Available Technologies Search

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19MB053 - VIDEO

Machine Learning: A Rapid and Non-invasive Lung Cancer Diagnostic to Predict PD-L1 Status Using Deep Learning Radiomics

21MB083

TILs: aAPCs that expresses an anti-CD3 scFv transmembrane to determine the cytotoxicity of TILs

19MA030N

Life Science Tool: Diazirine Reagents as Single and Double Nitrogen Transfer Reagents for Decarboxylative Amination

19MB040N

Math Model: A Radiomics Based Diagnostic to Predict Treatment Outcomes in Lung Cancer

21MA047N

Antibodies: Novel Targeted Nanobodies Against HPV E6/E7 to treat HPV Related Cancers

21MA019N

Diagnostic: Kits and Methods for Performing an ELISPOT to Detect Coronavirus

20MB040N

Protein Diagnostic: Diagnostic to detect Leptomeningeal Disease

19MB052T2

Companion Diagnostic to Predict Response to Immunotherapy Based on the Methylation Status

15MA034

Med Device: An Improved Pigtail Drainage Catheter for Percutaneous Fluid Aspiration

15MA033

Software: Negative Information Storage Model for Genomic Data

19MA037N

Math Model: A Diagnostic that Predicts Efficacy and Progression Free Survival in CAR-T Treated Patients

21MA028N

MDSC: Method of using Oral-L-Fucose to reduce immunosuppressive effect of Myeloid Derived Suppressor Cells (MDSCs)

14MA004N

Software: Real-time Visualization Software Enables Surgeons to “see-through” the patient and remove tumors more effectively

19MA034N

Math Model: A Diagnostic for Lesion Heterogeneity Classification for Informed Treatment Decision

21MA004N

Novel JAK2 Inhibitor Piperadine Aniline Derivatives of Ruxolitinib to Treat Myelofibrosis

21MA020N

BRD4 JAK2: Sultam (cyclic sulfonamide) BRD4 JAK2 Inhibitors to Treat Myelofibrosis

19MA019 - VIDEO

Software: Deep Neural Network to Locate and Label Brain Tumors Enables Surgeons to Remove Tumors More Effectively

19MB052 - VIDEO

Methylation Status Diagnostic: Diagnostic to Predict Response to Immunotherapy

13MA025

Software: An Automated Mammographic Density Measure for Improved Breast Cancer Screening

13MB053

Software: BMT Research Analysis Information Network (BRAIN)

21MA018

CD40 Agonist Improves ex-vivo TIL Expansion for Immunotherapy

18MB083N

Math Model: Predict Patient-Specific Radiotherapy Responses Using a Proliferation Saturation Index in an Adaptive Bayesian Approach

21MA008N

Human ITAM Mutated Variants For Better Intracellular Signaling Domains For Gamma-Delta CAR T-Cell Activation

20MB056

TROLLS: Inhibition Of TAp63 Regulated Oncogenic Long Noncoding RNAs (TROLLs) for the Treatment Of Cancer

14MB067N

Med Device: Expandable Intervertebral Cage for Spinal Fusion

20MB046T2

CMG Helicase: Novel Replicative CMG Helicase Inhibitors (CMGi) to Treat Solid Tumors

14MA022

Software: A Quantitative Framework to Identify Radiation Targets for Cancer Treatment that Synergize with Immunotherapy

17MA025

Genetic Biomarker: PTEN Loss of Expression as a Biomarker Response to GGTI-2418 Treatment

17MB044

Genetic Signature: Gene Signature to Distinguish between Metastatic Urothelial Carcinoma and Squamous Cell Carcinoma (Primary Lung and Metastatic Head & Neck)

05B141

Research Tool: Improved Electroporation Buffer for Enhanced Efficiency and Viability

20MB050N

Bispecific Gamma Delta CAR-T Cells that Recognize CD33, CD123 and NKG2D Ligands for the Treatment of Acute Myeloid Leukemia

18MA012N

Software: A Pathologist Tool for Alignment of Serial Whole Slide Histology Images

20MB037N

TAF1: Novel TAF1 Inhibitors for the Treatment of Cancer

18MB076

β-catenin/TCF: Small Molecule Peptidomimetic Inhibitors of the Interaction of β-catenin and T-cell Factor

