M. Catherine Lee
Researcher

M. Catherine Lee

Academic Rank: Assistant Member

Overview

Discipline

    • Breast Oncology
    • Cancer Epidemiology Program

Education & Training

    • Lenox Hill Hospital, Resident - General Surgery
    • Northeastern Ohio Universities College of Medicine, MD
    • Lenox Hill Hospital, Chief Resident - General Surgery
    • University of Michigan Cancer Center, Fellow - Surgical Breast Oncology
Research

In addition to retrospective studies, Dr. Lee is currently co-investigator on a recently funded R21 with Dr. Susan Vadaparampil which seeks to improve genetic counseling services for patients recently diagnosed with breast cancer. She also is actively involved with her colleagues in investigating and improving fertility preservation education for providers and patients; these efforts have resulted in accepted abstracts to the ASCO 2012 National Meeting and the American Society for Reproductive Medicine. She also is collaborating with the faculty in Molecular and Functional Imaging in the development of novel agents for intraoperative identification of breast cancer. And finally, she is the primary investigator for two ongoing clinical trials, one investigator-initiated project examining 3D ultrasound for breast cancer patients, and another industry-sponsored  phase 0 trial examining novel agents in breast cancer. Her other research focus is primarily translational; she has had one grant-funded project examining early biomarkers for breast cancer and continues to actively seek external funding for this and other translational projects.

