Immuno-Oncology Program Metrics

View the clinical trials, grants and publications from the Cancer Epidemiology Program.

Clinical Trials
CLINICAL TRIAL 18783
A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression
Condition: Malignant Hematology
Intervention: Alkeran (Melphalan); FK506 (Tacrolimus); Melphalan (); Pacritinib (); Rapamune (Sirolimus); Rapamycin (Sirolimus); Sirolimus (); Tacrolimus (); busulfan (); fludarabine (Fludarabine phosphate)

CLINICAL TRIAL 18786
A Phase 2, Randomized, Multi-institutional Study of Nivolumab and Ipilimumab versus Nivolumab, Ipilimumab and Stereotactic Body Radiation Therapy for Metastatic Merkel Cell Carcinoma
Condition: Cutaneous
Intervention: BMS-936558 (Nivolumab); Ipilimumab (); Nivolumab (Opdivo); Yervoy (Ipilimumab)

CLINICAL TRIAL 19337
A Pilot Study Utilizing a HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+ Breast Cancer
Condition: Breast
Intervention: DC1 Vaccine (); Herceptin (Trastuzumab); Paraplatin (carboplatin); Pertuzumab (); Taxotere (docetaxel); Trastuzumab (); carboplatin (); docetaxel (); rhuMAb HER2 (Trastuzumab)

CLINICAL TRIAL 19487
A Phase Ib/II Study to Evaluate the Safety, Feasibility and Efficacy of Nivolumab or Nivolumab in Combination with Azacitidine in Patients with Recurrent, Resectable Osteosarcoma
Condition: Sarcoma
Intervention: BMS-936558 (Nivolumab); Nivolumab (Opdivo); azacitidine (5-azacitidine)

CLINICAL TRIAL 19580
A Phase 1/2 Dose Escalation and Dose Expansion Study of BA3011 in Patients with Advanced Solid Tumors
Condition: Multiple
Intervention: BA3011 (); BMS-936558 (Nivolumab); Nivolumab (Opdivo)

CLINICAL TRIAL 19724
Managed Access Program (MAP) To Provide Access To CTL019, For Acute Lymphoblastic Leukemia (ALL) Or Diffuse Large B-Cell Lymphoma (DLBCL) Patients With Out Of Specification Leukapheresis Product And/Or Manufactured Tisagenlecleucel Out Of Specification For Commercial Release
Condition: Malignant Hematology
Intervention:

CLINICAL TRIAL 19837
Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients with Soft Tissue Sarcoma
Condition: Sarcoma
Intervention: IL-2 (Interleukin-2); MESNA (); TIL (); cyclophosphamide (); cytoxan (cyclophosphamide); fludarabine (Fludarabine phosphate)

CLINICAL TRIAL 19936
Maintenance Systemic Therapy versus Local Consolidative Therapy (Lct) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (Nsclc): A Randomized Phase II/III Trial
Condition: Genitourinary
Intervention: Alimta (Pemetrexed); Gemzar (gemcitabine); Pembrolizumab (Keytruda); Pemetrexed (); Taxotere (docetaxel); docetaxel (); gemcitabine ()

CLINICAL TRIAL 19877
A Randomized Phase 2 Study of CDX-1127 (Varlilumab) in Combination with Nivolumab in Patients with Relapsed or Refractory Aggressive B-Cell Lymphomas
Condition: Malignant Hematology
Intervention: BMS-936558 (Nivolumab); Nivolumab (Opdivo); Varlilumab ()

CLINICAL TRIAL 19961
A Phase 1B/2 Study To Evaluate The Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of Eq001 In Subjects With Newly Diagnosed Acute Graft Versus Host Disease
Condition: Malignant Hematology
Intervention: EQ001 (); Placebo ()

CLINICAL TRIAL 20042
CD8 Depleted, Non-Engrafting, HLA Mismatched Unrelated Donor Lymphocyte Infusion in Patients with MDS and Secondary AML
Condition: Malignant Hematology
Intervention: Cladribine (); Cytarabine (Cytosine Arabinoside); Daunomycin (daunorubicin); G-CSF (); Idarubicin (); Zevados (Idarubicin); daunorubicin ()

CLINICAL TRIAL 20126
Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (CTRL-ALT-D)
Condition: Malignant Hematology
Intervention:

CLINICAL TRIAL 20131
Reduced-Intensity Fludarabine, Melphalan, and Total Body Irradiation Conditioning for Transplantation of HLA-Haploidentical Related Hematopoietic Cells (Haplo-HCT) For Patients With Hematologic Malignancies
Condition: Malignant Hematology
Intervention: Alkeran (Melphalan); Cellcept (Mycophenolate Mofetil); FK506 (Tacrolimus); G-CSF (); Melphalan (); Mycophenolate Mofetil (); Rapamune (Sirolimus); Rapamycin (Sirolimus); Sirolimus (); Tacrolimus (); cyclophosphamide (); cytoxan (cyclophosphamide); fludarabine (Fludarabine phosphate)

CLINICAL TRIAL 20132
Phase 1/2 Dose-Escalation and Expansion Study of FLX475 Alone and in Combination with Pembrolizumab in Advanced Cancer
Condition: Multiple
Intervention: FLX475 (); Pembrolizumab (Keytruda)

CLINICAL TRIAL 20163
EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non©\Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNature©\driven Analysis
Condition: Thoracic
Intervention: Alimta (Pemetrexed); MK-3475 (Keytruda); Paraplatin (carboplatin); Pemetrexed (); carboplatin ()

CLINICAL TRIAL 20173
A Phase 2, Multi-arm, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of IPI-549 Administered in Combination with Front-line Treatment Regimens in Patients with Locally Advanced and/or Metastatic Triple-Negative Breast Cancer or Renal Cell Carcinoma
Condition: Breast
Intervention: Atezolizumab (Tecentriq); Avastin (Bevacizumab); Bevacizumab (); IPI-549 (); Nab-paclitaxel (Abraxane)

CLINICAL TRIAL 20251
A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR T cells in subjects with Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma (SPEARHEAD 1 Study)
Condition: Immunotherapy
Intervention: ADP-A2M4 (); MESNA (); cyclophosphamide (); cytoxan (cyclophosphamide); fludarabine (Fludarabine phosphate)

CLINICAL TRIAL 20253
Open Label, Multi-Center, Phase 1b Clinical Trial to Evaluate the Safety and Efficacy of Autologous CAR-BCMA T cells (CT053) in Patients With Relapsed and/or Refractory Multiple Myeloma
Condition: Multiple Myeloma
Intervention: CT053 ()

CLINICAL TRIAL 20274
A Phase II/III Randomized Study of Maintenance Nivolumab versus Observation in Patients with Locally Advanced, Intermediate Risk HPV Positive OPCA
Condition: Head & Neck
Intervention: BMS-936558 (Nivolumab); Nivolumab (Opdivo); Radiotherapy (); cisplatin ()

CLINICAL TRIAL 20305
Phase 1/1b Trial of Donor gamma delta T-cell Infusion for Treatment of Patients with Acute Myeloid Leukemia at High Risk of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
Condition: Malignant Hematology
Intervention: Donor T Cells ()

CLINICAL TRIAL 20348
Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III randomized study of chemoradiation versus chemoradiation plus Atezolizumab
Condition: Thoracic
Intervention: Atezolizumab (Tecentriq); Paraplatin (carboplatin); Radiotherapy (); carboplatin (); cisplatin (); etoposide ()

CLINICAL TRIAL 20306
A Phase 2 Open-Label, Multicenter, Study to Evaluate the Efficacy and Safety of Rivoceranib in Subjects with Recurrent or Metastatic Adenoid Cystic Carcinoma of All Anatomic Sites of Origin
Condition: Head & Neck
Intervention: Rivoceranib ()

