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CLINICAL TRIAL14690

Total Cancer Care Protocol: A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer

Cancer Type: Cancer Control

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CLINICAL TRIAL14882

Protocol for High-Risk Assessment, Screening, and Early Detection of Pancreatic Cancer at Moffitt Cancer Center

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL15769

Prospective Nipple-Areola Skin-Sparing Mastectomy

Cancer Type: Breast

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CLINICAL TRIAL16028

Transdisciplinary Research in Colorectal Cancer: Insulin-Like Growth Factor Axis and Colorectal Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL16480

Radiomics: A Prospective Study of Outcome in Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL16914

Sickness Behaviors in Gynecologic Cancer Patients Treated with Chemotherapy

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL16933

Older Breast Cancer Patients: Risk For Cognitive Decline

Cancer Type: Breast

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CLINICAL TRIAL16962

A Phase I Trial of Dose Escalation of Metformin in Combination with Vincristine, Irinotecan, and Temozolomide in Children with Relapsed or Refractory Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL17263

Phase I Trial of ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17676

A Multi-Center Biologic Assignment Trial Comparing Reduced Intensity Allogeneic Hematopoietic Cell Transplant to Hypomethylating Therapy or Best Supportive Care in Patients Age 50 or Older with Intermediate-2 and High Risk Myelodysplastic Syndrome

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17716

A Biomarker-related Approach to Screening for HPV-related Oropharyngeal Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL17723

Expansion of Enduring Infrastructure to Support Lung Cancer Screening Research

Cancer Type: Thoracic

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CLINICAL TRIAL17753

Focal Prostate Radio-Frequency Ablation for the Treatment of Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL17799

A Phase I Dose Escalation Trial of Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of the Head and Neck

Cancer Type: Head & Neck

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CLINICAL TRIAL17932

A Phase 1a/1b Trial of Trametinib in Combination with Sorafenib in Patients with Advanced Hepatocellular Cancer

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL17967

A Phase 1-2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-C19 in Subjects with Refractory Aggressive Non-Hodgkin Lymphoma (NHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17835

A Phase 3 Randomized, Placebo-Controlled Trial of Carboplatin and Paclitaxel With or Without the PARP Inhibitor Veliparib (ABT-888) in HER2-Negative Metastatic or Locally Advanced Unresectable BRCA-Associated Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL17933

A Randomized, Open-Label Study Comparing the Combination of YONDELIS and DOXIL/CAELYX With DOXIL/CAELYX Monotherapy for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18190

A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Assess the Efficacy and Safety of Farletuzumab (MORAb-003) in Combination with Carboplatin plus Paclitaxel or Carboplatin plus Peglyated Liposomal Doxorubicin (PLD) in Subjects with Low CA125 Platinum-Sensitive Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18492

A Single-arm, Phase 2 Study to Evaluate the Safety and Efficacy of VT-464 in Patients with Castration-Resistant Prostate Cancer Progressing on Enzalutamide or Abiraterone

Cancer Type: Genitourinary

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CLINICAL TRIAL17929

A Phase I/II, Multicenter, Open-label, Dose Escalation and Randomized Trial of BI 836858 in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17937

A Phase 1/2 Dose Escalation and Cohort Expansion Study of the Safety and Tolerability of Urelumab Administered in Combination with Nivolumab in Advanced /Metastatic Solid Tumors and B Cell Non-Hodgkins Lymphoma

Cancer Type: Cutaneous

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CLINICAL TRIAL18649

A Randomized Multicenter Phase II Trial to Evaluate the Safety and Immunogenicity of Two Doses of Vaccination with Folate Receptor Alpha Peptides with GM-CSF in Patients with Triple Negative Breast Cancer Defined as Primary Tumor that is Her2-neu Negative and Low (< 10%) ER/PR Nuclear Staining.

Cancer Type: Breast

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CLINICAL TRIAL18331

Selection of Allogeneic Hematopoietic Cell Donors Based on KIR and HLA Genotypes

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17938

A Phase II, Open-label, Multicenter Trial to Investigate the Clinical Activity and Safety of MSB0010718C in Subjects with Merkel Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL18435

Phase II study of Copanlisib (BAY 80-6946) in Combination with Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18509

A Phase 3 Randomized, Double-blind, Multi-center Study of Adjuvant Nivolumab versus Placebo in Subjects with High Risk Invasive Urothelial Carcinoma

Cancer Type: Genitourinary

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CLINICAL TRIAL18232

Addressing Tobacco Health Disparities via Group Intervention

Cancer Type: Healthy Subjects

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CLINICAL TRIAL18390

A Phase 1 Dose Escalation, Multicenter, Open-Label, Safety, Pharmacokinetic and Pharmacodynamic Study of FT-1101 In Patients With Relapsed or Refractory Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18345

A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients with Advanced Solid Tumors

Cancer Type: Genitourinary

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CLINICAL TRIAL17981

A Pilot Study of Adaptive Abiraterone Therapy for Metastatic Castration Resistant Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL18329

A Phase 1/2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Subjects with Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r ALL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18431

A Screening Protocol to Determine Tumor Antigen Expression and HLA Sub-Type for Eligibility Determination for Clinical Trials Evaluating the Safety and Efficacy of Autologous T Cells Expressing Enhanced TCRs in Subjects with Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL18395

Phase 1/2 Study Of Intratumoral G100 With Or Without Pembrolizumab In Patients With Follicular Non-Hodgkin's Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18430

Evaluation of Panobinostat (LBH589) as Maintenance Therapy in Multiple Myeloma Following Autologous Hematopoietic Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18611

The Gut Microbiome and Immunotherapy in Non-small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL18558

A Phase 1B/2 Open-Label Study to Evaluate Safety, Clinical Activity, Pharmacokinetics and Pharmacodynamics of Avelumab (MSB00100718C) in Combination with Other Cancer Immunotherapies in Patients with Advanced Malignancies

Cancer Type: Thoracic

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CLINICAL TRIAL18309

A Phase 2, Multicenter, Single-arm Study to Assess the Safety, Feasibility, and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-144) Followed by IL-2 for Treatment of Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL17773

