Cancer Physiology

The Department of Cancer Physiology, previously known as Cancer Imaging and Metabolism, is focused on the characterization of cancers within their native state. A major focus is the use of non-destructive techniques (imaging and spectroscopy) to monitor cancers and their microenvironments. The data from such studies are quantitatively analyzed and increasingly used to inform mathematical models, in collaboration with the Department of Integrated Mathematical Oncology, to develop new paradigms for carcinogenesis and cancer therapy. 

Examples of research areas include "radiomics" which converts images into mineable data for improved prognosis and prediction, "habitat imaging" which defines the physiology within specific sub-regions of tumors that influences carcinogenesis and therapy response, and “metabolomics” which seeks to identify novel metabolic phenotypes of cancer for illumination of novel therapeutic strategies. This work is being undertaken in human patients as well as in animal models, and there are significant collaborations with Moffitt clinical departments of Radiology, Radiation Oncology and Pathology, inter alia. Cancer Physiology faculty members also actively collaborate with faculty members at other institutions in the US and throughout the world.

Cancer Physiology Department Members 

Department Chair: 
Robert J. Gillies, PhD 

Gina DeNicola, PhD
Robert J. Gillies, PhD
Andriy Marusyk, PhD
David L. Morse, PhD
Natarajan Raghunand, PhD
Ariosto S. Silva, PhD
Haibin Tian, PhD

Joint Appointments:

Jung W. Choi, MD, PhD (Radiology)
Kujtim Latifi, PhD (Radiation Oncology)
Eduardo Moros, PhD (Radiation Oncology)
Jingsong Zhang, MD, PhD (Urological Oncology)
Geoffrey G. Zhang, PhD (Radiation Oncology)