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Quincy  Mo

Quincy Mo, PhD

Program: Biostatistics and Bioinformatics

Research Program: Cancer Biology & Evolution Program

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  • Overview

    As a biostatistician and bioinformatician, my goal is to develop new statistical methods and software for analysis of cancer genomic and clinical data. For collaborative research, I would like to use my expertise to help other researchers identify biomarkers that contribute to cancer initiation, development and progression.

    Associations

    • Biostatistics and Bioinformatics
    • Cancer Biology & Evolution Program

    Education & Training

    Graduate:

    • Lehigh University, MS - Statistics
    • Lehigh University, PhD - Molecular Biology
  • Research Interest

    My research interests focus on the development of new statistical methods and software for integrative analysis of multi-omics data typically generated from microarray and next generation sequencing experiments. My clinical research collaborations primarily focus on design and analysis of clinical trials and examination of clinical and treatment factors predictive of clinical outcomes. My collaborations in basic science and genomic studies mainly focus on statistical analysis and mining of the data generated by experiments using microarray or high-throughput sequencing technology.

  • Publications

    • Bhutada I, Khambati F, Cheng SY, Tiek DM, Duckett D, Lawrence H, Vogelbaum MA, Mo Q, Chellappan SP, Padmanabhan J. CDK7 and CDK9 inhibition interferes with transcription, translation, and stemness, and induces cytotoxicity in GBM irrespective of temozolomide sensitivity. Neurooncol. 2024 Jan.26(1):70-84. Pubmedid: 37551745. Pmcid: PMC10768977.
    • Sarfraz H, Bari S, Whiting J, Sur M, Mo Q, Armitage M, Costa RLB. A Cohort Study of the Antitumor Efficacy and Toxicity Profile of Alpelisib for Metastatic or Locally Advanced HR+, HER2- Breast Cancer: A Single-Institution Experience. Oncology-Basel. 2023 Nov.1-11. Pubmedid: 38011835.
    • Mo Q, Yun S, Sallman DA, Vincelette ND, Peng G, Zhang L, Lancet JE, Padron E. Integrative molecular subtypes of acute myeloid leukemia. Blood Cancer J. 2023 May.13(1):71. Pubmedid: 37156780. Pmcid: PMC10167212.
    • Chalise P, Kwon D, Fridley BL, Mo Q. Statistical Methods for Integrative Clustering of Multi-omics Data. Methods Mol Biol. 2023 Mar.2629:73-93. Pubmedid: 36929074.
    • Rose A, Zhang L, Jain AG, Poovathukaran Babu A, Sokol L, Saeed H, Mo Q, Fan W, Zhang X. Delineation of clinical course, outcomes, and prognostic factors in patients with T-cell prolymphocytic leukemia. Am J Hematol. 2023 Jun.98(6):913-921. Pubmedid: 36964941.
    • Giuliano A, Kuter B, Pilon-Thomas S, Whiting J, Mo Q, Leav B, Sirak B, Cubitt C, Dukes C, Isaacs-Soriano K, Kennedy K, Ball S, Dong N, Jain A, Hwu P, Lancet J. Safety and immunogenicity of a third dose of mRNA-1273 vaccine among cancer patients. Cancer Commun (Lond). 2023 Jul.43(7):749-764. Pubmedid: 37377402. Pmcid: PMC10354405.
    • Soupir AC, Tian Y, Stewart PA, Nunez-Lopez YO, Manley BJ, Pellini B, Bloomer AM, Zhang J, Mo Q, Marchion DC, Liu M, Koomen JM, Siegel EM, Wang L. Detectable Lipidomes and Metabolomes by Different Plasma Exosome Isolation Methods in Healthy Controls and Patients with Advanced Prostate and Lung Cancer. Int J Mol Sci. 2023 Jan.24(3). Pubmedid: 36768152. Pmcid: PMC9916336.
    • Park MA, Zaw T, Yoder SJ, Gomez M, Genilo-Delgado M, Basinski T, Katende E, Dam A, Mok SRS, Monteiro A, Mohammadi A, Jeong DK, Jiang K, Centeno BA, Hodul P, Malafa M, Fleming J, Chen DT, Mo Q, Teer JK, Permuth JB. A pilot study to evaluate tissue- and plasma-based DNA driver mutations in a cohort of patients with pancreatic intraductal papillary mucinous neoplasms. G3 (Bethesda). 2023 Feb.13(2). Pubmedid: 36454217. Pmcid: PMC9911050.
    • Dukes CW, Potez M, Lancet J, Kuter BJ, Whiting J, Mo Q, Leav B, Wang H, Vanas JS, Cubitt CL, Isaacs-Soriano K, Kennedy K, Rathwell J, Diaz Cobo J, O'Nan W, Sirak B, Dong N, Tan E, Hwu P, Giuliano AR, Pilon-Thomas S. Neutralizing Antibody Response following a Third Dose of the mRNA-1273 Vaccine among Cancer Patients. Vaccines (Basel). 2023 Dec.12(1). Pubmedid: 38250826. Pmcid: PMC10818923.
    • Jusino S, Rivera-Rivera Y, Chardón-Colón C, Rodríguez-Rodríguez PC, Román-González J, Juliá-Hernández VS, Isidro A, Mo Q, Saavedra HI. Sustained Shugoshin 1 downregulation reduces tumor growth and metastasis in a mouse xenograft tumor model of triple-negative breast cancer. Cell Div. 2023 Apr.18(1):6. Pubmedid: 37122033. Pmcid: PMC10150544.