19MB055 - VIDEO

β-catenin/BCL9: Novel Small Molecules that Inhibit the β-catenin/BCL9 Interaction in Breast Cancer

16MB066

miRNA Diagnostic: MicroRNA Signature to Predict Progression of Barrett’s Esophagus to Esophageal Dysplasia or Adenocarcinoma

16MB044

Molecular Imaging Probe: Novel IDO1-Targeting Cancer Diagnostic PET Imaging Agent

19MB064N

CDK12/CDK13: Novel Small Molecule Dual Inhibitors for CDK12/CDK13 for the Treatment of Triple Negative Breast Cancer

20MA013N

TILs: 12 Chemokine Gene Expression Signature to Increase the Efficacy of Manufacturing Tumor Infiltrating Lymphocytes

20MA016N

HER-2: Combination Therapy of a HER2-DC1 Dendritic Cell Cancer Vaccine and a Probiotic

17MB051

XBP-1: XBP-1 Inhibitor B-I09 for the Treatment of Acute GVHD and Solid Organ Rejection

17MA014

β-catenin/BCL-9: Small Molecules that Inhibit the β-catenin/BCL9 Interaction

15MB065

Protein Biomarker: Diagnostic for Progression of MDS to AML Using PD-1 or PD-L1 Expression

19MB049N

Fucose Increases Tumor Cell HLA-DRB1 Expression Increasing CD4+ T-cell Activation with Synergistic Tumor Killing Activity with anti-PD1 Checkpoint Inhibitors

17MB056N

Ubiquitin Bispecific Antibody: Antibodies that Bring the E3 Ubiquitin Ligase into Close Proximity to Receptors to Induce the Receptor’s Degradation

19MB066T2

N-Terminal Mutant PGC-1α Overexpression Enhances Metabolic Fitness Reducing CAR-T Exhaustion while Maintaining Proliferative Capacity

15MB042N

Molecular Imaging Probe: In vivo Positron Emission Tomography-Based Perfusion/Blood Pool Imaging Using Labeled Erythrocytes

15MA031N

Diagnostic: S100A9 Serum Concentration Levels Predict Lenalidomide Response Duration

19MB048N

Antibodies: Fully Human anti-BDNF Antibodies

15MA015

Molecular Imaging: Monoacylated TLR2 Ligand Fluorescent Probe for Detecti

15MA011

Ras: Small Molecules that Inhibit Mutant KRAS

19MA033N

EGFR, MUC1: Bispecific CAR-T Cell constructs (chimeric antigen receptors) that Recognize EGFR and MUC1 for the Treatment of Lung Cancer

19MA035N

T-bet: T-bet Transcription Factor Armed CAR-T Cells Maintain Memory Phenotypes and Rescue CD4 Cells Leading to Increased Persistence

16MA023N

HDAC, BTK: Method of Using HDAC Inhibitors, Alone or in Combination with BTK Inhibitors, for Treating Chronic Lymphocytic Leukemia (CLL)

14MA052N

Genetic Signature: Microarray-based Gene Expression Profiling to Predict Tumor Sensitivity to Radiotherapy

15MA021N

Diagnostic: Intracellular S100A9 Alone or NLRP3 Inflammasome Activation as MDS Biomarkers

16MA005N

Aurora/JAK2: Dual JAK2 and Aurora A Kinase Inhibitor for GVHD Prophylaxis

19MB047N

Antibodies: Fully Human anti-TSPAN7 Antibodies

19MA007

B-RAF: Combination Therapy of TILs and BRAF Inhibitors to Treat BRAF Inhibitor-Resistant Metastatic Melanoma

13MB055

Molecular Imaging: Novel Imaging Software Diagnostic to Determine Survival in Glioblastoma Multiforme

13MB047

Imaging: Decision Support Tool for Oncology Treatment that Analyzes Radiological Images

14MB069

BRD4 JAK2: Novel BRD4/JAK2 Dual Inhibitors as Cancer Therapeutics

12MB110

Anti-Infectives: Novel Symmetrical Marinopyrrole Derivative as a Therapeutic against Resistant Bacterial Strains

13MB054

Molecular Imaging: Texture Feature Analysis of Low-Dose CT Images for Pulmonary Nodule Diagnosis

14MB075N - VIDEO

YAP1/OCT4: Small Molecule Inhibitors of the Protein-protein Interaction of YAP1 and OCT4 to Treat Cancer

