Volker Mai, PhD, MPH
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Volker Mai, PhD, MPH

Overview

Discipline

    • Center for Infection Research in Cancer
    • Cancer Epidemiology Program

Education & Training

    • Harvard School of Public Health, MPH - Quantitative Methods
    • University of Georgia, PhD - Microbiology
Publications

  • Costea PI, Zeller G, Sunagawa S, Pelletier E, Alberti A, Levenez F, Tramontano M, Driessen M, Hercog R, Jung FE, Kultima JR, Hayward MR, Coelho LP, Allen-Vercoe E, Bertrand L, Blaut M, Brown JRM, Carton T, Cools-Portier S, Daigneault M, Derrien M, Druesne A, de Vos WM, Finlay BB, Flint HJ, Guarner F, Hattori M, Heilig H, Luna RA, van Hylckama Vlieg J, Junick J, Klymiuk I, Langella P, Le Chatelier E, Mai V, Manichanh C, Martin JC, Mery C, Morita H, O'Toole PW, Orvain C, Patil KR, Penders J, Persson S, Pons N, Popova M, Salonen A, Saulnier D, Scott KP, Singh B, Slezak K, Veiga P, Versalovic J, Zhao L, Zoetendal EG, Ehrlich SD, Dore J, Bork P. Towards standards for human fecal sample processing in metagenomic studies. Nat Biotechnol. 2017 Nov;35(11):1069-1076. Pubmedid: 28967887.
  • Burrus RG, Hogsette JA, Kaufman PE, Maruniak JE, Simonne AH, Mai V. Prevalence of Escherichia coli O157:H7 From House Flies (Diptera: Muscidae) and Dairy Samples in North Central Florida1. J Med Entomol. 2017 May;54(3):733-741. Pubmedid: 28025247.
  • Pammi M, Cope J, Tarr PI, Warner BB, Morrow AL, Mai V, Gregory KE, Kroll JS, McMurtry V, Ferris MJ, Engstrand L, Lilja HE, Hollister EB, Versalovic J, Neu J. Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis. Microbiome. 2017 Mar;5(1):31. Pubmedid: 28274256. Pmcid: PMC5343300.
  • Dennis-Wall JC, Culpepper T, Nieves C, Rowe CC, Burns AM, Rusch CT, Federico A, Ukhanova M, Waugh S, Mai V, Christman MC, Langkamp-Henken B. Probiotics (Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, and Bifidobacterium longum MM-2) improve rhinoconjunctivitis-specific quality of life in individuals with seasonal allergies: a double-blind, placebo-controlled, randomized trial. Am J Clin Nutr. 2017 Mar;105(3):758-767. Pubmedid: 28228426.
  • Cai Y, Zheng W, Yao J, Yang Y, Mai V, Mao Q, Sun Y. ESPRIT-Forest: Parallel clustering of massive amplicon sequence data in subquadratic time. PLoS Comput Biol. 2017 Apr;13(4):e1005518. Pubmedid: 28437450. Pmcid: PMC5421816.
  • Roesch LF, Silveira RC, Corso AL, Dobbler PT, Mai V, Rojas BS, Laureano ÁM, Procianoy RS. Diversity and composition of vaginal microbiota of pregnant women at risk for transmitting Group B Streptococcus treated with intrapartum penicillin. PLoS One. 2017;12(2):e0169916. Pubmedid: 28178310. Pmcid: PMC5298327.
  • Burns AM, Zitt MA, Rowe CC, Langkamp-Henken B, Mai V, Nieves C, Ukhanova M, Christman MC, Dahl WJ. Diet quality improves for parents and children when almonds are incorporated into their daily diet: a randomized, crossover study. Nutr Res. 2016 Jan;36(1):80-89. Pubmedid: 26773784.
  • Pinheiro de Oliveira F, Mendes RH, Dobbler PT, Mai V, Pylro VS, Waugh SG, Vairo F, Refosco LF, Roesch LF, Schwartz IV. Phenylketonuria and Gut Microbiota: A Controlled Study Based on Next-Generation Sequencing. PLoS One. 2016;11(6):e0157513. Pubmedid: 27336782. Pmcid: PMC4918959.
  • Mai V, Stine OC. Bowel preparation for colonoscopy: relevant for the gut's microbiota?. Gut. 2015 Oct;64(10):1504-1505. Pubmedid: 25681401.
  • Spaiser SJ, Culpepper T, Nieves C, Ukhanova M, Mai V, Percival SS, Christman MC, Langkamp-Henken B. Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, and Bifidobacterium longum MM-2 Ingestion Induces a Less Inflammatory Cytokine Profile and a Potentially Beneficial Shift in Gut Microbiota in Older Adults: A Randomized, Double-Blind, Placebo-Con. J Am Coll Nutr. 2015 Apr;34(6):459-469. Pubmedid: 25909149.