    • Kuykendall AT, Mo Q, Sallman DA, Ali NA, Chan O, Yun S, Sweet KL, Padron E, Lancet JE, Komrokji RS. Disease-related thrombocytopenia in myelofibrosis is defined by distinct genetic etiologies and is associated with unique prognostic correlates. Cancer. 2022 Oct.128(19):3495-3501. Pubmedid: 35942592.
    • Gallen C, Dukes CW, Aldrich A, Macaisa L, Mo Q, Cubitt CL, Pilon-Thomas S, Giuliano AR, Czerniecki BJ, Costa RLB. Long-Term CD4+ T-Cell and Immunoglobulin G Immune Responses in Oncology Workers following COVID-19 Vaccination: An Interim Analysis of a Prospective Cohort Study. Vaccines (Basel). 2022 Nov.10(11). Pubmedid: 36423026. Pmcid: PMC9696551.
    • Giuliano AR, Lancet JE, Pilon-Thomas S, Dong N, Jain AG, Tan E, Ball S, Tworoger SS, Siegel EM, Whiting J, Mo Q, Cubitt CL, Dukes CW, Hensel JA, Keenan RJ, Hwu P. Evaluation of Antibody Response to SARS-CoV-2 mRNA-1273 Vaccination in Patients With Cancer in Florida. JAMA Oncol. 2022 May.8(5):748-754. Pubmedid: 35266953. Pmcid: PMC8914884.
    • Tan E, Whiting J, Xie H, Imanirad I, Carballido E, Felder S, Frakes J, Mo Q, Walko C, Permuth JB, Sommerer K, Kim R, Anaya DA, Fleming JB, Sahin IH. BRAF Mutations Are Associated with Poor Survival Outcomes in Advanced-stage Mismatch Repair-deficient/Microsatellite High Colorectal Cancer. Oncologist. 2022 Mar.27(3):191-197. Pubmedid: 35274712. Pmcid: PMC8914499.
    • Nikolos F, Hayashi K, Hoi XP, Alonzo ME, Mo Q, Kasabyan A, Furuya H, Trepel J, Di Vizio D, Guarnerio J, Theodorescu D, Rosser C, Apolo A, Galsky M, Chan KS. Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors. Nat Commun. 2022 Mar.13(1):1487. Pubmedid: 35347124. Pmcid: PMC8960844.
    • Peres LC, Colin-Leitzinger C, Teng M, Dutil J, Alugubelli RR, DeAvila G, Teer JK, Du D, Mo Q, Siegel EM, Hampton O, Alsina M, Brayer J, Blue B, Baz R, Siqueira Silva A, Nishihori T, Shain KH, Gillis N. Racial and ethnic differences in clonal hematopoiesis, tumor markers, and outcomes of patients with multiple myeloma. Blood Adv. 2022 Jun.6(12):3767-3778. Pubmedid: 35500227. Pmcid: PMC9631567.
    • Bag A, Schultz A, Bhimani S, Stringfield O, Dominguez W, Mo Q, Cen L, Adeegbe D. Coupling the immunomodulatory properties of the HDAC6 inhibitor ACY241 with Oxaliplatin promotes robust anti-tumor response in non-small cell lung cancer. Oncoimmunology. 2022 Feb.11(1):2042065. Pubmedid: 35223194. Pmcid: PMC8865306.
    • Szwarc MM, Hai L, Maurya VK, Rajapakshe K, Perera D, Ittmann MM, Mo Q, Lin Y, Bettini ML, Coarfa C, Lydon JP. Histopathologic and transcriptomic phenotypes of a conditional RANKL transgenic mouse thymus. Cytokine. 2022 Dec.160:156022. Pubmedid: 36099756. Pmcid: PMC10255830.
    • Selfridge JM, Sinner HF, Whiting J, Sun W, Mallory MA, Hoover SJ, Kiluk JV, Khakpour N, Czerniecki BJ, Laronga C, Mo Q, Lee MC. Effect of Microporous Polysaccharide Particles in Patients Undergoing Mastectomy. Clin Breast Cancer. 2022 Dec.22(8):e922-e927. Pubmedid: 36055918.
    • Xia BT, Otto AK, Allenson K, Kocab M, Fan W, Mo Q, Denbo JW, Malafa MP, Permuth JB, Kim DW, Fleming JB, Reblin M, Hodul PJ. Patient-caregiver dyads in pancreatic cancer: identification of patient and caregiver factors associated with caregiver well-being. J Behav Med. 2022 Dec.45(6):935-946. Pubmedid: 35986871.
    • Wood AC, Zhang Y, Mo Q, Cen L, Fontaine J, Hoffe SE, Frakes J, Dineen SP, Pimiento JM, Walko CM, Mehta R. Evaluation of Tumor DNA Sequencing Results in Patients with Gastric and Gastroesophageal Junction Adenocarcinoma Stratified by TP53 Mutation Status. Oncologist. 2022 Apr.27(4):307-313. Pubmedid: 35380714. Pmcid: PMC8982441.
    • Tan E, Whiting J, Knepper T, Xie H, Imanirad I, Carballido E, Felder S, Frakes J, Mo Q, Permuth JB, Somerer K, Kim R, Anaya DA, Fleming JB, Walko C, Sahin IH. Core Homologous Recombination Mutations and Improved Survival in Nonpancreatic GI Cancers. Am J Clin Oncol. 2022 Apr.45(4):137-141. Pubmedid: 35320814.
    • Hunter AM, Newman H, DeZern AE, Steensma DP, Niyongere S, Roboz GJ, Mo Q, Chan O, Gerds A, Sallman DA, Dominguez-Viqueira W, Letson C, Balasis ME, Ball M, Kruer T, Zhang H, Lancet JE, List AF, Sekeres MA, Komrokji RS, Padron E. Integrated Human and Murine Clinical Study Establishes Clinical Efficacy of Ruxolitinib in Chronic Myelomonocytic Leukemia. Clin Cancer Res. 2021 Nov.27(22):6095-6105. Pubmedid: 34253584. Pmcid: PMC8595542.
    • Sallman DA, DeZern AE, Garcia-Manero G, Steensma DP, Roboz GJ, Sekeres MA, Cluzeau T, Sweet KL, McLemore A, McGraw KL, Puskas J, Zhang L, Yao J, Mo Q, Nardelli L, Al Ali NH, Padron E, Korbel G, Attar EC, Kantarjian HM, Lancet JE, Fenaux P, List AF, Komrokji RS. Eprenetapopt (APR-246) and Azacitidine in TP53-Mutant Myelodysplastic Syndromes. J Clin Oncol. 2021 May.39(14):1584-1594. Pubmedid: 33449813. Pmcid: PMC8099410.
