Marcus Cooke, PhD

Associations

• Cancer Biology & Evolution Program

• Hu CW, Chang YJ, Chang WH, Cooke MS, Chen YR, Chao MR. A Novel Adductomics Workflow Incorporating FeatureHunter Software: Rapid Detection of Nucleic Acid Modifications for Studying the Exposome. Environ Sci Technol. 2024 Jan.58(1):75-89. Pubmedid: 38153287.
• Cooke MS, Hu CW, Chao MR, Chang YJ, Rhodes LE, Evans MD. Letter to the Editor regarding "DNA photoproducts released by repair in biological fluids as biomarkers of the genotoxicity of UV radiation". Anal Bioanal Chem. 2023 Jan.415(3):517-519. Pubmedid: 36376715.
• Muthukumaran RB, Bhattacharjee P, Bhowmick P, Zote L, Malsawmtluangi, Kumar NS, Jahau L, Cooke MS, Hu CW, Chao MR. Genetic and epigenetic instability induced by betel quid associated chemicals. Toxicol Rep. 2023 Feb.10:223-234. Pubmedid: 36845258. Pmcid: PMC9945799.
• Amente S, Scala G, Majello B, Azmoun S, Tempest HG, Premi S, Cooke MS. Genome-wide mapping of genomic DNA damage: methods and implications. Cell Mol Life Sci. 2021 Nov.78(21-22):6745-6762. Pubmedid: 34463773. Pmcid: PMC8558167.
• Burke SL, Cobb J, Agarwal R, Maddux M, Cooke MS. How Robust is the Evidence for a Role of Oxidative Stress in Autism Spectrum Disorders and Intellectual Disabilities?. J Autism Dev Disord. 2021 May.51(5):1428-1445. Pubmedid: 32929662. Pmcid: PMC8084796.
• Chao MR, Evans MD, Hu CW, Ji Y, Møller P, Rossner P, Cooke MS. Biomarkers of nucleic acid oxidation - A summary state-of-the-art. Redox Biol. 2021 Jun.42:101872. Pubmedid: 33579665. Pmcid: PMC8113048.
• Chang YJ, Cooke MS, Chen YR, Yang SF, Li PS, Hu CW, Chao MR. Is high resolution a strict requirement for mass spectrometry-based cellular DNA adductomics?. Chemosphere. 2021 Jul.274:129991. Pubmedid: 33979922. Pmcid: PMC8119933.
• Gorini F, Scala G, Cooke MS, Majello B, Amente S. Towards a comprehensive view of 8-oxo-7,8-dihydro-2'-deoxyguanosine: Highlighting the intertwined roles of DNA damage and epigenetics in genomic instability. DNA Repair (Amst). 2021 Jan.97:103027. Pubmedid: 33285475. Pmcid: PMC7926032.
• Shih YM, Chang YJ, Cooke MS, Pan CH, Hu CH, Chao MR, Hu CW. Alkylating and oxidative stresses in smoking and non-smoking patients with COPD: Implications for lung carcinogenesis. Free Radical Bio Med. 2021 Feb.164:99-106. Pubmedid: 33418114. Pmcid: PMC7897309.
• Shih BB, Farrar MD, Vail A, Allan D, Chao MR, Hu CW, Jones GDD, Cooke MS, Rhodes LE. Influence of skin melanisation and ultraviolet radiation on biomarkers of systemic oxidative stress. Free Radical Bio Med. 2020 Nov.160:40-46. Pubmedid: 32768566. Pmcid: PMC7938299.
• Møller P, Azqueta A, Boutet-Robinet E, Koppen G, Bonassi S, Milić M, Gajski G, Costa S, Teixeira JP, Costa Pereira C, Dusinska M, Godschalk R, Brunborg G, Gutzkow KB, Giovannelli L, Cooke MS, Richling E, Laffon B, Valdiglesias V, Basaran N, Del Bo' C, Zegura B, Novak M, Stopper H, Vodicka P, Vodenkova S, de Andrade VM, Sramkova M, Gabelova A, Collins A, Langie SAS. Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results. Nat Protoc. 2020 Dec.15(12):3817-3826. Pubmedid: 33106678. Pmcid: PMC7688437.
• Guo J, Turesky RJ, Tarifa A, DeCaprio AP, Cooke MS, Walmsley SJ, Villalta PW. Development of a DNA Adductome Mass Spectral Database. Chem Res Toxicol. 2020 Apr.33(4):852-854. Pubmedid: 32223224. Pmcid: PMC7197645.
• Ji Y, Karbaschi M, Cooke MS. Mycoplasma infection of cultured cells induces oxidative stress and attenuates cellular base excision repair activity. Mutat Res Genet Toxicol Environ Mutagen. 2019 Sep.845:403054. Pubmedid: 31561888. Pmcid: PMC6768088.
• Alhegaili AS, Ji Y, Sylvius N, Blades MJ, Karbaschi M, Tempest HG, Jones GDD, Cooke MS. Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes. Int J Mol Sci. 2019 Oct.20(20). Pubmedid: 31618917. Pmcid: PMC6834194.
