+ Breast Cancer (HER2CLIMB-02)

Cancer Type: Breast

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CLINICAL TRIAL 20114

A Single Arm Phase II Study of Cemiplimab-rwlc in Immunocompromised Patients with Unresectable Locally Recurrent and/or Metastatic Cutaneous Squamous Cell Carcinoma (CSCC)

Cancer Type: Head & Neck

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CLINICAL TRIAL 20925

Physician Adherence to Patient Safety Surveillance of Tyrosine Kinase Inhibitor Side Effects When Treating Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 21079

Head and Neck Cancer Pre-Surgery Education and Discharge Planning: Key Stakeholder Perceptions

Cancer Type: Head & Neck

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CLINICAL TRIAL 19961

A Phase 1B/2 Study To Evaluate The Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of Eq001 In Subjects With Newly Diagnosed Acute Graft Versus Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20571

Optimizing Cellular and Humoral Immunity to Pneumococcus by Vaccination with Pneumococcal 13-valent conjugate vaccine before and after CD19-targeted CAR T-cell Immunotherapy

Cancer Type: Immunotherapy

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CLINICAL TRIAL 20577

A Phase 1b/2, Open-Label, Multicenter Dose-Escalation and Dose-Expansion Study of the Combination of RMC-4630 and Cobimetinib in Adult Participants with Relapsed/Refractory Solid Tumors with Specific Genomic Aberrations

Cancer Type: Thoracic

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CLINICAL TRIAL 19487

A Phase Ib/II Study to Evaluate the Safety, Feasibility and Efficacy of Nivolumab or Nivolumab in Combination with Azacitidine in Patients with Recurrent, Resectable Osteosarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL 20641

A Randomized Pilot Trial of Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib and Binimetinib in Advanced Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20772

An Open-label Phase 1b/2a Study of NT-I7 (Hyleukin-7) in Combination with Pembrolizumab in Subjects with Relapsed/Refractory Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL 20479

Efficacy of SOAR (Survivors Overcoming and Achieving Resiliency) Survivorship Workshop for Breast Cancer Survivors

Cancer Type: Breast

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CLINICAL TRIAL 20733

A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzomab Ozogamicin (a conjugated anti-CD22 monoclonal antibody) to Frontline Therapy in Young Adults (ages 18-39 years) with Newly Diagnosed Precusor B-cell ALL

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 21085

Cervical Cancer: Understanding Patient and Provider Perspectives on Vaccine Based Treatment Trials

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 20489

A Phase II Study of TAS-102, Irinotecan and Bevacizumab in Pre-treated Metastatic Colorectal Cancer (TABAsCO)

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20851

A Phase 1, Multicenter, Open-Label Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Combinations of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Subjects with Locally Advanced or Metastatic Solid Tumors

Cancer Type: Breast

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CLINICAL TRIAL 20614

A Phase III, Multicneter, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Atezolizumab Given in Combination with Cabozantinib versus Cabozantinib Alone in Patients with Inoperable, Locally, Advanced, or Metastatic Renal Cell Carcinoma Who Experienced Radiographic Tumor Progression During or After Immune Checkpoint Inhibitor Treatment

Cancer Type: Genitourinary

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CLINICAL TRIAL 20837

Envasarc: A Pivitol Trial of Envafolimab, and Envafolimab in Combination with Ipilimumab, in Patients with Advanced or Metastatic Undifferentiated Pleomorphic Sarcoma or Myxofibrosarcoma Who Have Progressed on Prior Chemotherapy

Cancer Type: Sarcoma

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CLINICAL TRIAL 20484

A Phase 2 Study of Donor-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-401) Administered to Patients with Acute Myeloid Leukemia (AML) following Hematopoietic Stem Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19207

Phase II study of pembrolizumab and lenvatinib in advanced well-differentiated neuroendocrine tumors

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 20096

Composite Health Assessment Model for Older Adults: Applying Pre-transplant Comorbidity, Geriatric Assessment, and Biomarkers to Predict Non-Relapse Mortality after Allogeneic Transplantation (CHARM)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20605

A Phase 1b Efficacy and Safety Study of Cofetuzumab Pelidotin (ABBV-647, a PTK7-Targeting Antibody Drug Conjugate) in Subjects with PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL 21081

Assessing Distress in Family Caregivers of Patients Receiving Cellular Therapies

Cancer Type: Immunotherapy

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CLINICAL TRIAL 19125

A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL 19387

A Phase 2 Study of Poziotinib in Patients with Non-Small Cell Lung Cancer, (NSCLC), Locally Advanced or Metastatic, with EGFR or HER2 Exon 20 Insertion Mutation (ZENITH20)

Cancer Type: Thoracic

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CLINICAL TRIAL 20010

IRONMAN: International Registry for Men with Advanced Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL 19656

Phase I Study of Ceritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL 20490

Keystroke: A Randomized Phase II Study of Pembrolizumab (Keytruda) Plus Stereotactic Re-irradiation versus SBRT Alone For Locoregionally Recurrent or Second Primary Head and Neck Carcinoma

Cancer Type: Head & Neck

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CLINICAL TRIAL 18989

A Phase 1b/2 Study of PV-10 Intralesional Injection in Combination with Systemic Immune Checkpoint Inhibition for Treatment of Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 18992

A Phase II and Pilot Trial of PD-1 Blockade with MK-3475 (Pembrolizumab) in Patients with Resectable or Unsectable Desmoplastic Melanoma (DM)

Cancer Type: Cutaneous

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CLINICAL TRIAL 21148

Cancer Symptom Management Among Spanish-Speaking Patients

Cancer Type: Multiple

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CLINICAL TRIAL 21061

An Examination of Patient Reported Outcomes and Predictors Among Patients with Metastatic Melanoma Treated with Immune Checkpoint Inhibitors

