June 5, 2015

CAR T-Cell Therapy for Multiple Myeloma: Promising Signs of Efficacy
The Myeloma Beacon – June 4

These results represent an excellent proof of principal that we can engineer and grow T cells to effectively control multiple myeloma in patients with high-risk and highly aggressive disease,” Dr. Kenneth Shain, a myeloma specialist at the H. Lee Moffitt Cancer Center in Tampa, Florida, told The Beacon. CAR T-cell therapy is “a truly novel leap forward in the treatment of multiple myeloma and other types of cancer.”  Dr. Shain was not involved in the Penn study.

Gene Panel Confirms High Rate of BRCA Mutations
MedPage Today – June 3
In commenting on the study to MedPage Today, Amit Mahipal, MD, medical director of clinical research at the Moffitt Cancer Center in Tampa, Fla., said "we use these tests to help guide us in treating women with metastatic breast cancer. We may see something that we can find a drug that we can use. Sometimes we find rare mutations in breast cancer patients that we didn't expect to see."

Androgen deprivation therapy may lead to cognitive impairment in prostate cancer patients
Cancer Therapy Advisor – June 2

In this study, researchers from the Moffitt Cancer Center in Tampa, Florida, used formal tests to compare the cognitive ability of 58 patients receiving ADT for prostate cancer with 84 patients with prostate cancer who did not receive ADT and 88 men with no cancer. The men treated with ADT were 70% more likely to experience cognitive impairment at 6 months, and more than twice as likely to experience cognitive impairment at the 1-year time point.

New Lung Cancer Drug
WeAreCentralPa.com – June 1

Opdivo activates the immune system, causing it to attack the cancer cells. After several months of treatment, the cancer has shrunk, by 90 percent. Ben Creelan, MD, Assistant Faculty, Medical Oncologist at Moffitt Cancer Center in Tampa, Florida said, “It’s a real game changer to be able to have a treatment which works for years in some patients.”

Dr. Creelan Discusses Results of MEDI4736 in Combination With Getfitnib in NSCLC
OncLive – June 1
Ben Creelan, MD, medical oncologist with Moffitt Cancer Center, discusses the results from a phase I study of MEDI4736, an anti-PD-L1 antibody, in combination with gefitinib, an EGFR inhibitor, in patients with non-small-cell lung cancer (NSCLC).

Prostate cancer patients are more likely to die if they eat an unhealthy Western diet high in red meat, fat and 'white' carbs
Daily Mail – June 1, 2015
Active compounds found in green tea can help reduce a man's risk of developing prostate cancer, a study at the Moffitt Cancer Center has found.

ASCO Alternative Payment Model Would Compensate Docs for Personalized Medicine-related Services
GenomeWeb – May 31

"Most oncologists' offices do not store tissue from a patient's previous procedures or have the in-house expertise to perform biopsies for needed tissue," Howard McLeod, founding medical director of Moffitt's Personalized Medicine Institute, told GenomeWeb. "This requires coordination with pathology departments, arrangement with interventional radiology for a new biopsy, or similar efforts."

Scene and Heard
TBO.com – May 31

Dr. Frank Glass, a dermatology specialist at the Cutaneous Oncology Program at Moffitt Cancer Center, and Dr. Alexis Lipton of A Place for Women have new titles: 2015 Man and Woman of the Year.

A couple weds at charity cancer event, the ceremony deeply personal and pays it forward
ABC Action News – May 31
It dawned on the couple that the perfect setting would be the annual "Swim Across America event at Pier 60 in Clearwater. Both volunteer for the cancer fighting charity that benefits Moffitt Cancer Center, the cause is personal.

No need for Lymph Node Dissection in certain Melanoma patients
Cancer Network – May 30

“Today, we do not know which patients are already cured by their sentinel node biopsy procedure, which ones are destined to die no matter what surgery is done, and which ones might be saved from recurring and dying—or at least from extra surgical side effects—by early use of lymph node dissection,” said Vernon Sondak, MD, chair of the department of cutaneous oncology at the Moffitt Cancer Center & Research Institute in Tampa, Florida, who was not involved in the study.

Barefoot Bliss
Tampa Bay Times – May 30

Shawn Jolly and Alexandria Jolly spend a moment together after tying the knot at Clearwater Beach on Saturday. They were married after Swim Across America —Tampa Bay, an open water swimming event that benefits Moffitt Cancer Center.

Melanoma Treatment May Not Always Require Extensive Lymph Node Removal
HealthDay - May 30
However, patients with advanced melanoma likely will continue to need all of the surrounding lymph nodes removed, as that is a well-established strategy for improving their survival, said Dr. Vernon Sondak, chief of cutaneous oncology at the H. Lee Moffitt Cancer Center and Research Institute in Tampa, Fla.
"Surgery is critical in those more advanced cases," said Sondak, who was not involved in the new study.

Green Tea Could Help Prevent Prostate Cancer
Tech Times – May 30

Research in prostate cancer has recently focused on chemoprevention, which is the use of agents for the prevention of the disease. A research team led by Dr. Nagi Kumar from the Moffitt Cancer Center has released the results of a study showing the effectiveness of green tea in preventing prostate cancer.

CharleyWalters: Torri Hunter ‘pretty sure’ he’d accept extension from Twins
Twin Cities Pioneer Press – May 30

Ralph Jon Fritz, the popular former WCCO-TV sports personality, continues his fight with stage 4 stomach cancer at the Moffitt Cancer Center in Tampa, Fla.

Couple Says 'I Do' to Swim Across America, Each Other
Clearwater Patch – May 29

Shawn Jolly and Alexandria Reynolds are out to make a big splash with their upcoming wedding on Clearwater Beach. Swim Across America – Tampa Bay benefits the Moffitt Cancer Center directly.

Take a Dip to help fight skin cancer
WSTP – May 29

"This type of funding is really critical for us," says Moffitt surgeon and researcher Dr. Amod Sarnaik. "We're in a position where a lot of federal funding for research has really dropped off and we really appreciate the generosity of both Swim Across America and the Tampa Bay community that comes out."


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