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Filippo Veglia, PhD

Academic Rank: Assistant Member

Overview

  Dr. Veglia’s research interest is to investigate metabolic and molecular mechanisms of immune response to cancers. His current research efforts are focused on the study of the role of myeloid cells in thwarting immune and therapeutic responses to glioblastoma (GBM). His research is also focused on the design of novel strategies for the therapeutic targeting of myeloid cells.   


Discipline

    • Immunology
    • Neuro-Oncology
    • Immunology

Education & Training

Fellowship:

  • Tor Vergata University, PhD - Immunology and Applied Biotechnology
  • University of Rome "Sapienza", MS - Biology Applied to Biomedical Research
Research

  Dr. Veglia’s research interest is to investigate metabolic and molecular mechanisms of immune response to cancers. His current research efforts are focused on the study of the role of myeloid cells in thwarting immune and therapeutic responses to glioblastoma (GBM). His research is also focused on the design of novel strategies for the therapeutic targeting of myeloid cells.   

Publications

  • Ugolini A, Tyurin V, Tyurina Y, Tsyganov E, Donthireddy L, Kagan VE, Gabrilovich DI, Veglia F. Polymorphonuclear myeloid-derived suppressor cells limit antigen cross-presentation by dendritic cells in cancer. JCI Insight. 2020 Jun. Pubmedid: 32584791.
  • Mastio J, Condamine T, Dominguez G, Kossenkov AV, Donthireddy L, Veglia F, Lin C, Wang F, Fu S, Zhou J, Viatour P, Lavilla-Alonso S, Polo AT, Tcyganov EN, Mulligan C, Nam B, Bennett J, Masters G, Guarino M, Kumar A, Nefedova Y, Vonderheide RH, Languino LR, Abrams SI, Gabrilovich DI. Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs. J Exp Med. 2019 Sep.216(9):2150-2169. Pubmedid: 31239386. Pmcid: PMC6719429.
  • Veglia F, Tyurin VA, Blasi M, De Leo A, Kossenkov AV, Donthireddy L, To TKJ, Schug Z, Basu S, Wang F, Ricciotti E, DiRusso C, Murphy ME, Vonderheide RH, Lieberman PM, Mulligan C, Nam B, Hockstein N, Masters G, Guarino M, Lin C, Nefedova Y, Black P, Kagan VE, Gabrilovich DI. Fatty acid transport protein 2 reprograms neutrophils in cancer. Nature. 2019 May.569(7754):73-78. Pubmedid: 30996346. Pmcid: PMC6557120.