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Analytic Microscopy - Key Publications Over the Last Five Years

1. Dubovsky JA, Wang D, Powers JJ, Berchmans E, Smith MA, Wright KL, Sotomayor EM, Pinilla-Ibarz JA. Restoring the functional immunogenicity of chronic lymphocytic leukemia using epigenetic modifiers. Leuk Res 2011 Mar; 35: (3) 394-404 PMID: 20863567. PMCID: PMC4458853.IF: 2.351

2. Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner. J Biol Chem 2011 Mar; 286: (11) 9382-9392 PMID: 21148306. PMCID: PMC3059047. IF: 4.573

3. Tafreshi NK, Enkemann SA, Bui MM, Lloyd MC, Abrahams D, Huynh AS, Kim J, Grobmyer SR, Carter WB, Vagner J, Gillies RJ, Morse DL. A mammaglobin-A targeting agent for noninvasive detection of breast cancer metastasis in lymph nodes. Cancer Res 2011 Feb; 71: (3) 1050-1059PMID: 21169406. PMCID: PMC4130564. IF: 9.329

4. Dasgupta P, Rizwani W, Pillai S, Davis R, Banerjee S, Hug K, Lloyd M, Coppola D, Haura E, Chellappan SP. ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors. J Natl Cancer Inst 2011 Feb; 103: (4) 317-333 PMID: 21212384. PMCID: PMC3039728. IF: 12.583

5. Paraiso KH, Xiang Y, Rebecca VW, Abel EV, Chen YA, Munko AC, Wood E, Fedorenko IV, Sondak VK, Anderson AR, Ribas A, Palma MD, Nathanson KL, Koomen JM, Messina JL, Smalley KS. PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression. Cancer Res 2011 Apr; 71: (7) 2750-2760 PMID: 21317224. PMCID: PMC3070772. IF: 9.329

6. Wong PG, Winter SL, Zaika E, Cao TV, Oguz U, Koomen JM, Hamlin JL, Alexandrow MG. Cdc45 limits replicon usage from a low density of preRCs in mammalian cells. PLoS One 2011 Jul; 6: (3) e17533- PMID: 21390258. PMCID: PMC3046982. IF: 3.234

7. Kam Y, Rejniak KA, Anderson AR. Cellular modeling of cancer invasion: integration of in silico and in vitro approaches. J Cell Physiol 2012 Feb; 227: (2) 431-438 PMID: 21465465. PMCID: PMC3687536. IF: 3.839  

8. Balasis ME, Forinash KD, Chen YA, Fulp WJ, Coppola D, Hamilton AD, Cheng JQ, Sebti SM. Combination of farnesyltransferase and Akt inhibitors is synergistic in breast cancer cells and causes significant breast tumor regression in ErbB2 transgenic mice. Clin Cancer Res 2011 May; 17: (9) 2852-2862 PMID: 21536547. PMCID: PMC3156694. IF: 8.722  

9. John JK, Smalley KS. Identification of BRAF mutations in eruptive melanocytic nevi: new insights into melanomagenesis? Expert Rev Anticancer Ther 2011 May; 11: (5) 711-714 PMID: 21554046. PMCID: PMC3119904. IF: 2.249

10. Wang X, Raulji P, Mohapatra SS, Patel R, Hellermann G, Kong X, Vera PL, Meyer-Siegler KL, Coppola D, Mohapatra S. Natriuretic peptide receptor a as a novel target for prostate cancer. Mol Cancer 2011 Sep; 10: 56- PMID: 21586128. PMCID: PMC3121714. IF: 4.257

11. Pillai S, Rizwani W, Li X, Rawal B, Nair S, Schell MJ, Bepler G, Haura E, Coppola D, Chellappan S. ID1 facilitates the growth and metastasis of non-small cell lung cancer in response to nicotinic acetylcholine receptor and epidermal growth factor receptor signaling. Mol Cell Biol 2011 Jul; 31: (14) 3052-3067 PMID: 21606196. PMCID: PMC3133413. IF: 4.777  

12. Fedorenko IV, Paraiso KH, Smalley KS. Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma. Biochem Pharmacol 2011 Aug; 82: (3) 201-209 PMID: 21635872. PMCID: PMC4001781. IF: 5.009  

13. Bui MM, Han G, Acs G, Reed D, Gonzalez RJ, Pasha TL, Zhang PJ. Connexin 43 is a potential prognostic biomarker for ewing sarcoma/primitive neuroectodermal tumor. Sarcoma 2011 Jul; 2011: 971050- PMID: 21647307. PMCID: PMC3103998.

