May 18, 2012

Dabrafenib Safe in Melanoma With Brain Mets
MedPage Today - May 18
"No previous systemic treatment has shown this degree of clinical activity against melanoma brain metastases, and dabrafenib was not predicted to cross the blood-brain barrier in substantial quantities," wrote Gibney and Sondak, who are from the H. Lee Moffitt Cancer Center and Research Institute in Tampa, Fla.

Unprecedented tarpon weekend may never recur
Gasparilla Gazette - May 18
The Gasparilla Island Kids Classic runs from 4:30 p.m. to 7:30 p.m. Capt. Sandy Melvin's event will benefit the Moffitt Cancer Center Institute.

Celebrating the Silver King: Get ready for some salty art, great food and Colton James this weekend
Boca Beacon - May 18
The event is sponsored by Capt. Sandy Melvin and Gasparilla Outfitters, and the proceeds of the tournament will benefit the H. Lee Moffitt Cancer & Research Institute and their "Families First" program.

Entre 2039 competidores Hispanos sobresalieron en Millas por Moffitt
7dias - May 18
Cuatro hombres y dos mujeres hispanas de diversas edades sobresalieron en los primeros lugares entre 2,039 competidores, 31 categorías y 5 millas de recorrido, en la séptima carrera anual que organiza la Fundación de Millas por Moffitt (Milles for Moffitt), la cual se efectuó exitosamente en los alrededores de la Universidad del Sur de la Florida (USF), el pasado sábado 12 de mayo.

Women Do Better Than Men after Melanoma Diagnosis
Daily Glow - May 17
"What was noteworthy about this study was that it was able to quantify how much better that prognosis was--about 30 percent better--by looking at the patients enrolled in melanoma clinical trials, where everyone is carefully followed," Vernon Sondak, chair of the department of cutaneous oncology at the Moffitt Cancer Center in Tampa, Fla., tells Daily Glow in an e-mail. 

Getting a Jump on Big News Stories to be presented at ASCO's 47th Annual Meeting
Oncology Business Review - May 17
Use of the combination significantly decreased skin toxicity compared with that associated with vemurafenib, said lead author Jeffrey Weber, MD, H. Lee Moffitt Cancer Center, Tampa, FL. For example, only 3% of patients developed squamous cell carcinomas compared with about 15% to 25% of patients treated with other BRAF inhibitors; another 5% developed actinic keratosis which is much lower than with a BRAF inhibitor alone, Dr. Weber commented. 

BRAF-Plus-MEK Inhibition Slows Melanoma
The Oncology Report - May 17
Overall, cutaneous squamous cell carcinoma occurred in 3% of patients, which compares favorably with a 15%-20% incidence with dabrafenib and other BRAF inhibitors, said Dr. Weber, director of the Donald A. Adam Comprehensive Melanoma Research Center at the Moffitt Cancer Center in Tampa.

'One-Two Punch' for Advanced Melanoma Is Less Toxic
Medscape - May 17
The combination of the BRAF inhibitor dabrafenib (GlaxoSmithKline) and the MEK inhibitor trametinib (GlaxoSmithKline) provided a median progression-free survival of 7.4 months in 77 patients, which is comparable to results from studies of single-agent vemurafenib (also a BRAF inhibitor), said lead study author Jeffrey Weber, MD, PhD, from the Moffitt Cancer Center in Tampa, Florida. 

Double-Barrel Tx Effective for Melanoma
MedPage Today - May 17
The combination caused fewer side effects than a BRAF inhibitor alone, Jeffrey S. Weber, MD, said during a press briefing in advance of the American Society of Clinical Oncology meeting, which begins May 31 in Chicago.

Cancer Fighting Collaboration
Medical News - May 17
The expert consortium included attendees from member universities' cancer programs at Emory University, Moffitt Cancer Center, Morehouse College, Ponce School of Medicine and Health Sciences, Tulane University, Tuskegee University, University of Alabama at Birmingham, UMMC, and Xavier University.