  • Hickman D, Jones MK, Zhu S, Kirkpatrick E, Ostrov DA, Wang X, Ukhanova M, Sun Y, Mai V, Salemi M, Karst SM. The effect of malnutrition on norovirus infection. MBio. 2014 Mar;5(2):e01032-e01013. Pubmedid: 24595373. Pmcid: PMC3958801.
  • Ukhanova M, Wang X, Baer DJ, Novotny JA, Fredborg M, Mai V. Effects of almond and pistachio consumption on gut microbiota composition in a randomised cross-over human feeding study. Br J Nutr. 2014 Jun;111(12):2146-2152. Pubmedid: 24642201.
  • Baer DJ, Stote KS, Henderson T, Paul DR, Okuma K, Tagami H, Kanahori S, Gordon DT, Rumpler WV, Ukhanova M, Culpepper T, Wang X, Mai V. The metabolizable energy of dietary resistant maltodextrin is variable and alters fecal microbiota composition in adult men. J Nutr. 2014 Jul;144(7):1023-1029. Pubmedid: 24744316.
  • Antharam VC, Li E, Ishmael A, Sharma A, Mai V, Rand KH, Wang GP. Intestinal dysbiosis and depletion of butyrogenic bacteria in Clostridium difficile infection and nosocomial diarrhea. J Clin Microbiol. 2013 Sep;51(9):2884-2892. Pubmedid: 23804381. Pmcid: PMC3754663.
  • Mai V, Morris JG. Need for prospective cohort studies to establish human gut microbiome contributions to disease risk. J Natl Cancer Inst. 2013 Dec;105(24):1850-1851. Pubmedid: 24316594.
  • Torrazza RM, Ukhanova M, Wang X, Sharma R, Hudak ML, Neu J, Mai V. Intestinal microbial ecology and environmental factors affecting necrotizing enterocolitis. PLoS One. 2013;8(12):e83304. Pubmedid: 24386174. Pmcid: PMC3875440.
  • Mai V, Ukhanova M, Visone L, Abuladze T, Sulakvelidze A. Bacteriophage Administration Reduces the Concentration of Listeria monocytogenes in the Gastrointestinal Tract and Its Translocation to Spleen and Liver in Experimentally Infected Mice. Int J Microbiol. 2011 Jul;2010:624234. Pubmedid: 20652074. Pmcid: PMC2905708.
  • Mshvildadze M, Neu J, Shuster J, Theriaque D, Li N, Mai V. Intestinal microbial ecology in premature infants assessed with non-culture-based techniques. J Pediatr. 2010 Jan;156(1):20-25. Pubmedid: 19783002. Pmcid: PMC3628625.
  • Mai V, McCrary QM, Sinha R, Glei M. Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers. Nutr J. 2009 Oct;8:49. Pubmedid: 19845958. Pmcid: PMC2773807.
  • Young C, Sharma R, Handfield M, Mai V, Neu J. Biomarkers for infants at risk for necrotizing enterocolitis: clues to prevention?. Pediatr Res. 2009 May;65(5 Pt 2):91R-97R. Pubmedid: 19190533. Pmcid: PMC2929681.
  • Mai V, Draganov PV. Recent advances and remaining gaps in our knowledge of associations between gut microbiota and human health. World J Gastroenterol. 2009 Jan;15(1):81-85. Pubmedid: 19115471. Pmcid: PMC2653298.
  • Neu J, Mshvildadze M, Mai V. A roadmap for understanding and preventing necrotizing enterocolitis. Curr Gastroenterol Rep. 2008 Oct;10(5):450-457. Pubmedid: 18799119.
  • Flood A, Mai V, Pfeiffer R, Kahle L, Rosen CJ, Lanza E, Schatzkin A. Serum concentrations of insulin-like growth factor and insulin-like growth factor binding protein 3 and recurrent colorectal adenomas. Cancer Epidemiol Biomarkers Prev. 2008 Jun;17(6):1493-1498. Pubmedid: 18559566. Pmcid: PMC2597396.
  • Lunn J, Kuhnle G, Mai V, Frankenfeld C, Shuker D, Glen R, Goodman J, Pollock J, Bingham S. The effect of haem in red and processed meat on the endogenous formation of N-nitroso compounds in the upper gastrointestinal tract. Carcinogenesis. 2007 Mar;28(3):685-690. Pubmedid: 17052997.
  • Mai V, Colbert L, Perkins S, Schatzkin A, Hursting S. Intestinal microbiota: a potential diet-responsive prevention target in ApcMin mice. Mol Carcinogen. 2007 Jan;46(1):42-48. Pubmedid: 16929480.
  • Colbert L, Mai V, Tooze J, Perkins S, Berrigan D, Hursting S. Negative energy balance induced by voluntary wheel running inhibits polyp development in APCMin mice. Carcinogenesis. 2006 Oct;27(10):2103-2107. Pubmedid: 16699175.