19MA015NT2

NKG2D-Ligand: Enhancing Carcinoma Infiltration by NKG2D-Ligand Targeted CAR-T Cells by Co-Expression of the Chemokine Receptor CX3CR1

19MA015N

GPC3: Enhancing Carcinoma Infiltration by Anti-GPC3 Targeted CAR-T Cells by Co-Expression of the Chemokine Receptor CX3CR1

12MA069

Genetic Signature: Gene Expression Signature to Determine the Benefit of Adjuvant Chemotherapy in Early Stage Non-Small Cell Lung Cancer

18MB059

Brain Mets: Lung Cancer Brain Metastases Targeting CAR-T Cell Constructs with Phage Display Derived Peptide Oligomers

12MB104

Molecular Imaging Probe: A Novel 18F Scaffold for Preparing Targeted PET Imaging Probess

18MB061

Antibodies: Fully Human anti-PD1 Antibodies

10MB083

Proteasome: Non-covalent and Reversible Proteasome Inhibitors with an Oxadiazole-isopropylamide Core

10MB048

FT/GGT: Novel Dual Inhibitor of Farnesyltransferase and Geranylgeranyltransferase-1 as an Anti-Cancer Agentbitor

18MB054

Glioma Stem Cell Targeting CAR-T Cell Constructs with Phage Display Derived Peptide Oligomers

12MA011N

Protein Diagnostic: Antigen based Biomarkers That Predict Response to Immunotherapy

18MA013

SSTR2: CAR-T cells to Kill Neuroendocrine Tumors Expressing Somatostatin Receptor 2

17MB042

CD99: Novel CD99 scFv Targeting CAR-T cells for Acute Myeloid Leukemia Immunotherapy

18MA023

NKG2D ligands: NKG2D Chimeric Antigen Receptor CAR-T Cells for Acute Myeloid Leukemia Immunotherapy

17MB048 - VIDEO

TILs: The Use of Fucose to Increase TILs for the Immunotherapy of Melanoma

09MA014

Genetic Signature: Immune-related Gene Signature to Influence Treatment Decisions and Predict Immunotherapy Outcomes in Cancer

10MA024

Molecular Imaging Probe: Breast Cancer-Targeted Probe Set for Improved Detection of Lymph Node Metastases

08MA005

Antibody Diagnostic: Monitoring Multiple Myeloma Progression and Recurrence

10MB069N

Molecular Imaging Probe: Fluorescent and MRI Targeted Probes for the Melanocortin Receptor 1 on Melanomas, and Micelle Complexes for Drug Delivery

18MA019N

aAPC: Artificial Antigen-Presenting Cells with Heparin-Binding Domain and Protein L for Producing CAR-T Cells

21MA031

Software: Cancer BERT Network (caBERTnet): A Question-and-Answer System to Extract Data from Free-Text Pathology Reports

22MA004N

Small Molecule Inhibitor: 3-(4-fluorophenyl)-N-phenylbenzamide Small-Molecule Inhibitors of the β-Catenin/BCL9 Protein-Protein Interaction

19MB057 13MB048 - VIDEO

Diagnostic for Predicting Response to Therapies in Multiple Myeloma

17MC003 - VIDEO

Copyright: Energize:mBC is a Web-based Program to Treat Fatigue in Metastatic Breast Cancer Patients

21MB061

KRAS: Platform Technology: Dimeric IgA Therapeutic Antibody for Intra-Tumoral Targeting of Mutant KRAS

21MA023

β-Catenin/BCL9: 1-Benzoyl 4-Phenoxypiperidines Small-Molecule Inhibitors of the β-Catenin/BCL9 Protein-Protein Interaction

21MA021N

p53: Combination Therapy of Hypothermia and Chemotherapy to Treat Temperature Sensitive p53 Mutant Tumors

19MA038N

Math Model: A Diagnostic that Predicts Treatment Outcome and Personalize CAR-T Therapies

20MA008N

Molecular Imaging Agent: A Novel Fluorescence Molecular Imaging Agent for Intraoperative Margin Assessment in Breast Cancer

21MB064

CLEC12A: Novel CLEC12A scFv Targeting CAR-T cells for Acute Myeloid Leukemia Immunotherapy