GSK melanoma drug shows promise in early trial
Reuters - May 17
In a commentary piece in The Lancet, Geoffrey Gibney and Vernon Sondak from the H Lee Moffitt Cancer Center and Research Institute in the U.S. described the results as "impressive" and "encouraging".

BRAF-Plus-MEK Inhibition Slows Melanoma
Skin and Allergy News - May 17
Moreover, there were fewer dermatologic side effects than with any BRAF inhibitor alone seen to date, Dr. Jeffrey S. Weber said during a press briefing in advance of the upcoming annual meeting of the American Society of Clinical Oncology.

Could GSK's melanoma therapy work better than Roche's Zelboraf?
MedCity News - May 17
Dr. Jeffrey Webber, an oncologist who led a clinical study on the GSK combination drug, said that progression-free survival, or PFS, in patients on the drug was 10.8 months.

Operating income slips for Moffitt, All Children's
Tampa Bay Business Journal - May 17
The three months ended March 31 were tough ones financially for H. Lee Moffitt Cancer Center & Research Institute    H. Lee Moffitt Cancer Center & Research Institute Latest from The Business Journals Chamber works to maximize RNC media opportunity Initiatives follow new directions post-downturn Biovest names Moffitt's James Mulé to new advisory board Follow this company and All Children's Hospital.

Glaxo's Melanoma Cocktail Slows Cancer in Study
Bloomberg - May 17
"Not only are the two drugs causing shrinkage of the cancer, but we're seeing that a second anti-cancer therapy may actually suppress the side effects of the first," said Jeffrey Weber, an oncologist at the H. Lee Moffitt Cancer Center in Tampa, Florida, in a statement.

Melanoma Drug Combo Packs a One-Two Punch
Science Magazine - May 16
That number is "impressive," said oncologist Jeffrey Weber of the Moffitt Cancer Center in Tampa, Florida, who presented the results today in a telephone and Web press conference.

Paddle against Cancer benefits research
Tampa Bay Newspapers Weekly - May 16
The second annual Paddle against Cancer event will benefit vital cancer research, education and patient care at Moffitt Cancer Center.

Glaxo melanoma drug combo shows promise in small trial
Reuters - May 16
Those patients saw median progression-free survival of 10.8 months, Dr Jeffrey Weber of the H. Lee Moffitt Cancer Center in Tampa, Florida, who is also the study's lead author, said at a news conference held by the American Society of Clinical Oncology.

I-Team: CEOs at tax-exempt Tampa Bay area medical institutions do well on pay day
ABC Action News - May 16
Rounding out the trio, William S. Dalton, president and CEO of the H. Lee Moffitt Cancer Center and Research Institute Inc., earned slightly more than $1 million for the same time period as Klasko's compensation.

Two-Drug Combo May Be Safe for Melanoma Treatment
HealthDay - May 16
"Not only are the two drugs causing shrinkage of the cancer, but we're seeing that a second anti-cancer therapy may actually suppress the side effects of the first," said Dr. Jeffrey Weber, director of the Donald A. Adam Comprehensive Melanoma Research Center at the H. Lee Moffitt Cancer Center, Tampa, Fla., in a news release from the American Society of Clinical Oncologists.

LVH and Wistar Institute to Study Cancer
Salisbury Patch - May 16
In February 2011, LVHN announced a partnership with the Moffitt Cancer Center and Research Institute of Tampa, Fla., to enable cancer patients to participate in advanced clinical research trials.

Lehigh Valley Health Network's latest partnership aims to study melanoma treatment
Lehigh Valley Live- May 16
In February 2011, the network unveiled an agreement with Moffitt Cancer Center and Research Institute, which is based in Tampa, Fla., at the campus of the University of South Florida.

Combining Two Targeted Therapies Stalls Disease Progression in Melanoma Patients With BRAF Mutations
OncLive - May 16
"We have to be cautious because of the small number of patients in this trial, but it looks extremely encouraging," said Jeffrey S. Weber, MD, PhD, director of the Donald A. Adam Comprehensive Melanoma Research Center at the H. Lee Moffitt Cancer Center and Research Institute in Tampa, Florida, and lead researcher on this study.