14. Huynh AS, Abrahams DF, Torres MS, Baldwin MK, Gillies RJ, Morse DL. Development of an orthotopic human pancreatic cancer xenograft model using ultrasound guided injection of cells. PLoS One 2011 Sep; 6: (5) e20330- PMID: 21647423. PMCID: PMC3103544. IF: 3.234  

15. Marchion DC, Cottrill HM, Xiong Y, Chen N, Bicaku E, Fulp WJ, Bansal N, Chon HS, Stickles XB, Kamath SG, Hakam A, Li L, Su D, Moreno C, Judson PL, Berchuck A, Wenham RM, Apte SM, Gonzalez-Bosquet J, Bloom GC, Eschrich SA, Sebti S, Chen DT, Lancaster JM. BAD phosphorylation determines ovarian cancer chemosensitivity and patient survival. Clin Cancer Res 2011 Oct; 17: (19) 6356-6366 PMID: 21849418. PMCID: PMC3186862. IF: 8.722

16. Ibrahim Hashim A, Cornnell HH, Coelho Ribeiro Mde L, Abrahams D, Cunningham J, Lloyd M, Martinez GV, Gatenby RA, Gillies RJ. Reduction of metastasis using a non-volatile buffer. Clin Exp Metastas 2011 Dec; 28: (8) 841-849 PMID: 21861189. PMCID: PMC3213349. IF: 3.491

17. Guo JP, Coppola D, Cheng JQ. IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation. J Biol Chem 2011 Oct; 286: (43) 37389-37398 PMID: 21908616. PMCID: PMC3199486.IF: 4.573

18. Peng L, Yuan Z, Ling H, Fukasawa K, Robertson K, Olashaw N, Koomen J, Chen J, Lane WS, Seto E. SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities. Mol Cell Biol 2011 Dec; 31: (23) 4720-4734 PMID: 21947282. PMCID: PMC3232929. IF: 4.777  

19. Emmons MF, Gebhard AW, Nair RR, Baz R, McLaughlin ML, Cress AE, Hazlehurst LA. Acquisition of resistance toward HYD1 correlates with a reduction in cleaved α4 integrin expression and a compromised CAM-DR phenotype. Mol Cancer Ther 2011 Dec; 10: (12) 2257-2266 PMID: 21980133. PMCID: PMC3237739. IF: 5.683

20. Tafreshi NK, Bui MM, Bishop K, Lloyd MC, Enkemann SA, Lopez AS, Abrahams D, Carter WB, Vagner J, Gobmyer SR, Gillies RJ, Morse DL. Noninvasive detection of breast cancer lymph node metastasis using carbonic anhydrases IX and XII targeted imaging probes. Clin Cancer Res2012 Jan; 18: (1) 207-219 PMID: 22016510. PMCID: PMC4130557. IF: 8.722

21. Flach EH, Rebecca VW, Herlyn M, Smalley KS, Anderson AR. Fibroblasts contribute to melanoma tumor growth and drug resistance. Mol Pharm 2011 Dec; 8: (6) 2039-2049 PMID: 22067046. PMCID: PMC3235959. IF: 4.384

22. Kreahling JM, Gemmer JY, Reed D, Letson D, Bui M, Altiok S. MK1775, a selective Wee1 inhibitor, shows single-agent antitumor activity against sarcoma cells. Mol Cancer Ther 2012 Jan; 11: (1) 174-182 PMID: 22084170. PMCID: PMC4545500. IF: 5.683

23. Johnson JL, Pillai S, Pernazza D, Sebti SM, Lawrence NJ, Chellappan SP. Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease. Cancer Res 2012 Jan; 72: (2) 516-526 PMID: 22086850. PMCID: PMC3261351. IF: 9.329

24. Davis R, Pillai S, Lawrence N, Sebti S, Chellappan SP. TNF-α-mediated proliferation of vascular smooth muscle cells involves Raf-1-mediated inactivation of Rb and transcription of E2F1-regulated genes. Cell Cycle 2012 Jan; 11: (1) 109-118 PMID: 22185776. PMCID: PMC3272234. IF: 5.243

25. Mahajan K, Coppola D, Chen YA, Zhu W, Lawrence HR, Lawrence NJ, Mahajan NP. Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Am J Pathol 2012 Apr; 180: (4) 1386-1393 PMID: 22322295. PMCID: PMC3349895. IF: 4.591