CLINICAL TRIAL 20313
Neoadjuvant Immunotherapy with Intratumoral Tavokinogene Telseplasmid (Tavo) plus Electroporation in Combination with Intravenous Nivolumab in Patients with Operable Locally- Regionally Advanced Melanoma
Condition: Cutaneous
Intervention: BMS-936558 (Nivolumab); Nivolumab (Opdivo); Tavo-EP ()

CLINICAL TRIAL 20329
The PISCES study: A Multicenter Phase 2, Open-Label Study of Intratumoral Tavokinogene Telseplasmid (tavo, pIL-12) plus Electroporation in Combination with Intravenous Pembrolizumab in Patients with Stage III/IV Melanoma who are Progressing on either Pembrolizumab or Nivolumab Treatment
Condition: Cutaneous
Intervention: Pembrolizumab (Keytruda); Tavo-EP ()

CLINICAL TRIAL 20377
A Phase 2 Multicohort Study of Nivolumab in Combination with Docetaxel and Androgen Deprivation Therapy in Metastatic Hormone Sensitive Prostate Cancer Patients with DNA Damage Repair Defects or Inflamed Tumors
Condition: Genitourinary
Intervention: ADT (); BMS-936558 (Nivolumab); Firmagon (); Lupron (leuprolide acetate); Nivolumab (Opdivo); Taxotere (docetaxel); Zoladex (); docetaxel (); goserelin acetate (Zoladex)

CLINICAL TRIAL 20484
A Phase 2 Study of Donor-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-401) Administered to Patients with Acute Myeloid Leukemia (AML) following Hematopoietic Stem Cell Transplantation
Condition: Malignant Hematology
Intervention: MT-401 ()

CLINICAL TRIAL 20397
A Phase 2, Single-Arm, Open-Label Study of Itacitinib, for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy
Condition: Immunotherapy
Intervention: Itacitinib ()

CLINICAL TRIAL 20494
A Phase II Study of High Dose Bolus IL2 in Combination with Low Dose Ipilimumab Followed Sequentially by Nivolumab in Patients with Inoperable Stage III or Stage IV Melanoma Who Have Failed Prior Anti-PD1 Immunotherapy
Condition: Cutaneous
Intervention: Aldesleukin (Interleukin-2); BMS-936558 (Nivolumab); IL-2 (Interleukin-2); Interleukin-2 (); Ipilimumab (); Nivolumab (Opdivo); Proleukin (Interleukin-2); Yervoy (Ipilimumab)

CLINICAL TRIAL 20533
A Phase 1, Open-Label, Multicenter, Dose Escalation and Expansion Study of ONCR-177, an Oncolytic Herpes Simplex Virus for Intratumoral Injection, Alone and in Combination with PD-1 Blockade in Adult Subjects with Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors
Condition: Multiple
Intervention: ONCR-177 (); Pembrolizumab (Keytruda)

CLINICAL TRIAL 20557
A Phase II, Open-Label, Multicenter, Randomized Study of Efficacy and Safety of RO7198457 in Combination with Pembrolizumab versus Pembrolizumab in Patients with Previously Untreated Advanced Melanoma
Condition: Cutaneous
Intervention:

CLINICAL TRIAL 20575
A Phase 1 Study of CG0070 Combined with Nivolumab in Cisplatin Ineligible Patients with Muscle Invasive Bladder Cancer (MIBC)
Condition: Genitourinary
Intervention: BMS-936558 (Nivolumab); CG0070 (); DDM (); Nivolumab (Opdivo)

CLINICAL TRIAL 20571
Optimizing Cellular and Humoral Immunity to Pneumococcus by Vaccination with Pneumococcal 13-valent conjugate vaccine before and after CD19-targeted CAR T-cell Immunotherapy
Condition: Immunotherapy
Intervention: CD19 CAR T Cells (); PCV13 ()

CLINICAL TRIAL 20614
A Phase III, Multicneter, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Atezolizumab Given in Combination with Cabozantinib versus Cabozantinib Alone in Patients with Inoperable, Locally, Advanced, or Metastatic Renal Cell Carcinoma Who Experienced Radiographic Tumor Progression During or After Immune Checkpoint Inhibitor Treatment
Condition: Genitourinary
Intervention: Atezolizumab (Tecentriq); Cabozantinib (XL 184)

CLINICAL TRIAL 20619
A Phase 2 Multicenter, Open-label Study of Rucaparib as Treatment for Solid Tumors Associated with Deleterious Mutations in Homologous Recombination Repair Genes (LODESTAR)
Condition: Multiple
Intervention: AG-014447 (Rucaparib); CO-338 (Rucaparib); Not Applicable (); PF-01367338-BW (Rucaparib); Rucaparib ()

CLINICAL TRIAL 20711
A Phase 2, Single Arm Study of CG0070 Combined with Pembrolizumab in Patients with Non Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus Calmette-Guerin (BCG)
Condition: Genitourinary
Intervention: CG0070 (); DDM (); Pembrolizumab (Keytruda)

CLINICAL TRIAL 20712
A Phase I Study of Ipilimumab and Nivolumab in Advanced HIV- Associated Solid Tumors, with Expansion Cohorts in HIV-Associated Solid tumors and a Cohort of HIV- Associated Classical Hodgkin Lymphoma
Condition: Thoracic
Intervention: BMS-936558 (Nivolumab); Ipilimumab (); Nivolumab (Opdivo); Yervoy (Ipilimumab)

CLINICAL TRIAL 20720
S1827, MRI Brain Surveillance Alone Versus MRI Surveillance and Prophylactic Cranial Irradiation (PCI): A Randomized Phase III Trial in Small-Cell Lung Cancer (MAVERICK)
Condition: Thoracic
Intervention:

CLINICAL TRIAL 20722
Phase III Randomized Trial of Pleurectomy/Decortication plus Chemotherapy with or without Adjuvant Hemithoracic Intenstiy-Modulated Pleural Radiation Therapy (IMPRINT) for Malignant Pleural Mesothelioma (MPM)
Condition: Thoracic
Intervention:

CLINICAL TRIAL 20730
Randomized, Double-blind, Phase 3 Study of Tucatinib or Placebo in Combination with Ado-Trastuzumab Emtansine (T-DM1) for Subjects with Unresectable Locally-Advanced or Metastatic HER2+ Breast Cancer (HER2CLIMB-02)
Condition: Breast
Intervention: Trastuzumab emtansine (); Tucatinib ()

CLINICAL TRIAL 20837
Envasarc: A Pivitol Trial of Envafolimab, and Envafolimab in Combination with Ipilimumab, in Patients with Advanced or Metastatic Undifferentiated Pleomorphic Sarcoma or Myxofibrosarcoma Who Have Progressed on Prior Chemotherapy
Condition: Sarcoma
Intervention: Envafolimab (); Ipilimumab (); Yervoy (Ipilimumab)

CLINICAL TRIAL 20843
A Phase II Study of Belinostat and Guadecitabine for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma
Condition: Sarcoma
Intervention: Belinostat (); PXD101 (Belinostat); SGI-110 ()

CLINICAL TRIAL 20839
A Phase 3, Randomized, Open-label Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined with Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence (PIVOT-12)
Condition: Cutaneous
Intervention: BMS-936558 (Nivolumab); NKTR-214 (Bempegaldesleukin); Nivolumab (Opdivo)

CLINICAL TRIAL 20794
Neoadjuvant Cemiplimab in Stage I-II Merkel Cell Carcinoma: Safety and Biomarker Analysis
Condition: Cutaneous
Intervention: Cemiplimab (); REGN2810 (Cemiplimab)