    • Jayani RV, Pidala J, Jim H, Whiting J, Mo Q, Mishra A. Association of Patient-Reported Physical Activity on Allogeneic Hematopoietic Cell Transplant Outcomes. Clin Hematol Int. 2021 Mar.3(1):34-39. Pubmedid: 34595465. Pmcid: PMC8432326.
    • Jayani RV, Pidala J, Jim H, Whiting J, Mo Q, Mishra A. Association of Patient-Reported Physical Activity on Allogeneic Hematopoietic Cell Transplant Outcomes. Clin Hematol Int. 2021 Mar.3(1):34-39.
    • Dong N, Castillo Tokumori F, Isenalumhe L, Zhang Y, Tandon A, Knepper TC, Mo Q, Shao H, Zhang L, Sokol L. Large granular lymphocytic leukemia - A retrospective study of 319 cases. Am J Hematol. 2021 Jul.96(7):772-780. Pubmedid: 33819354.
    • Cheng N, Mo Q, Donelson J, Wang L, Breton G, Rodney GG, Wang J, Hirschi KD, Wehrens XHT, Nakata PA. Crucial Role of Mammalian Glutaredoxin 3 in Cardiac Energy Metabolism in Diet-induced Obese Mice Revealed by Transcriptome Analysis. Int J Biol Sci. 2021 Jul.17(11):2871-2883. Pubmedid: 34345213. Pmcid: PMC8326124.
    • Wu F, Nie S, Yao Y, Huo T, Li X, Wu X, Zhao J, Lin YL, Zhang Y, Mo Q, Song Y. Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth. Theranostics. 2021 Jul.11(17):8172-8184. Pubmedid: 34373735. Pmcid: PMC8344022.
    • Horton TM, Hoff FW, van Dijk A, Jenkins GN, Morrison D, Bhatla T, Hogan L, Romanos-Sirakis E, Meyer J, Carroll WL, Qiu Y, Wang T, Mo Q, Kornblau SM. The effects of sample handling on proteomics assessed by reverse phase protein arrays (RPPA): Functional proteomic profiling in leukemia. J Proteomics. 2021 Feb.233:104046. Pubmedid: 33212251. Pmcid: PMC7877245.
    • Gajzer D, Logothetis CN, Sallman DA, Calon G, Babu A, Chan O, Vincelette ND, Volpe VO, Al Ali NH, Basra P, Talati C, Kuykendall AT, Mo Q, Padron E, Sweet K, Komrokji RS, Lancet JE, Yun S, Zhang L. MYC overexpression is associated with an early disease progression from MDS to AML. Leuk Res. 2021 Dec.111:106733. Pubmedid: 34749168. Pmcid: PMC8643343.
    • Mo Q, Wan L, Schell MJ, Jim H, Tworoger SS, Peng G. Integrative Analysis Identifies Multi-Omics Signatures That Drive Molecular Classification of Uveal Melanoma. Cancers (Basel). 2021 Dec.13(24). Pubmedid: 34944787. Pmcid: PMC8699355.
    • Padmanabhan J, Saha B, Powell C, Mo Q, Perez BA, Chellappan S. Inhibitors Targeting CDK9 Show High Efficacy against Osimertinib and AMG510 Resistant Lung Adenocarcinoma Cells. Cancers (Basel). 2021 Aug.13(15). Pubmedid: 34359807. Pmcid: PMC8345430.
    • Jia Y, Kodumudi KN, Ramamoorthi G, Basu A, Snyder C, Wiener D, Pilon-Thomas S, Grover P, Zhang H, Greene MI, Mo Q, Tong Z, Chen YZ, Costa RLB, Han H, Lee C, Soliman H, Conejo-Garcia JR, Koski G, Czerniecki BJ. Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway. Mol Ther. 2021 Apr.29(4):1541-1556. Pubmedid: 33412308. Pmcid: PMC8058490.
    • Fu Y, Kaneko K, Lin HY, Mo Q, Xu Y, Suganami T, Ravn P, Fukuda M. Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus. Endocrinology. 2020 Sep.161(9). Pubmedid: 32603429.
    • Shields M, Mo Q, Armitage M, Sharpe SC, Costa RLB. A systematic review and meta-analysis of selected toxicity endpoints of alpelisib. Oncotarget. 2020 Oct.11(42):3793-3799. Pubmedid: 33144920. Pmcid: PMC7584237.
    • Yun S, Chan O, Kerr D, Vincelette ND, Idrees A, Mo Q, Sweet K, Lancet JE, Kharfan-Dabaja MA, Zhang L, Sokol L. Survival outcomes in blastic plasmacytoid dendritic cell neoplasm by first-line treatment and stem cell transplant. Blood Adv. 2020 Jul.4(14):3435-3442. Pubmedid: 32722779. Pmcid: PMC7391135.
    • Mo Q, Li R, Adeegbe DO, Peng G, Chan KS. Integrative multi-omics analysis of muscle-invasive bladder cancer identifies prognostic biomarkers for frontline chemotherapy and immunotherapy. Commun Biol. 2020 Dec.3(1):784. Pubmedid: 33335285. Pmcid: PMC7746703.
    • Subramonian D, Phanhthilath N, Rinehardt H, Flynn S, Huo Y, Zhang J, Messer K, Mo Q, Huang S, Lesperance J, Zage PE. Regorafenib is effective against neuroblastoma in vitro and in vivo and inhibits the RAS/MAPK, PI3K/Akt/mTOR and Fos/Jun pathways. Brit J Cancer. 2020 Aug.123(4):568-579. Pubmedid: 32457362. Pmcid: PMC7434894.
    • Kamoun A, Reyniès A, Allory Y, Sjödahl G, Robertson AG, Seiler R, Hoadley KA, Groeneveld CS, Al-Ahmadie H, Choi W, Castro MAA, Fontugne J, Eriksson P, Mo Q, Kardos J, Zlotta A, Hartmann A, Dinney CP, Bellmunt J, Powles T, Malats N, Chan KS, Kim WY, McConkey DJ, Black PC, Dyrskjøt L, Höglund M, Lerner SP, Real FX, Radvanyi F. A Consensus Molecular Classification of Muscle-invasive Bladder Cancer. Eur Urol. 2020 Apr.77(4):420-433. Pubmedid: 31563503. Pmcid: PMC7690647.
