TVEC is designed to preferentially lyse tumor cells over normal tissue to release tumor associated antigens, produces GM-CSF to activate dendritic cells, and stimulates T cells to infiltrate the tumor (TILs). TILs in breast cancer are associated with better response to neoadjuvant chemotherapy (NAC). This phase 2 trial hypothesized that intratumoral TVEC may enhance response to NAC. Read More
Dr. Brian Czerniecki, chair of the breast cancer program at Moffitt Cancer Center, connected with our Facebook friends in the Ask The Experts series to answer your questions about the breast cancer vaccine. Read More
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