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Cindy Tofthagen, PhD, APRN, AOCNP


Dr. Tofthagen's focus is on management of chemotherapy related side effects.


    • Health Outcomes & Behavior Program

Education & Training


  • Harvard Cancer Center- University of Massachusetts-Boston, Post doc - Cancer and Health Disparities

Dr. Tofthagen's research interests primarily focus on management of chemotherapy related side effects including: chemotherapy induced peripheral neuropathy, neuropathic pain and cognitive dysfunction.


  • Buck HG, Lyons K, Barrison P, Cairns P, Mason T, Tofthagen C, Kip K. Caregivers' Loss of the Dyadic Experience after Their Care Partners' Death. West J Nurs Res. 2021 Jan.193945921990426. Pubmedid: 33514300. Pmcid: PMC8319212.
  • Buck HG, Cairns P, BPharm NE, Hernandez DF, Mason TM, Bell J, Kip KE, Barrison P, Tofthagen C. Accelerated Resolution Therapy: Randomized Controlled Trial of a Complicated Grief Intervention. Am J Hosp Palliat Care. 2020 Oct.37(10):791-799. Pubmedid: 31960705. Pmcid: PMC8168719.
  • Chlan LL, Johnson PO, Peterson PE, Striegel L, Au G, Fritsche A, Bursiek A, Engelmann A, Tofthagen C. Strategies to Promote Nurses' Engagement in Clinical Research: Description of Two Nurse Scholar Programs. J Prof Nurs. 2020 Jun.36(3):111-115. Pubmedid: 32527631.
  • Tofthagen C, Hernandez DF, Mason TM, Buck HG, Kip KE. Complicated Grief With Post-Traumatic Stress Disorder Addressed With Accelerated Resolution Therapy: Case Discussions. Omega (Westport). 2020 Aug. Pubmedid: 32757692.
  • Mason TM, Tofthagen CS, Buck HG. Complicated Grief: Risk Factors, Protective Factors, and Interventions. J Soc Work End Life Palliat Care. 2020 Apr.16(2):151-174. Pubmedid: 32233740.
  • Tofthagen CS, Cheville AL, Loprinzi CL. The Physical Consequences of Chemotherapy-Induced Peripheral Neuropathy. Curr Oncol Rep. 2020 Apr.22(5):50. Pubmedid: 32323068.
  • Tofthagen C, Visovsky C, Dominic S, McMillan S. Neuropathic symptoms, physical and emotional well-being, and quality of life at the end of life. Support Care Cancer. 2019 Sep.27(9):3357-3364. Pubmedid: 30623244. Pmcid: PMC6616011.
  • Chlan LL, Tofthagen C, Terzic A. The Regenerative Horizon: Opportunities for Nursing Research and Practice. J Nurs Scholarsh. 2019 Nov.51(6):651-660. Pubmedid: 31566894. Pmcid: PMC6842049.
  • Badana ANS, Marino VR, Templeman ME, McMillan SC, Tofthagen CS, Small BJ, Haley WE. Understanding the roles of patient symptoms and subjective appraisals in well-being among breast cancer patients. Support Care Cancer. 2019 Mar.27(11):4245-4252. Pubmedid: 30847702.
  • Mason TM, Tofthagen CS. Complicated Grief of Immediate Family Caregivers: A Concept Analysis. ANS Adv Nurs Sci. 2019 Jul.42(3):255-265. Pubmedid: 30531354.
  • Latchman J, Guastella A, Tofthagen C. Neurologic Complications: Effects of Ipilimumab and Nivolumab Therapy in Patients With Metastatic Melanoma. Clin J Oncol Nurs. 2019 Aug.23(4):355-358. Pubmedid: 31322610.
  • Tofthagen C, McMillan SC. An Academic Perspective on Publishing in Oncology Nursing. Semin Oncol Nurs. 2018 Nov.34(4):393-401. Pubmedid: 30270141.
  • Tofthagen C, Visovsky C, Eckelman E, Clatterbuck B, Leggatt M, Buck H. Starting a nurse-led clinic for patients with peripheral neuropathy. Nursing. 2018 Aug.48(8):39-42. Pubmedid: 30045238.
  • Sampayo V, Tofthagen C. Hyperglycemia and Cancer: An Algorithm to Guide Oncology Nurses
. Clin J Oncol Nurs. 2017 Jun.21(3):345-352. Pubmedid: 28524903.
  • Guastella A, Latchman J, Tofthagen CS. Opioid-Induced Hyperalgesia: Clinical Implications for Advanced Practice Nurses in Oncology. Clin J Oncol Nurs. 2017 Jun.21(3):294-296. Pubmedid: 28524890.
  • Tofthagen CS, Kip K, Witt A, McMillan SC. Complicated Grief: Risk Factors, Interventions, and Resources for Oncology Nurses. Clin J Oncol Nurs. 2017 Jun.21(3):331-337. Pubmedid: 28524889.
  • Hart K, Tofthagen C, Wang HL. Development and Evaluation of a Lung Cancer Screening Decision Aid. Clin J Oncol Nurs. 2016 Oct.20(5):557-559. Pubmedid: 27668377.
  • Tofthagen C, Kip KE, Passmore D, Loy I, Berry DL. Usability and Acceptability of a Web-Based Program for Chemotherapy-Induced Peripheral Neuropathy. Comput Inform Nurs. 2016 Jul.34(7):322-329. Pubmedid: 27116414.
