Neuroendocrine Tumor Treatment

Neuroendocrine tumor treatment strategies are often determined by the tumor’s location and whether it has affected other tissues and organs. These tumors can be found in many places in the body, such as the lungs, brain and gastrointestinal tract, which includes the stomach, intestines and pancreas (neuroendocrine tumors of the pancreas are described as islet cell tumors).

The multispecialty team of treatment experts specializing in neuroendocrine tumors in Moffitt Cancer Center’s Gastrointestinal Oncology Program has an array of options available for treating a patient’s individual condition. These treatment options take into account the patient’s medical history, the tumor’s unique characteristics and other factors. After an extensive consultation and evaluation, a patient’s neuroendocrine tumor team may recommend one or more of the following treatments:

  • Surgery – We offer the latest surgical procedures, which include the resection of tumors that involve blood vessels, as well as minimally invasive procedures and bypass procedures.
  • Chemotherapy – A patient may receive therapeutic drugs orally or by injection in an effort to destroy or slow the growth of the tumor. Our team also performs novel combination chemotherapy and molecular targeted therapy to address these tumors.
  • Radiation therapy – In addition to standard external beam radiation therapy and internal radiation therapy (brachytherapy), we perform stereotactic body radiotherapy and MRO-focused ultrasound treatments as well as other advanced radiation therapies to destroy cancer cells. This treatment option may be used in combination with surgery and/or chemotherapy to prevent recurrence of the cancer.
  • Interventional radiology – The neuroendocrine tumor team offers a variety of innovative treatment techniques, including arterial embolization and radiofrequency ablation, which are designed to block the blood supply to the tumor. We also offer image-directed nonvascular interventions.
  • Lutathera - A form of targeted radiotherapy that is administered intravenously. This treatment uses high doses of radiation to destroy cancer cells while limiting harm to surrounding healthy tissues.

Moffitt’s neuroendocrine tumor team can also provide extensive pain management and supportive care services, to help alleviate chronic and acute discomfort with medications and minimally invasive procedures. Furthermore, our team provides supportive therapies, such as acupuncture, massage therapy and relaxation techniques that can both help to alleviate pain and provide an improved quality of life.

In addition, the neuroendocrine treatment team at Moffitt supports landmark research in finding new medications, surgical procedures, molecular therapies, immunotherapies and endoscopic procedures. This research has helped define us as a cancer center that offers robust clinical trials in individualized medicine, creating targeted treatments that improve patient outcomes, reduce side effects and prevent the recurrence of the condition. Due to our research efforts, Moffitt has been designated as a Comprehensive Cancer Center by the National Cancer Institute – the only center based in Florida to earn this distinction.

At Moffitt Cancer Center, we do not require a referral to consult with a member of our team of oncologists specializing in neuroendocrine tumors. If you’re interested in learning more about our treatment strategies, or if you have any other questions regarding neuroendocrine tumors, call 1-888-663-3488, or fill out our online patient registration form.