A Phase 1 Study of the Safety and Pharmacokinetics of Escalating Doses of ASG-22CE Given as Monotherapy in Subjects with Metastatic Urothelial Cancer and Other Malignant Solid Tumors that Express Nectin-4

Cancer Type: Genitourinary

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CLINICAL TRIAL18744

A Phase I Trial of MEDI-570 in Patients with Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL) Follicular Variant and Angioimmunoblastic T-Cell Lymphoma (AITL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18346

Evaluating the Safety and Biological Activity of a Dendritic Cell Survivin Vaccine in Patients with Multiple Myeloma Undergoing Autologous Hematopoietic Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18522

A Phase I Dose Escalation Open Label Clinical Trial Evaluating the Safety and Efficacy of MAGE-A10c796T in Subjects with Stage IIIb or Stage IV Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL18615

A Phase I/ II Study to Evaluate the Safety and Preliminary Efficacy of Nivolumab in Combination with Brentuximab Vedotin in Subjects with Relapsed Refractory Non Hodgkin Lymphomas with CD30 Expression CheckMate 436: CHECKpoint pathway and nivolumab clinical Trail Evaluation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18684

A Phase II Investigator Sponsored Study of Nivolumab in Patients with Advanced Refractory Biliary Tract Cancers

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18515

Symptoms, Toxicity Prevalence and Quality of Life Benefit of Targeted Therapies and Immunotherapies in Lung Cancer Patients: An Observational Prospective Cohort Study within the Total Cancer Care Population

Cancer Type: Thoracic

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CLINICAL TRIAL18738

Developing a Patient- and Caregiver-Centered Psycho-Educational Tool to Support Recovery after Cystectomy

Cancer Type: Genitourinary

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CLINICAL TRIAL18682

Determinants of Age-Related Treatment Effectiveness in Ovarian Cancer: Prospective Study of Pharmacokinetics Patterns and Underlying Biology.

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18501

A Randomized,Placebo Controlled Phase 2b/3 Study of ABT 414 with Concurrent Chemoradiation and Adjuvant Temozolomide in Subjects with Newly Diagnosed Glioblastoma (GBM) with Epidermal Growth Factor Receptor (EGFR) Amplification (Intellance 1)

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18816

A Phase 1-2 Multi-Center Study Evaluating the Safety and Efficacy of KTE-C19 in Combination with Atezolizumab in Subjects with Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18523

A Validation Study on the Impact of Decipher® Testing on Treatment Recommendations in African-American and Non-African American Men with Prostate Cancer (VANDAAM Study)

Cancer Type: Genitourinary

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CLINICAL TRIAL18612

A Randomized Phase II/III Study of Adjuvant Concurrent Radiation and Chemotherapy versus Radiation Alone in Resected High-Risk Malignant Salivary Gland Tumors

Cancer Type: Head & Neck

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CLINICAL TRIAL17865

SL-401 in Patients with Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasm

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17651

Multi Institutional Phase II Trial of Single Agent Regorafenib in Refractory Advanced Biliary Cancers

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL17971

Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)

Cancer Type: Thoracic

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CLINICAL TRIAL18374

A Phase II Trial Evaluating the use of a Histone Deacetylase Inhibitor Panobinostat for Graft Versus Host Disease (GVHD) Prevention

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18613

Phase II Study of nab-Paclitaxel in Combination with Gemcitabine for Treatment of Recurrent/Refractory Sarcoma in Teenagers and Young Adults

Cancer Type: Sarcoma

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CLINICAL TRIAL18356

A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients who have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL17452

Patient Outcomes of a Self-Care Management Approach to Cancer Symptoms:A Clinical Trial

Cancer Type: Multiple

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CLINICAL TRIAL18574

A Randomized Phase 3 Open Label Study of Nivolumab vs Temozolomide Each in Combination with Radiation Therapy in Newly Diagnosed Adult Subjects with Unmethylated MGMT (tumor O-6-methylguanine DNA methyltransferase) Glioblastoma

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18386

A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL18855

Multicenter, Open-label, Phase 1, Dose-escalation,Cohort-expansion, First-in-Human Study of KHK2455 Administered as Monotherapy and in Combination with Mogamulizumab (KW-0761) in Adult Subjects with Locally Advanced or Metastatic Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18755

A Phase 2, Randomized Study of MLN0128 (a Dual TORC1/2 Inhibitor), MLN0128 + MLN1117 (a PI3Ka Inhibitor), Weekly Paclitaxel, or the Combination of Weekly Paclitaxel and MLN0128 in Women With Advanced, Recurrent, or Persistent Endometrial Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18555

A Randomized Phase II/III Trial of Prophylactic Cranial Irradiation with or without Hippocampal Avoidance for Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL18361

Brentuximab Vedotin Plus AD in Non-bulky Limited Stage Hodgkin Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18197

A Phase 2 Study of MM-121 in Combination with Docetaxel or Pemetrexed versus Docetaxel or Pemetrexed Alone in Patients with Heregulin Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL18503

STARTRK-2: An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients with Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements

Cancer Type: Thoracic

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CLINICAL TRIAL18686

An Observational Pilot Study to Compare the Compliance with and Health Related Quality of Life during Therapy with Standard High-Dose Interferon Alfa (Intron® A, HDI) versus Pegylated Alfa-Interferon 2b (Sylatron, PEG IFN) in Patients with Surgically Resected Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL18739

A Phase 1 Dose Escalation And Cohort Expansion Study Of ERY974, AN ANTI-GLYPICAN 3 (GPC3)/CD3 Bispecific Antibody, In Patients With Advanced Solid Tumors

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18289

A Phase 2 Multicenter Study Evaluating the Efficacy of KTE-C19 in Subjects with Relapsed/Refractory Mantle Cell Lymphoma (r/r MCL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18569

A Randomized, Controlled, Phase 3 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Melphalan/HDS Treatment in Patients with Hepatic-Dominant Ocular Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL18814

A Multi-Center, Phase II Trial of HLA-Mismatched Unrelated Donor Bone Marrow Transplantation with Post-Transplantation Cyclophosphamide for Patients with Hematologic Malignancies

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17974

An Open-Label, Multicenter, Dose-Escalation, Phase 1b/2 Study of the Safety, Efficacy, Pharmacodynamics, and Pharmacokinetics of RTA 408 in Combination With Ipilimumab or Nivolumab in the Treatment of Patients With Unresectable or Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL18342