  • Paterson CL, Lengacher CA, Donovan KA, Kip KE, Tofthagen CS. Body Image in Younger Breast Cancer Survivors: A Systematic Review. Cancer Nurs. 2016 Jan.39(1):E39-E58. Pubmedid: 25881807. Pmcid: PMC4607543.
  • Tofthagen C, Boses S, Healy G, Jooma N. Evaluation of Group Acupuncture for Cancer-Related Symptoms: A Retrospective Analysis. J Palliat Med. 2015 Oct.18(10):878-880. Pubmedid: 26218367.
  • Budhrani PH, Lengacher CA, Kip K, Tofthagen C, Jim H. An integrative review of subjective and objective measures of sleep disturbances in breast cancer survivors. Clin J Oncol Nurs. 2015 Apr.19(2):185-191. Pubmedid: 25840384.
  • Latchman J, Guastella A, Tofthagen C. 5-Fluorouracil toxicity and dihydropyrimidine dehydrogenase enzyme: implications for practice. Clin J Oncol Nurs. 2014 Oct.18(5):581-585. Pubmedid: 25253112. Pmcid: PMC5469441.
  • Smith EM, Campbell G, Tofthagen C, Kottschade L, Collins ML, Warton C, Ghosh B, Ronis DL, Mallory GA, Visovsky C. Nursing knowledge, practice patterns, and learning preferences regarding chemotherapy-induced peripheral neuropathy. Oncol Nurs Forum. 2014 Nov.41(6):669-679. Pubmedid: 25355022.
  • Budhrani PH, Lengacher CA, Kip KE, Tofthagen C, Jim H. Minority Breast Cancer Survivors: The Association between Race/Ethnicity, Objective Sleep Disturbances, and Physical and Psychological Symptoms. Nurs Res Pract. 2014 Aug.2014:858403. Pubmedid: 25101174. Pmcid: PMC4101933.
  • Tofthagen C, Gonzalez L, Visovsky C, Akers A. Self-management of oxaliplatin-related peripheral neuropathy in colorectal cancer survivors. Chemother Res Pract. 2013 Sep.2013:547932. Pubmedid: 24062949. Pmcid: PMC3766977.
  • McMillan SC, Tofthagen C, Small B, Karver S, Craig D. Trajectory of medication-induced constipation in patients with cancer. Oncol Nurs Forum. 2013 May.40(3):E92-E100. Pubmedid: 23615153. Pmcid: PMC5385997.
  • Tofthagen C, McAllister RD, Visovsky C. Peripheral neuropathy caused by Paclitaxel and docetaxel: an evaluation and comparison of symptoms. J Adv Pract Oncol. 2013 Jul.4(4):204-215. Pubmedid: 25032002. Pmcid: PMC4093436.
  • Tofthagen C, Donovan KA, Morgan MA, Shibata D, Yeh Y. Oxaliplatin-induced peripheral neuropathy's effects on health-related quality of life of colorectal cancer survivors. Support Care Cancer. 2013 Dec.21(12):3307-3313. Pubmedid: 23903798. Pmcid: PMC5385999.
  • Tofthagen C, Visovsky CM, Hopgood R. Chemotherapy-induced peripheral neuropathy: an algorithm to guide nursing management. Clin J Oncol Nurs. 2013 Apr.17(2):138-144. Pubmedid: 23538249. Pmcid: PMC5469440.
  • Tofthagen C, Visovsky C, Berry DL. Strength and balance training for adults with peripheral neuropathy and high risk of fall: current evidence and implications for future research. Oncol Nurs Forum. 2012 Sep.39(5):E416-E424. Pubmedid: 22940521. Pmcid: PMC5385995.
  • Tofthagen C. Threats to validity in retrospective studies. J Adv Pract Oncol. 2012 May.3(3):181-183. Pubmedid: 25031944. Pmcid: PMC4093311.
  • Tofthagen C, Overcash J, Kip K. Falls in persons with chemotherapy-induced peripheral neuropathy. Support Care Cancer. 2012 Mar.20(3):583-589. Pubmedid: 21380613. Pmcid: PMC5386000.
  • Stark L, Tofthagen C, Visovsky C, McMillan SC. The Symptom Experience of Patients with Cancer. J Hosp Palliat Nurs. 2012 Jan.14(1):61-70. Pubmedid: 22639548. Pmcid: PMC3358129.
  • Tofthagen CS, McMillan SC, Kip KE. Development and psychometric evaluation of the chemotherapy-induced peripheral neuropathy assessment tool. Cancer Nurs. 2011 Jul.34(4):E10-E20. Pubmedid: 21242773.
  • Tofthagen C, McAllister RD, McMillan SC. Peripheral neuropathy in patients with colorectal cancer receiving oxaliplatin. Clin J Oncol Nurs. 2011 Apr.15(2):182-188. Pubmedid: 21444285.
  • Tofthagen C. Patient perceptions associated with chemotherapy-induced peripheral neuropathy. Clin J Oncol Nurs. 2010 Jun.14(3):E22-E28. Pubmedid: 20529785.
  • McMillan S, Tofthagen C, Morgan M. Relationships among pain, sleep disturbances, and depressive symptoms in outpatients from a comprehensive cancer center. Oncol Nurs Forum. 2008 Jul.35(4):603-611. Pubmedid: 18591165.
  • Tofthagen CS, McMillan SC. Pain, neuropathic symptoms, and physical and mental well-being in persons with cancer. Cancer Nurs. 33(6):436-444. Pubmedid: 21479139. Pmcid: PMC3070947.