Determining the Structural- and Functional-Level Effects of Diet-specific Interventions on The Gut Microbiota of a Diverse Sample of Southern United States Adults
Specific Aim 1 - Examine the effect of a diet-specific ( DASH or standard American ) 4-week intervention on the gut microbiota of a racially diverse sample of adults and test for race effects
Specific Aim 2 - Evaluate diet-specific effects on functional markers of the gut microbiota including production of secondary bile acids (e.g. lithocholic acid, deoxycholic acid), SCFAs (e.g, acetate, butyrate, propionate), and inflammatory markers (e.g., calprotectin, IL-6) and test for race effects
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