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Tomar Ghansah, PhD

Research Program: Immuno-Oncology Program

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  • Overview

    Associations

    • Immuno-Oncology Program

    Education & Training

    Graduate:

    • Meharry Medical College, PhD - Microbiology

    Fellowship:

    • H. Lee Moffitt Cancer Center & Research Institute - Immunology
  • Publications

    • Husain K, Williamson TT, Nelson N, Ghansah T. Protein kinase 2 (CK2): a potential regulator of immune cell development and function in cancer. Immunol Med. 2021 Sep.44(3):159-174. Pubmedid: 33164702.
    • Villalobos-Ayala K, Ortiz Rivera I, Alvarez C, Husain K, DeLoach D, Krystal G, Hibbs ML, Jiang K, Ghansah T. Apigenin Increases SHIP-1 Expression, Promotes Tumoricidal Macrophages and Anti-Tumor Immune Responses in Murine Pancreatic Cancer. Cancers (Basel). 2020 Dec.12(12). Pubmedid: 33291556. Pmcid: PMC7761852.
    • Gonzalez VJ, Abbas-Aghababazadeh F, Fridley BL, Ghansah T, Saligan LN. Expression of Sestrin Genes in Radiotherapy for Prostate Cancer and Its Association With Fatigue: A Proof-of-Concept Study. Biol Res Nurs. 2018 Mar.20(2):218-226. Pubmedid: 29325451. Pmcid: PMC5824984.
    • Nelson N, Szekeres K, Iclozan C, Rivera IO, McGill A, Johnson G, Nwogu O, Ghansah T. Apigenin: Selective CK2 inhibitor increases Ikaros expression and improves T cell homeostasis and function in murine pancreatic cancer. PLoS One. 2017.12(2):e0170197. Pubmedid: 28152014. Pmcid: PMC5289423.
    • Nelson N, Xiang S, Zhang X, Gilvary D, Djeu J, Husain K, Malafa M, Vohra N, Pilon-Thomas S, Ghansah T. Murine pancreatic adenocarcinoma reduces Ikaros expression and disrupts T cell homeostasis. PLoS One. 2015 Jan.10(1):e0115546. Pubmedid: 25629611. Pmcid: PMC4309586.
    • Watson JE, Patel NA, Carter G, Moor A, Patel R, Ghansah T, Mathur A, Murr MM, Bickford P, Gould LJ, Cooper DR. Comparison of Markers and Functional Attributes of Human Adipose-Derived Stem Cells and Dedifferentiated Adipocyte Cells from Subcutaneous Fat of an Obese Diabetic Donor. Adv Wound Care (New Rochelle). 2014 Mar.3(3):219-228. Pubmedid: 24669358. Pmcid: PMC3955970.
    • Ghansah T, Vohra N, Kinney K, Weber A, Kodumudi K, Springett G, Sarnaik AA, Pilon-Thomas S. Dendritic cell immunotherapy combined with gemcitabine chemotherapy enhances survival in a murine model of pancreatic carcinoma. Cancer Immunol Immun. 2013 Jun.62(6):1083-1091. Pubmedid: 23604104. Pmcid: PMC3666559.
    • Ghansah T. A novel strategy for modulation of MDSC to enhance cancer immunotherapy. Oncoimmunology. 2012 Sep.1(6):984-985. Pubmedid: 23162780. Pmcid: PMC3489768.
    • Jiang K, Apostolatos AH, Ghansah T, Watson JE, Vickers T, Cooper DR, Epling-Burnette PK, Patel NA. Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdeltaVIII in NT2 cells. Biochemistry-Us. 2008 Jan.47(2):787-797. Pubmedid: 18092819.
    • Paraiso K, Ghansah T, Costello A, Engelman R, Kerr W. Induced SHIP deficiency expands myeloid regulatory cells and abrogates graft-versus-host disease. J Immunol. 2007 Mar.178(5):2893-2900. Pubmedid: 17312133.
    • Ghansah T, Paraiso K, Highfill S, Desponts C, May S, McIntosh J, Wang J, Ninos J, Brayer J, Cheng F, Sotomayor E, Kerr W. Expansion of myeloid suppressor cells in SHIP-deficient mice represses allogeneic T cell responses. J Immunol. 2004 Dec.173(12):7324-7330. Pubmedid: 15585856.
    • Cheng F, Wang H, Cuenca A, Huang M, Ghansah T, Brayer J, Kerr W, TakedaK, Akira S, Schoenberger S, Yu H, Jove R, Sotomayor E. A critical role for Stat3 signaling in immune tolerance. Immunity. 2003 Sep.19(3):425-436. Pubmedid: 14499117.
    • Wang J, Howson J, Ghansah T, Desponts C, Ninos J, May S, Nguyen K, Toyama-Sorimachi N, Kerr W. Influence of SHIP on the NK repertoire and allogeneic bone marrow transplantation. Science. 2002 Mar.295(5562):2094-2097. Pubmedid: 11896280.
    • Wang JW, Howson J, Ghansah T, Ninos J, Kerr WG. Inhibition of Apoptosis by the BEACH Domain and WD Repeats of Gene that has Key Features of Both Protein Kinase A Anchor and Genes. ScientificWorldJournal. 2001 Oct.1:96. Pubmedid: 30147573. Pmcid: PMC6084247.
    • Tu Z, Ninos J, Ma Z, Wang J, Lemos M, Desponts C, Ghansah T, Howson J, Kerr W. Embryonic and hematopoietic stem cells express a novel SH2-containing inositol 5'-phosphatase isoform that partners with the Grb2 adapter protein. Blood. 2001 Oct.98(7):2028-2038. Pubmedid: 11567986.
    • Ghansah T, Ager E, Freeman-Junior P, Villalta F, Lima M. Epidermal growth factor binds to a receptor on Trypanosoma cruzi amastigotes inducing signal transduction events and cell proliferation. J Eukaryot Microbiol. 49(5):383-390. Pubmedid: 12425525.
    • Ghansah T, Ninos M, Kerr A. Role for the SH2 containing insitol phosphatase in the biology of natural killer cells and stem cells. In: Cooper M, Takai J, eds. Activating and inhibitory immunoglobulin-like receptors. Tokoya. Springer-Verlag; 2001;129-139.

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