    • Abbas-Aghababazadeh F, Mo Q, Fridley BL. Statistical genomics in rare cancer. Semin Cancer Biol. 2020 Apr.61:1-10. Pubmedid: 31437624. Pmcid: PMC7771546.
    • Kamoun A, de Reyniès A, Allory Y, Sjödahl G, Robertson AG, Seiler R, Hoadley KA, Groeneveld CS, Al-Ahmadie H, Choi W, Castro MAA, Fontugne J, Eriksson P, Mo Q, Kardos J, Zlotta A, Hartmann A, Dinney CP, Bellmunt J, Powles T, Malats N, Chan KS, Kim WY, McConkey DJ, Black PC, Dyrskjøt L, Höglund M, Lerner SP, Real FX, Radvanyi F, Aine M, Bernard-Pierrot I, Czerniak B, Gibb EA, Kim J, Kwiatkowski DJ, Lebret T, Liedberg F, Siefker-Radtke AA, Sirab N, Taber A, Weinstein JN. Reply To Kenneth B. Yatai, Mark J. Dunning, Dennis Wang. Consensus Genomic Subtypes of Muscle-invasive Bladder Cancer: A Step in the Right Direction but Still a Long Way To Go. Eur Urol 2020;77:434-5. Eur Urol. 2020 Apr.77(4):436-438. Pubmedid: 32037144.
    • Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo HC, Toneff MJ, Nguyen T, Bu W, Jiang W, Arnold J, Gu F, He J, Jebakumar D, Walker K, Li Y, Mo Q, Westbrook TF, Zong C, Rao A, Sreekumar A, Rosen JM, Zhang XH. Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms. Nat Cell Biol. 2019 Sep.21(9):1113-1126. Pubmedid: 31451770. Pmcid: PMC6726554.
    • Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H. SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep.10(1):4042. Pubmedid: 31492871. Pmcid: PMC6731344.
    • Vasaikar S, Huang C, Wang X, Petyuk VA, Savage SR, Wen B, Dou Y, Zhang Y, Shi Z, Arshad OA, Gritsenko MA, Zimmerman LJ, McDermott JE, Clauss TR, Moore RJ, Zhao R, Monroe ME, Wang YT, Chambers MC, Slebos RJC, Lau KS, Mo Q, Ding L, Ellis M, Thiagarajan M, Kinsinger CR, Rodriguez H, Smith RD, Rodland KD, Liebler DC, Liu T, Zhang B. Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities. Cell. 2019 May.177(4):1035-1049.e19. Pubmedid: 31031003.
    • Lee YC, Kurtova AV, Xiao J, Nikolos F, Hayashi K, Tramel Z, Jain A, Chen F, Chokshi M, Lee C, Bao G, Zhang X, Shen J, Mo Q, Jung SY, Rowley D, Chan KS. Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung. Nat Commun. 2019 May.10(1):2131. Pubmedid: 31086186. Pmcid: PMC6513865.
    • Szwarc MM, Hai L, Gibbons WE, Mo Q, Lanz RB, DeMayo FJ, Lydon JP. Early growth response 1 transcriptionally primes the human endometrial stromal cell for decidualization. J Steroid Biochem -. 2019 May.189:283-290. Pubmedid: 30711473. Pmcid: PMC6566904.
    • Sallman DA, Komrokji RS, Sweet KL, Mo Q, McGraw KL, Duong VH, Zhang L, Nardelli LA, Padron E, List AF, Lancet JE. A phase 2 trial of the oral smoothened inhibitor glasdegib in refractory myelodysplastic syndromes (MDS). Leuk Res. 2019 Jun.81:56-61. Pubmedid: 31030089. Pmcid: PMC7787349.
    • Bu W, Liu Z, Jiang W, Nagi C, Huang S, Edwards DP, Jo E, Mo Q, Creighton CJ, Hilsenbeck SG, Leavitt AD, Lewis MT, Wong STC, Li Y. Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes. Cancer Res. 2019 Jan.79(1):61-71. Pubmedid: 30401712. Pmcid: PMC6318055.
    • Bharadwaj U, Eckols TK, Xu X, Kasembeli MM, Chen Y, Adachi M, Song Y, Mo Q, Lai SY, Tweardy DJ. Correction: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma. Oncotarget. 2019 Feb.10(16):1603. Pubmedid: 30899429. Pmcid: PMC6422187.
    • Kaneko K, Fu Y, Lin HY, Cordonier EL, Mo Q, Gao Y, Yao T, Naylor J, Howard V, Saito K, Xu P, Chen SS, Chen MH, Xu Y, Williams KW, Ravn P, Fukuda M. Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition. J Clin Invest. 2019 Aug.130. Pubmedid: 31403469.
    • Liang F, Shi R, Mo Q. A Split-and-Merge Approach for Singular Value Decomposition of Large-Scale Matrices. Stat Interface. 2019 Aug.9(4):453-459. Pubmedid: 31440324. Pmcid: PMC6706079.
    • Jiao L, Maity S, Coarfa C, Rajapakshe K, Chen L, Jin F, Putluri V, Tinker LF, Mo Q, Chen F, Sen S, Sangi-Haghpeykar H, El-Serag HB, Putluri N. A Prospective Targeted Serum Metabolomics Study of Pancreatic Cancer in Postmenopausal Women. Cancer Prev Res (Phila). 2019 Apr.12(4):237-246. Pubmedid: 30723176. Pmcid: PMC6445762.
    • Donelson J, Wang Q, Monroe TO, Jiang X, Zhou J, Yu H, Mo Q, Sun Q, Marini JC, Wang X, Nakata PA, Hirschi KD, Wang J, Rodney GG, Wehrens XHT, Cheng N. Cardiac-specific ablation of glutaredoxin 3 leads to cardiac hypertrophy and heart failure. Physiol Rep. 2019 Apr.7(8):e14071. Pubmedid: 31033205. Pmcid: PMC6487472.
    • Szwarc MM, Hai L, Gibbons WE, White LD, Mo Q, Kommagani R, Lanz RB, DeMayo FJ, O’Malley BW, Lydon JP. Retinoid signaling controlled by SRC-2 in decidualization revealed by transcriptomics. Reproduction. 2018 Oct.156(5):387-395. Pubmedid: 30325183. Pmcid: PMC6208442.