CLINICAL TRIAL 20939
A Phase 1b/2 Open Label Umbrella Study of Sasanlimab Combined With Anti-Cancer Therapies Targeting Multiple Molecular Mechanisms in Participants with Non-Small Cell Lung Cancer (NSCLC)
Condition: Thoracic
Intervention: Binimetinib (); Encorafenib (); PF-06801591 (Sasanlimab); Sasanlimab ()

CLINICAL TRIAL 21026
A Phase II Study of Cemiplimab, an Anti-PD-1 Monoclonal Antibody, and ISA101b Vaccine in Patients with Recurrent/Metastatic HPV16 Positive Oropharyngeal Cancer who have Experienced Disease Progression with Prior Anti-PD-1 Therapy
Condition: Head & Neck
Intervention: Cemiplimab (); ISA101b (); REGN2810 (Cemiplimab)

CLINICAL TRIAL 21125
MElanoma Research Lymph Node Prediction Implementation National_001 (MERLIN_001)
Condition: Cutaneous
Intervention:

CLINICAL TRIAL 20903
A Phase II, Open-label, Multicenter, International Study of Durvalumab Following Radiation Therapy in Patients with Stage III, Unresectable Non-Small Cell Lung Cancer Who Are Ineligible for Chemotherapy (DUART)
Condition: Thoracic
Intervention: AMP-514 (Durvalumab); Durvalumab (); MEDI4736 (Durvalumab)

CLINICAL TRIAL 20888
Predicting the Quality of Response to Specific Treatments (PQRST) Chronic GVHD Cohort
Condition: Malignant Hematology
Intervention:

CLINICAL TRIAL 21135
Randomized, Placebo-Controlled, Phase II Trial Examining Ustekinumab for Prevention of Graft vs. Host Disease after Allogeneic Hematopoietic Cell Transplantation
Condition: Malignant Hematology
Intervention: FK506 (Tacrolimus); Tacrolimus (); Ustekinumab/placebo ()

CLINICAL TRIAL 21029
A Multicenter Phase II Trial of Paclitaxel with and without Nivolumab in Taxane Naïve, and Nivolumab and Cabozantinib in Taxane Pre-treated Subjects with Angiosarcoma
Condition: Sarcoma
Intervention: BMS-936558 (Nivolumab); Cabozantinib (XL 184); Nivolumab (Opdivo); Taxol (paclitaxel); paclitaxel ()

CLINICAL TRIAL 21089
Phase 2, Single-arm, Open-label Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer with Actionable Genomic Alterations and Progressed On or After Kinase Inhibitor Therapy and Platinum-based Chemotherapy (TROPION-Lung05)
Condition: Thoracic
Intervention: DS-1062a (); Not Applicable ()

CLINICAL TRIAL 21150
Effect of Prolonged Nightly Fasting (PNF) on Immunotherapy Treatment Outcomes in Patients with Advanced Head and Neck Cancer (HNSCC)-Role of Gut Microbiome
Condition: Head & Neck
Intervention:

CLINICAL TRIAL 21214
Association of Gender with Adverse Events, Prescribing Patterns and Oncologic outcomes in Patients being treated with Immuno-Oncology Agents
Condition: Cutaneous
Intervention:

CLINICAL TRIAL 21239
Randomized Phase II/III Study of Nivolumab plus Ipilimumab plus Sargramostim versus Nivolumab plus Ipilimumab in Patients with Unresectable Stage III or Stage IV Melanoma
Condition: Cutaneous
Intervention: BMS-936558 (Nivolumab); Ipilimumab (); Nivolumab (Opdivo); Sargramostim (); Yervoy (Ipilimumab)

CLINICAL TRIAL 21375
A Multicenter Validation of Genomic Subtyping and Whole Transcriptome Profiling for Predicting Non-Organ Confined Disease in Patients with Clinical T1/T2 Urothelial Carcinoma of the Bladder
Condition: Genitourinary
Intervention:

CLINICAL TRIAL 50399
Mechanisms of Functional Heterogeneity of Tumor Associated Macrophages in Glioblastoma
Condition: Neurologic Oncology
Intervention:

CLINICAL TRIAL 21446
Gut Microbiome/Metabolome in Durable Immunotherapy Responders- a Signature That Could Predict and Improve Cancer Treatment Outcomes
Condition: Head & Neck
Intervention:

Grants
  • Core Clinical Centers for Blood and Marrow Transplant Clincial Trials Network
    Sponsor: Nat Institutes of Health
    PI:Pidala, J.
  • The Mechanism of PV-10 in Regression of Solid Tumors
    Sponsor: Provectus Pharmaceuticals, Inc.
    PI:Pilon-Thomas, S.
  • Defining the Transplantation Tolerance Transcriptome: A Path Toward Individualized Management of Immune Suppression After Allogeneic Hematopoietic Cell Transplantation
    Sponsor: Nat Marrow Donor Program
    PI:Pidala, J.
  • Production Assistance for Cellular Therapies (PACT) - Cell Processing Facilities
    Sponsor: Nat Institutes of Health
    PI:Landin, A.
  • Correcting the Anti-HER-2 CD4 Th1 Response in Breast Cancer Therapy to Prevent Recurrence
    Sponsor: US Army
    PI:Czerniecki, B.,CO-PI:Soliman, H.
  • Tumor Infiltrating Lymphocyte Adoptive T Cell Therapy for NSCLC
    Sponsor: Stand Up To Cancer
    PI:Haura, E.
  • Targeting Immunosuppressive Cancer Associated Fibroblasts and Immune Checkpoints in NSCLC
    Sponsor: Florida Biomedical Research Program (FBRP)
    PI:Gray, J.
  • Augmenting T Cell Trafficking and Functionality through Novel Combinations of Epigenetic Agents and PD-1 Blockade
    Sponsor: Nat Institutes of Health
    PI:Beg, A.
  • Pediatric Clinical Research - Cutaneous
    Sponsor: V Fdtn for Cancer Research
    PI:Sondak, V.
  • Development of CAR-T/CER-T Therapies for Ovarian Cancer
    Sponsor: Certainty Therapeutics, Inc.
    PI:Conejo-Garcia, J.
  • Regulatory Dendritic Cells in Cancer
    Sponsor: Nat Institutes of Health
    PI:Conejo-Garcia, J.
  • Defining Impact of HDAC Inhibitors on Tumor Immunogenicity, T Cell Functionality and PD-1 Blockade Response in NSCLC Patients
    Sponsor: US Army
    PI:Beg, A.
  • Regulation of dendritic cell function and tumor immunity by TIM-3
    Sponsor: Nat Institutes of Health
    PI:Ruffell, B.
  • Study to Determine the Efficacy of the Protein X to Induce Acute Lymphoblastic Leukemia in Humanized Mice Model as Compared to Control
    Sponsor: 1 Voice Foundation
    PI:Sahakian, E.
  • B Cell-dependent Anti-tumor Immunity in Ovarian Cancer
    Sponsor: Nat Institutes of Health
    PI:Conejo-Garcia, J.
  • Functional reprogramming of tumor-MDSC through antibody-based therapies Targeting Notch Ligands
    Sponsor: Nat Institutes of Health
    PI:Rodriguez, P.
  • Novel Immunotherapy for Brain-Metastatic Breast Cancer
    Sponsor: US Army
    PI:Czerniecki, B.
  • Targetable Epidgenetic Mechanism Driving Cutaneous T Cell Lymphoma
    Sponsor: Nat Institutes of Health
    PI (Contact):Conejo-Garcia, J.,PI (MPI):Pinilla, J.,PI (MPI):Sokol, L.
  • Understanding the influence of bone-metastatic prostate cancer and mesenchymal stromal cells on γδ T cells, in the bone microenvironment.
    Sponsor: Nat Institutes of Health
    PI:Abate Daga, D.
  • The impact of donor gamma delta T-cell reconstitution and expression of leukemic cell ligands on immune escape and relapse of AML after allogeneic hematopoietic cell transplantation
    Sponsor: Tampa Community Foundation
    PI:Bejanyan, N.
  • Targeting T-cell costimulation and cytokine activation to prevent GVHD and preserve GVL
    Sponsor: Nat Institutes of Health
    PI:Pidala, J.
  • Donor gamma delta T-cell infusion for treatment of high-risk leukemia
    Sponsor: Florida Biomedical Research Program (FBRP)
    PI:Bejanyan, N.
  • Targeting poor-risk relapsed NonHodgkin Lymphoma subtypes
    Sponsor: Tampa Community Foundation
    PI (MPI):Pinilla, J.
  • Promoting an Effective Immune Response in Lymphoma
    Sponsor: US Army
    PI:Lazaryan, A.
  • Engineering and efficacy of biologics against HPV oncoproteins
    Sponsor: Nat Institutes of Health
    PI (Contact):Pilon-Thomas, S.,PI (MPI):Enderling, H.
  • HDAC6 inhibition and Treg-targeting as immunotherapeutic strategy for Non-small cell lung cancer
    Sponsor: Amer Lung Assoc
    PI:Adeegbe, D.
  • Phase I/II Study of CD8-Reduced T Cells for Treatment of Myelodysplastic Syndrome or Acute Myeloid Leukemia IND17305-(12/30/2016)
    Sponsor: US Food & Drug Administration
    PI:Elmariah, H.
  • FVIII TCR-Engineered T-Reg Cell Product
    Sponsor: Nat Institutes of Health
    PI:Landin, A.
  • Breast cancer immunotherapy with anti-TIM-3
    Sponsor: US Army
    PI:Ruffell, B.
  • Adrenergic modulation of cellular immune functions in CAR T cell–induced cytokine release syndrome
    Sponsor: Nat Institutes of Health
    PI:Davila, M.
  • Precision Interception of Aggressive Prostate Cancer In African American Men
    Sponsor: Nat Institutes of Health
    PI:Rounbehler, R.
  • Role of Sirt2 in T Cell Metabolism
    Sponsor: Nat Institutes of Health
    PI:Kim, S.
  • Ustekinumab for Graft vs Host Disease Prevention (IND 144540)
    Sponsor: US Food & Drug Administration
    PI (MPI):Pidala, J.
  • Exploiting the Immune Mapping of the Tumor Microenvironment to Improve Immunotherapy of Melanoma
    Sponsor: Adelson (Miriam & Sheldon) Medical Res Fdtn
    PI:Mulé, J.
  • Research Collaboration focused on cytokine analyses and immune phenotype/correlative analyses
    Sponsor: Precigen
    PI:Davila, M.
  • Treatment Free Remission After Combination Therapy with Ruxolitinib Plus Tyrosine Kinase Inhibitors in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation
    Sponsor: Incyte, Inc.
    PI:Pinilla, J.
  • Determine the effects of the TP-0184 and its derivatives (second generation) on myeloid-derived suppressor cell (MDSC)-mediated suppressive functions and improve the local bone marrow (BM) microenvironment in patients with MDS
    Sponsor: Tolero Pharmaceuticals
    PI (Contact):Wright, K.,PI:Eksioglu, E.
  • Intellia Research Collaboration - Project 1: Advancing Neoantigen-Specific T Cells
    Sponsor: Intellia Therapeutics
    PI:Pilon-Thomas, S.,CO-PI:Abate Daga, D.
  • A Phase II Biomarker Trial of CC-122 in Combination with Nivolumab in Advanced Melanoma
    Sponsor: Celgene Corp.
    PI:Pilon-Thomas, S.
  • Notch signaling boosts T cell-based immunotherapy
    Sponsor: Florida Biomedical Research Program (FBRP)
    PI:Rodriguez, P.,CO-PI:Luca, V.
  • Clinical investigation to improve efficacy of CAR-T Cell Therapy for Large B Cell Lymphoma
    Sponsor: Leukemia & Lymphoma Society
    PI:Locke, F.
  • Compartmentalized and Systemic Interactions of the Skin Microbiome in Cancer Immunotherapy Response
    Sponsor: The Jackson Laboratory
    PI:Markowitz, J.
