Myelodysplastic syndromes (MDS) are evaluated using a unique staging system. The results provide physicians with the information they need to determine whether a syndrome is low risk, intermediate risk or high risk, and in turn, which therapies to recommend. At Moffitt Cancer Center, located near Clearwater, Florida, our experienced pathologists and hematology oncologists evaluate the characteristics of MDS – along with several individual aspects of a patient’s case – to determine the most appropriate approach to MDS treatment.
The most commonly used MDS staging system, known as the International Prognostic Scoring System (IPPS), uses the following approach:
- The percentage of blasts (immature cells) in the bone marrow is scored on a scale from 0-2.
- Blood counts are scored as either 0 or 1.
- Chromosomal abnormalities are scored from 0-1.
These numbers are then combined to create a total IPPS score. The risk level increases along with the overall score.
The World Health Organization (WHO) developed a similar MDS staging process that assigns 0, 1, 2 or 3 points to each of the following factors:
- Whether a patient requires blood transfusions
- The type of MDS with which a patient has been diagnosed
- Whether the chromosomes in the patient’s bone marrow are good, intermediate or poor
As with the IPPS system, the WHO MDS staging system assigns lower scores for lower risk syndromes and higher scores for higher risk syndromes.
While risk categories can be used to determine which MDS treatments a patient might require, Moffitt Cancer Center understands that there is no such thing as a “standard” case and that each patient requires a unique treatment plan. Residents of Clearwater and other nearby areas can turn to our team for individualized MDS staging assessments and treatment plans. We are capable of treating even the highest risk myelodysplastic syndromes and offer a comprehensive range of therapies to patients of all ages.
To learn more about MDS staging, call 1-888-663-3488 or submit a new patient registration form online. No referral is needed to request an appointment with our team. We can even help patients from Clearwater, Florida, and other neighboring cities arrange the logistics of their visit.