    • Vasquez YM, Wang X, Wetendorf M, Franco HL, Mo Q, Wang T, Lanz RB, Young SL, Lessey BA, Spencer TE, Lydon JP, DeMayo FJ. FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation. PLoS Genet. 2018 Nov.14(11):e1007787. Pubmedid: 30452456. Pmcid: PMC6277115.
    • Mo Q, Nikolos F, Chen F, Tramel Z, Lee YC, Hayashi K, Xiao J, Shen J, Chan KS. Prognostic Power of a Tumor Differentiation Gene Signature for Bladder Urothelial Carcinomas. J Natl Cancer Inst. 2018 May.110(5):448-459. Pubmedid: 29342309. Pmcid: PMC6279371.
    • Lu L, Wen Y, Yao Y, Chen F, Wang G, Wu F, Wu J, Narayanan P, Redell M, Mo Q, Song Y. Glucocorticoids Inhibit Oncogenic RUNX1-ETO in Acute Myeloid Leukemia with Chromosome Translocation t(8;21). Theranostics. 2018 Mar.8(8):2189-2201. Pubmedid: 29721072. Pmcid: PMC5928880.
    • Mo Q, Shen R, Guo C, Vannucci M, Chan KS, Hilsenbeck SG. A fully Bayesian latent variable model for integrative clustering analysis of multi-type omics data. Biostatistics. 2018 Jan.19(1):71-86. Pubmedid: 28541380. Pmcid: PMC6455926.
    • Szwarc MM, Hai L, Gibbons WE, Peavey MC, White LD, Mo Q, Lonard DM, Kommagani R, Lanz RB, DeMayo FJ, Lydon JP. Human endometrial stromal cell decidualization requires transcriptional reprogramming by PLZF. Biol Reprod. 2018 Jan.98(1):15-27. Pubmedid: 29186366. Pmcid: PMC5819842.
    • Szwarc MM, Hai L, Gibbons WE, White LD, Mo Q, Kommagani R, Lanz RB, DeMayo FJ, O'Malley BW, Lydon JP. Retinoid Signaling Controlled by SRC-2 in Decidualization Revealed by Transcriptomics. Reproduction. 2018 Aug. Pubmedid: 30072571.
    • Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, Ellis MJ, Rosen JM. FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation. Cancer Res. 2018 Aug.78(15):4229-4240. Pubmedid: 29844125. Pmcid: PMC6072612.
    • Adams NR, Vasquez YM, Mo Q, Gibbons W, Kovanci E, DeMayo FJ. WNK lysine deficient protein kinase 1 regulates human endometrial stromal cell decidualization, proliferation, and migration in part through mitogen-activated protein kinase 7. Biol Reprod. 2017 Sep.97(3):400-412. Pubmedid: 29025069. Pmcid: PMC6109229.
    • Yang L, Liu L, Gao H, Pinnamaneni JP, Sanagasetti D, Singh VP, Wang K, Mathison M, Zhang Q, Chen F, Mo Q, Rosengart T, Yang J. The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis. J Hematol Oncol. 2017 Oct.10(1):159. Pubmedid: 28974232. Pmcid: PMC5627455.
    • Agarwal N, Iyer D, Gabbi C, Saha P, Patel SG, Mo Q, Chang B, Goswami B, Schubert U, Kopp JB, Lewis DE, Balasubramanyam A. HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD. Sci Rep. 2017 Oct.7(1):13362. Pubmedid: 29042644. Pmcid: PMC5645472.
    • Tan YD, Zhang XHF, Mo Q. New statistical methods for estimation of recombination fractions in F population. BMC Bioinformatics. 2017 Oct.18(Suppl 11):404. Pubmedid: 28984187. Pmcid: PMC5629630.
    • Mo Q, Salley J, Roshan T, Baer LA, May FJ, Jaehnig EJ, Lehnig AC, Guo X, Tong Q, Nuotio-Antar AM, Shamsi F, Tseng YH, Stanford KI, Chen MH. Identification and characterization of a supraclavicular brown adipose tissue in mice. JCI Insight. 2017 Jun.2(11). Pubmedid: 28570265. Pmcid: PMC5453704.
    • Haller M, Mo Q, Imamoto A, Lamb DJ. Murine model indicates 22q11.2 signaling adaptor is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 05.114(19):4981-4986. Pubmedid: 28439006. Pmcid: PMC5441740.
    • Bharadwaj U, Eckols TK, Xu X, Kasembeli MM, Chen Y, Adachi M, Song Y, Mo Q, Lai SY, Tweardy DJ. Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma. Oncotarget. 2016 May.7(18):26307-26330. Pubmedid: 27027445. Pmcid: PMC5041982.
    • Feng Z, Yao Y, Zhou C, Chen F, Wu F, Wei L, Liu W, Dong S, Redell M, Mo Q, Song Y. Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia. J Hematol Oncol. 2016 Mar.9:24. Pubmedid: 26970896. Pmcid: PMC4789278.
    • Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH. Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016 Jun.18(6):632-644. Pubmedid: 27183469. Pmcid: PMC4884142.
    • Tian G, Courtney AN, Jena B, Heczey A, Liu D, Marinova E, Guo L, Xu X, Torikai H, Mo Q, Dotti G, Cooper LJ, Metelitsa LS. CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo. J Clin Invest. 2016 Jun.126(6):2341-2355. Pubmedid: 27183388. Pmcid: PMC4887157.
    • Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH. Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016 Jun.18(7):822. Pubmedid: 27350446.
    • Woodfield SE, Guo RJ, Liu Y, Major AM, Hollingsworth EF, Indiviglio S, Whittle SB, Mo Q, Bean AJ, Ittmann M, Lopez-Terrada D, Zage PE. Neuroblastoma patient outcomes, tumor differentiation, and ERK activation are correlated with expression levels of the ubiquitin ligase UBE4B. Genes Cancer. 2016 Jan.7(1-2):13-26. Pubmedid: 27014418. Pmcid: PMC4773702.