26. Guo J, Kim D, Gao J, Kurtyka C, Chen H, Yu C, Wu D, Mittal A, Beg AA, Chellappan SP, Haura EB, Cheng JQ. IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer. Oncogene 2013 Jan; 32: (2) 151-159 PMID: 22330135.PMCID: PMC4109158. IF: 8.459

27. Park S, Kim D, Dan HC, Chen H, Testa JR, Cheng JQ. Identification of Akt interaction protein PHF20/TZP that transcriptionally regulates p53. J Biol Chem 2012 Mar; 287: (14) 11151-11163 PMID: 22334668. PMCID: PMC3322870. IF: 4.573  

28. Paraiso KH, Haarberg HE, Wood E, Rebecca VW, Chen YA, Xiang Y, Ribas A, Lo RS, Weber JS, Sondak VK, John JK, Sarnaik AA, Koomen JM, Smalley KS. The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms. Clin Cancer Res 2012 May; 18: (9) 2502-2514 PMID: 22351686. PMCID: PMC3398738. IF: 8.722

29. Bansal N, Marchion DC, Bicaku E, Xiong Y, Chen N, Stickles XB, Sawah EA, Wenham RM, Apte SM, Gonzalez-Bosquet J, Judson PL, Hakam A, Lancaster JM. BCL2 antagonist of cell death kinases, phosphatases, and ovarian cancer sensitivity to cisplatin. J Gynecol Oncol 2012 Jan; 23: (1) 35-42 PMID: 22355465. PMCID: PMC3280065. IF: 2.494

30. Helm J, Coppola D, Ganapathy V, Lloyd M, Centeno BA, Chen DT, Malafa MP, Park JY. SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma. Pancreas 2012 Aug; 41: (6) 904-909 PMID: 22450368. PMCID: PMC4593304. IF: 2.959

31. McGraw KL, Fuhler GM, Johnson JO, Clark JA, Caceres GC, Sokol L, List AF. Erythropoietin receptor signaling is membrane raft dependent. PLoS One 2012 Aug; 7: (4) e34477- PMID: 22509308. PMCID: PMC3317978. IF: 3.234  

32. Peng L, Ling H, Yuan Z, Fang B, Bloom G, Fukasawa K, Koomen J, Chen J, Lane WS, Seto E. SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60. Mol Cell Biol 2012 Jul; 32: (14) 2823-2836 PMID: 22586264. PMCID: PMC3416197. IF: 4.777

33. Cunningham J, Estrella V, Lloyd M, Gillies R, Frieden BR, Gatenby R. Intracellular electric field and pH optimize protein localization and movement. PLoS One 2012 Sep; 7: (5) e36894- PMID: 22623963. PMCID: PMC3356409. IF: 3.234

34. Ibrahim-Hashim A, Cornnell HH, Abrahams D, Lloyd M, Bui M, Gillies RJ, Gatenby RA. Systemic buffers inhibit carcinogenesis in TRAMP mice. J Urol 2012 Aug; 188: (2) 624-631 PMID: 22704445. PMCID: PMC3694604. IF: 4.471  

35. John JK, Paraiso KH, Rebecca VW, Cantini LP, Abel EV, Pagano N, Meggers E, Mathew R, Krepler C, Izumi V, Fang B, Koomen JM, Messina JL, Herlyn M, Smalley KS. GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation. J Invest Dermatol 2012 Dec; 132: (12) 2818-2827 PMID: 22810307. PMCID: PMC3479306. IF: 7.216  

36. Patel RA, Forinash KD, Pireddu R, Sun Y, Sun N, Martin MP, Schönbrunn E, Lawrence NJ, Sebti SM. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer. Cancer Res 2012 Oct; 72: (19) 5025-5034 PMID: 22846914. PMCID: PMC3463757. IF: 9.329  

37. Xu CX, Xu M, Tan L, Yang H, Permuth-Wey J, Kruk PA, Wenham RM, Nicosia SV, Lancaster JM, Sellers TA, Cheng JQ. MicroRNA miR-214 regulates ovarian cancer cell stemness by targeting p53/Nanog. J Biol Chem 2012 Oct; 287: (42) 34970-34978 PMID: 22927443. PMCID: PMC3471722. IF: 4.573

