Health Outcomes and Behavior

The Health Outcomes and Behavior (HOB) Program contributes to the prevention, detection, and control of cancer through the study of health-related behaviors, health care practices, and health-related quality of life. Work toward this goal involves research across the disease spectrum - from prevention and detection through to survivorship or advanced disease.

To accomplish its goal, the Program has four Specific Aims

Aim 1: Understand the determinants of health behaviors that can lead to prevention and early detection of cancer and develop effective methods of promoting those behaviors.
Much of the progress in reducing cancer mortality has occurred via improvements in prevention and screening behaviors. A major focus of the program is in the control of tobacco, with recent research expanding into the emerging area of electronic nicotine delivery systems (e.g., e-cigarettes). With regard to detection, efforts focus on interventions to increase cancer screening, primarily for colorectal cancer, but also to educate men to enable informed screening decisions on prostate cancer. Finally, program members seek to address the poor uptake of the FDA-approved HPV vaccine, especially in our catchment area.

Aim 2: Understand and improve the quality of life of patients and family members throughout the disease course.
A second goal of the program is to conduct research to understand and develop interventions to address common and distressing quality of life issues in patients during and after completion of active cancer treatment. In addition, Program members are leaders in addressing the emerging issues of fertility preservation among adolescent and young adult patients as well as quality of life of family caregivers of cancer patients.

Aim 3: Contribute to the evidence base, and synthesis of evidence, regarding delivery of cancer care and clinical outcomes.
Program members have been in the forefront of efforts to monitor and improve the quality of cancer care, in addition to studying the delivery of cancer care more generally. Moreover, they contribute to research syntheses in the form of systematic reviews and meta-analyses that underlie comparative effectiveness research and provide the empirical foundation of evidence-based clinical practice. Reflecting the growing importance of cancer care delivery research, this area is targeted for future growth of the program. 

Aim 4: Understand and intervene upon the social, cultural, and behavioral determinants of cancer-related health disparities.
There is growing awareness of the disparities that occur across the cancer continuum, including prevention, incidence, diagnosis, treatment, and outcomes. These disparities occur with respect to sex, gender-identity, race, ethnicity, socio-economic status, and other patient characteristics. To understand and address these disparities, program members conduct community-based participatory research throughout the catchment area. Moreover, during the previous funding period, program members have translated their earlier observational research into numerous ongoing randomized controlled trials of interventions designed to reduce a range of cancer-related health disparities.

Health Outcomes and Behavior Program Members

Program Leader:
Thomas H. Brandon, PhD

Members:
Lodovico Balducci, MD
Benjamin Djulbegovic, MD, PhD
Kristine A. Donovan, PhD, MBA
David J. Drobes, PhD
David Evans, PhD
Martine Extermann, MD, PhD
Scott M. Gilbert, MD
B. Lee Green, PhD
Clement K. Gwede, PhD, MPH, RN
Heather S. Jim, PhD
Cecile A. Lengacher, RN, PhD
Dinorah Martinez Tyson, PhD, MPH, MA
Susan C. McMillan, PhD, RN, FAAN
Cathy D. Meade, PhD, RN, FAAN
Teresita Munoz-Antonia, PhD
Gwendolyn P. Quinn, PhD
Maija Reblin, PhD 
Richard G. Roetzheim, MD, MSPH
Julian Sanchez, MD
Vani Nath Simmons, PhD
Brent J. Small, PhD
Marilyn Stern, PhD
Steve K. Sutton, PhD
Susan Thomas Vadaparampil, PhD, MPH
Christine Vinci, PhD

Collaborator Members:
Daniel Anaya, MD
Alicia Best, PhD, MPH
Margaret Booth-Jones, PhD
Julio Chavez Jiminez, MD
Ellen Daley, PhD
Michael Fradley, MD
Ming Ji, PhD
Peter Johnstone, MD, MA
Michael Poch, MD
Carmen Rodriguez, PhD, ARNP, AOCN
Tawee Tanvetyanon, MD, MPH
Lora Thompson, PhD
Hsiao-Lan Wang, PhD