Publications

  • Dossett LA, Hudson JN, Morris AM, Lee MC, Roetzheim RG, Fetters MD, Quinn GP. The primary care provider (PCP)-cancer specialist relationship: A systematic review and mixed-methods meta-synthesis. CA-Cancer J Clin. 2017 Mar;67(2):156-169. Pubmedid: 27727446. Pmcid: PMC5342924.
  • Mattingly AE, Mooney B, Lin HY, Kiluk JV, Khakpour N, Hoover SJ, Laronga C, Lee MC. Magnetic Resonance Imaging for Axillary Breast Cancer Metastasis in the Neoadjuvant Setting: A Prospective Study. Clin Breast Cancer. 2017 Jun;17(3):180-187. Pubmedid: 27956116.
  • Collins M, O'Donoghue C, Sun W, Zhou JM, Ma Z, Laronga C, Lee MC. Use of axillary lymph node dissection (ALND) in patients with micrometastatic breast cancer. J Surg Res. 2017 Jul;215:55-59. Pubmedid: 28688661.
  • Collins M, O'Donoghue C, Sun W, Zhou JM, Ma Z, Laronga C, Lee MC. Use of axillary lymph node dissection (ALND) in patients with micrometastatic breast cancer. J Surg Res. 2017 Jul;215:55-59. Pubmedid: 28688661 .
  • Nocera NF, Lee MC, Czerniecki BJ. Boosting anti-HER2 CD4 T-helper responses in HER2 expressing ductal carcinoma in situ. Future Oncol. 2017 Jul;13(17):1459-1462. Pubmedid: 28766964.
  • Mellon EA, Orman A, Joya LE, Montejo ME, Laronga C, Hoover SJ, Lee MC, Khakpour N, Kubal PF, Diaz R. Frequency of whole breast radiation therapy after intraoperative radiation therapy due to criteria identified by lumpectomy. Brachytherapy. 2017 Jul;16(1):174-180. Pubmedid: 27816540.
  • González SJ, Mooney B, Lin HY, Zhao X, Kiluk JV, Khakpour N, Laronga C, Lee MC. 2-D and 3-D Ultrasound for Tumor Volume Analysis: A Prospective Study. Ultrasound Med Biol. 2017 Apr;43(4):775-781. Pubmedid: 28187928.
  • Mattingly AE, Kiluk JV, Lee MC. Clinical Considerations of Risk, Incidence, and Outcomes of Breast Cancer in Sexual Minorities. Cancer Control. 2016 Oct;23(4):373-382. Pubmedid: 27842326.
  • Dossett LA, Lowe J, Sun W, Lee MC, Smith PD, Jacobsen PB, Laronga C. Prospective evaluation of skin and nipple-areola sensation and patient satisfaction after nipple-sparing mastectomy. J Surg Oncol. 2016 Jul;114(1):11-16. Pubmedid: 27087574.
  • Nocera NF, Lee MC, De La Cruz LM, Rosemblit C, Czerniecki BJ. Restoring Lost Anti-HER-2 Th1 Immunity in Breast Cancer: A Crucial Role for Th1 Cytokines in Therapy and Prevention. Front Pharmacol. 2016;7:356. Pubmedid: 27766079. Pmcid: PMC5052279.
  • Lee MC, Gonzalez SJ, Lin H, Zhao X, Kiluk JV, Laronga C, Mooney B. Prospective trial of breast MRI versus 2D and 3D ultrasound for evaluation of response to neoadjuvant chemotherapy. Ann Surg Oncol. 2015 Sep;22(9):2888-2894. Pubmedid: 25589151.
  • Jacobsen PB, Lee M. Integrating Psychosocial Care Into Routine Cancer Care. Cancer Control. 2015 Oct;22(4):442-449. Pubmedid: 26678971.
  • Snow R, Reyna C, Johns C, Lee MC, Sun W, Fulp WJ, Kiluk JV, Laronga C. Outcomes with and without axillary node dissection for node-positive lumpectomy and mastectomy patients. Am J Surg. 2015 Oct;210(4):685-693. Pubmedid: 26210706.
  • Quinn GP, Block RG, Clayman ML, Kelvin J, Arvey SR, Lee JH, Reinecke J, Sehovic I, Jacobsen PB, Reed D, Gonzalez L, Vadaparampil ST, Laronga C, Lee MC, Pow-Sang J, Eggly S, Franklin A, Shah B, Fulp WJ, Hayes-Lattin B. If you did not document it, it did not happen: rates of documentation of discussion of infertility risk in adolescent and young adult oncology patients' medical records. J Oncol Pract. 2015 Mar;11(2):137-144. Pubmedid: 25549654. Pmcid: PMC4799849.
  • Acs G, Khakpour N, Kiluk J, Lee MC, Laronga C. The presence of extensive retraction clefts in invasive breast carcinomas correlates with lymphatic invasion and nodal metastasis and predicts poor outcome: a prospective validation study of 2742 consecutive cases. Am J Surg Pathol. 2015 Mar;39(3):325-337. Pubmedid: 25353283.
  • Roetzheim RG, Lee JH, Fulp W, Matos Gomez E, Clayton E, Tollin S, Khakpour N, Laronga C, Lee MC, Kiluk JV. Acceptance and adherence to chemoprevention among women at increased risk of breast cancer. Breast. 2015 Feb;24(1):51-56. Pubmedid: 25491191. Pmcid: PMC4503358.
  • Agostinho JL, Zhao X, Sun W, Laronga C, Kiluk JV, Chen DT, Lee MC. Prediction of positive margins following breast conserving surgery. Breast. 2015 Feb;24(1):46-50. Pubmedid: 25466503.
  • Patel BK, Jafarian N, Abbott AM, Khazai L, Lee MC. Imaging Findings and Management of Primary Breast Cancer in Accessory Axillary Breast Tissue. Clin Breast Cancer. 2015 Aug;15(4):e223-e229. Pubmedid: 25986957.
  • Goble RN, Drukteinis JS, Lee MC, Khakpour N, Kiluk JV, Laronga C. Early experience with ultrasound features after intrabeam intraoperative radiation for early stage breast cancer. J Surg Oncol. 2014 Jun;109(8):751-755. Pubmedid: 24862923.
  • Kiluk JV, Prowler V, Lee MC, Khakpour N, Laronga C, Cox CE. Contralateral axillary nodal involvement from invasive breast cancer. Breast. 2014 Jun;23(3):291-294. Pubmedid: 24709584.
  • Lee MC, Laronga C. The pregnant breast cancer patient: are we failing our most vulnerable population?. Ann Surg Oncol. 2014 Aug;21(8):2474-2475. Pubmedid: 24743913.
  • Prowler VL, Joh JE, Acs G, Kiluk JV, Laronga C, Khakpour N, Lee MC. Surgical excision of pure flat epithelial atypia identified on core needle breast biopsy. Breast. 2014 Aug;23(4):352-356. Pubmedid: 24518220.