38. Ramakrishnan R, Huang C, Cho HI, Lloyd M, Johnson J, Ren X, Altiok S, Sullivan D, Weber J, Celis E, Gabrilovich DI. Autophagy induced by conventional chemotherapy mediates tumor cell sensitivity to immunotherapy. Cancer Res 2012 Nov; 72: (21) 5483-5493 PMID: 22942258.PMCID: PMC4577568. IF: 9.329  

39. Singh S, Trevino J, Bora-Singhal N, Coppola D, Haura E, Altiok S, Chellappan SP. EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer. Mol Cancer 2013 Mar; 11: 73- PMID: 23009336. PMCID: PMC3497614. IF: 4.257  

40. Chen L, Chen DT, Kurtyka C, Rawal B, Fulp WJ, Haura EB, Cress WD. Tripartite motif containing 28 (Trim28) can regulate cell proliferation by bridging HDAC1/E2F interactions. J Biol Chem 2012 Nov; 287: (48) 40106-40118 PMID: 23060449. PMCID: PMC3504725. IF: 4.573

41. Gray JE, Altiok S, Alexandrow MG, Walsh FW, Chen J, Schell MJ, Tai DF, Bepler G. Phase 2 randomized study of enzastaurin (LY317615) for lung cancer prevention in former smokers. Cancer 2013 Mar; 119: (5) 1023-1032 PMID: 23065656. PMCID: PMC3578040. IF: 4.889

42. Silva AS, Kam Y, Khin ZP, Minton SE, Gillies RJ, Gatenby RA. Evolutionary approaches to prolong progression-free survival in breast cancer. Cancer Res 2012 Dec; 72: (24) 6362-6370 PMID: 23066036. PMCID: PMC3525750. IF: 9.329

43. Tafreshi NK, Huang X, Moberg VE, Barkey NM, Sondak VK, Tian H, Morse DL, Vagner J. Synthesis and characterization of a melanoma-targeted fluorescence imaging probe by conjugation of a melanocortin 1 receptor (MC1R) specific ligand. Bioconjug Chem 2012 Dec; 23: (12) 2451-2459 PMID: 23116461. PMCID: PMC3563353. IF: 4.513

44. Griner LN, McGraw KL, Johnson JO, List AF, Reuther GW. JAK2-V617F-mediated signaling is dependent on lipid rafts and statins inhibit JAK2-V617F-dependent cell growth. Brit J Haematol 2013 Jan; 160: (2) 177-187 PMID: 23157224. PMCID: PMC4505927. IF: 4.711

45. Xu L, Josan JS, Vagner J, Caplan MR, Hruby VJ, Mash EA, Lynch RM, Morse DL, Gillies RJ. Heterobivalent ligands target cell-surface receptor combinations in vivo. Proc Natl Acad Sci U S A 2012 Dec; 109: (52) 21295-21300 PMID: 23236171. PMCID: PMC3535626. IF: 9.674

46. Estrella V, Chen T, Lloyd M, Wojtkowiak J, Cornnell HH, Ibrahim-Hashim A, Bailey K, Balagurunathan Y, Rothberg JM, Sloane BF, Johnson J, Gatenby RA, Gillies RJ. Acidity generated by the tumor microenvironment drives local invasion. Cancer Res 2013 Mar; 73: (5) 1524-1535PMID: 23288510. PMCID: PMC3594450. IF: 9.329

47. Husain K, Centeno BA, Chen DT, Fulp WJ, Perez M, Zhang Lee G, Luetteke N, Hingorani SR, Sebti SM, Malafa MP. Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E δ-tocotrienol. Carcinogenesis 2013 Apr; 34: (4) 858-863 PMID: 23302291. PMCID: PMC3616675. IF: 5.334

48. Zhang X, Sun Y, Pireddu R, Yang H, Urlam MK, Lawrence HR, Guida WC, Lawrence NJ, Sebti SM. A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation. Cancer Res 2013 Mar; 73: (6) 1922-1933 PMID: 23322008. PMCID: PMC4030628. IF: 9.329

49. Soliman H, Rawal B, Fulp J, Lee JH, Lopez A, Bui MM, Khalil F, Antonia S, Yfantis HG, Lee DH, Dorsey TH, Ambs S. Analysis of indoleamine 2-3 dioxygenase (IDO1) expression in breast cancer tissue by immunohistochemistry. Cancer Immunol Immun 2013 May; 62: (5) 829-837PMID: 23344392. PMCID: PMC4501769. IF: 3.941

