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CLINICAL TRIAL16914

Sickness Behaviors in Gynecologic Cancer Patients Treated with Chemotherapy

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL17263

Phase I Trial of ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17676

A Multi-Center Biologic Assignment Trial Comparing Reduced Intensity Allogeneic Hematopoietic Cell Transplant to Hypomethylating Therapy or Best Supportive Care in Patients Age 50 or Older with Intermediate-2 and High Risk Myelodysplastic Syndrome

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17799

A Phase I Dose Escalation Trial of Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of the Head and Neck

Cancer Type: Head & Neck

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CLINICAL TRIAL17933

A Randomized, Open-Label Study Comparing the Combination of YONDELIS and DOXIL/CAELYX With DOXIL/CAELYX Monotherapy for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL17929

A Phase I/II, Multicenter, Open-label, Dose Escalation and Randomized Trial of BI 836858 in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18190

A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Efficacy and Safety of Farletuzumab (MORAb-003) in Combination with Carboplatin plus Paclitaxel or Carboplatin plus Peglyated Liposomal Doxorubicin (PLD) in Subjects with Low CA125 Platinum-Sensitive Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18509

A Phase 3 Randomized, Double-blind, Multi-center Study of Adjuvant Nivolumab versus Placebo in Subjects with High Risk Invasive Urothelial Carcinoma

Cancer Type: Genitourinary

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CLINICAL TRIAL18435

Phase II study of Copanlisib (BAY 80-6946) in Combination with Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18390

A Phase 1 Dose Escalation, Multicenter, Open-Label, Safety, Pharmacokinetic and Pharmacodynamic Study of FT-1101 In Patients With Relapsed or Refractory Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18329

A Phase 1/2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Subjects with Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r ALL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18558

A Phase 1B/2 Open-Label Study to Evaluate Safety, Clinical Activity, Pharmacokinetics and Pharmacodynamics of Avelumab (MSB00100718C) in Combination with Other Cancer Immunotherapies in Patients with Advanced Malignancies

Cancer Type: Thoracic

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CLINICAL TRIAL18611

The Gut Microbiome and Immunotherapy in Non-small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL17773

A Phase 1 Study of the Safety and Pharmacokinetics of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects with Metastatic Urothelial Cancer and Other Malignant Solid Tumors that Express Nectin-4

Cancer Type: Genitourinary

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CLINICAL TRIAL18515

Symptoms, Toxicity Prevalence and Quality of Life Benefit of Targeted Therapies and Immunotherapies in Lung Cancer Patients: An Observational Prospective Cohort Study within the Total Cancer Care Population

Cancer Type: Thoracic

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CLINICAL TRIAL18684

A Phase II Investigator Sponsored Study of Nivolumab in Patients with Advanced Refractory Biliary Tract Cancers

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18612

A Randomized Phase II/III Study of Adjuvant Concurrent Radiation and Chemotherapy versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors

Cancer Type: Head & Neck

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CLINICAL TRIAL17865

SL-401 in Patients with Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasm

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18356

A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients who have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL18855

Multicenter, Open-label, Phase 1, Dose-escalation,Cohort-expansion, First-in-Human Study of KHK2455 Administered as Monotherapy and in Combination with Mogamulizumab (KW-0761) in Adult Subjects with Locally Advanced or Metastatic Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18386

A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL18755

A Phase 2, Randomized Study of MLN0128 (a Dual TORC1/2 Inhibitor), MLN0128 + MLN1117 (a PI3Ka Inhibitor), Weekly Paclitaxel, or the Combination of Weekly Paclitaxel and MLN0128 in Women With Advanced, Recurrent, or Persistent Endometrial Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18778

A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18814

A Multi-Center, Phase II Trial of HLA-Mismatched Unrelated Donor Bone Marrow Transplantation with Post-Transplantation Cyclophosphamide for Patients with Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18094

A Phase 2 Study of Transarterial Chemoperfusion Treatment with Cisplatin, Methotrexate and Gemcitabine in Patients with Unresectable Pleural Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL18847

Increasing HPV Vaccination Series Completion Rates among Adolescent Hispanics in Tampa and Ponce

Cancer Type: Healthy Subjects

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CLINICAL TRIAL18207

Phase 2 Trial of Dose Dense (Weekly) Paclitaxel with Pembrolizumab (MK-3475) in Platinum Resistant Recurrent Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18495

Caregiver Relationship Quality and Communication in Advanced Cancer Care

Cancer Type: Multiple

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CLINICAL TRIAL18068

A Multi-Center Phase 2 Open-Label Study to Evaluate Safety and Efficacy in Subjects with Melanoma Metastatic to the Brain treated with Nivolumab in Combination with Ipilimumab followed by Nivolumab Monotherapy

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18517

A Randomized, Open-Label, Active-Controlled, Phase II Study of Intravenous Anetumab Ravtansine (BAY 94-9343) or Vinorelbine in Patients with Advanced or Metastatic Malignant Pleural Mesothelioma Overexpressing Mesothelin and Progressed on First Line Platinum/Pemetrexed-Based Chemotherapy