  • MIDAS: Microangiopathy, endothelial Damage in Adults undergoing Stem cell transplantation
    Sponsor: Nat Institutes of Health
    PI:Bejanyan, N.
  • A Phase 2 Study to Assess the Efficacy, Safety, Pharmacokinetic Parameters, and Pharmacodynamics of TGR-1202 (Umbralisib) in Treatment Naïve Patients with Chronic Lymphocytic Leukemia (CLL)
    Sponsor: TG Therapeutics
    PI:Pinilla, J.
  • Correlative Studies for MCC 19197
    Sponsor: Bristol Myers Squibb Company
    PI:Brayer, J.
  • Immune Modulation by TIM-3
    Sponsor: Tesaro, Inc.
    PI:Ruffell, B.
  • Characterization of Evolving Immune Profiles of Marrow-Infiltrating Lymphocytes Engineered to Express a BCMA-Targeting Chimeric Antigen Receptor
    Sponsor: WindMIL Therapeutics
    PI:Brayer, J.
  • Myst/Turnstone– Moffitt Collaboration - Melanoma & Colorectal
    Sponsor: Turnstone Biologics
    PI (Contact):Pilon-Thomas, S.,CO-PI:Beatty, M.,CO-PI:Fleming, J.,CO-PI:Teer, J.,CO-PI:Mulé, J.
  • Predictive Markers and Evolutionary Dynamics of Axicabtagene Ciloleucel in NHL patients
    Sponsor: Kite Pharma
    PI:Locke, F.
  • Severe ER stress limits the efficacy of promising CAR-T cell treatments
    Sponsor: Kite Pharma
    PI:Locke, F.
  • Regulation of Zbtb44-Eomes complex in CD8+T cells and anti-tumor immunity
    Sponsor: Nat Institutes of Health
    PI:Davila, M.
  • Development of Expanded Access Criteria for Adoptive Cell Therapy in Soft Tissue Sarcoma
    Sponsor: Ocala Royal Dames
    PI:Mullinax, J.
  • Close Assessment and Testing for Chronic Graft-versus-Host Disease (The CATCH Study)
    Sponsor: Nat Institutes of Health
    PI:Pidala, J.
  • THE CANCER EPITOPE DATABASE AND ANALYSIS RESOURCE
    Sponsor: Nat Institutes of Health
    PI:Conejo-Garcia, J.
  • A low cost topical immunotherapy formulation suitable for treating cervical cancer in low- and middle- income countries and low resource settings in the U.S.
    Sponsor: Nat Institutes of Health
    PI:Pilon-Thomas, S.
  • Identification of biomarkers to predict the development of immune-related adverse events in patients treated with Tisagenlecleucel
    Sponsor: Novartis Pharmaceuticals Corp.
    PI:Davila, M.
  • Investigating the prognostic role of intrinsic immune evasion mechanisms in HNSCC
    Sponsor: Nat Institutes of Health
    PI:Wang, X.
  • Dissecting the immunological mechanisms associated with prostate cancer progression in African-American men and exploring epigenetics-based immune modulation for therapy
    Sponsor: Nat Institutes of Health
    PI:Adeegbe, D.
  • NSG Mouse Models to Evaluate the Efficacy of TIL
    Sponsor: Iovance Biotherapeutics
    PI:Pilon-Thomas, S.
  • Altered Tumor-Immune Synapse in Merkel Cell Carcinoma Drives Immune Evasion
    Sponsor: Moffitt Cancer Center
    PI:Kim, S.
  • Tumor infiltrating B-cells and Melanoma TIL
    Sponsor: Moffitt Cancer Center
    PI:Abate Daga, D.,CO-PI:Pilon-Thomas, S.
  • Role of Bcl11b in CD4+ T Cells and Innate Lymphoid Cells
    Sponsor: Nat Institutes of Health
    PI:Avram, D.
  • Tolerogenic Dual Microparticle System for Treatment of Multiple Sclerosis
    Sponsor: Nat Institutes of Health
    PI (MPI):Avram, D.
  • CD19 CAR-T Plus Elicio Amphiphile Combination Therapy
    Sponsor: Elicio Therapeutics
    PI:Davila, M.
  • High throughput screening assays to identify chemical probes targeting Hectd3, an E3 ubiquitin ligase
    Sponsor: Nat Institutes of Health
    PI (MPI):Avram, D.
  • Overcoming Resistance in HER2 Breast Cancer through a Novel Immunotherapy Approach
    Sponsor: Florida Biomedical Research Program (FBRP)
    PI:Czerniecki, B.
  • Predicting the Quality of Response to Specific Treatments (PQRST)
    Sponsor: Nat Institutes of Health
    PI:Pidala, J.
  • Association of gut microbiome with pathological complete response after immune based or standard neoadjuvant therapy in Breast cancer
    Sponsor: Moffitt Cancer Center
    PI:Czerniecki, B.
  • Bile acids restrict functional reprogramming of myeloid-derived suppressor cells in tumor beds
    Sponsor: Nat Institutes of Health
    PI:Rodriguez, P.
  • Validating and tailored targeting of identified immune signature in the tumors of African-American Prostate cancer patients
    Sponsor: Mike Slive Foundation
    PI:Adeegbe, D.
  • Study to develop a predictive model of immune-related adverse events in patients treated with axicabtagene ciloleucel
    Sponsor: Kite Pharma
    PI:Davila, M.,CO-PI:Faramand, R.
  • Sociome: Integrating Social Determinants of Health and Multi-Omic Data to Predict Cancer Prognosis
    Sponsor: Nat Institutes of Health
    PI:Wang, X.
  • Identifying tumor-intrinsic resistance mechanisms in melanoma patients upon treatment with immunotherapy.
    Sponsor: Adelson (Miriam & Sheldon) Medical Res Fdtn
    PI:Hwu, P.
  • Implementation of a Tailored Mobile Application to Improve Clinical Trial Engagement in Breast Cancer Patients
    Sponsor: V Fdtn for Cancer Research
    PI:Soliman, H.,CO-PI:Armaghani, A.
  • Actionable cell stress mechanisms governing αb and gd T cell responses against ovarian cancer
    Sponsor: Moffitt Cancer Center
    PI (Contact):Conejo-Garcia, J.,CO-PI:Rodriguez, P.,CO-PI:Tworoger, S.
  • Metabolic cooperation between macrophages and prostate cancer cells as a mechanism of resistance
    Sponsor: Moffitt Cancer Center
    PI:Ruffell, B.
  • Identifying Antigenic Mechanisms of Response and Resistance to Tumor‐infiltrating Lymphocytes in Stage 4 Non‐small Cell Lung Cancer
    Sponsor: Cancer Research Institute
    PI:Creelan, B.
  • Developing an Oncolytic Virus to induce de novo T cell priming: impact on TIL generation and therapeutic efficacy
    Sponsor: Moffitt Cancer Center
    PI:Beg, A.
  • Role of Butyrophilins in Regulating T-Cell Activity
    Sponsor: Moffitt Cancer Center
    PI:Conejo-Garcia, J.
  • Mechanisms of functional heterogeneity of tumor associated macrophages in glioblastoma
    Sponsor: Ivy (Ben & Catherine) Fdtn
    PI:Veglia, F.
  • Exploratory and IND-enabling Preclinical Studies to Assess Pharmacology and Safety of Anti-BCMA γδ2 CAR-T cells Using In vitro and In vivo Models for the Treatment of Multiple Myeloma
    Sponsor: Bluebird Bio Inc
    PI (Contact):Abate Daga, D.
  • Predictors of Immunotherapeutic Benefits in Patients with Advanced Malignancies Treated with Immune Checkpoint Inhibitors
    Sponsor: Tampa Community Foundation
    PI (Contact):Tarhini, A.