Bob Samuels honored for cancer education efforts
The Tampa Tribune - May 15
He was recognized for his efforts to educate others about cancer, specifically prostate cancer, during the recent PNC Bank Miles for Moffitt event at the University of South Florida Sun Dome.

Research Identifies Important Proteins that Play Role in Sarcoma Cancer Growth
EmaxHealth - May 15
These tyrosine kinases are the focus of new research for potential new treatments of sarcoma by scientists at Moffitt Cancer Center.

Lehigh Valley Health Network announces partnership for cancer research
The Morning Call - May 15
In February 2011, the health network made a similar pact with the Moffitt Cancer Center and Research Institute of Tampa, Fla., to provide an avenue for cancer patients to participate in advanced clinical research trials.

Taking action: Can Tampa's USF flex its horsepower surrounded by crumbling neighborhoods?
Tampa Bay Times - May 15
A group called the Innovation Alliance includes folks from USF, Florida Hospital, Busch Gardens and Moffitt Cancer Center -- heavyweights that have been in talks for the past year about what to do.

USF surrounding communities to get a makeover
The Oracle - May 14
The core group of partners will probably include the Innovation Alliance, which is a non-profit comprising USF, Moffitt Cancer Center, Busch Gardens and Florida Hospitals, Merrill said.

Compassionate use gives lifeline to needy patients
San Francisco Chronicle - May 14
The FDA authorized the request, and the drug maker shipped the drug to Moffitt Cancer Center in Tampa on April 25.

Study reveals variability in physician intentions and recommendations on HPV vaccination
News Medical Net - May 14
Researchers at Moffitt Cancer Center surveyed 1,008 physicians seeking their knowledge, recommendation beliefs and information on their practices regarding the controversial human papillomavirus (HPV) vaccine, which is aimed at preventing cancers resulting from sexually transmitted HPV infection.

'Visit Tampa Bay' would deliver tourism message
Tampa Bay Times - May 14
Kudos to Bob Samuels, who received the Priscilla Mack Survivorship Award at Saturday's Miles for Moffitt race.

Area around USF campus ripe for rebirth
The Tampa Tribune - May 13
Sharpe, who has a map of the university area on his office wall, never stopped thinking about the area and its proximity to important community assets: USF, the H. Lee Moffitt Cancer Center, Busch Gardens, Florida Hospital and the James A. Haley Veterans' Hospital.

PHOTO GALLERY: Thousands support Miles for Moffitt
WTSP-TV - May 12
Thousands of survivors, runners, and walkers all took part in the 7th Annual Miles for Moffitt Saturday, May 12 at the University of South Florida Sundome. It's estimated that 7,000 people attended.

Miles for Moffitt Under Way Today (May 12)
Brandon Patch - May 12
The Miles for Moffitt fundraiser to beat cancer will benefit from the "Ken-Ducky-Derby" fundraiser held at O'Brien's Irish Pub and restaurant in Brandon.

RNC provides Tampa Bay business recruiters with marketing opportunity
Tampa Bay Times - May 12
For example, someone from the H. Lee Moffitt Cancer Center & Research Institute could talk about Moffitt's work in personalized medicine.

Psychosocial Interventions Significantly Diminish Cancer-related Pain
Pain Medicine News - May 2012
After an exhaustive literature search, lead investigator Paul B. Jacobsen, PhD, associate director in the Division of Population Science, Moffitt Cancer Center, Tampa, Fla., selected 37 studies for the meta-analysis.

Meet The Rock Star Execs Of Healthcare
InformationWeek Healthcare - May 2012
In a similar vein, Mark Hulse, CIO at Moffitt Cancer Center and Research Institute, recently launched the organization's Health and Research Informatics platform, based on Oracle data warehouse and analytics software.

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