A Pilot Open Label Clinical Trial Evaluating the Safety and Efficacy of Autologous T Cells Expressing Enhanced TCRs Specific for NY-ESO-1 in Subjects with Stage IIIb or Stage IV Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL17986

Phase 1 Study of Mogamulizumab (KW-0761) in Combination with MEDI4736 (Durvalumab) and Mogamulizumab in Combination with Tremelimumab in Subjects with Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18778

A Phase 3, Randomized, Open-Label Study To Evaluate the Efficacy and Safety of Eflornithine with Lomustine Compared to Lomustine Alone in Patients with Anaplastic Astrocytoma That Progress/Recur After Irradiation and Adjuvant Temozolomide Chemotherapy

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18398

Novartis Pharmaceuticals trial entitled: A phase II, multicenter, study of oral cMET inhibitor INC280 in adult patients with EGFR wild-type (wt), advanced non-small cell lung cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL17978

A Phase I Trial of Hypofractionated Stereotactic Irradiation (HFSRT) with MK-3475 and Bevacizumab in Patients with Recurrent High Grade Gliomas

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18119

A Phase 1b Study Evaluating the Safety, Tolerability and Immunogenicity of CMB305 (Sequentially Administered LV305 and G305) in Patients with Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1

Cancer Type: Sarcoma

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CLINICAL TRIAL18815

A Phase 2 Study of Tipifarnib in Subjects with Chronic Myelomonocytic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18876

A Phase 1/1b Open-Label Study to Determine the Safety and Tolerability of ALRN-6924 alone and in Combination with Cytarabine (Ara-C) in Patients with Relapsed/Refractory Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome with Wild-Type TP53

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18847

Increasing HPV Vaccination Series Completion Rates among Adolescent Hispanics in Tampa and Ponce

Cancer Type: Healthy Subjects

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CLINICAL TRIAL18094

A Phase 2 Study of Transarterial Chemoperfusion Treatment with Cisplatin, Methotrexate and Gemcitabine in Patients with Unresectable Pleural Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL18647

A Randomized Phase 2 Single Blind Study of Temozolomide plus Radiation Therapy combined with Nivolumab or Placebo in Newly Diagnosed Adult Subjects with MGMT-Methylated (tumor O6-methylguanine DNA methyltransferase) Glioblastoma

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18207

Phase 2 Trial of Dose Dense (Weekly) Paclitaxel with Pembrolizumab (MK-3475) in Platinum Resistant Recurrent Ovarian Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18321

Phase I/Ib trial of single agent PBF-509 and in combination with PDR001 for patients with advanced NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL18225

Efficacy of MBSR Treatment on Cognitive Impairment among Breast Cancer Survivors

Cancer Type: Breast

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CLINICAL TRIAL18495

Caregiver Relationship Quality and Communication in Advanced Cancer Care

Cancer Type: Multiple

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CLINICAL TRIAL18525

Community Research Registry

Cancer Type: Healthy Subjects

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CLINICAL TRIAL18350

A Pilot Study of Genetically Engineered NY-ESO-1 Specific NY-ESO-1c259T in HLA-A2+ Patients with Synovial Sarcoma

Cancer Type: Sarcoma

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CLINICAL TRIAL18165

A Phase 1, Open-Label, Multicenter Trial of Oral Azacitidine (CC-486) Plus R-Chop in Subjects with IPI 2 or More Previously Untreated Diffuse Large B-Cell Lymphoma or Grade 3B Follicular Lymphoma, or Transformed Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18322

A Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of BLU-554 in Patients with Hepatocellular Carcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL17790

A Randomized Phase II Study of Autologous Stem Cell Transplantation with Tadalafil and Lenalidomide Maintenance with or without Activated Marrow Infiltrating Lymphocytes (MILs) in High Risk Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18068

A Multi-Center Phase 2 Open-Label Study to Evaluate Safety and Efficacy in Subjects with Melanoma Metastatic to the Brain treated with Nivolumab in Combination with Ipilimumab followed by Nivolumab Monotherapy

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18916

A Phase 2 Study of Ibrutinib (PCI-32765) in Refractory Distant Metastatic Cutaneous Melanoma: Correlation of Biomarkers with Response and Resistance

Cancer Type: Cutaneous

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CLINICAL TRIAL18327

Improving Adolescent and Young Adult Cancer Survivorship

Cancer Type: Multiple

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CLINICAL TRIAL18304

A Phase II Trial of AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL18365

Preliminary Evaluation of an Internet-Assisted Cognitive Behavioral Intervention for Targeted Therapy Fatigue

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18406

A Phase 1 Study of AZD1775 in Combination with Belinostat in Relapsed and Refractory Myeloid Malignancies and Selected Untreated Patients with Acute Myeloid Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18217

Multicenter Phase II, Double-blind Placebo Controlled Trial of Maintenance Ixazomib after Allogeneic Hematopoietic Stem Cell Transplantation for High Risk Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18517

A Randomized, Open-Label, Active-Controlled, Phase II Study of Intravenous Anetumab Ravtansine (BAY 94-9343) or Vinorelbine in Patients with Advanced or Metastatic Malignant Pleural Mesothelioma Overexpressing Mesothelin and Progressed on First Line Platinum/Pemetrexed-Based Chemotherapy

Cancer Type: Thoracic

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CLINICAL TRIAL18858

A Phase 1/2a Open-Label Study to Determine the Safety and Tolerability of ALRN-6924 in Patients with Advanced Solid Tumors or Lymphomas Expressing Wild-Type p53 Protein

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18837

An Open-Label Study of Rovalpituzumab Tesirine in Subjects with Delta-Like Protein 3-Expressing Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL17908

Phase II/III Biomarker-Driven Master Protocol for Second Line Therapy of Squamous Cell Lung Cancer (Screening Step)

Cancer Type: Thoracic

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CLINICAL TRIAL18756

The Clinical Utility of a Blood-Based Multitranscriptome Assay as a Biomarker for Gastroenteropancreatic and Lung Neuroendocrine Tumors

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18766

A Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haploidentical Peripheral Blood Stem Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18906