50. Youn JI, Kumar V, Collazo M, Nefedova Y, Condamine T, Cheng P, Villagra A, Antonia S, McCaffrey JC, Fishman M, Sarnaik A, Horna P, Sotomayor E, Gabrilovich DI. Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer. Nat Immunol 2013 Mar; 14: (3) 211-220 PMID: 23354483. PMCID: PMC3578019. IF: 20.004  

51. Kong W, He L, Richards EJ, Challa S, Xu CX, Permuth-Wey J, Lancaster JM, Coppola D, Sellers TA, Djeu JY, Cheng JQ. Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer. Oncogene 2014 Feb; 33: (6) 679-689 PMID: 23353819. PMCID: PMC3925335. IF: 8.459  

52. Zheng H, Chen L, Pledger WJ, Fang J, Chen J. p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression. Oncogene 2014 Feb; 33: (6) 734-744 PMID: 23376847. PMCID: PMC3912226. IF: 8.459

53. Hodul PJ, Dong Y, Husain K, Pimiento JM, Chen J, Zhang A, Francois R, Pledger WJ, Coppola D, Sebti SM, Chen DT, Malafa MP. Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism. PLoS One 2013 Aug; 8: (2) e52526- PMID: 23393547. PMCID: PMC3564846. IF: 3.234

54. Singh S, Bora-Singhal N, Kroeger J, Laklai H, Chellappan SP. βArrestin-1 and Mcl-1 modulate self-renewal growth of cancer stem-like side-population cells in non-small cell lung cancer. PLoS One 2013 Aug; 8: (2) e55982- PMID: 23418490. PMCID: PMC3572139. IF: 3.234

55. Marchion DC, Bicaku E, Xiong Y, Zgheib NB, Al Sawah E, Stickles XB, Judson PL, Lopez AS, Cubitt CL, Gonzalez-Bosquet J, Wenham RM, Apte SM, Berglund A, Lancaster JM. A novel c-Met inhibitor, MK8033, synergizes with carboplatin plus paclitaxel to inhibit ovarian cancer cell growth. Oncol Rep 2013 May; 29: (5) 2011-2018 PMID: 23467907. PMCID: PMC4536335. IF: 2.301  

56. Martinez GV, Navath S, Sewda K, Rao V, Foroutan P, Alleti R, Moberg VE, Ahad AM, Coppola D, Lloyd MC, Gillies RJ, Morse DL, Mash EA. Demonstration of a sucrose-derived contrast agent for magnetic resonance imaging of the GI tract. Bioorg Med Chem Lett 2013 Apr; 23: (7) 2061-2064 PMID: 23481651. PMCID: PMC3602218. IF: 2.420  

57. Kreahling JM, Foroutan P, Reed D, Martinez G, Razabdouski T, Bui MM, Raghavan M, Letson D, Gillies RJ, Altiok S. Wee1 inhibition by MK-1775 leads to tumor inhibition and enhances efficacy of gemcitabine in human sarcomas. PLoS One 2013 Sep; 8: (3) e57523- PMID: 23520471.PMCID: PMC3592874. IF: 3.234

58. Haarberg HE, Paraiso KH, Wood E, Rebecca VW, Sondak VK, Koomen JM, Smalley KS. Inhibition of Wee1, AKT, and CDK4 underlies the efficacy of the HSP90 inhibitor XL888 in an in vivo model of NRAS-mutant melanoma. Mol Cancer Ther 2013 Jun; 12: (6) 901-912 PMID: 23538902. PMCID: PMC3683468. IF: 5.683

59. Fu W, Sharma SS, Ma L, Chu B, Bui MM, Reed D, Pledger WJ. Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor. Cell Death Dis 2013 Aug; 4: e566- PMID: 23538447. PMCID: PMC3613821.IF: 5.014

60. Hopewell EL, Zhao W, Fulp WJ, Bronk CC, Lopez AS, Massengill M, Antonia S, Celis E, Haura EB, Enkemann SA, Chen DT, Beg AA. Lung tumor NF-κB signaling promotes T cell-mediated immune surveillance. J Clin Invest 2013 Jun; 123: (6) 2509-2522 PMID: 23635779. PMCID: PMC3668836. IF: 13.215  

61. Rejniak KA, Estrella V, Chen T, Cohen AS, Lloyd MC, Morse DL. The role of tumor tissue architecture in treatment penetration and efficacy: an integrative study. Front Oncol 2013 May; 3: 111- PMID: 23717812. PMCID: PMC3650652.  