  • Preclinical studies of MEM-288
    Sponsor: Memgen
    PI:Beg, A.
  • Integrated transcriptome-based prognostic and disease monitoring strategies in childhood AML
    Sponsor: Amer Cancer Society
    PI:Shaw, T.
  • Tech Transfer support and clinical protocol development for the use of TIL in patients with melanoma
    Sponsor: Turnstone Biologics
    PI:Pilon-Thomas, S.,CO-PI:Mulé, J.
  • A phase I study of PI3K inhibitor Duvelisib in combination with oral Azacytidine in relapse/refractory mature T cell lymphoma.
    Sponsor: Secura Bio
    PI:Pinilla, J.
Publications
  • Mandriani B, Pelle' E, Pezzicoli G, Strosberg J, Abate-Daga D, Guarini A, Cives M, Porta C. Adoptive T-cell immunotherapy in digestive tract malignancies: Current challenges and future perspectives. Cancer Treat Rev. 2021 Nov.100:102288. Pubmedid: 34525422.
  • Broman KK, Bettampadi D, Pérez-Morales J, Sun J, Kirichenko D, Carr MJ, Eroglu Z, Tarhini AA, Khushalani N, Schabath MB, Sarnaik A, Sondak VK, Zager JS. Surveillance of Sentinel Node-Positive Melanoma Patients Who Receive Adjuvant Therapy Without Undergoing Completion Lymph Node Dissection. Ann Surg Oncol. 2021 Nov.28(12):6978-6985. Pubmedid: 34363118.
  • Bhatt VR, Wang T, Chen K, Kitko CL, MacMillan ML, Pidala JA, Malki MMA, Badawy SM, Beitinjaneh A, Ganguly S, Hamilton B, Hildebrandt GC, Lekakis LJ, Liu H, Maziarz RT, Modi D, Murthy HS, Preussler JM, Sharma A, Spellman SR, Arora M, Lee SJ. Chronic Graft-Versus-Host Disease, Non-Relapse Mortality and Disease Relapse in Older versus Younger Adults Undergoing Matched Allogeneic Peripheral Blood Hematopoietic Cell Transplantation: A CIBMTR Analysis. Transplant Cell Ther. 2021 Oct. Pubmedid: 34637965.
  • Aydin AM, Reich RR, Cao B, Cheriyan SK, Hajiran A, Zemp L, Yu A, Poch MA, Sexton WJ, Li R, Gilbert SM. Clinical indications for necessary and discretionary hospital readmissions after radical cystectomy. Urol Oncol. 2021 Oct. Pubmedid: 34629281.
  • Alfonso JCL, Grass GD, Welsh E, Ahmed KA, Teer JK, Pilon-Thomas S, Harrison LB, Cleveland JL, Mulé JJ, Eschrich SA, Torres-Roca JF, Enderling H. Tumor-immune ecosystem dynamics define an individual Radiation Immune Score to predict pan-cancer radiocurability. Neoplasia. 2021 Oct.23(11):1110-1122. Pubmedid: 34619428. Pmcid: PMC8502777.
  • Sharma MD, Pacholczyk R, Shi H, Berrong ZJ, Zakharia Y, Greco A, Chang CS, Eathiraj S, Kennedy E, Cash T, Bollag RJ, Kolhe R, Sadek R, McGaha TL, Rodriguez P, Mandula J, Blazar BR, Johnson TS, Munn DH. Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity. Immunity. 2021 Oct.54(10):2354-2371.e8. Pubmedid: 34614413. Pmcid: PMC8516719.
  • Kim MC, Borcherding N, Ahmed KK, Voigt AP, Vishwakarma A, Kolb R, Kluz PN, Pandey G, De U, Drashansky T, Helm EY, Zhang X, Gibson-Corley KN, Klesney-Tait J, Zhu Y, Lu J, Lu J, Huang X, Xiang H, Cheng J, Wang D, Wang Z, Tang J, Hu J, Wang Z, Liu H, Li M, Zhuang H, Avram D, Zhou D, Bacher R, Zheng SG, Wu X, Zakharia Y, Zhang W. CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells. Nat Commun. 2021 Oct.12(1):5764. Pubmedid: 34599187.
  • Gaballa S, Pinilla-Ibarz J. BTK Inhibitors in Chronic Lymphocytic Leukemia. Curr Hematol Malig Rep. 2021 Oct. Pubmedid: 34599723.
  • Engelhard V, Conejo-Garcia JR, Ahmed R, Nelson BH, Willard-Gallo K, Bruno TC, Fridman WH. B cells and cancer. Cancer Cell. 2021 Oct.39(10):1293-1296. Pubmedid: 34597591.
  • Green E, Li R. Editorial Comment. J Urol. 2021 Oct.206(4):883-884. Pubmedid: 34378970.
  • Chakiryan NH, Dahmen A, Bandini M, Pederzoli F, Marandino L, Albersen M, Roussel E, Zhu Y, Ye DW, Ornellas AA, Catanzaro M, Hakenberg OW, Heidenreich A, Haidl F, Watkin N, Ager M, Chahoud J, Briganti A, Salvioni R, Montorsi F, Necchi A, Spiess PE. Reply by Authors. J Urol. 2021 Oct.206(4):969. Pubmedid: 34379451.
  • Li R, Jain RK, Sexton WJ. Re: Andrea Necchi, Laura Marandino, Daniele Raggi, et al. Is it Time to Consider Eliminating Surgery from the Treatment of Locally Advanced Bladder Cancer? Eur Urol 2021;79:713-6. Eur Urol. 2021 Oct.80(4):e99. Pubmedid: 34364728.
  • Lazaryan A, Lee SJ. Reply to A. Heine et al. J Clin Oncol. 2021 Oct.39(29):3308-3309. Pubmedid: 34347529.
  • Reid S, Haddad D, Tezak A, Weidner A, Wang X, Mautz B, Moore J, Cadiz S, Zhu Y, Zheng W, Mayer IA, Shu XO, Pal T. Impact of molecular subtype and race on HR+, HER2- breast cancer survival. Breast Cancer Res Treat. 2021 Oct.189(3):845-852. Pubmedid: 34331630. Pmcid: PMC8511072.
  • Westin JR, Kersten MJ, Salles G, Abramson JS, Schuster SJ, Locke FL, Andreadis C. Efficacy and safety of CD19-directed CAR-T cell therapies in patients with relapsed/refractory aggressive B-cell lymphomas: Observations from the JULIET, ZUMA-1, and TRANSCEND trials. Am J Hematol. 2021 Oct.96(10):1295-1312. Pubmedid: 34310745.
  • Yang G, Yuan Z, Ahmed K, Welsh EA, Fulp WJ, Gonzalez RJ, Mullinax JE, Letson D, Bui M, Harrison LB, Scott JG, Torres-Roca JF, Naghavi AO. Genomic identification of sarcoma radiosensitivity and the clinical implications for radiation dose personalization. Transl Oncol. 2021 Oct.14(10):101165. Pubmedid: 34246048. Pmcid: PMC8274330.
  • Sondak VK, Messina JL. What's new in pediatric melanoma and Spitz tumors? Pretty much everything. Cancer. 2021 Oct.127(20):3720-3723. Pubmedid: 34228362.
  • Wolff D, Radojcic V, Lafyatis R, Cinar R, Rosenstein RK, Cowen EW, Cheng GS, Sheshadri A, Bergeron A, Williams KM, Todd JL, Teshima T, Cuvelier GDE, Holler E, McCurdy SR, Jenq RR, Hanash AM, Jacobsohn D, Santomasso BD, Jain S, Ogawa Y, Steven P, Luo ZK, Dietrich-Ntoukas T, Saban D, Bilic E, Penack O, Griffith LM, Cowden M, Martin PJ, Greinix HT, Sarantopoulos S, Socie G, Blazar BR, Pidala J, Kitko CL, Couriel DR, Cutler C, Schultz KR, Pavletic SZ, Lee SJ, Paczesny S. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report. Transplant Cell Ther. 2021 Oct.27(10):817-835. Pubmedid: 34217703. Pmcid: PMC8478861.
  • Chakiryan NH, Dahmen A, Bandini M, Pederzoli F, Marandino L, Albersen M, Roussel E, Zhu Y, Ye DW, Ornellas AA, Catanzaro M, Hakenberg OW, Heidenreich A, Haidl F, Watkin N, Ager M, Chahoud J, Briganti A, Salvioni R, Montorsi F, Necchi A, Spiess PE. Patterns of Recurrence following Inguinal Lymph Node Dissection for Penile Cancer: Optimizing Surveillance Strategies. J Urol. 2021 Oct.206(4):960-969. Pubmedid: 34032492.