A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an anti-TIM-3 Monoclonal Antibody, in Patients with Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL17682

A Phase 1B, Multi-Center, Open-Label Study of Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL17970

A Randomized Phase III Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Observation for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

Cancer Type: Thoracic

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CLINICAL TRIAL17969

Randomized Study of Erlotinib vs. Observation in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL18821

A Phase 1b Trial to Assess the Modulation of Biological Markers in Patients with Potentially Resectable Soft Tissue Sarcoma Treated with Olaratumab Monotherapy Followed by Olaratumab plus Doxorubicin Combination Therapy

Cancer Type: Sarcoma

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CLINICAL TRIAL18828

Smartphone-Based Assessment of Patient-Reported Outcomes Related to Receipt of Immunotherapy

Cancer Type: Head & Neck

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CLINICAL TRIAL18862

A Phase 1, Open-Label, Dose-Escalation Study to Evaluate the Safety and Tolerability of SGN-LIV1A in Patients with LIV-1-Positive Metastatic Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL18874

A Phase 1b/2 Study to Assess the Safety and Efficacy of HBI-8000 in Combination with Nivolumab in Patients with Advanced Solid Tumors Including Melanoma, Renal Cell Carcinoma (RCC) and Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Cutaneous

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CLINICAL TRIAL18915

A Phase 1 Trial of MLN0128 (TAK-228) in Combination with Osimertinib (AZD9291) in Advanced EGFR Mutation Positive Non-Small Cell Lung Cancer (NSCLC) After Progression on a Previous EGFR Tyrosine Kinase Inhibitor

Cancer Type: Thoracic

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CLINICAL TRIAL17690

A Phase I Trial of Single Agent Trametinib (GSK1120212) in Advanced Cancer Patients with Hepatic Dysfunction

Cancer Type: Multiple

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CLINICAL TRIAL18646

Phase I Study of Pre-operative Capecitabine and Lenvatinib with External Radiation Therapy in Locally Advanced Rectal Adenocarcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18675

Phase II Trial of FOLFIRINOX in Metastatic High Grade Gastroenteropancreatic Neuroendocrine Carcinomas

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18772

A Randomized Multicenter, Open-label, Phase 2 Study Evaluating the Efficacy and Safety of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Subjects with Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly (>= 65 years) Acute Myeloid Leukemia (AML) Subjects Not Eligible for Hematopoietic Stem Cell Transplantation (HSCT)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18396

A Phase III Clinical Trial Evaluating TheraSphere® in Patients with Metastatic Colorectal Carcinoma of the Liver who have Failed First Line Chemotherapy

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18643

Biobank for African American Prostate Cancer Research in Florida

Cancer Type: Genitourinary

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CLINICAL TRIAL18683

A Phase 3, Multinational, Randomized, Open-Label, Parallel-Arm Study of Avelumab (MSB0010718C) in Combination with Axitenib (INLYTA®) Versus Sunitinub (SUTENT®) Monotherapy in the First-Line Treatment of Patients with Advanced Renal Cell Carcinoma

Cancer Type: Genitourinary

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CLINICAL TRIAL18664

A Phase 2, Multi-Center Study of High Dose Chemotherapy with Autologous Stem Cell Transplant Followed by Maintenance Therapy with Romidepsin for the Treatment of T cell Non-Hodgkin's Lymphoma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18825

A Phase 1b, First-in-Human, Dose Escalation and Expansion Study of XMT-1522 in Patients with Advanced Breast Cancer and Other Advanced Tumors Expressing HER2

Cancer Type: Multiple

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CLINICAL TRIAL18680

A study of Intravesical Bacillus Calmette-Guerin (BCG) in Combination with ALT-803 in Patients with Non-Muscle Invasive Bladder Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL18832

A Platform Study Exploring the Safety, Tolerability, Effect on the Tumor Microenvironment, and Efficacy of INCB Combinations in Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18835

Phase III Randomized Clinical Trial of Lurbinectedin (PM01183)/Doxorubicin (DOX) versus Cyclophosphamide (CTX), Doxorubicin (DOX) and Vincristine (VCR) (CAV) or Topotecan as Treatment in Patients with Small-Cell Lung Cancer (SCLC) Who Failed One Prior Platinum-containing Line (ATLANTIS Trial)

Cancer Type: Thoracic

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CLINICAL TRIAL18878

A Single-Arm, Multicenter, Phase 2 Trial to Evaluate Efficacy and Safety of Lenvatinib in Combination with Everolimus in Subjects with Unresectable Advanced or Metastatic Non Clear Cell Renal Cell Carcinoma (nccRCC) Who Have Not Received any Chemotherapy for Advanced Disease

Cancer Type: Genitourinary

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CLINICAL TRIAL18999

Early Detection of Cancer Progression: Leveraging Team Science

Cancer Type: Thoracic

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CLINICAL TRIAL17361

A Phase I/IB Trial of MEK162 in Combination with Erlotinib in NSCLC Harboring KRAS or EGFR Mutation

Cancer Type: Thoracic

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CLINICAL TRIAL18677

XALT3: Phase 3 Randomized Study Comparing X-396 to Crizotinib in Anaplastic Lymphoma Kinase (ALK) Positive Non-Small Cell Lung Cancer (NSCLC) Patients

Cancer Type: Thoracic

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CLINICAL TRIAL18788

A Phase 2 Study of Check Point Inhibitor, Durvalumab (MEDI4736) for Bacillus Calmette-Guérin (BCG) Refractory Urothelial Carcinoma in Situ (CIS) of the Bladder

Cancer Type: Genitourinary

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CLINICAL TRIAL18826

A Phase 1 Study of ALKS 4230 in Subjects with Advanced Solid Tumors

Cancer Type: Genitourinary

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CLINICAL TRIAL18904

Contributors to and Correlates of Loneliness in Lung Cancer Patients

Cancer Type: Thoracic

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CLINICAL TRIAL18393

A Phase 1, Open-Label, Dose Escalation Study of MGA271 in Combination with Pembrolizumab in Patients with B7-H3-Expressing Melanoma, Squamous Cell Cancer of the Head and Neck, or Squamous Cell Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL18685