62. Song T, Yang L, Kabra N, Chen L, Koomen J, Haura EB, Chen J. The NAD+ synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) regulates ribosomal RNA transcription. J Biol Chem 2013 Jul; 288: (29) 20908-20917 PMID: 23737528. PMCID: PMC3774361.IF: 4.573

63. Tafreshi NK, Silva A, Estrella VC, McCardle TW, Chen T, Jeune-Smith Y, Lloyd MC, Enkemann SA, Smalley KS, Sondak VK, Vagner J, Morse DL. In vivo and in silico pharmacokinetics and biodistribution of a melanocortin receptor 1 targeted agent in preclinical models of melanoma.Mol Pharm 2013 Aug; 10: (8) 3175-3185 PMID: 23763620. PMCID: PMC3785103. IF: 4.384

64. Kim JY, Welsh EA, Oguz U, Fang B, Bai Y, Kinose F, Bronk C, Remsing Rix LL, Beg AA, Rix U, Eschrich SA, Koomen JM, Haura EB. Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells. Proc Natl Acad Sci U S A 2013 Jul; 110: (30) 12414-12419 PMID: 23836654. PMCID: PMC3725062. IF: 9.674

65. Komine H, Kuhn L, Matsushita N, Mulé JJ, Pilon-Thomas S. Examination of MARCO activity on dendritic cell phenotype and function using a gene knockout mouse. PLoS One 2014 Feb; 8: (7) e67795- PMID: 23840879. PMCID: PMC3698187. IF: 3.234

66. Barkey NM, Preihs C, Cornnell HH, Martinez GV, Carie A, Vagner J, Xu L, Lloyd MC, Lynch VM, Hruby VJ, Sessler JL, Sill KN, Gillies RJ, Morse DL. Development and in vivo quantitative magnetic resonance imaging of polymer micelles targeted to the melanocortin 1 receptor. J Med Chem 2013 Aug; 56: (16) 6330-6338 PMID: 23863078. PMCID: PMC3807968. IF: 5.447  

67. Mediavilla-Varela M, Luddy K, Noyes D, Khalil FK, Neuger AM, Soliman H, Antonia S. Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth. Cancer Biol Ther 2013 Sep; 14: (9) 860-868 PMID: 23917542. PMCID: PMC3909555. IF: 3.072

68. Marchion DC, Xiong Y, Chon HS, Sawah EA, Zgheib NB, Ramirez IJ, Abbasi F, Stickles XB, Judson PL, Hakam A, Gonzalez-Bosquet J, Wenham RM, Apte SM, Berglund AE, Lancaster JM. Gene expression data reveal common pathways that characterize the unifocal nature of ovarian cancer. Am J Obstet Gynecol 2013 Dec; 209: (6) 576.e1-576.e16 PMID: 23933223. PMCID: PMC3840156. IF: 4.704  

69. Mailloux AW, Zhang L, Moscinski L, Bennett JM, Yang L, Yoder SJ, Bloom G, Wei C, Wei S, Sokol L, Loughran TP, Epling-Burnette PK. Fibrosis and subsequent cytopenias are associated with basic fibroblast growth factor-deficient pluripotent mesenchymal stromal cells in large granular lymphocyte leukemia. J Immunol 2013 Oct; 191: (7) 3578-3593 PMID: 24014875. PMCID: PMC4346227. IF: 4.922

70. Caceres G, McGraw K, Yip BH, Pellagatti A, Johnson J, Zhang L, Liu K, Zhang LM, Fulp WJ, Lee JH, Al Ali NH, Basiorka A, Smith LJ, Daugherty FJ, Littleton N, Wells RA, Sokol L, Wei S, Komrokji RS, Boultwood J, List AF. TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients. Proc Natl Acad Sci U S A 2013 Oct; 110: (40) 16127-16132 PMID: 24043769. PMCID: PMC3791697. IF: 9.674  

71. Kim E, Rebecca VW, Fedorenko IV, Messina JL, Mathew R, Maria-Engler SS, Basanta D, Smalley KS, Anderson AR. Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach. Cancer Res 2013 Dec; 73: (23) 6874-6885PMID: 24080279. PMCID: PMC3926439. IF: 9.329

