April 10, 2015

Commentary | This one is easy: Make it Paul Maechtle Field at John Kiker Memorial Stadium
The Bradenton Herald – April 9
When the late Eric Robinson, a former Southeast teacher, was fighting cancer and needed help, Maechtle often drove him to the Moffitt Cancer Center in Tampa for his chemotherapy treatments.

Genetic variations linked to increased PCa risk identified
Urology Times – April 9
Men who have a family history of prostate cancer have a two-fold greater risk of developing the disease. Currently, approximately 100 genetic variants have been found to influence the risk of prostate cancer. However, these variants only account for 33% of increased familial risk, suggesting that additional genetic factors must also exist, according to a press release from Moffitt Cancer Center in Tampa, FL, which participated in the study.

Former Bishop’s star honored for service
U-T San Diego – April 8
Over the weekend in Tampa, Roeper joined other members of the Good Works Team in partnership with the Kay Yow Cancer Fund to visit the Moffitt Cancer Center.

Is Ipilimumab Ready for the Adjuvant Treatment of Melanoma?
Medscape – April 8
“Having made such dramatic progress in metastatic melanoma with ipilimumab and other new drugs, the next frontier is clearly adjuvant therapy. This study provides the first brick in a bigger wall by showing us that it is at least possible to use new, breakthrough drugs in the adjuvant setting,” Vernon K. Sondak, MD, from the Department of Cutaneous Oncology at the Moffitt Cancer Center in Tampa, Florida, who coauthored an accompanying comment with Grant A. McArthur, MB BS, from the Peter MacCallum Cancer Centre in Melbourne, Australia, told Medscape Medical News.

Generous Brandon grandmother needs help as she fights bone marrow cancer
The Tampa Tribune – April 8
If she went through with a “mismatched” bone marrow transplant at Moffitt Cancer Center in Tampa, she says her chance of survival is 40 percent. 

Pacritinib demonstrates safety, efficacy for patients with myelofibrosis
Hem/Onc Today – April 7
“Currently, myelofibrosis patients with anemia and thrombocytopenia have limited treatment options for splenomegaly and constitutional symptoms and these data show that pacritinib has potential to help patients who are sub-optimally managed on currently available treatments,” Rami S. Komrokji, MD, associate professor of oncologic sciences at the University of South Florida College of Medicine and clinical director of the department of malignant hematology at Moffitt Cancer Center, said in a press release.

Dr. Sotomayor on Personalized Medicine Preventing Cancer
OncLive – April 7
Eduardo Sotomayor, MD, the Susan and John Sykes Endowed Chair in Hematologic Malignancies at Moffitt Cancer Center, discusses how personalized medicine may eventually help with preventing cancer.

New Prostate Cancer Genetic Variants Identified In microRNAs
Prostate Cancer News Today – April 7
A group of scientists at the Moffitt Cancer Center participated in a study through the PRACTICAL consortium (short for Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) that intended to identify additional genetic variants associated with higher risk of prostate cancer development, as the current known genetic variations (approximately 100) only explain 33 percent of the increase risk in prostate cancer within families.

Local briefs: Bobcats honored, Nelson wins tourney
The Telegraph (Macon, Ga.) – April 7
Keys, the women’s program’s all-time leading scorer, participated in a community service project while on the trip. In partnership with the Kay Yow Cancer Fund, team members visited the Moffitt Cancer Center to assemble and distribute TLC backpacks to patients and families and participate in a special art project. They also distributed autographed basketballs to Moffitt patients.

UK Hoops Star Bria Goss Honored For Outstanding Community Service
Lex18.com – April 6
In addition to being honored, Goss and the Allstate WBCA Good Works Team members also teamed up with WNBA star and Good Works Team ambassador Tamika Catchings to take part in a community service project this morning while down in Tampa. In partnership with the Kay Yow Cancer Fund, Catchings and the Allstate WBCA Good Works Team made a visit to the Moffitt Cancer Center to assemble and distribute TLC backpacks to patients and families and participate in a special art project. They also distributed autographed basketball to Moffitt patients.

New designs released for Florida specialty license plates
Orlando Sentinel – April 6
The state currently has 123 specialty with the addition last month of a plate for Moffitt Cancer Center and has four others trying to reach 1,000 presales before production.

PHP may increase survival in patients with liver metastases
Healio.com – April 6
Jonathan S. Zager, MD, FACS, director of regional therapies and chair of graduate medical education at Moffitt Cancer Center in Tampa, and colleagues, including Andrea M. Abbott, MD, of surgical oncology at Moffitt Cancer Center, analyzed data of 30 patients with cutaneous or uveal melanoma that metastasized to the liver after treatment with percutaneous hepatic perfusion (PHP), yttrium-90 (Y90) or chemoembolization using melphalan hydrochloride for injection with the Delcath Hepatic Delivery System (Melphalan/HDS, Delcath Systems, Inc.). 

Oncology research network adds four new members
HemOnc Today – April 5
The Oncology Research Information Exchange Network, anchored by Moffitt Cancer Center and The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, recently added four new members.

Melanoma: Engineered Herpes Virus Effective in Treating Local and Distant Lesions

Oncology Times – April 3

Following the presentation, Vernon Sondak, MD, Chief of the Division of Cutaneous Oncology at H. Lee Moffitt Cancer Center, strongly advised during the question-and-answer period that the study results must be interpreted in light of the design of the study and patient inclusion criteria, including the endpoint, the control arm, patient selection, and the choice of patients with or without uninjected lesions: “All of these factors are so critical in, first of all, getting a successful trial and then subsequently figuring out where this kind of therapy fits into the management algorithm for our patients,” he said.

Nivolumab Increases Response Rate vs Chemotherapy in Advanced Melanoma With Progression After Anti–CTLA-4 Treatment
The ASCO Post – April 3
Jeffrey S. Weber, MD, of the Moffitt Cancer Center, is the corresponding author of The Lancet Oncology article.

New PHSC leader brings decades of experience
Tampa Bay Business Journal – April 3
Moffitt Cancer Center and Florida Hospital Wesley Chapel already are partners.

Rays: Roster turnover, Cash on other side of conversations
Tampa Bay Times – April 3
The Rays and Moffitt Cancer Center will offer free skin cancer screenings before today's game in Lot 7.

Digital pathology and the big Cs (that’s ‘cancer’ and ‘cloud’)
The Register – April 3
Proscia was founded in 2014 by five technologists, scientists, and entrepreneurs from Johns Hopkins, the Moffitt Cancer Center, The Ohio State University College of Medicine, and the University of Pittsburgh.

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