Phase I/II, First-in-Human, Dose-Escalation Study of X-396 in Patients with Advanced Solid Tumors and Expansion Phase in Patients with ALK+ Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL18763

A Randomized, Phase II, Multicenter, Open Label, Study Evaluating Sirolimus and Prednisone in Patients with Refined Minnesota Standard Risk, Ann Arbor 1/2 Confirmed Acute Graft-Versus-Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18093

A Phase 2 Study of Abemaciclib in Patients with Brain Metastases Secondary to Hormone Receptor Positive Breast Cancer

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18527

Non-Comparative, Open-Label, Multiple Cohort, Phase 1/2 Study of Nivolumab Monotherpay and Nivolumab Combination Therapy in Subjects with Virus-Positive and Virus-Negative Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18093

A Phase 2 Study of Abemaciclib in Patients with Brain Metastases Secondary to Hormone Receptor Positive Breast Cancer

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18527

Non-Comparative, Open-Label, Multiple Cohort, Phase 1/2 Study of Nivolumab Monotherpay and Nivolumab Combination Therapy in Subjects with Virus-Positive and Virus-Negative Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18786

A Phase 2, Randomized, Multi-institutional Study of Nivolumab and Ipilimumab versus Nivolumab, Ipilimumab and Stereotactic Body Radiation Therapy for Metastatic Merkel Cell Carcinoma

Cancer Type: Cutaneous

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CLINICAL TRIAL18902

A Randomized Double-Blind Phase 3 Study of Avelumab in Combination with Standard of Care Chemoradiotherapy (Cisplatin Plus Definitive Radiation Therapy) Versus Standard of Care Chemoradiotherapy in the Front-Line Treatment of Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Cancer Type: Head & Neck

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CLINICAL TRIAL18537

A Phase 1b/2 Dose Escalation and Cohort Expansion Study of the Safety, Tolerability and Efficacy of a Novel Transforming Growth Factor-B Receptor I Kinase Inhibitor (Galunisertib) Administered in Combination with Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumours (Phase 1b) and in Recurrent or Refractory Non-Small Cell Lung Cancer or Hepatocellular Carcinoma (Phase 2)

Cancer Type: Multiple

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CLINICAL TRIAL18871

A Phase II, Open-Label, Multicenter, Single-Arm Study to Investigate the Efficacy and Safety of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Patients with Stage IB, II, or IIIA Resectable and Untreated Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL19103

Screen to Save: NCI Colorectal Cancer Outreach & Screening Initiative

Cancer Type: Healthy Subjects

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CLINICAL TRIAL18537

A Phase 1b/2 Dose Escalation and Cohort Expansion Study of the Safety, Tolerability and Efficacy of a Novel Transforming Growth Factor-B Receptor I Kinase Inhibitor (Galunisertib) Administered in Combination with Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumours (Phase 1b) and in Recurrent or Refractory Non-Small Cell Lung Cancer or Hepatocellular Carcinoma (Phase 2)

Cancer Type: Multiple

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CLINICAL TRIAL18871

A Phase II, Open-Label, Multicenter, Single-Arm Study to Investigate the Efficacy and Safety of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Patients with Stage IB, II, or IIIA Resectable and Untreated Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL19103

Screen to Save: NCI Colorectal Cancer Outreach & Screening Initiative

Cancer Type: Healthy Subjects

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CLINICAL TRIAL18901

A Prospective, Open Label Phase I/II Study to Assess the Safety and Efficacy of Cycles of Intravenously Infused Doses of OPN-305 in Second-line Lower (Low and intermediate-1) Risk Myelodysplastic Syndrome (MDS)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18428

A Randomized Phase II Study of Individualized Combined Modality Therapy for Stage III Non-Small Cell Lung Cancer (NSCLC)

Cancer Type: Thoracic

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CLINICAL TRIAL18758

A Phase 1, Open-Label Dose Escalation Study of PF-04518600 as a Single Agent and in Combination with PF-05082566 in Patients with Selected Locally Advanced or Metastatic Carcinomas

Cancer Type: Thoracic

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CLINICAL TRIAL18940

The Complexity of Family-Centered Care: Identifying Support and Decision-Making Needs and Expectations of Young Adult Cancer Patients, Partner and Parent Caregivers

Cancer Type: Multiple

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CLINICAL TRIAL18062

Impact of Ancillary Techniques in the Pre-Surgical Diagnosis of Thyroid Nodules.

Cancer Type: Head & Neck

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CLINICAL TRIAL18783

A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18899

Alternative Dosing of Exemestane in Postmenopausal Women with Stage 0-II ER-Positive Breast Cancer: a Randomized Presurgical Trial

Cancer Type: Breast

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CLINICAL TRIAL18494

A Phase I/II Study of Pembrolizumab and Vorinostat in Patients with Immune Therapy Naïve and Immune Therapy Pretreated Stage IV NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL18561

A Clinical Trial of Pembrolizumab (MK-3475) Evaluating Predictive Biomarkers in Subjects with Advanced Solid Tumors (KEYNOTE 158)

Cancer Type: Multiple

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CLINICAL TRIAL18536

Coordinated High Dose Interleukin-2 (aldesleukin, Proleukin) and Pembrolizumab (anti-PD1, Keytruda) for Therapy of Metastatic Kidney Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL18939

An Open-label, Multicenter Phase 1 Trial to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Splicing Modulator H3B-8800 for Subjects With Myelodysplastic Syndromes, Acute Myeloid Leukemia, and Chronic Myelomonocytic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18989

A Phase 1b/2 Study of PV-10 Intralesional Injection in Combination with Systemic Immune Checkpoint Inhibition for Treatment of Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL17268

I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2)

Cancer Type: Breast

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CLINICAL TRIAL18205

A Study in Patients Treated with MM-398 to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment

Cancer Type: Breast

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CLINICAL TRIAL18909

Adjuvant Nivolumab in Resected Lung Cancers (ANVIL) A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers

Cancer Type: Thoracic

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CLINICAL TRIAL18201

A Phase I Dose Escalation Study of Preoperative Stereotactic Body Radiation Therapy (SBRT) for High Risk Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL18382