20MB046

HPV E1: Novel Use for Aminocoumarins as HPV Helicase E1 Inhibitors to Treat Cancer

12MB072

Software: Method for Improving the Accuracy of Charged Particle Beam (High Energy Proton or Carbon Ion Beam) Radiotherapy

20MB062 - VIDEO

Mutated Estrogen Receptor Neoantigen Peptide-Pulsed Type I Dendritic Cell (DC1) Vaccine Therapy to Treat Metastatic ER-positive Breast Cancer

18MB083N

Mathematical Modeling: Predict Patient-Specific Radiotherapy Responses Using a Proliferation Saturation Index in an Adaptive Bayesian Approach

20MB051N

β-Catenin/BCL-9: Acyl sulfonamide-containing Small Molecules that Inhibit the β-catenin/BCL9 Protein-Protein Interaction

20MB053N

Single-domain antibodies (nanobodies) targeting the notch ligand DLL4 to Disrupt the interaction of DLL4 and Notch1 for GVHD

18MB055N

Math Model: Methods for the Treatment of Prostate Cancer Using Intermittent Adaptive Therapy

18MB055N

Mathematical Modeling: Methods for the Treatment of Prostate Cancer Using Intermittent Adaptive Therapy

20MA024

CD33 CD123: Novel Bispecific CD33 CD123 scFv CAR-T Cells for Acute Myeloid Leukemia Immunotherapy

17MA001

miRNA Diagnostic: miRNA Signature for Non-invasive Early Detection of Malignancy in IPMN

13MB073

Software: Decision Support Tool for Oncology Treatment using Mathematical Simulations

20MA027 - VIDEO

Olfactory Receptor Targeting Chimeric Antigen Receptor Expressing T cell (CAR-T) for Solid Tumors

17MA002N

Molecular Imaging: Predicting Response to Adjuvant Ipilimumab Treatment in Melanoma Using a Novel Algorithm to Analyze Nitric Oxide Levels in Peripheral Blood Immune Cells

20MA015N

ACK1: Small molecule ACK1 Inhibitors for the Treatment of Castrate Resistant Prostate Cancer

10MA037N

Software: Improved Detection of Lung Function and Management of Lung Cancer Radio Therapy

18MB053

Novel BRD4/JAK2 Dual Inhibitor Cancer Therapeutics

19MB066

PGC-1α: CAR-T Cells with Enhanced Metabolic Fitness due to Co-expression of Mutant PGC-1α

20MA005 - VIDEO

PERK, IRE1: Method of Enhancing Immunotherapy Using ER Stress Pathway Inhibitors

20MA009

CAR-T: D99/CLEC12A AND gated Bispecific CAR-T for the Treatment of AML

16MB042

Protein Biomarker: Diagnostic to Determine which Low-Risk MDS Patients to Treat with Lenalidomide to Restore Sensitivity to Erythropoietin

16MB040

Genetic Signature: Gene Signature to Distinguish Lung Squamous Cell Carcinoma from Metastatic Head & Neck Squamous Cell Carcinoma

16MB041

Protein Biomarker: Method for Measuring MRE11 in Muscle –Invasive Bladder Cancer to Predict Chemoradiation Response Using AQUA

18MA018N

β-catenin/TCF: Small Molecule Inhibitors of the Interaction of β-catenin and T-cell Factor

13MB078

miRNA Diagnostic: Blood Based microRNA Assay to Detect Malignant Intraductal Papillary Mucinous Neoplasms (IPMNs)

14MB092

WEE1: Small Molecule WEE1 Inhibitor (WEIN-159) that Inhibits WEE1 Phosphorylation of H2B but Not Cdc2 to Treat Can

14MA001

Protein Biomarker: Expression of WEE1 and PAXIP1 Can Select Patients who Respond to WEE1 Inhibitor Therapys

15MA012

Ras/Raf: Stapled Peptides as Inhibitors of Mutant KRAS

14MB086N

HDAC, BTK: Method of Using HDAC Inhibitors, Alone or in Combination with BTK Inhibitors, for Treating Non-Hodgkin’s Lymphoma (NHL)

19MA029N

Bispecific T-Cell Engagers: B Cells Engineered to Express Bispecific T-Cell Engagers Result in Longer Half Lives