• Cooke MS, Hu CW, Chao MR. Editorial: Mass Spectrometry for Adductomic Analysis. Front Chem. 2019 Nov.7:794. Pubmedid: 31824925. Pmcid: PMC6881476.
• Samaranayake GJ, Troccoli CI, Zhang L, Huynh M, Jayaraj CJ, Ji D, McPherson L, Onishi Y, Nguyen DM, Robbins DJ, Karbaschi M, Cooke MS, Barrientos A, Kool ET, Rai P. The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors. Mol Cancer Ther. 2019 Nov.19(2):432-446. Pubmedid: 31744893. Pmcid: PMC7079300.
• Tenenbaum R, Agarwal R, Cooke MS, Agrawal MM, Maddux M, Burke SL. Utilization of Complementary and Alternative Therapies in Youth with Developmental Disabilities. Evid Based Complement Alternat Med. 2019 Jun.2019:3630509. Pubmedid: 31341491. Pmcid: PMC6614975.
• Shih YM, Cooke MS, Pan CH, Chao MR, Hu CW. Clinical relevance of guanine-derived urinary biomarkers of oxidative stress, determined by LC-MS/MS. Redox Biol. 2019 Jan.20:556-565. Pubmedid: 30508700. Pmcid: PMC6279954.
• Karbaschi M, Ji Y, Abdulwahed AMS, Alohaly A, Bedoya JF, Burke SL, Boulos TM, Tempest HG, Cooke MS. Evaluation of the Major Steps in the Conventional Protocol for the Alkaline Comet Assay. Int J Mol Sci. 2019 Dec.20(23). Pubmedid: 31810189. Pmcid: PMC6929057.
• Hu CW, Chang YJ, Cooke MS, Chao MR. DNA Crosslinkomics: A Tool for the Comprehensive Assessment of Interstrand Crosslinks Using High Resolution Mass Spectrometry. Anal Chem. 2019 Dec.91(23):15193-15203. Pubmedid: 31670503. Pmcid: PMC6891145.
• Hu CW, Cooke MS, Chang YJ, Chao MR. Direct-acting DNA ethylating agents associated with tobacco use primarily originate from the tobacco itself, not combustion. J Hazard Mater. 2018 Sep.358:397-404. Pubmedid: 30005251.
• Shih BB, Farrar MD, Cooke MS, Osman J, Langton AK, Kift R, Webb AR, Berry JL, Watson REB, Vail A, de Gruijl FR, Rhodes LE. Fractional Sunburn Threshold UVR Doses Generate Equivalent Vitamin D and DNA Damage in Skin Types I-VI but with Epidermal DNA Damage Gradient Correlated to Skin Darkness. J Invest Dermatol. 2018 Oct.138(10):2244-2252. Pubmedid: 29730334. Pmcid: PMC6158343.
• Chao MR, Cooke MS, Kuo CY, Pan CH, Liu HH, Yang HJ, Chen SC, Chiang YC, Hu CW. Children are particularly vulnerable to environmental tobacco smoke exposure: Evidence from biomarkers of tobacco-specific nitrosamines, and oxidative stress. Environ Int. 2018 Nov.120:238-245. Pubmedid: 30103123.
• Delinasios GJ, Karbaschi M, Cooke MS, Young AR. Author Correction: Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes. Sci Rep. 2018 Mar.8(1):4998. Pubmedid: 29555945. Pmcid: PMC5859295.
• Cooke MS. Mycosporine-like amino acids: does Nature make a better sunscreen?. Br J Dermatol. 2018 Jun.178(6):1239-1240. Pubmedid: 29897128.
• Kim G, Karbaschi M, Cooke M, Gaitas A. Light-based methods for whole blood bacterial inactivation enabled by a recirculating flow system. Photochem Photobiol. 2018 Jul.94(4):744-751. Pubmedid: 29418006. Pmcid: PMC6136252.
• Delinasios GJ, Karbaschi M, Cooke MS, Young AR. Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes. Sci Rep. 2018 Jan.8(1):423. Pubmedid: 29323251. Pmcid: PMC5764969.
• Olinski R, Gackowski D, Cooke MS. Endogenously generated DNA nucleobase modifications source, and significance as possible biomarkers of malignant transformation risk, and role in anticancer therapy. BBA. Reviews on cancer. 2018 Jan.1869(1):29-41. Pubmedid: 29128527.
• Cooke MS, Hu CW, Chang YJ, Chao MR. Urinary DNA adductomics - A novel approach for exposomics. Environ Int. 2018 Dec.121(Pt 2):1033-1038. Pubmedid: 30392940. Pmcid: PMC6279464.
• Chang YJ, Cooke MS, Hu CW, Chao MR. Novel approach to integrated DNA adductomics for the assessment of in vitro and in vivo environmental exposures. Arch Toxicol. 2018 Aug.92(8):2665-2680. Pubmedid: 29943112.