A Phase 1 Study of KB003 in Patients with Previously Treated Chronic Myelomonocytic Leukemia (CMML)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18596

A Phase II Study of Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer: Introduction of a Novel Form of Accelerated Partial Breast Radiotherapy

Cancer Type: Breast

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CLINICAL TRIAL18944

A Phase 2 Study to Evaluate the Safety, Tolerability and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-145) followed by IL-2 in Patients with Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck

Cancer Type: Head & Neck

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CLINICAL TRIAL18156

Phase 1b Study of Carfilzomib Administered Once Weekly in Combination with Lenalidomide and Dexamethasone in Subjects with Multiple Myeloma

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL18377

A Pilot Clinical Trial Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL18938

A Phase 1 Study Evaluating the Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*0401 Positive Subjects with Advanced Cancers

Cancer Type: Multiple

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CLINICAL TRIAL17814

Investigator-Initiated Phase I/II Clinical Trial of Selinexor (KPT-330) and Liposomal Doxorubicin for Relapsed and Refractory Multiple Myeloma

Cancer Type: Multiple Myeloma

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CLINICAL TRIAL18838

An Open Label, Randomized, Two Arm Phase III Study of Nivolumab in Combination with Ipilimumab versus Extreme Study Regimen (cetuximab + cisplatin/carboplatin + fluorouracil) as First Line Therapy in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Cancer Type: Head & Neck

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CLINICAL TRIAL18839

A Double-Blind, Randomized, Two Arm Phase 2 Study of Nivolumab in Combination with Ipilimumab versus Nivolumab in Combination with Ipilimumab Placebo In Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Cancer Type: Head & Neck

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CLINICAL TRIAL18928

A Phase III, Randomized, Open Label Trial of Nivolumab in combination with Ipilimumab versus Pemetrexed with Cisplatin or Carboplatin as First Line Therapy in unresectable Pleural Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL18941

Preoperative Extended Chemotherapy vs. Chemotherapy Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Head of the Pancreas

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18937

Pazopanib Neoadjuvant Trial in Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib

Cancer Type: Sarcoma

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CLINICAL TRIAL18660

Phase II Trial of SMO/AKT/NF2 Inhibitors in Progressive Meningiomas With SMO/AKT/NF2 Mutations

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18933

Phase II Study of Pembrolizumab and Ipilimumab Following Initial Anti-PD1/L1 Antibody

Cancer Type: Cutaneous

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CLINICAL TRIAL19001

A Phase 1a/1b Multicenter, Open Label, Dose-Finding Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of CWP232291 Administered Intravenously Either Alone or in Combination with Lenalidomide and Dexamethasone in Subjects with Relapsed or Refractory Myeloma (MM)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19003

A Randomized Phase 3 Trial of TRC105 and Pazopanib versus Pazopanib Alone In Patients with Advanced Angiosarcoma (TAPPAS)

Cancer Type: Sarcoma

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CLINICAL TRIAL18079

Combination Immunotherapy with Herceptin and the HER2 Vaccine E75 in Low and Intermediate HER2-expressing Breast Cancer Patients to Prevent Recurrence

Cancer Type: Breast

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CLINICAL TRIAL18420

Patient Navigation in the Adolescent and Young Adult (AYA) Cancer Population

Cancer Type: Sarcoma

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CLINICAL TRIAL18923

A Multi-Center Open-Label Phase 1/2 Study of BGB324 in Combination with Erlotinib in Patients with Stage IIIb or Stage IV Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL18959

A Phase 2 Study to Evaluate the Safety, Tolerability and Efficacy of Cell Transfer Therapy Using Autologous Tumor Infiltrating Lymphocytes (LN-145) followed by IL-2 in Patients with Recurrent and/or Metastatic Cervical Carcinoma

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL17985

A Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCB024360 in Combination With MEDI4736 in Subjects With Selected Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL19072

A Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects with Relapsed/Refractory Indolent Non-Hodgkin Lymphoma (iNHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18844

A Phase 2 Study of Cediranib in Combination with Olaparib in Advanced Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18891

A Multinational Open-Label, Dose Escalation Phase I Study to Assess the Safety and Clinical Activity of Multiple Administrations of NKR-2 in Patients with Different Metastatic Tumor Types

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18885

A Randomized, Double-Blind, Placebo-Controlled Phase III Study of ODM-201 Versus Placebo in Addition to Standard Androgen Deprivation Therapy and Docetaxel in Patients with Metastatic Hormone-Sensitive Prostate Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL19131

Contribution of Sleep Disruption and Physical Inactivity to Fatigue In Survivors of Allogeneic Hematopoietic Cell Transplant

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18890

Phase 3 Study of ADXS11-001 Administered Following Chemoradiation as Adjuvant Treatment for High Risk Locally Advanced Cervical Cancer: AIM2CERV (Advaxis IMmunotherapy 2 prevent CERVical recurrence)

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18539

A Randomized, Multicenter, Open-Label, Non-Inferiority, Phase 3 Study of ACP-196 Versus Ibrutinib in Previously Treated Subjects with High Risk Chronic Lymphocytic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18521

A Phase 1/2 Open-Label Study of the Safety, Tolerability and Efficacy of the Selective Inhibitor of Nuclear Export (SINE)Compound KPT-8602 in Patients with Relapsed/Refractory Cancer Indications

Cancer Type: Multiple

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CLINICAL TRIAL19067

A Phase 2 Single-arm Study to Evaluate Safety and Efficacy of CRS-207 with Pembrolizumab in Adults with Previously-Treated Malignant Pleural Mesothelioma

Cancer Type: Thoracic

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CLINICAL TRIAL18980

A Phase III, Multicenter, Randomized,Placebo-Controlled, Double-Blind Study of Atezolizumab (AntiPd-L1 Antibody) as Adjuvant Therapy in Patients with Renal Cell Carcinoma at High Risk of Developing Metastasis Following Nephrectomy

Cancer Type: Genitourinary

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CLINICAL TRIAL18950

A Phase I/Ib Study of Ipilimumab or Nivolumab in Patients with Relapsed Hematologic Malignancies after Allogeneic Hematopoietic Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19136

