Cancer Type: Cutaneous
Study Type: Treatment
Phase: Phase II
Principal Investigator: Tarhini, Ahmad
A Phase II Study of Binimetinib plus Belinostat for Subjects with Metastatic Uveal Melanoma
This research study is investigating Binimetinib and Belinostat in participants with metastatic uveal melanoma. The research study will test the study drugs to see if the combination of binimetinib and belinostat can make tumors shrink or stop growing.
To evaluate the objective response rate (ORR) utilizing RECIST v.1.1.Progression free survival (PFS), Overall survival (OS), Evaluate safety and toxicity, The banking of tumor and blood biospecimens for the conduct of mechanistic and biomarker studies
Belinostat (); Binimetinib (); PXD101 (Belinostat)
If you are interested in learning more about clinical trials, our clinical trial navigators can discuss your options and recommend opportunities that may be suitable for you. Call 813-745-6100 or 1-800-679-0775 (toll-free) or submit a clinical trials inquiry form.
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