    • Yong LK, Lai S, Liang Z, Poteet E, Chen F, van Buren G, Fisher W, Mo Q, Chen C, Yao Q. Overexpression of Semaphorin-3E enhances pancreatic cancer cell growth and associates with poor patient survival. Oncotarget. 2016 Dec.7(52):87431-87448. Pubmedid: 27911862. Pmcid: PMC5349999.
    • Brooks M, Mo Q, Krasnow R, Ho PL, Lee YC, Xiao J, Kurtova A, Lerner S, Godoy G, Jian W, Castro P, Chen F, Rowley D, Ittmann M, Chan KS. Positive association of collagen type I with non-muscle invasive bladder cancer progression. Oncotarget. 2016 Dec.7(50):82609-82619. Pubmedid: 27655672. Pmcid: PMC5347718.
    • Matatall KA, Jeong M, Chen S, Sun D, Chen F, Mo Q, Kimmel M, King KY. Chronic Infection Depletes Hematopoietic Stem Cells through Stress-Induced Terminal Differentiation. Cell Rep. 2016 Dec.17(10):2584-2595. Pubmedid: 27926863. Pmcid: PMC5161248.
    • Heller G, Mo Q. Estimating the concordance probability in a survival analysis with a discrete number of risk groups. Lifetime Data Anal. 2016 Apr.22(2):263-279. Pubmedid: 26022558. Pmcid: PMC4886856.
    • Breaux M, Lewis K, Valanejad L, Iakova P, Chen F, Mo Q, Medrano E, Timchenko L, Timchenko N. p300 Regulates Liver Functions by Controlling p53 and C/EBP Family Proteins through Multiple Signaling Pathways. Mol Cell Biol. 2015 Sep.35(17):3005-3016. Pubmedid: 26100016. Pmcid: PMC4525310.
    • Holdman XB, Welte T, Rajapakshe K, Pond A, Coarfa C, Mo Q, Huang S, Hilsenbeck SG, Edwards DP, Zhang X, Rosen JM. Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer. Breast Cancer Res. 2015 Nov.17:141. Pubmedid: 26581390. Pmcid: PMC4652386.
    • Shen J, Peng Y, Wei L, Zhang W, Yang L, Lan L, Kapoor P, Ju Z, Mo Q, Shih IeM, Uray IP, Wu X, Brown PH, Shen X, Mills GB, Peng G. ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors. Cancer Discov. 2015 Jul.5(7):752-767. Pubmedid: 26069190. Pmcid: PMC4497871.
    • Kurtova AV, Xiao J, Mo Q, Pazhanisamy S, Krasnow R, Lerner SP, Chen F, Roh TT, Lay E, Ho PL, Chan KS. Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance. Nature. 2015 Jan.517(7533):209-213. Pubmedid: 25470039. Pmcid: PMC4465385.
    • Kang YK, Putluri N, Maity S, Tsimelzon A, Ilkayeva O, Mo Q, Lonard D, Michailidis G, Sreekumar A, Newgard CB, Wang M, Tsai SY, Tsai MJ, O'Malley BW. CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC. PLoS Genet. 2015 Apr.11(4):e1005116. Pubmedid: 25830341. Pmcid: PMC4382186.
    • Maker AV, Ito H, Mo Q, Weisenberg E, Qin LX, Turcotte S, Maithel S, Shia J, Blumgart L, Fong Y, Jarnagin WR, DeMatteo RP, D'Angelica MI. Genetic evidence that intratumoral T-cell proliferation and activation are associated with recurrence and survival in patients with resected colorectal liver metastases. Cancer Immunol Res. 2015 Apr.3(4):380-388. Pubmedid: 25600439. Pmcid: PMC4390462.
    • Pedrotti S, Giudice J, Dagnino-Acosta A, Knoblauch M, Singh RK, Hanna A, Mo Q, Hicks J, Hamilton S, Cooper TA. The RNA-binding protein Rbfox1 regulates splicing required for skeletal muscle structure and function. Hum Mol Genet. 2015 Apr.24(8):2360-2374. Pubmedid: 25575511. Pmcid: PMC4380076.
    • Zhang L, Deng L, Chen F, Yao Y, Wu B, Wei L, Mo Q, Song Y. Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer. Oncotarget. 2014 Nov.5(21):10665-10677. Pubmedid: 25359765. Pmcid: PMC4279401.
    • Mohammed S, Evans C, VanBuren G, Hodges SE, Silberfein E, Artinyan A, Mo Q, Issazadeh M, McElhany AL, Fisher WE. Treatment of bacteriobilia decreases wound infection rates after pancreaticoduodenectomy. HPB (Oxford). 2014 Jun.16(6):592-598. Pubmedid: 23992045. Pmcid: PMC4048081.
    • Amirian ES, Bondy ML, Mo Q, Bainbridge MN, Scheurer ME. Presence of viral DNA in whole-genome sequencing of brain tumor tissues from the cancer genome atlas. J Virol. 2014 Jan.88(1):774. Pubmedid: 24353289. Pmcid: PMC3911725.
    • Peng G, Chun-Jen Lin C, Mo W, Dai H, Park YY, Kim SM, Peng Y, Mo Q, Siwko S, Hu R, Lee JS, Hennessy B, Hanash S, Mills GB, Lin SY. Genome-wide transcriptome profiling of homologous recombination DNA repair. Nat Commun. 2014 Feb.5:3361. Pubmedid: 24553445. Pmcid: PMC4017859.
    • Van Buren G, Bloomston M, Hughes SJ, Winter J, Behrman SW, Zyromski NJ, Vollmer C, Velanovich V, Riall T, Muscarella P, Trevino J, Nakeeb A, Schmidt CM, Behrns K, Ellison EC, Barakat O, Perry KA, Drebin J, House M, Abdel-Misih S, Silberfein EJ, Goldin S, Brown K, Mohammed S, Hodges SE, McElhany A, Issazadeh M, Jo E, Mo Q, Fisher WE. A randomized prospective multicenter trial of pancreaticoduodenectomy with and without routine intraperitoneal drainage. Ann Surg. 2014 Apr.259(4):605-612. Pubmedid: 24374513.