Cancer Type: Thoracic

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CLINICAL TRIAL18837

An Open-Label Study of Rovalpituzumab Tesirine in Subjects with Delta-Like Protein 3-Expressing Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18821

A Phase 1b Trial to Assess the Modulation of Biological Markers in Patients with Potentially Resectable Soft Tissue Sarcoma Treated with Olaratumab Monotherapy Followed by Olaratumab plus Doxorubicin Combination Therapy

Cancer Type: Sarcoma

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CLINICAL TRIAL18828

Smartphone-Based Assessment of Patient-Reported Outcomes Related to Receipt of Immunotherapy

Cancer Type: Head & Neck

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CLINICAL TRIAL18772

A Randomized Multicenter, Open-label, Phase 2 Study Evaluating the Efficacy and Safety of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Subjects with Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly (>= 65 years) Acute Myeloid Leukemia (AML) Subjects Not Eligible for Hematopoietic Stem Cell Transplantation (HSCT)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18396

A Phase III Clinical Trial Evaluating TheraSphere® in Patients with Metastatic Colorectal Carcinoma of the Liver who have Failed First Line Chemotherapy

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18683

A Phase 3, Multinational, Randomized, Open-Label, Parallel-Arm Study of Avelumab (MSB0010718C) in Combination with Axitenib (INLYTA®) Versus Sunitinub (SUTENT®) Monotherapy in the First-Line Treatment of Patients with Advanced Renal Cell Carcinoma

Cancer Type: Genitourinary

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CLINICAL TRIAL18664

A Phase 2, Multi-Center Study of High Dose Chemotherapy with Autologous Stem Cell Transplant Followed by Maintenance Therapy with Romidepsin for the Treatment of T cell Non-Hodgkin's Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18825

A Phase 1b, First-in-Human, Dose Escalation and Expansion Study of XMT-1522 in Patients with Advanced Breast Cancer and Other Advanced Tumors Expressing HER2

Cancer Type: Multiple

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CLINICAL TRIAL18832

A Platform Study Exploring the Safety, Tolerability, Effect on the Tumor Microenvironment, and Efficacy of INCB Combinations in Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18878

A Single-Arm, Multicenter, Phase 2 Trial to Evaluate Efficacy and Safety of Lenvatinib in Combination with Everolimus in Subjects with Unresectable Advanced or Metastatic Non Clear Cell Renal Cell Carcinoma (nccRCC) Who Have Not Received any Chemotherapy for Advanced Disease

Cancer Type: Genitourinary

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CLINICAL TRIAL18527

Non-Comparative, Open-Label, Multiple Cohort, Phase 1/2 Study of Nivolumab Monotherpay and Nivolumab Combination Therapy in Subjects with Virus-Positive and Virus-Negative Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18527

Non-Comparative, Open-Label, Multiple Cohort, Phase 1/2 Study of Nivolumab Monotherpay and Nivolumab Combination Therapy in Subjects with Virus-Positive and Virus-Negative Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18902

A Randomized Double-Blind Phase 3 Study of Avelumab in Combination with Standard of Care Chemoradiotherapy (Cisplatin Plus Definitive Radiation Therapy) Versus Standard of Care Chemoradiotherapy in the Front-Line Treatment of Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Cancer Type: Head & Neck

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CLINICAL TRIAL18783

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18909

Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers

Cancer Type: Thoracic

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CLINICAL TRIAL18382

A Phase 1 Study of KB003 in Patients with Previously Treated Chronic Myelomonocytic Leukemia (CMML)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18596

A Phase II Study of Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer: Introduction of a Novel Form of Accelerated Partial Breast Radiotherapy

Cancer Type: Breast

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CLINICAL TRIAL18941

Preoperative Extended Chemotherapy vs. Chemotherapy Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Head of the Pancreas

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18079

Combination Immunotherapy with Herceptin and the HER2 Vaccine E75 in Low and Intermediate HER2-expressing Breast Cancer Patients to Prevent Recurrence

Cancer Type: Breast

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CLINICAL TRIAL18891

A Multinational Open-Label, Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Administrations of NKR-2 in Patients with Different Metastatic Tumor Types

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18890

Phase 3 Study of ADXS11-001 Administered Following Chemoradiation as Adjuvant Treatment for High Risk Locally Advanced Cervical Cancer: AIM2CERV (Advaxis IMmunotherapy 2 prevent CERVical recurrence)

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18950

A Phase I/Ib Study of Ipilimumab or Nivolumab in Patients with Relapsed Hematologic Malignancies after Allogeneic Hematopoietic Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19136

Randomized Phase II Study To Assess The Role Of Nivolumab As Single Agent To Eliminate Minimal Residual Disease And Maintain Remission In Acute Myelogenous Leukemia (AML) Patients After Chemotherapy (REMAIN TRIAL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19080

A Phase II Study of MLN0128 (TAK-228) in Relapsed and/or Refractory Acute Lymphoblastic Leukemia (ALL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18975