19MA022N

aAPC: Artificial Antigen-Presenting Cells Expressing NKG2D Ligands for Producing anti-NKG2D CAR-T Cells

19MA026N

NOTCH: Enhancing the Efficacy of Adoptive T-cell Immunotherapy Using Novel Notch Ligands

13MB056N

Molecular Imaging: PET Probes of Radiofluorinated Carboximidamides for IDO-Targeted Imaging

18MB078

TILs: Enhancing the anti-tumor immunity of TILs by inhibiting Sirt2

12MB089

IRE-1: Novel Small Molecule Inhibitors of IRE-1 for the Treatment of B-cell Cancer

13MA009

Multiplex Diagnostic: in Multiple Myeloma Using Detection of Minimal Residual Disease RNA Sequencing and Mass Spectrometry

13MA036

Genetic Signature: Gene Signature Predicts Recurrence and Benefit From Adjuvant Chemotherapy in Colorectal Cancer

13MA002

Protein Diagnostic: Phosphorylated STAT3 Protein as a Novel Biomarker of Graft Versus Host Disease

12MB098

STAT3: Novel Small Molecule STAT3 Inhibitor for Cancer Treatment

12MA035N

Mcl-1/Bcl-xL: Cyclic, Symmetrical and Asymmetrical Marinopyrroles as Anti-Cancer Agents

18MB072

18MB072 Method of Using anti-CD277 Antibodies to Treat Cancer

18MB062N

Antibodies: Fully Human anti-LAG3 Antibodies

11MB064

Molecular Imaging Probe: Synthetic Fluorescent Probe for Improved Detection and Tumor Removal in Pancreatic Cancer Patients

09MB048

pH: Method of Inhibiting Metastasis with Systemic Non-Volatile Buffers to Reduce Intratumoral pH

11MB069

Gene Signature for Immunotherapy Response Prediction in Cancer Based on Nuclear Factor-kappa B

18MB049N

Suicide Switch: CAR-T cells can be Designed to Self-Destruct if Patient shows signs of Toxicity including graft-vs.-host-disease, cytokine release syndrome (CRS), and neurotoxicty

18MB044N

Inflammasome: Method of Using Small-molecule Pyrin-domain Targeted NLRP3 Inflammasome Inhibitors to Neutralize Pyroptotic Cell Death Contributing to MDS Pathogenesis

18MB048N

TLR9 Ligand Trap: TLR9-IgG4 Fusion Protein to Neutralize Innate Immune Activation and Chronic Inflammation Contributing to MDS Pathogenesis

10MA019N

LPAAT: Lysophosphatidic Acid Acyltransferase-Beta Inhibitors to Treat Pancreatic Cancer

11MB087N

Protein Diagnostic: Mass Spectrometry Diagnostic for BRAF and Heat Shock Proteins

10MA018N

Mcl-1: Asymmetrical Marinopyrroles as Anti-Cancer Agents

18MA037 - VIDEO

PSCA: Targeting Gamma Delta CAR-T Cells for the Treatment of Bone Metastatic Castrate-Resistant Prostate Cancer

11MA022

Imaging: Digital Pathology Tool to Grade Breast Cancer Histological Images

18MA033

TILs: TILs modified with CAR constructs result in CAR-TILs for Cancer Therapy

11MA014

Protein Diagnostic: New Receptor Tyrosine Kinase Assay for Patient Treatment Selection Based on Protein-Protein Bindi

09MA037

Aurora: Novel Small Molecule Aurora A Kinase Inhibitor as a Cancer Therapeutic

09MA015

Rho Kinase (ROCK) Inhibitors as Anticancer Drugs

08MB014 10MB078

Topoisomerase II: Small Molecule Inhibitors of Nuclear Export of Topoisomerase II Alpha for Multiple Myeloma Treatment

18MA034N

TILs: Method of Using a Demethylating Agent to Enhance STING Expression and TIL Anti-Tumor Activity in Melanoma

11MA026N

Molecular Imaging Probe: Surrogate Markers for Colon Adenoma and Adenocarcinoma

17MB037

Inflammasome: Stapled Peptides NLRP3 Inflammasome Inhibitors to Neutralize Pyroptotic Cell Death Contributing to MDS Pathogenesis

17MA030T2 - VIDEO

CD33, CD123: Bispecific CAR-T Cell Constructs that Recognize CD33 and CD123 for the Treatment of Acute Myeloid Leukemia