  • Chakiryan NH, Jiang DD, Gillis KA, Green E, Hajiran A, Hugar L, Zemp L, Zhang J, Jain R, Chahoud J, Poch M, Manley BJ, Li R, Sexton W, Gilbert SM. Pathological Downstaging and Survival Outcomes Associated with Neoadjuvant Chemotherapy for Variant Histology Muscle Invasive Bladder Cancer. J Urol. 2021 Oct.206(4):924-932. Pubmedid: 34032503.
  • Hahn AW, Chahoud J, Campbell MT, Karp DD, Wang J, Stephen B, Tu SM, Pettaway CA, Naing A. Pembrolizumab for advanced penile cancer: a case series from a phase II basket trial. Invest New Drugs. 2021 Oct.39(5):1405-1410. Pubmedid: 33770291.
  • Landin AM, Cox C, Yu B, Bejanyan N, Davila M, Kelley L. Expansion and Enrichment of Gamma-Delta (γδ) T Cells from Apheresed Human Product. J Vis Exp. 2021 Sep.(175). Pubmedid: 34633380.
  • Davila ML, Bachmeier C. Advances in CAR T cell clinical development. Best Pract Res Clin Haematol. 2021 Sep.34(3):101307. Pubmedid: 34625229.
  • Showalter LE, Czerniecki BJ, Kodumudi K, Koski GK. Murine Dendritic Cells Grown in Serum-Free Culture Show Potent Therapeutic Activity when Loaded with Novel Th Epitopes in an Orthotopic Model of HER2pos Breast Cancer. Vaccines (Basel). 2021 Sep.9(9). Pubmedid: 34579275. Pmcid: PMC8473293.
  • Orellana-Noia VM, Reed D, McCook AA, Sen JM, Barlow CM, Malecek MK, Watkins MP, Kahl BS, Spinner MA, Advani R, Voorhees TJ, Snow A, Grover NS, Ayers AA, Romancik J, Liu Y, Huntington SF, Chavez JC, Saeed H, Lazaryan A, Raghunathan V, Spurgeon SE, Ollila TA, Del Prete C, Olszewski A, Ayers EC, Landsburg DJ, Echalier B, Lee J, Kamdar M, Caimi PF, Fu T, Liu J, David KA, Alharthy H, Law JY, Karmali R, Shah HR, Stephens DM, Major A, Rojek AE, Smith SM, Yellala A, Kallam A, Nakhoda S, Khan N, Sohail MA, Hill BT, Barrett-Campbell O, Lansigan F, Switchenko JM, Cohen JB, Portell CA. Single-route CNS prophylaxis for aggressive non-Hodgkin lymphomas: real-world outcomes from 21 US academic institutions. Blood. 2021 Sep. Pubmedid: 34570876.
  • Shadman M, Pasquini MC, Ahn KW, Chen Y, Turtle CJ, Hematti P, Cohen JB, Khimani F, Ganguly S, Merryman RW, Yared JA, Locke FL, Ahmed N, Munshi P, Beitinjaneh A, Reagan P, Herrera AF, Sauter CS, Kharfan-Dabaja MA, Hamadani M. Autologous Transplant versus Chimeric Antigen Receptor T-cell Therapy for Relapsed DLBCL in Partial Remission. Blood. 2021 Sep. Pubmedid: 34570879.
  • Miles BA, McMullen CP, Sweeny L, Zenga J, Li R, Divi V, Jackson R, Patel UA, Richmon JD. Practice patterns of virtual surgical planning: Survey of the reconstructive section of the American Head and Neck Society. Am J Otolaryngol. 2021 Sep.43(1):103225. Pubmedid: 34571439.
  • Menghrajani K, Gomez-Arteaga A, Madero-Marroquin R, Zhang MJ, Bo-Subait K, Sanchez J, Wang HL, Aljurf M, Assal A, Bacher U, Badawy SM, Bejanyan N, Bhatt VR, Bredeson CN, Byrne M, Castillo P, Cerny J, Chhabra S, Ciurea SO, DeFilipp Z, Farhadfar N, Gadalla SM, Gale RP, Ganguly S, Gowda L, Grunwald MR, Hashmi S, Hildebrandt GC, Kanakry CG, Kansagra A, Khimani F, Krem M, Lazarus HM, Liu H, Martino R, Michelis FV, Nathan S, Nishihori T, Olsson RF, Reshef R, Rizzieri D, Rowe JM, Savani BN, Seo S, Sharma A, Solh M, Ustun C, Verdonck LF, Hourigan CS, Sandmaier BM, Litzow MR, Kebriaei P, Weisdorf DJ, Zhang Y, Tallman MS, Saber W. Risk classification at diagnosis predicts post-HCT outcomes in intermediate-, adverse-risk, and KMT2A-rearranged AML. Blood Adv. 2021 Sep. Pubmedid: 34551064.
  • Jaishankar D, Cosgrove C, Ramesh P, Mahon J, Shivde R, Dellacecca ER, Yang SF, Mosenson J, Guevara-Patiño JA, Le Poole IC. HSP70iQ435A to subdue autoimmunity and support anti-tumor responses. Cell Stress Chaperones. 2021 Sep.26(5):845-857. Pubmedid: 34542825. Pmcid: PMC8492854.
  • Pidala J, Onstad L, Martin PJ, Hamilton BK, Cutler CS, Kitko CL, Carpenter PA, Chen GL, Arora M, Flowers ME, Arai S, Alousi A, White J, Jacobsohn DA, Pusic I, Lee SJ. Initial therapy of chronic graft vs. host disease: Analysis of practice variation and failure-free survival. Blood Adv. 2021 Sep. Pubmedid: 34535015.
  • Subramanian S, Han G, Olson N, Leong SP, Kashani-Sabet M, White RL, Zager JS, Sondak VK, Messina JL, Pockaj B, Kosiorek HE, Vetto J, Fowler G, Schneebaum S, Han D. Regression in melanoma is significantly associated with a lower regional recurrence rate and better recurrence-free survival. J Surg Oncol. 2021 Sep. Pubmedid: 34535899.
  • DeFilipp Z, Alousi A, Pidala J, Carpenter PA, Onstad L, Arai S, Arora M, Cutler CS, Flowers ME, Kitko CL, Chen GL, Lee SJ, Hamilton BK. Non-relapse mortality among patients diagnosed with chronic GVHD: An updated analysis from The Chronic GVHD Consortium. Blood Adv. 2021 Sep. Pubmedid: 34521116.
  • Chin KK, Kim HT, Inyang EA, Ho V, Koreth J, Romee R, Gooptu M, Shapiro R, Antin J, Soiffer R, Jaglowski S, Pidala J, Cutler C. Ibrutinib in Steroid-Refractory Chronic Graft-versus-Host Disease, a Single-Center Experience. Transplant Cell Ther. 2021 Sep. Pubmedid: 34481113.
  • Schoenbeck KL, Atallah E, Lin L, Weinfurt KP, Cortes J, Deininger MWN, Kota V, Larson RA, Mauro MJ, Oehler VG, Pinilla-Ibarz J, Radich JP, Schiffer CA, Shah NP, Silver RT, Thompson JE, Flynn KE. Patient-Reported Functional Outcomes in Patients with Chronic Myeloid Leukemia after Stopping Tyrosine Kinase Inhibitors. J Natl Cancer Inst. 2021 Sep. Pubmedid: 34491344.
  • de la Iglesia JV, Slebos RJC, Martin-Gomez L, Wang X, Teer JK, Tan AC, Gerke TA, Aden-Buie G, van Veen T, Masannat J, Chaudhary R, Song F, Fournier M, Siegel EM, Schabath MB, Wadsworth JT, Caudell J, Harrison L, Wenig BM, Conejo-Garcia J, Hernandez-Prera JC, Chung CH. Correction: Effects of Tobacco Smoking On the Tumor Immune Microenvironment in Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2021 Sep.27(17):4941. Pubmedid: 34470812.
  • Broman KK, Bettampadi D, Pérez-Morales J, Sun J, Kirichenko D, Carr MJ, Eroglu Z, Tarhini AA, Khushalani N, Schabath MB, Sarnaik A, Sondak VK, Zager JS. ASO Visual Abstract: Surveillance of Sentinel Node-Positive Melanoma Patients Who Receive Adjuvant Therapy Without Undergoing Completion Lymph Node Dissection. Ann Surg Oncol. 2021 Sep. Pubmedid: 34471988.
  • Neelapu SS, Locke FL, Bartlett NL, Lekakis LJ, Reagan P, Miklos DB, Jacobson CA, Braunschweig I, Oluwole OO, Siddiqi T, Lin Y, Crump M, Kuruvilla J, Van Den Neste EW, Farooq U, Navale L, DePuy V, Kim JJ, Gisselbrecht C. Comparison of 2-year outcomes with CAR T cells (ZUMA-1) versus salvage chemotherapy in refractory large B-cell lymphoma. Blood Adv. 2021 Sep. Pubmedid: 34478487.
