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A Phase II Study of Binimetinib plus Belinostat for Subjects with Metastatic Uveal Melanoma
This research study is investigating Binimetinib and Belinostat in participants with metastatic uveal melanoma. The research study will test the study drugs to see if the combination of binimetinib and belinostat can make tumors shrink or stop growing.
To evaluate the objective response rate (ORR) utilizing RECIST v.1.1.Progression free survival (PFS), Overall survival (OS), Evaluate safety and toxicity, The banking of tumor and blood biospecimens for the conduct of mechanistic and biomarker studies
Belinostat (); Binimetinib (); PXD101 (Belinostat)
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