72. Trevino JG, Verma M, Singh S, Pillai S, Zhang D, Pernazza D, Sebti SM, Lawrence NJ, Centeno BA, Chellappan SP. Selective disruption of rb-raf-1 kinase interaction inhibits pancreatic adenocarcinoma growth irrespective of gemcitabine sensitivity. Mol Cancer Ther 2013 Dec; 12: (12) 2722-2734 PMID: 24107447. PMCID: PMC3858536. IF: 5.683  

73. Zheng H, Yang L, Peng L, Izumi V, Koomen J, Seto E, Chen J. hMOF acetylation of DBC1/CCAR2 prevents binding and inhibition of SirT1. Mol Cell Biol 2013 Dec; 33: (24) 4960-4970 PMID: 24126058. PMCID: PMC3889553. IF: 4.777  

74. Tafreshi NK, Lloyd MC, Bui MM, Gillies RJ, Morse DL. Carbonic anhydrase IX as an imaging and therapeutic target for tumors and metastases. Subcell Biochem 2013 Sep; 75: 221-254 PMID: 24146382. PMCID: PMC4282494.  

75. Turner JG, Dawson J, Emmons MF, Cubitt CL, Kauffman M, Shacham S, Hazlehurst LA, Sullivan DM. CRM1 Inhibition Sensitizes Drug Resistant Human Myeloma Cells to Topoisomerase II and Proteasome Inhibitors both In Vitro and Ex Vivo. J Cancer 2013 ; 4: (8) 614-625 PMID: 24155773. PMCID: PMC3805989. IF: 3.271  

76. Zheng XQ, Guo JP, Yang H, Kanai M, He LL, Li YY, Koomen JM, Minton S, Gao M, Ren XB, Coppola D, Cheng JQ. Aurora-A is a determinant of tamoxifen sensitivity through phosphorylation of ERα in breast cancer. Oncogene 2014 Oct; 33: (42) 4985-4996 PMID: 24166501. PMCID: PMC4002670. IF: 8.459  

77. Wei S, Chen X, McGraw K, Zhang L, Komrokji R, Clark J, Caceres G, Billingsley D, Sokol L, Lancet J, Fortenbery N, Zhou J, Eksioglu EA, Sallman D, Wang H, Epling-Burnette PK, Djeu J, Sekeres M, Maciejewski JP, List A. Lenalidomide promotes p53 degradation by inhibiting MDM2 auto-ubiquitination in myelodysplastic syndrome with chromosome 5q deletion. Oncogene 2013 Feb; 32: (9) 1110-1120 PMID: 22525275. PMCID: PMC3751397. IF: 8.459

78. Li J, Bennett K, Stukalov A, Fang B, Zhang G, Yoshida T, Okamoto I, Kim JY, Song L, Bai Y, Qian X, Rawal B, Schell M, Grebien F, Winter G, Rix U, Eschrich S, Colinge J, Koomen J, Superti-Furga G, Haura EB. Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms. Mol Syst Biol 2014 Mar; 9: 705- PMID: 24189400. PMCID: PMC4039310. IF: 10.872  

79. Blaskovich MA, Yendluri V, Lawrence HR, Lawrence NJ, Sebti SM, Springett GM. Lysophosphatidic acid acyltransferase beta regulates mTOR signaling. PLoS One 2013 ; 8: (10) e78632- PMID: 24205284. PMCID: PMC3814986. IF: 3.234    

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81. Sun J, He H, Pillai S, Xiong Y, Challa S, Xu L, Chellappan S, Yang S. GATA3 transcription factor abrogates Smad4 transcription factor-mediated fascin overexpression, invadopodium formation, and breast cancer cell invasion. J Biol Chem 2013 Dec; 288: (52) 36971-36982 PMID: 24235142. PMCID: PMC3873555. IF: 4.573

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87. Soliman H, Khalil F, Antonia S. PD-L1 expression is increased in a subset of basal type breast cancer cells. PLoS One 2014 ; 9: (2) e88557- PMID: 24551119. PMCID: PMC3925108. IF: 3.234  

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91. Rebecca VW, Wood ER, Fedorenko IV, Paraiso KH, Haarberg HE, Chen Y, Xiang Y, Sarnaik A, Gibney GT, Sondak VK, Koomen JM, Smalley KS. Evaluating melanoma drug response and therapeutic escape with quantitative proteomics. Mol Cell Proteomics 2014 Jul; 13: (7) 1844-1854PMID: 24760959. PMCID: PMC4083119. IF: 6.564  

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