  • Zhang Y, Seminario-Vidal L, Varnadoe C, Lu Y, Dong N, Salamanca C, Whiddon S, Bennett J, Hargis R, Liu H, Montejo M, Hussaini M, Harro C, Messina J, Benson K, Pinilla-Ibarz J, Conejo-Garcia J, Sokol L. Clinical characteristics and prognostic factors of 70 patients with Sézary syndrome: a single-institutional experience at Moffitt cancer center. Leuk Lymphoma. 2021 Sep.1-8. Pubmedid: 34467825.
  • Munshi PN, Hamadani M, Kumar A, Dreger P, Friedberg JW, Dreyling M, Kahl B, Jerkeman M, Kharfan-Dabaja MA, Locke FL, Shadman M, Hill BT, Ahmed S, Herrera AF, Sauter CS, Bachanova V, Ghosh N, Lunning M, Kenkre VP, Aljurf M, Wang M, Maddocks KJ, Leonard JP, Kamdar M, Phillips T, Cashen AF, Inwards DJ, Sureda A, Cohen JB, Smith SM, Carlo-Stella C, Savani B, Robinson SP, Fenske TS. American Society of Transplantation and Cellular Therapy, Center of International Blood and Marrow Transplant Research, and European Society for Blood and Marrow Transplantation Clinical Practice Recommendations for Transplantation and Cellular Therapies. Transplant Cell Ther. 2021 Sep.27(9):720-728. Pubmedid: 34452722. Pmcid: PMC8447221.
  • Kochat V, Raman AT, Landers SM, Tang M, Schulz J, Terranova C, Landry JP, Bhalla AD, Beird HC, Wu CC, Jiang Y, Mao X, Lazcano R, Gite S, Ingram DR, Yi M, Zhang J, Keung EZ, Scally CP, Roland CL, Hunt KK, Feig BW, Futreal PA, Hwu P, Wang WL, Lazar AJ, Slopis JM, Wilson-Robles H, Wiener DJ, McCutcheon IE, Wustefeld-Janssens B, Rai K, Torres KE. Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state. Acta Neuropathol. 2021 Sep.142(3):565-590. Pubmedid: 34283254.
  • Rollison DE, Amorrortu RP, Zhao Y, Messina JL, Schell MJ, Fenske NA, Cherpelis BS, Giuliano AR, Sondak VK, Pawlita M, McKay-Chopin S, Gheit T, Waterboer T, Tommasino M. Cutaneous Human Papillomaviruses and the Risk of Keratinocyte Carcinomas. Cancer Res. 2021 Sep.81(17):4628-4638. Pubmedid: 34266893. Pmcid: PMC8416805.
  • Frank MJ, Hossain NM, Bukhari A, Dean E, Spiegel JY, Claire GK, Kirsch I, Jacob AP, Mullins CD, Lee LW, Kong KA, Craig J, Mackall CL, Rapoport AP, Jain MD, Dahiya S, Locke FL, Miklos DB. Monitoring of Circulating Tumor DNA Improves Early Relapse Detection After Axicabtagene Ciloleucel Infusion in Large B-Cell Lymphoma: Results of a Prospective Multi-Institutional Trial. J Clin Oncol. 2021 Sep.39(27):3034-3043. Pubmedid: 34133196.
  • Amorrortu RP, Zhao Y, Messina JL, Schell MJ, Fenske NA, Cherpelis BS, Sondak VK, Giuliano AR, Pawlita M, McKay-Chopin S, Gheit T, Waterboer T, Tommasino M, Rollison DE. Association between Human Polyomaviruses and Keratinocyte Carcinomas: A Prospective Cohort Study. Cancer Epidemiol Biomarkers Prev. 2021 Sep.30(9):1761-1764. Pubmedid: 34187857. Pmcid: PMC8419098.
  • Li R, Zhang J, Gilbert SM, Conejo-Garcia J, Mulé JJ. Using oncolytic viruses to ignite the tumour immune microenvironment in bladder cancer. Nat Rev Urol. 2021 Sep.18(9):543-555. Pubmedid: 34183833.
  • DeFilipp Z, Couriel DR, Lazaryan A, Bhatt VR, Buxbaum NP, Alousi AM, Olivieri A, Pulanic D, Halter JP, Henderson LA, Zeiser R, Gooley TA, MacDonald KPA, Wolff D, Schultz KR, Paczesny S, Inamoto Y, Cutler CS, Kitko CL, Pidala JA, Lee SJ, Socie G, Sarantopoulos S, Pavletic SZ, Martin PJ, Blazar BR, Greinix HT. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: III. The 2020 Treatment of Chronic GVHD Report. Transplant Cell Ther. 2021 Sep.27(9):729-737. Pubmedid: 34147469.
  • Li R. Editorial Comment. J Urol. 2021 Sep.206(3):567. Pubmedid: 34121428.
  • Inamoto Y, Martin PJ, Onstad LE, Cheng GS, Williams KM, Pusic I, Ho VT, Arora M, Pidala J, Flowers MED, Gooley TA, Lawler RL, Hansen JA, Lee SJ. Relevance of Plasma Matrix Metalloproteinase-9 for Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplantation. Transplant Cell Ther. 2021 Sep.27(9):759.e1-759.e8. Pubmedid: 34126278. Pmcid: PMC8403632.
  • Cornelius LA, Fields RC, Tarhini A. Multidisciplinary Care of BRAF-Mutant Stage III Melanoma: A Physicians Perspective Review. Oncologist. 2021 Sep.26(9):e1644-e1651. Pubmedid: 34080754. Pmcid: PMC8417868.
  • Cortes A, Perez A, Bachmeier C, Mhaskar R, Chavez JC, Shah B, Nishihori T, Khimani F, Lazaryan A, Davila ML, Locke FL, Jain MD. Outcomes of CD19 Chimeric Antigen Receptor T Cell Therapy in Patients with Gastrointestinal Tract Involvement of Large B Cell Lymphoma. Transplant Cell Ther. 2021 Sep.27(9):768.e1-768.e6. Pubmedid: 34077811. Pmcid: PMC8403629.
  • Plaks V, Rossi JM, Chou J, Wang L, Poddar S, Han G, Wang Z, Kuang SQ, Chu F, Davis RE, Vega F, Bashir Z, Jacobson CA, Locke FL, Reagan P, Rodig SJ, Lekakis LJ, Flinn IW, Miklos DB, Bot A, Neelapu SS. CD19 target evasion as a mechanism of relapse in large B-cell lymphoma treated with axicabtagene ciloleucel. Blood. 2021 Sep.138(12):1081-1085. Pubmedid: 34041526. Pmcid: PMC8462361.
  • Percival ME, Wang HL, Zhang MJ, Saber W, de Lima M, Litzow M, Kebriaei P, Abdel-Azim H, Adekola K, Aljurf M, Bacher U, Badawy SM, Beitinjaneh A, Bejanyan N, Bhatt V, Byrne M, Cahn JY, Castillo P, Chao N, Chhabra S, Copelan E, Cutler C, DeFilipp Z, Dias A, Diaz MA, Estey E, Farhadfar N, Frangoul HA, Freytes CO, Gale RP, Ganguly S, Gowda L, Grunwald M, Hossain N, Kamble RT, Kanakry CG, Kansagra A, Kharfan-Dabaja MA, Krem M, Lazarus HM, Lee JW, Liesveld JL, Lin R, Liu H, McGuirk J, Munker R, Murthy HS, Nathan S, Nishihori T, Olsson RF, Palmisiano N, Passweg JR, Prestidge T, Ringdén O, Rizzieri DA, Rybka WB, Savoie ML, Schultz KR, Seo S, Sharma A, Solh M, Strair R, van der Poel M, Verdonck LF, Yared JA, Weisdorf D, Sandmaier BM. Correction to: Impact of depth of clinical response on outcomes of acute myeloid leukemia patients in first complete remission who undergo allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2021 Sep.56(9):2319. Pubmedid: 34017072. Pmcid: PMC8450771.
  • Chin JL, Lavi A, Metcalfe MJ, Siddiqui K, Dewar M, Petros FG, Li R, Nogueras González GM, Wang X, Nair SM, Ward JF, Pisters L. Long-Term Outcomes of Whole Gland Salvage Cryotherapy for Locally Recurrent Prostate Cancer following Radiation Therapy: A Combined Analysis of Two Centers. J Urol. 2021 Sep.206(3):646-654. Pubmedid: 33908799.
  • Petros FG, Choi W, Qi Y, Moss T, Li R, Su X, Guo CC, Czerniak B, Dinney C, McConkey DJ, Matin SF. Expression Analysis of Same-Patient Metachronous and Synchronous Upper Tract and Bladder Urothelial Carcinoma. J Urol. 2021 Sep.206(3):548-557. Pubmedid: 33881933.
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