17BM041

CLEC12A: Novel CLEC12A scFv Targeting CAR-T cells for Acute Myeloid Leukemia Immunotherapy

17MA012

TILs: Simple and Rapid Method for Culture of TILs from Melanoma Tumor Fragments or Core Needle Biopsies of Solid Tumors

16MB069

IL-13Rα2: Targeting Chimeric Antigen Receptor Expressing T cell (CAR-T) for Melanoma Immunotherapy

17MA007

CD3-CD28: Bispecific Antibody for the Generation of CAR-T cells for Cancer Immunotherapy

17MA030

CD33: CAR-T Cell Constructs that Recognize CD33 for the Treatment of Acute Myeloid Leukemia

17MA031

CD123: CAR-T Cell Constructs that Recognize CD123 for the Treatment of Acute Myeloid Leukemia

17MB042T2N

CD99 CLEC12A: Novel Bispecific CD99 CLEC12A scFv CAR-T Cells for Acute Myeloid Leukemia Immunotherapy

11MA052

Med Device: Improved Endotracheal Tube to Prevent Intubation-Related Complications Related to Airway Edema (Swelling)

13MA001

Med Device: Improved Enteral Feeding Tube and Retention Disc to Reduce Dislodgement, Infection and Complications

20MA021

A Single Customizable and Adaptive Ventilator Device to Treat Multiple Patients

16MA021

Med Device: An Improved Stylet for Endotracheal Tube Placement

19MA010

Med Device: Drug Infusion 'The Snowflake' Device for Treatment of Brain Cancer

18MB047

Med Device: Biopsy Needle with Internal Ridges that Lead to a Higher Tissue Specimen Retrieval Rate

10MB054

Med Device: Handheld Radioisotope Identification Device (RIID)

11MA021

Med Device: Minimally Invasive Spinal Fusion Using a Transdiscal Screw System

11MA017N

Med Device: Pump-assisted High Flow Rate Isolated Limb Infusion for Regional Cancer Treatment

11MA021T2

Med Device: Bidirectional Expandable Intervertebral Cages for Spinal Fusion

10MB065N

Med Device: Muscle Stapler

16MA001

TIM3 Ligand Trap: TIM-3-IgG4 Fusion Protein for the Treatment of Anemia in Low- or Intermediate (Int)-risk MDS Patients

14MB098

Cancer Vaccine: Full-Length Variant Survivin Vaccine Potentiates Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma

16MA025

TLR9: Targeting Chimeric Antigen Receptor-Expressing T cell (CAR-T) for MDS and AML Immunotherapy

16MB050

AaPC: Artificial Antigen-Presenting Cells for Expanding TILs and MILs in Cancer Immunotherapy

16MB049

aAPC: Artificial Antigen-Presenting Cells expressing CD3, CD28 and a Heparin-Binding Domain for Producing CAR-Ts

16MA028N

TLS: Method of Using Chitosan Hydrogels with Chemokine-Releasing Microparticles or Stromal Cells to Bioengineer Tertiary Lymphoid Structures to Enhance the Immune System for Cancer Therapy

14MB100N

Bromodomain: Ex vivo Activation and Expansion of Antigen Specific T cells in the Presence of a Bromodomain Inhibitor

13MB041

S100A9: CD33/IgG1 Chimera Antibody Trap to Neutralize S100A9 to Treat MDS

07MB004

Antibodies: Use of Antibodies to MARCO for Enhanced Dendritic Cell Vaccine Efficacy

14MB072

TAG72-CD3: Bispecific T-Cell Engager for Targeted Cancer Immunotherapy

16MB057

TAG72: CAR-T Cell constructs (chimeric antigen receptors) that Recognize TAG72

11MA013

Vaccine: Vaccines Using Synthetic Peptide-Poly IC Complexes that Elicit T-cell Responses Comparable to Live Vaccination

14MA037N

HDAC6: Method of Using Histone Deacetylase 6 Inhibition for Enhancing T cell Function During Anti-Tumor Response and Tumor-Peptide Vaccination

14MA027N

HDAC: Method of Using Histone Deacetylase as a Modulator of PDL1 Expression and Activity

22MA027

CAR-T: CAR-T Constructs with NKG2D Receptor Signaling Domains