Cancer Type: Head & Neck
Study Type: Treatment
Phase: Phase II
Principal Investigator: Caudell, Jimmy
Keystroke: A Randomized Phase II Study of Pembrolizumab (Keytruda) Plus Stereotactic Re-irradiation versus SBRT Alone For Locoregionally Recurrent or Second Primary Head and Neck Carcinoma
The purpose of the first part of this study is to determine whether adding pembrolizumab (study drug) to radiation (the usual approach for your cancer) is safe and tolerable in patients with head and neck cancer
Primary Objective for Run-In Component To evaluate the safety of the addition of pembrolizumab (anti PD-1 immunotherapy) to re-irradiation with SBRT for patients with recurrent or new second primary head and neck squamous cell carcinoma Primary Objective for Phase II Trial To compare progression-free survival (PFS) for patients with recurrent or new second primary head and neck squamous cell carcinoma with SBRT re-irradiation with or without pembrolizumab
Chemotherapy (NOS); Immunotherapy; Radiotherapy
If you are interested in learning more about clinical trials, our clinical trial navigators can discuss your options and recommend opportunities that may be suitable for you. Call 813-745-6100 or 1-800-679-0775 (toll-free) or submit a clinical trials inquiry form.
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