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Name & Description | Number |
---|---|
Small Molecule Inhibitor: 3-(4-fluorophenyl)-N-phenylbenzamide Small-Molecule Inhibitors of the β-Catenin/BCL9 Protein-Protein Interaction | 22MA004N |
Antibodies: Novel Targeted Nanobodies Against HPV E6/E7 to treat HPV Related Cancers | 21MA047N |
β-Catenin/BCL9: 1-Benzoyl 4-Phenoxypiperidines Small-Molecule Inhibitors of the β-Catenin/BCL9 Protein-Protein Interaction | 21MA023 |
p53: Combination Therapy of Hypothermia and Chemotherapy to Treat Temperature Sensitive p53 Mutant Tumors | 21MA021N |
BRD4 JAK2: Sultam (cyclic sulfonamide) BRD4 JAK2 Inhibitors to Treat Myelofibrosis | 21MA020N |
Novel JAK2 Inhibitor Piperadine Aniline Derivatives of Ruxolitinib to Treat Myelofibrosis | 21MA004N |
TROLLS: Inhibition Of TAp63 Regulated Oncogenic Long Noncoding RNAs (TROLLs) for the Treatment Of Cancer | 20MB056 |
β-Catenin/BCL-9: Acyl sulfonamide-containing Small Molecules that Inhibit the β-catenin/BCL9 Protein-Protein Interaction | 20MB051N |
HPV E1: Novel Use for Aminocoumarins as HPV Helicase E1 Inhibitors to Treat Cancer | 20MB046 |
CMG Helicase: Novel Replicative CMG Helicase Inhibitors (CMGi) to Treat Solid Tumors | 20MB046T2 |
TAF1: Novel TAF1 Inhibitors for the Treatment of Cancer | 20MB037N |
ACK1: Small molecule ACK1 Inhibitors for the Treatment of Castrate Resistant Prostate Cancer | 20MA015N |
CDK12/CDK13: Novel Small Molecule Dual Inhibitors for CDK12/CDK13 for the Treatment of Triple Negative Breast Cancer | 19MB064N |
β-catenin/BCL9: Novel Small Molecules that Inhibit the β-catenin/BCL9 Interaction in Breast Cancer | 19MB055 - VIDEO |
β-catenin/TCF: Small Molecule Peptidomimetic Inhibitors of the Interaction of β-catenin and T-cell Factor | 18MB076 |
Novel BRD4/JAK2 Dual Inhibitor Cancer Therapeutics | 18MB053 |
β-catenin/TCF: Small Molecule Inhibitors of the Interaction of β-catenin and T-cell Factor | 18MA018N |
Ubiquitin Bispecific Antibody: Antibodies that Bring the E3 Ubiquitin Ligase into Close Proximity to Receptors to Induce the Receptor’s Degradation | 17MB056N |
XBP-1: XBP-1 Inhibitor B-I09 for the Treatment of Acute GVHD and Solid Organ Rejection | 17MB051 |
β-catenin/BCL-9: Small Molecules that Inhibit the β-catenin/BCL9 Interaction | 17MA014 |
HDAC, BTK: Method of Using HDAC Inhibitors, Alone or in Combination with BTK Inhibitors, for Treating Chronic Lymphocytic Leukemia (CLL) | 16MA023N |
Aurora/JAK2: Dual JAK2 and Aurora A Kinase Inhibitor for GVHD Prophylaxis | 16MA005N |
Ras: Small Molecules that Inhibit Mutant KRAS | 15MA011 |
Ras/Raf: Stapled Peptides as Inhibitors of Mutant KRAS | 15MA012 |
WEE1: Small Molecule WEE1 Inhibitor (WEIN-159) that Inhibits WEE1 Phosphorylation of H2B but Not Cdc2 to Treat Can | 14MB092 |
HDAC, BTK: Method of Using HDAC Inhibitors, Alone or in Combination with BTK Inhibitors, for Treating Non-Hodgkin’s Lymphoma (NHL) | 14MB086N |
YAP1/OCT4: Small Molecule Inhibitors of the Protein-protein Interaction of YAP1 and OCT4 to Treat Cancer | 14MB075N - VIDEO |
BRD4 JAK2: Novel BRD4/JAK2 Dual Inhibitors as Cancer Therapeutics | 14MB069 |
Anti-Infectives: Novel Symmetrical Marinopyrrole Derivative as a Therapeutic against Resistant Bacterial Strains | 12MB110 |
STAT3: Novel Small Molecule STAT3 Inhibitor for Cancer Treatment | 12MB098 |
IRE-1: Novel Small Molecule Inhibitors of IRE-1 for the Treatment of B-cell Cancer | 12MB089 |
Mcl-1/Bcl-xL: Cyclic, Symmetrical and Asymmetrical Marinopyrroles as Anti-Cancer Agents | 12MA035N |
Proteasome: Non-covalent and Reversible Proteasome Inhibitors with an Oxadiazole-isopropylamide Core | 10MB083 |
FT/GGT: Novel Dual Inhibitor of Farnesyltransferase and Geranylgeranyltransferase-1 as an Anti-Cancer Agentbitor | 10MB048 |
LPAAT: Lysophosphatidic Acid Acyltransferase-Beta Inhibitors to Treat Pancreatic Cancer | 10MA019N |
Mcl-1: Asymmetrical Marinopyrroles as Anti-Cancer Agents | 10MA018N |
pH: Method of Inhibiting Metastasis with Systemic Non-Volatile Buffers to Reduce Intratumoral pH | 09MB048 |
Aurora: Novel Small Molecule Aurora A Kinase Inhibitor as a Cancer Therapeutic | 09MA037 |
Rho Kinase (ROCK) Inhibitors as Anticancer Drugs | 09MA015 |
Topoisomerase II: Small Molecule Inhibitors of Nuclear Export of Topoisomerase II Alpha for Multiple Myeloma Treatment | 08MB014 10MB078 |