Cancer Type: Cutaneous

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CLINICAL TRIAL 20363

A Phase 2a, Open-Label, Multi-Center Study to Assess the Efficacy and Safety of Marrow Infiltrating Lymphocytes NonSmall Cell Lung Cancer (MILs - SCLC) Alone or in Combination with Nivolumab in Subjects with Locally Advanced and Unresectable or Metastatic NSCLC Previously Treated with Anti-PD-1

Cancer Type: Immunotherapy

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CLINICAL TRIAL 18926

The National Myelodysplastic Syndromes (MDS) Study

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20144

A Phase 1, First-in-Human, Open-Label, Dose Escalation and Expansion Study of CUE-101 Monotherapy in Second Line and CUE-101 Combination Therapy with Pembrolizumab in First Line Patients with HPV16+ Recurrent / Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)

Cancer Type: Head & Neck

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CLINICAL TRIAL 19407

An Open-Label, Randomized, Controlled Multi-Center Study of The Efficacy of Daromun (L19IL2 + L19TNF) Neoadjuvant Intratumoral Treatment Followed by Surgery Versus Surgery Alone in Clinical Stage IIIB/C Melanoma Patients

Cancer Type: Cutaneous

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CLINICAL TRIAL 20552

A Phase 1b/2 Study Evaluating the Safety and Efficacy of Canakinumab with Darbepoetin alfa in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) who have Failed Erythropoietin Stimulating Agents (ESA)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20716

ENHANCE: A Randomized, Double-blind, Multicenter Study Comparing Magrolimab in Combination with Azacitidine versus Azacitidine Plus Placebo in Treatment-naïve Patients with Higher Risk Myelodysplastic Syndrome

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20634

A Randomized, Double-Blind, Phase 3 Study to Evaluate the Activity of Momelotinib (MMB) versus Danazol (DAN) in Symptomatic, Anemic Subjects with Primary Myelofibrosis (PMF), Post-Polycythemia Vera (PV)Myelofibrosis, or Post Essential Thrombocythemia (ET) Myelofibrosis who were Previously Treated with JAK Inhibitor Therapy

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 19733

Motivating a Spectrum of Cancer Patients to Quit Smoking: Intervention Development and Feasibility

Cancer Type: Multiple

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CLINICAL TRIAL 19337

A Pilot Study Utilizing a HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+ Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 20830

A Phase 2 Randomized, Multicenter, Double-Blind Study of the Glutaminase Inhibitor Telaglenastat with Pembrolizumab and Chemotherapy Versus Placebo with Pembrolizumab and Chemotherapy in First-Line, Metastatic KEAP1/NRF2-Mutated, Nonsquamous, Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL 20825

A First-in-human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients with Intrahepatic Cholangiocarcinoma (ICC) and Other Advanced Solid Tumors

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL 19441

Pilot Study of Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 20753

An Open-Label Phase I, Multi-Center Study to Determine the Recommended Dose of the Chimeric Antigen Receptor T-cell Treatment CYAD-211 After a Non-Myeloablative Preconditioning Chemotherapy in Multiple Myeloma Patients with Relapsed or Refractory Disease (IMMUNICY-1)

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL 20748

TENACITY- A Phase 2, Multicenter, Open-Label, Single-arm Study of AL101 Monotherapy in Patients with Notch-activated Triple Negative Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL 20337

Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living with HIV

Cancer Type: Healthy Subjects

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CLINICAL TRIAL 19475

Phase 1 Study of Trametinib + Ceritinib in Patients with Unresectable Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL 21030

A Randomized Phase 3 Study of Sitravatinib in Combination with Nivolumab Versus Docetaxel in Patients with Advanced Non-Squamous Non-Small Cell Lung Cancer with Disease Progression on or After Platinum-Based Chemotherapy in Combination with Checkpoint Inhibitor Therapy (SAPPHIRE)

Cancer Type: Thoracic

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CLINICAL TRIAL 20814

Brentuximab Vedotin with Cyclophosphamide, Doxorubicin, Etoposide, and Prednisone (BV-CHEP) for the Treatment of Adult T-Cell Leukemia/Lymphoma: A Pilot Study of the Rare Lymphoma Working Group

Cancer Type: Malignant Hematology

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CLINICAL TRIAL 20282

A Randomized Phase II/III Trial of De-Intensified Radiation Therapy for Patients with Early-Stage, P16 Positive, Non-Smoking Associated Oropharyngeal Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL 20769

A Phase III, Open-label, Randomized Study of Osimertinib with or without Platinum Plus Pemetrexed Chemotherapy, as First-line Treatment in Patients with Epidermal Growth Factor Receptor (EGFR) Mutation- Positive, Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLAURA2)

Cancer Type: Thoracic

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CLINICAL TRIAL 20615

A Phase 1 Open-Label, Multi-Center First in Human Study of TnMUC1-Targeted Genetically-Modified Chimeric Antigen Receptor T Cells in Patients with Advanced TnMUC1-Positive Solid Tumors and Multiple Myeloma

Cancer Type: Thoracic

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CLINICAL TRIAL 20530

Multicenter, Phase II, Neoadjuvant and Adjuvant Study of Alectinib, Entrectinib, or Vemurafenib Plus Cobimetinib in Patients with Stages I-III Non-Small Cell Lung Cancer with ALK, ROS1, NTRK, or BRAF V600E Molecular Alterations

Cancer Type: Thoracic

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CLINICAL TRIAL 20734

Understanding and Predicting Breast Cancer Events after Treatment (UPBEAT)

Cancer Type: Breast

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