    • Dong S, Jia C, Zhang S, Fan G, Li Y, Shan P, Sun L, Xiao W, Li L, Zheng Y, Liu J, Wei H, Hu C, Zhang W, Chin YE, Zhai Q, Li Q, Liu J, Jia F, Mo Q, Edwards DP, Huang S, Chan L, O'Malley BW, Li X, Wang C. The REGγ proteasome regulates hepatic lipid metabolism through inhibition of autophagy. Cell Metab. 2013 Sep.18(3):380-391. Pubmedid: 24011073. Pmcid: PMC3813599.
    • Marin-Muller C, Li D, Bharadwaj U, Li M, Chen C, Hodges SE, Fisher WE, Mo Q, Hung MC, Yao Q. A tumorigenic factor interactome connected through tumor suppressor microRNA-198 in human pancreatic cancer. Clin Cancer Res. 2013 Nov.19(21):5901-5913. Pubmedid: 23989979. Pmcid: PMC3920728.
    • Ganly I, Ricarte Filho J, Eng S, Ghossein R, Morris LG, Liang Y, Socci N, Kannan K, Mo Q, Fagin JA, Chan TA. Genomic dissection of Hurthle cell carcinoma reveals a unique class of thyroid malignancy. J Clin Endocrinol Metab. 2013 May.98(5):E962-E972. Pubmedid: 23543667. Pmcid: PMC5393465.
    • Mo Q, Wang S, Seshan VE, Olshen AB, Schultz N, Sander C, Powers RS, Ladanyi M, Shen R. Pattern discovery and cancer gene identification in integrated cancer genomic data. Proc Natl Acad Sci U S A. 2013 Mar.110(11):4245-4250. Pubmedid: 23431203. Pmcid: PMC3600490.
    • Kollmeier MA, Fidaleo A, Pei X, Cohen G, Zaider M, Mo Q, Cox B, Yamada Y, Zelefsky MJ. Favourable long-term outcomes with brachytherapy-based regimens in men ≤60 years with clinically localized prostate cancer. BJU Int. 2013 Jun.111(8):1231-1236. Pubmedid: 23551568.
    • Kobos R, Nagai M, Tsuda M, Merl MY, Saito T, Laé M, Mo Q, Olshen A, Lianoglou S, Leslie C, Ostrovnaya I, Antczak C, Djaballah H, Ladanyi M. Combining integrated genomics and functional genomics to dissect the biology of a cancer-associated, aberrant transcription factor, the ASPSCR1-TFE3 fusion oncoprotein. J Pathol. 2013 Apr.229(5):743-754. Pubmedid: 23288701. Pmcid: PMC4083568.
    • Shen R, Wang S, Mo Q. SPARSE INTEGRATIVE CLUSTERING OF MULTIPLE OMICS DATA SETS. Ann Appl Stat. 2013 Apr.7(1):269-294. Pubmedid: 24587839. Pmcid: PMC3935438.
    • Ito H, Mo Q, Qin LX, Viale A, Maithel SK, Maker AV, Shia J, Kingham P, Allen P, DeMatteo RP, Fong Y, Jarnagin WR, D'Angelica M. Gene expression profiles accurately predict outcome following liver resection in patients with metastatic colorectal cancer. PLoS One. 2013.8(12):e81680. Pubmedid: 24339954. Pmcid: PMC3858250.
    • Shen R, Mo Q, Schultz N, Seshan VE, Olshen AB, Huse J, Ladanyi M, Sander C. Integrative subtype discovery in glioblastoma using iCluster. PLoS One. 2012 Sep.7(4):e35236. Pubmedid: 22539962. Pmcid: PMC3335101.
    • , Mo Q. Comprehensive genomic characterization of squamous cell lung cancers. Nature. 2012 Sep.489(7417):519-525. Pubmedid: 22960745. Pmcid: PMC3466113.
    • Morrogh M, Andrade VP, Patil AJ, Qin LX, Mo Q, Sakr R, Arroyo CD, Brogi E, Morrow M, King TA. Differentially expressed genes in window trials are influenced by the wound-healing process: lessons learned from a pilot study with anastrozole. J Surg Res. 2012 Jul.176(1):121-132. Pubmedid: 21777924. Pmcid: PMC4509686.
    • Tonorezos ES, Vega GL, Sklar CA, Chou JF, Moskowitz CS, Mo Q, Church TS, Ross R, Janiszewski PM, Oeffinger KC. Adipokines, body fatness, and insulin resistance among survivors of childhood leukemia. Pediatr Blood Cancer. 2012 Jan.58(1):31-36. Pubmedid: 21254377. Pmcid: PMC3520427.
    • Mo Q. A fully Bayesian hidden Ising model for ChIP-seq data analysis. Biostatistics. 2012 Jan.13(1):113-128. Pubmedid: 21914728.
    • Gao H, Chakraborty G, Lee-Lim AP, Mo Q, Decker M, Vonica A, Shen R, Brogi E, Brivanlou AH, Giancotti FG. The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites. Cell. 2012 Aug.150(4):764-779. Pubmedid: 22901808. Pmcid: PMC3711709.
    • Koutcher L, Sherman E, Fury M, Wolden S, Zhang Z, Mo Q, Stewart L, Schupak K, Gelblum D, Wong R, Kraus D, Shah J, Zelefsky M, Pfister D, Lee N. Concurrent cisplatin and radiation versus cetuximab and radiation for locally advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2011 Nov.81(4):915-922. Pubmedid: 20947269.
    • Fang F, Turcan S, Rimner A, Kaufman A, Giri D, Morris LG, Shen R, Seshan V, Mo Q, Heguy A, Baylin SB, Ahuja N, Viale A, Massague J, Norton L, Vahdat LT, Moynahan ME, Chan TA. Breast cancer methylomes establish an epigenomic foundation for metastasis. Sci Transl Med. 2011 Mar.3(75):75ra25. Pubmedid: 21430268. Pmcid: PMC3146366.
    • Affer M, Dao S, Liu C, Olshen AB, Mo Q, Viale A, Lambek CL, Marr TG, Clarkson BD. Gene Expression Differences between Enriched Normal and Chronic Myelogenous Leukemia Quiescent Stem/Progenitor Cells and Correlations with Biological Abnormalities. J Oncol. 2011 Jul.2011:798592. Pubmedid: 21436996. Pmcid: PMC3062978.
