December 12, 2014

Evolutionary principles used to model cancer mutations and discover potential therapeutic targets
Oncology Nurse Advisor – Dec. 12
However, these researchers, with Moffitt Cancer Center in Tampa, Florida, modeled cancer progression on the premise that cancer cells live in an environment that has limited resources, such as space and nutrients. Like all living organisms, cancer cells must obey the laws of evolution, including trade-offs between proliferation and survival.

Novel Agent Reduces Need for Transfusion in MDS
Medscape – Dec. 11
After treatment with sotatercept (ACE-011, Acceleron Pharma and Celgene Corporation) — a first-in-class activin type 2A-receptor fusion protein — 45% of 54 evaluable MDS patients experienced either a reduction in the need for transfusions or an increase in hemoglobin levels, said lead author Rami S. Komrokji, MD, from the Moffitt Cancer Center in Tampa, Florida.

Builders take Island Cup, championship honors ‘Ace’
The Islander (Anna Maria) – Dec. 10
Hayward received a somewhat unexpected release from Moffitt Cancer Center in Tampa after a two-week stay, arriving at the community center soccer field to say hello to friends and for the unveiling of the new Paul “Ace” Hayward Island Cup, which will be awarded annually to the adult championship team.

Capt. Dave ‘Pop Pop’ Bogan Sr. Dies at 74
Point Pleasant Patch – Dec. 10
A funeral mass will be held at St. Sebastian Catholic Church on Dec. 27 at 11 a.m. In lieu of flowers, the Brogan family requests to please send a donation to the Visiting Nurse Association of The Treasure Coast, 1110 35th Lane, Vero Beach, FL 32960, or to Moffitt Cancer Center Foundation, PO Box 23827, Tampa FL 33623.

Novel Compound Targets Anemia in MDS
MedPage Today – Dec. 9
In a phase II dose-ranging study, sotatercept (also known as ACE-011) led to hematological improvement in nearly half of 54 evaluable patients who did not respond to erythropoiesis-stimulating agents, according to Rami Komrokji, MD, of Moffitt Cancer Center in Tampa, Fla., and colleagues.

How Safe are E-Cigarettes?
ENTtoday – Dec. 9
The lack of evidence-based data makes formulating recommendations on the use of e-cigarettes a thorny topic. Kristen Otto, MD, an otolaryngologist at the Moffitt Cancer Center in Tampa, Fla., can’t recommend the product to her patients.

Sotatercept alleviated anemia burden in low-risk myelodysplastic syndrome
HemOnc Today – Dec. 8
“Anemia is a common complication of myelodysplastic syndrome, one of the most common blood cancers in elderly patients,” Rami S. Komrokji, MD, of the department of malignant hematology at the H. Lee Moffitt Cancer Center and Research Institute, said during a press briefing.

Ivanhoe Broadcast News via WLS-TV (Chicago) – Dec. 6
Moffitt Cancer Center Doctor Jacob Gardinier Scott says finding ways to cope can be helpful for patients.

Creative coping improves cancer recovery
Ivanhoe Broadcast News via  WJXT (Jacksonville) – Dec. 4
Jacob Gardinier Scott, MD, Radiation Oncologist of Moffitt Cancer Center in Tampa says finding ways to cope can be helpful for patients.

Never Too Old to Fight Cancer
Scientific American – Nov. 18
“Most aging cells develop genomic changes that make them more susceptible to the carcinogens in the environment,” says oncologist Lodovico Balducci, who studies and treats cancer in the elderly at the Moffitt Cancer Center in Tampa, Fla. 


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