  • Trachtman H, Christen E, Cnaan A, Patrick J, Mai V, Mishra J, Jain A, Bullington N, Devarajan P. Urinary neutrophil gelatinase-associated lipocalcin in D+HUS: a novel marker of renal injury. Pediatr Nephrol. 2006 Jul;21(7):989-994. Pubmedid: 16773412.
  • Cornick NA, Helgerson AF, Mai V, Ritchie JM, Acheson DW. In vivo transduction of an Stx-encoding phage in ruminants. Appl Environ Microbiol. 2006 Jul;72(7):5086-5088. Pubmedid: 16820511.
  • Mai V, Greenwald B, Morris JG J, Raufman J, Stine O. Effect of bowel preparation and colonoscopy on post-procedure intestinal microbiota composition. Gut. 2006 Dec;55(12):1822-1823. Pubmedid: 17124165.
  • Mai V, Braden CR, Heckendorf J, Pironis B, Hirshon JM. Monitoring of stool microbiota in subjects with diarrhea indicates distortions in composition. J Clin Microbiol. 2006 Dec;44(12):4550-4552. Pubmedid: 17021054. Pmcid: PMC1698375.
  • Nataro J, Mai V, Johnson J, Blackwelder W, Heimer R, Tirrell S, Edberg S, Braden C, Glenn Morris J J, Hirshon J. Diarrheagenic Escherichia coli infection in Baltimore, Maryland, and New Haven, Connecticut. Clin Infect Dis. 2006 Aug;43(4):402-407. Pubmedid: 16838226.
  • Mai V, Kant A, Flood A, Lacey JV J, Schairer C, Schatzkin A. Diet quality and subsequent cancer incidence and mortality in a prospective cohort of women. Int J Epidemiol. 2005 Feb;34(1):54-60. Pubmedid: 15649959.
  • Mai V. Dietary modification of the intestinal microbiota. Nutr Rev. 2004 Jun;62(6 Pt 1):235-242. Pubmedid: 15291396.
  • Mai V, Katki H, Harmsen H, Gallaher D, Schatzkin A, Baer D, Clevidence B. Effects of a controlled diet and black tea drinking on the fecal microflora composition and the fecal bile acid profile of human volunteers in a double-blinded randomized feeding study. J Nutr. 2004 Feb;134(2):473-478. Pubmedid: 14747691.
  • Mai V, Morris JG J. Colonic bacterial flora: changing understandings in the molecular age. J Nutr. 2004 Feb;134(2):459-464. Pubmedid: 14747689.
  • Colbert L, Mai V, Perkins S, Berrigan D, Lavigne J, Wimbrow H, Alvord W, Haines D, Srinivas P, Hursting S. Exercise and intestinal polyp development in APCMin mice. Med Sci Sports Exerc. 2003 Oct;35(10):1662-1669. Pubmedid: 14523302.
  • Mai V, Colbert L, Berrigan D, Perkins S, Pfeiffer R, Lavigne J, Lanza E, Haines D, Schatzkin A, Hursting S. Calorie restriction and diet composition modulate spontaneous intestinal tumorigenesis in Apc(Min) mice through different mechanisms. Cancer Res. 2003 Apr;63(8):1752-1755. Pubmedid: 12702556.
  • Mai V, Flood A, Peters U, Lacey JV J, Schairer C, Schatzkin A. Dietary fibre and risk of colorectal cancer in the Breast Cancer Detection Demonstration Project (BCDDP) follow-up cohort. Int J Epidemiol. 2003 Apr;32(2):234-239. Pubmedid: 12714542.
  • Mai V, Wiegel J. Advances in development of a genetic system for Thermoanaerobacterium spp.: expression of genes encoding hydrolytic enzymes, development of a second shuttle vector, and integration of genes into the chromosome. Appl Environ Microbiol. 2000 Nov;66(11):4817-4821. Pubmedid: 11055929.
  • Mai V, Wiegel J, Lorenz W. Cloning, sequencing, and characterization of the bifunctional xylosidase-arabinosidase from the anaerobic thermophile thermo anaerobacterethanolicus. Gene. 2000 Apr;247(1-2):137-143. Pubmedid: 10773453.
  • Engle M, Li Y, Rainey F, DeBlois S, Mai V, Reichert A, Mayer F, Messner P, Wiegel J. Thermobrachium celere gen. nov., sp. nov., a rapidly growing thermophilic, alkali tolerant, and proteolytic obligate anaerobe. Int J Syst Bacteriol. 1996 Oct;46(4):1025-1033. Pubmedid: 8863432 .
  • Mai V, Ukhanova M, Reinhard MK, Li M, Sulakvelidze A. Bacteriophage administration significantly reduces Shigella colonization and shedding by Shigella-challenged mice without deleterious side effects and distortions in the gut microbiota. Bacteriophage. 5(4):e1088124. Pubmedid: 26909243. Pmcid: PMC4745833.