A Phase 2 Study of REGN2810, a Fully Human Monoclonal Antibody to Programmed Death-1, in Patients with Advanced Basal Cell Carcinoma who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy

Cancer Type: Cutaneous

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CLINICAL TRIAL18977

Phase 2 Study of the Safety, Efficacy, and Pharmacokinetics of G1T28 in Patients with Metastatic Triple Negative Breast Cancer Receiving Gemcitabine and Carboplatin Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL19112

DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18136

SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients with Advanced Sarcomas

Cancer Type: Sarcoma

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CLINICAL TRIAL18599

A Phase 2, International, Multicenter,Randomized, Open-Label, Parallel Group Study to Evaluate the Efficacy and Safety of CC-486 (Oral Azacitidine) Alone and in Combination with Durvalumab (Medi4736) in Subjects with Myelodysplastic Syndromes who Fail to Achieve an Objective Response to Treatment with Azacitidine for Injection or Decitabine

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18926

The National Myelodysplastic Syndromes (MDS) Study

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18914

Consolidative Ipilimumab and Nivolumab with Thoracic Radiotherapy after Platinum Based Chemotherapy for Patients with Extensive-Stage Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL19102

A Phase III, Multicenter, Randomized, Placebo-Controlled Study Of Atezolizumab (Anti−PD-L1 Antibody) As Monotherapy And In Combination With Platinum-Based Chemotherapy In Patients With Untreated Locally Advanced Or Metastatic Urothelial Carcinoma

Cancer Type: Genitourinary

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CLINICAL TRIAL19151

A Phase 3, Randomized Study to Assess the Efficacy and Safety of Ublituximab in Combination with TGR-1202 Compared to Obinutuzumab in Combination with Chlorambucil in Patients with Chronic Lymphocytic Leukemia (CLL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19089

Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (CHAMP)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19143

A Randomized, Multi-Center, Phase III Trial of Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus Host-Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18621

A Phase 1/2 Study of Talimogene laherparepvec in Combination with Neoadjuvant Chemotherapy in Triple Negative Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL19082

A Phase I/Ib Trial of Pirfenidone Combined with Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL19125

A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL19149

A Phase 1/2, Open Label, Multicenter Study To Assess The Safety And Tolerability Of Durvalumab (Anti-Pd-L1 Antibody) As Monotherapy And In Combination Therapy In Subjects With Lymphoma Or Chronic Lymphocytic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18083

Phase II Randomized Study of Lower Doses of Decitabine (DAC; 20 mg/m^2 IV daily for 3 days every month) versus Azacitidine (AZA; 75 mg/m^2 SC/IV daily for 3 days every month) versus Azcitidine (AZA; 75 mg/m^2 SC/IV daily for 5 days every month) in MDS Patients with Low and Intermediate-1 Risk Disease Transfusion-Dependent versus Best Supportive Care (BSC) in MDS Patients with Low and Intermediate-1 Risk Disease Transfusion-Independent

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19185

An Open Label, Single Arm Pilot Study of OncoSil, Administered to Subjects with Unresectable Locally Advanced Pancreatic Adenocarcinoma, Given in Combination with Gemcitabine or Gemcitabine+Nab-Paclitaxel Chemotherapies

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL19203

Reduced Intensity Conditioning for Haploidentical Bone Marrow Transplantation in Patients with Symptomatic Sickle Cell Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19181

Patient-Reported Outcomes in Immunotherapy for Head and Neck Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL19332

An Early Stage Biomarker Study of A Multi-Platform Analysis of a "Liquid Biopsy" of CSF in Patients with Leptomeningeal Disease and Other Brain Tumors To Improve Diagnosis and Treatment

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18994

Phase II Randomized Trial of Radiotherapy with or without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) with TP53 Sequencing

Cancer Type: Head & Neck

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CLINICAL TRIAL18610

A Phase I-II Study of Triciribine Phosphate Monohydrate (PTX-200) Plus Cytarabine in Refractory or Relapsed Acute Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19124

A Phase 3, Randomized Study of Adjuvant Immunotherapy with Nivolumab Combined with Ipilimumab Versus Ipilimumab or Nivolumab Monotherapy after Complete Resection of Stage IIIb/c/d or Stage IV Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL19230

Phase 2, Randomized, Open-Label Study Comparing Daratumumab, Lenalidomide, Bortezomib,and Dexamethasone (D-RVd) Versus Lenalidomide, Bortezomib, and Dexamethasone (RVd) in Subjects With Newly Diagnosed Multiple Myeloma Eligible for High-Dose Chemotherapy and Autologous Stem Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19322

A Phase 1b Trial of Hu5F9-G4 Monotherapy or Hu5F9-G4 in Combination with Azacitidine in Patients with Hematological Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18587

A Phase 2 Study of REGN2810, A Fully Human Monoclonal Antibody to Programmed Death 1(PD-1), in Patients with Advanced Cutaneous Squamous Cell Carcinoma

Cancer Type: Head & Neck

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