    • Deutsch I, Zelefsky MJ, Zhang Z, Mo Q, Zaider M, Cohen G, Cahlon O, Yamada Y. Comparison of PSA relapse-free survival in patients treated with ultra-high-dose IMRT versus combination HDR brachytherapy and IMRT. Brachytherapy. 2011 Feb.9(4):313-318. Pubmedid: 20685176.
    • Suzuki K, Kachala SS, Kadota K, Shen R, Mo Q, Beer DG, Rusch VW, Travis WD, Adusumilli PS. Prognostic immune markers in non-small cell lung cancer. Clin Cancer Res. 2011 Aug.17(16):5247-5256. Pubmedid: 21659461.
    • Gupta A, Young RJ, Karimi S, Sood S, Zhang Z, Mo Q, Gutin PH, Holodny AI, Lassman AB. Isolated diffusion restriction precedes the development of enhancing tumor in a subset of patients with glioblastoma. Ajnr Am J Neuroradiol. 2011 Aug.32(7):1301-1306. Pubmedid: 21596805. Pmcid: PMC4040369.
    • Gerecitano J, Portlock C, Hamlin P, Moskowitz CH, Noy A, Straus D, Schulman P, Dumitrescu O, Sarasohn D, Pappanicholaou J, Iasonos A, Zhang Z, Mo Q, Horanlli E, Rojas CN, Zelenetz AD, O'Connor OA. Phase I trial of weekly and twice-weekly bortezomib with rituximab, cyclophosphamide, and prednisone in relapsed or refractory non-Hodgkin lymphoma. Clin Cancer Res. 2011 Apr.17(8):2493-2501. Pubmedid: 21346146. Pmcid: PMC5639472.
    • Goodman KA, Wiegner EA, Maturen KE, Zhang Z, Mo Q, Yang G, Gibbs IC, Fisher GA, Koong AC. Dose-escalation study of single-fraction stereotactic body radiotherapy for liver malignancies. Int J Radiat Oncol Biol Phys. 2010 Oct.78(2):486-493. Pubmedid: 20350791.
    • Fuchsjäger MH, Pucar D, Zelefsky MJ, Zhang Z, Mo Q, Ben-Porat LS, Shukla-Dave A, Wang L, Reuter VE, Hricak H. Predicting post-external beam radiation therapy PSA relapse of prostate cancer using pretreatment MRI. Int J Radiat Oncol Biol Phys. 2010 Nov.78(3):743-750. Pubmedid: 20133067. Pmcid: PMC2891893.
    • Mo Q, Liang F. A hidden Ising model for ChIP-chip data analysis. Bioinformatics. 2010 Mar.26(6):777-783. Pubmedid: 20110277.
    • Mo Q, Liang F. Bayesian modeling of ChIP-chip data through a high-order Ising model. Biometrics. 2010 Dec.66(4):1284-1294. Pubmedid: 20128774.
    • Small CM, Carney GE, Mo Q, Vannucci M, Jones AG. A microarray analysis of sex- and gonad-biased gene expression in the zebrafish: evidence for masculinization of the transcriptome. BMC Genomics. 2009 Dec.10:579. Pubmedid: 19958554. Pmcid: PMC2797025.
    • Popovic N, Bridenbaugh EA, Neiger JD, Hu JJ, Vannucci M, Mo Q, Trzeciakowski J, Miller MW, Fossum TW, Humphrey JD, Wilson E. Transforming growth factor-beta signaling in hypertensive remodeling of porcine aorta. Am J Physiol Heart Circ Physiol. 2009 Dec.297(6):H2044-H2053. Pubmedid: 19717726. Pmcid: PMC2793137.
    • Papapetrou EP, Tomishima MJ, Chambers SM, Mica Y, Reed E, Menon J, Tabar V, Mo Q, Studer L, Sadelain M. Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc Natl Acad Sci U S A. 2009 Aug.106(31):12759-12764. Pubmedid: 19549847. Pmcid: PMC2722286.
    • Mo Q, Lu S, Garippa C, Brownstein MJ, Simon NG. Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus. J Steroid Biochem -. 2009 Apr.114(3-5):135-143. Pubmedid: 19429443.
    • Dahl DB, Bohannan Z, Mo Q, Vannucci M, Tsai J. Assessing side-chain perturbations of the protein backbone: a knowledge-based classification of residue Ramachandran space. J Mol Biol. 2008 May.378(3):749-758. Pubmedid: 18377931. Pmcid: PMC2440669.
    • Simon NG, Mo Q, Hu S, Garippa C, Lu SF. Hormonal pathways regulating intermale and interfemale aggression. Int Rev Neurobiol. 2006 Aug.73:99-123. Pubmedid: 16737902.
    • Mo Q, Lu SF, Simon NG. Dehydroepiandrosterone and its metabolites: differential effects on androgen receptor trafficking and transcriptional activity. J Steroid Biochem -. 2006 Apr.99(1):50-58. Pubmedid: 16524719.
    • Mo Q, Lu SF, Hu S, Simon NG. DHEA and DHEA sulfate differentially regulate neural androgen receptor and its transcriptional activity. Brain Res Mol Brain Res. 2004 Jul.126(2):165-172. Pubmedid: 15249140.
    • Lu SF, Mo Q, Hu S, Garippa C, Simon NG. Dehydroepiandrosterone upregulates neural androgen receptor level and transcriptional activity. J Neurobiol. 2003 Nov.57(2):163-171. Pubmedid: 14556282.
  • Grants

    • Title: Targeting Tumor Repopulation and the Immune Microenvironment to Overcome Chemoresistance
      Sponsor: Nat Institutes of Health
      PI: Mo, Q.
    • Title: (00014262) Mechanisms of Radioresistance and Strategies for Radiosensitization in Ovarian Clear Cell Carcinoma
      Sponsor: Nat Institutes of Health
      PI: Mo, Q.

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