  • Williams M, Eatrides J, Kim J, Talwar H, Esposito N, Szabunio M, Ismail-Khan R, Kiluk J, Lee M, Laronga C, Khakpour N. Comparison of breast magnetic resonance imaging clinical tumor size with pathologic tumor size in patients status post-neoadjuvant chemotherapy. Am J Surg. 2013 Oct;206(4):567-573. Pubmedid: 23809673.
  • Lee MC, Bhati RS, von Rottenthaler EE, Reagan AM, Karver SB, Reich RR, Quinn GP. Therapy choices and quality of life in young breast cancer survivors: a short-term follow-up. Am J Surg. 2013 Nov;206(5):625-631. Pubmedid: 24016705. Pmcid: PMC4503361.
  • Walsh N, Greene J, Catherine Lee M. Tuberculous adenopathy masquerading as locally advanced breast cancer. Breast J. 2013 Jan;19(1):106-107. Pubmedid: 23279334.
  • Doren EL, Parikh RP, Laronga C, Hiro ME, Sun W, Lee MC, Smith PD, Fulp WJ. Sequelae of fat grafting postmastectomy: an algorithm for management of fat necrosis. Eplasty. 2013 Jan;12:e53. Pubmedid: 23308300. Pmcid: PMC3516285.
  • Walsh N, Kiluk JV, Sun W, Khakpour N, Laronga C, Lee MC. Ipsilateral nodal recurrence after axillary dissection for breast cancer. J Surg Res. 2012 Sep;177(1):81-86. Pubmedid: 22498028.
  • Lee MC, Joh JE, Chau A. Axillary staging prior to neoadjuvant chemotherapy: the roles of sentinel lymph node biopsy and axillary ultrasonography. Cancer Control. 2012 Oct;19(4):277-285. Pubmedid: 23037495.
  • Joh JE, Esposito NN, Kiluk JV, Laronga C, Khakpour N, Soliman H, Catherine Lee M. Pathologic Tumor Response of Invasive Lobular Carcinoma to Neo-adjuvant Chemotherapy. Breast J. 2012 Nov;18(6):569-574. Pubmedid: 23034096.
  • Joh JE, Esposito NN, Kiluk JV, Laronga C, Lee MC, Loftus L, Soliman H, Boughey JC, Reynolds C, Lawton TJ, Acs PI, Gordan L, Acs G. The effect of Oncotype DX recurrence score on treatment recommendations for patients with estrogen receptor-positive early stage breast cancer and correlation with estimation of recurrence risk by breast cancer specialists. Oncologist. 2012 Jun;16(11):1520-1526. Pubmedid: 22016474. Pmcid: PMC3233285.
  • Lee MC, Plews R, Rawal B, Kiluk JV, Loftus L, Laronga C. Factors affecting lymph node yield in patients undergoing axillary node dissection for primary breast cancer: a single-institution review. Ann Surg Oncol. 2012 Jun;19(6):1818-1824. Pubmedid: 22203185.
  • Turaga KK, Chau A, Eatrides JM, Kiluk JV, Khakpour N, Laronga C, Lee MC. Selective application of routine preoperative axillary ultrasonography reduces costs for invasive breast cancers. Oncologist. 2012 Jan;16(7):942-948. Pubmedid: 21572122. Pmcid: PMC3228129.
  • Joh JE, Han G, Kiluk JV, Laronga C, Khakpour N, Lee MC. Indications for axillary ultrasound use in breast cancer patients. Clin Breast Cancer. 2012 Dec;12(6):433-437. Pubmedid: 23062709.
  • Kiluk JV, Lee MC, Park CK, Meade T, Minton S, Harris E, Kim J, Laronga C. Male Breast Cancer: Management and Follow-up Recommendations. Breast J. 2011 Sep;17(5):503-509. Pubmedid: 21883641.
  • Pimiento JM, Lee MC, Esposito NN, Kiluk JV, Khakpour N, Carter WB, Han G, Laronga C. Role of axillary staging in women diagnosed with ductal carcinoma in situ with microinvasion. J Oncol Pract. 2011 Sep;7(5):309-313. Pubmedid: 22211128. Pmcid: PMC3170064.
  • Pimiento JM, Gadgil PV, Santillan AA, Lee MC, Esposito NN, Kiluk JV, Khakpour N, Hartley TL, Yeh IT, Laronga C. Phyllodes tumors: race-related differences. J Am Coll Surg. 2011 Oct;213(4):537-542. Pubmedid: 21856184.
  • Lee MC, Eatrides J, Chau A, Han G, Kiluk JV, Khakpour N, Cox CE, Carter WB, Laronga C. Consequences of axillary ultrasound in patients with T2 or greater invasive breast cancers. Ann Surg Oncol. 2011 Jan;18(1):72-77. Pubmedid: 20585876.
  • Kiluk JV, Khakpour N, Lee MC, Lowe J, Harris E, Szabunio M, Laronga C. Management of abnormal Rotter's lymph nodes identified on preoperative breast magnetic resonance imaging. Am Surg. 2011 Jan;77(1):E10-E12. Pubmedid: 21396292.
  • Lee MC, Gray J, Han HS, Plosker S. Fertility and reproductive considerations in premenopausal patients with breast cancer. Cancer Control. 2010 Jul;17(3):162-172. Pubmedid: 20664513.
  • Lee M, Rogers K, Griffith K, Diehl K, Breslin T, Cimmino V, Chang A, Newman L, Sabel M. Determinants of breast conservation rates: reasons for mastectomy at a comprehensive cancer center. Breast J. 2009 Jan;15(1):34-40. Pubmedid: 19141132.
  • Laronga C, Lee MC, McGuire KP, Meade T, Carter WB, Hoover S, Cox CE. Indications for sentinel lymph node biopsy in the setting of prophylactic mastectomy. J Am Coll Surg. 2009 Dec;209(6):746-752. Pubmedid: 19959044.
  • Lee MC, Kilbride KE. Timing of Axillary Staging. Ann Surg Oncol. 2009 Apr;16(4):1065-1065. Pubmedid: 19198950.
  • Lee M, Newman L. Management of patients with locally advanced breast cancer. Surg Clin North Am. 2007 Apr;87(2):379-398. Pubmedid: 17498533.
  • Lee M, Jagsi R. Postmastectomy radiation therapy: indications and controversies. Surg Clin North Am. 2007 Apr;87(2):511-526. Pubmedid: 17498541.
  • Chorost M, Lee M, Yeoh C, Molina M, Ghosh B. Unknown primary. J Surg Oncol. 2004 Sep;87(4):191-203. Pubmedid: 15334635.
  • Lee M, Lehman JA J, Tantri M, Parker M, Wagner D. Bilateral reduction mammoplasty in an adolescent population: adolescent bilateral reduction mammoplasty. J Craniofac Surg. 2003 Sep;14(5):691-695. Pubmedid: 14501330.