Randomized Phase II Study To Assess The Role Of Nivolumab As Single Agent To Eliminate Minimal Residual Disease And Maintain Remission In Acute Myelogenous Leukemia (AML) Patients After Chemotherapy (REMAIN TRIAL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18630

Phase 1/2 Investigator Sponsored Study of Selinexor in Combination with High-Dose Melphalan Before Autologous Hematopoietic Cell Transplantation for Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19080

A Phase II Study of MLN0128 (TAK-228) in Relapsed and/or Refractory Acute Lymphoblastic Leukemia (ALL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18051

A Phase 1, First-in-Human, Open Label, Dose Escalation Study of MGD007, A Humanized gpA33 x CD3 Dual-Affinity Re-Targeting (DART) Protein in Patients with Relapsed/Refractory Metastatic Colorectal Carcinoma

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18975

A Phase 2 Study of REGN2810, a Fully Human Monoclonal Antibody to Programmed Death-1, in Patients with Advanced Basal Cell Carcinoma who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy

Cancer Type: Cutaneous

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CLINICAL TRIAL18811

Randomized, Double-Blind, Phase 2/3 Study in Subjects with Malignant Pleural Mesothelioma with Low Argininosuccinate Synthetase 1 Expression to Assess ADI-PEG 20 with Pemetrexed and Cisplatin (ATOMIC-Meso Phase 2/3 Study)

Cancer Type: Thoracic

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CLINICAL TRIAL18977

Phase 2 Study of the Safety, Efficacy, and Pharmacokinetics of G1T28 in Patients with Metastatic Triple Negative Breast Cancer Receiving Gemcitabine and Carboplatin Chemotherapy

Cancer Type: Breast

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CLINICAL TRIAL18804

Phase 1-2 Study Of Medi4736 Alone or in Combination With Adxs11-001 In Recurrent/Persistent or Metastatic Cervical or HPV + Head & Neck Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL18986

TRITON2: A Multicenter, Open-label Phase 2 Study of Rucaparib in Patients with Metastatic Castration-resistant Prostate Cancer Associated with Homologous Recombination Deficiency.

Cancer Type: Genitourinary

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CLINICAL TRIAL19101

A Phase 1/2a Study of BMS-986205 Administered in Combination with Nivolumab anti-PD-1 Monoclonal Antibody) and in Combination with Both Nivolumab and Ipilimumab (anti-CTLA-4 Monoclonal Antibody) in Advanced Malignant Tumors

Cancer Type: Thoracic

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CLINICAL TRIAL19112

DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors

Cancer Type: Multiple

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CLINICAL TRIAL18787

A Phase III, Open Label Study to Evaluate the Safety and Efficacy of Instiladrin (rAd-IFN/Syn3)Administered Intravesically to Patients with High Grade, BCG Unresponsive Non-Muscle Invasive Bladder Cancer

Cancer Type: Genitourinary

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CLINICAL TRIAL18136

SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients with Advanced Sarcomas

Cancer Type: Sarcoma

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CLINICAL TRIAL18599

A Phase 2, International, Multicenter,Randomized, Open-Label, Parallel Group Study to Evaluate the Efficacy and Safety of CC-486 (Oral Azacitidine) Alone and in Combination with Durvalumab (Medi4736) in Subjects with Myelodysplastic Syndromes who Fail to Achieve an Objective Response to Treatment with Azacitidine for Injection or Decitabine

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18880

A Phase 2, Open-label, Single-arm, Two-cohort Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) or Relapsed/Refractory Primary Testicular Lymphoma (PTL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18973

A Phase 1b/2 Study to Evaluate the Safety and Efficacy of APR-246 in Combination with Azacitidine for the Treatment of TP53 Mutant Myeloid Neoplasms

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18926

The National Myelodysplastic Syndromes (MDS) Study

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18626

Carfilzomib for Treatment of Chronic Graft vs. Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18789

A Randomized Phase 2 Trial of Neoadjuvant and Adjuvant Therapy with the IRX-2 Regimen in Patients with Newly Diagnosed Stage II, III or IVA Squamous Cell Carcinoma of the Oral Cavity

Cancer Type: Head & Neck

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CLINICAL TRIAL18914

Consolidative Ipilimumab and Nivolumab with Thoracic Radiotherapy after Platinum Based Chemotherapy for Patients with Extensive-Stage Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL18982

The Roles of Education and Patient Engagement to Improve Symptom Management and the Quality of Life for Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19068

Refinement of an Assessment Tool to Identify Cancer Survivorship Needs

Cancer Type: Multiple

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CLINICAL TRIAL19079

A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of Oprozomib in Combination with Pomalidomide and Dexamethasone in Subjects with Relapsed or Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19100

Prospective Comparative Effectiveness Trial for Malignant Bowel Obstruction

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL19114

Phase 1/2 Study to Evaluate the Safety and Preliminary Efficacy of Nivolumab Combined with Daratumumab in Participants with Advanced or Metastatic Solid Tumors

Cancer Type: Multiple

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CLINICAL TRIAL19209

Combined Imaging and Blood Biomarkers for Breast Cancer Diagnosis

Cancer Type: Healthy Subjects

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CLINICAL TRIAL19093

Open-Label Randomized Pilot Study to Assess the Safety, Tolerability and Antitumor Activity of Genetically Engineered NY-ESO-1 Specific (c259) T Cells Alone or in Combination with Pembrolizumab in HLA-A2+ Subjects with NY-ESO-1 and/or LAGE-1a Positive Relapsed and Refractory Multiple Myeloma

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19102

A Phase III, Multicenter, Randomized, Placebo-Controlled Study Of Atezolizumab (Anti&#8722;PD-L1 Antibody) As Monotherapy And In Combination With Platinum-Based Chemotherapy In Patients With Untreated Locally Advanced Or Metastatic Urothelial Carcinoma

Cancer Type: Genitourinary

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CLINICAL TRIAL19083

A Phase 1b/2, Open-Label, Randomized Study of Daratumumab Administered in Combination with Atezolizumab Compared with Atezolizumab Alone in Subjects with Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL19151

A Phase 3, Randomized Study to Assess the Efficacy and Safety of Ublituximab in Combination with TGR-1202 Compared to Obinutuzumab in Combination with Chlorambucil in Patients with Chronic Lymphocytic Leukemia (CLL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19089

Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (CHAMP)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19119

A Single-Cohort, Phase 2 Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18671

Facilitating Smoking Cessation with Reduced Nicotine Cigarettes

Cancer Type: Healthy Subjects

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CLINICAL TRIAL18964

Randomized Double-Blind Phase III Study of Ibrutinib During and Following Autologous Stem Cell Transplantation Versus Placebo in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma of the Activated B-cell Subtype

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19070

A Multicenter, Open-label, Expanded Access Study of Axicabtagene Ciloleucel for the Treatment of Relapsed/Refractory Transplant-Ineligible Aggressive Non-Hodgkin Lymphoma (NHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19105

A Phase 1b Study of Safety and Immune Response to PVX-410 Vaccine Alone and in Combination with an Antibody Targeting the PD-1/PD-L1 Pathway in HLA-A2+ Subjects Who Have Completed Initial Standard Treatment of Stage II or III Triple Negative Breast Cancer (TNBC)

Cancer Type: Breast

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CLINICAL TRIAL19143

A Randomized, Multi-Center, Phase III Trial of Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus Host-Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18141

Phase II Study of Ibrutinib in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18930

A Phase I Trial of the Combination of Lenalidomide and Blinatumomab in Patients with Relapsed or Refractory Non-Hodgkins Lymphoma (NHL)

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19130

Expanded Access Protocol for Therapeutic Use of 177Lu-DOTA0-Tyr3-Octreotate in Patients with Inoperable, Somatostatin Receptor Positive, Midgut Carcinoid Tumors, Progressive under Somatostatin Analogue Therapy.

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18621

A Phase 1/2 Study of Talimogene laherparepvec in Combination with Neoadjuvant Chemotherapy in Triple Negative Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL19082

A Phase I/Ib Trial of Pirfenidone Combined with Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC

Cancer Type: Thoracic

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CLINICAL TRIAL19125

A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer

Cancer Type: Gynecological Tumor

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CLINICAL TRIAL19149

A Phase 1/2, Open Label, Multicenter Study To Assess The Safety And Tolerability Of Durvalumab (Anti-Pd-L1 Antibody) As Monotherapy And In Combination Therapy In Subjects With Lymphoma Or Chronic Lymphocytic Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL18597

Phase I Study of Escalating Doses of XL888 with Vemurafenib plus Cobimetinib for Patients with Unresectable BRAF Mutated Stage III/IV Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL18083

Phase II Randomized Study of Lower Doses of Decitabine (DAC; 20 mg/m^2 IV daily for 3 days every month) versus Azacitidine (AZA; 75 mg/m^2 SC/IV daily for 3 days every month) versus Azcitidine (AZA; 75 mg/m^2 SC/IV daily for 5 days every month) in MDS Patients with Low and Intermediate-1 Risk Disease Transfusion-Dependent versus Best Supportive Care (BSC) in MDS Patients with Low and Intermediate-1 Risk Disease Transfusion-Independent

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19185

An Open Label, Single Arm Pilot Study of OncoSil, Administered to Subjects with Unresectable Locally Advanced Pancreatic Adenocarcinoma, Given in Combination with Gemcitabine or Gemcitabine+Nab-Paclitaxel Chemotherapies

Cancer Type: Gastrointestinal Tumor

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CLINICAL TRIAL18979

A Phase II Multiple-Arm, Open-Label, Randomized Study of PARP inhibition (veliparib; ABT-888) and Anti-PD-L1 Therapy (atezolizumab; MPDL3280A) Either alone or in Combination in Homologous DNA Repair (HDR) Deficient Triple Negative Breast Cancer (TNBC)

Cancer Type: Breast

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CLINICAL TRIAL18936

A Phase I-II Study of Interferon-gamma Plus Weekly Paclitaxel, Trastuzumab and Pertuzumab in Patients with HER-2 Positive Breast Cancer

Cancer Type: Breast

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CLINICAL TRIAL19203

Reduced Intensity Conditioning for Haploidentical Bone Marrow Transplantation in Patients with Symptomatic Sickle Cell Disease

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19181

Patient-Reported Outcomes in Immunotherapy for Head and Neck Cancer

Cancer Type: Head & Neck

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CLINICAL TRIAL19332

An Early Stage Biomarker Study of A Multi-Platform Analysis of a "Liquid Biopsy" of CSF in Patients with Leptomeningeal Disease and Other Brain Tumors To Improve Diagnosis and Treatment

Cancer Type: Neurologic Oncology

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CLINICAL TRIAL18963

A Phase III, Open Label, Randomized Study to Assess the Efficacy and Safety of Olaparib (Lynparza) Versus Enzalutamide or Abiraterone Acetate in Men with Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment with a New Hormonal Agent and Have Homologous Recombination Repair Gene Mutations (Profound)

Cancer Type: Genitourinary

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CLINICAL TRIAL18994

Phase II Randomized Trial of Radiotherapy with or without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) with TP53 Sequencing

Cancer Type: Head & Neck

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CLINICAL TRIAL19122

A Phase I Clinical Trial Combining Nivolumab and Tumor Infiltrating Lymphocytes (TIL) for Patients with Advanced Non-Small Cell Lung Cancer

Cancer Type: Thoracic

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CLINICAL TRIAL18610

A Phase I-II Study of Triciribine Phosphate Monohydrate (PTX-200) Plus Cytarabine in Refractory or Relapsed Acute Leukemia

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19124

A Phase 3, Randomized Study of Adjuvant Immunotherapy with Nivolumab Combined with Ipilimumab Versus Ipilimumab or Nivolumab Monotherapy after Complete Resection of Stage IIIb/c/d or Stage IV Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL19310

A Phase III, Open-Label, Multicenter,Two-Arm, Randomized Study To Investigate The Efficacy And Safety Of Cobimetinib Plus Atezolizumab Versus Pembrolizumab In Patients With Previously Untreated Advanced Brafv600 Wild-Type Melanoma

Cancer Type: Cutaneous

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CLINICAL TRIAL18810

Phase 1b Study To Assess The Safety, Tolerability, and Clinical Activity of Gedatolisib in Combination with Palbociclib and Either Letrozole Or Fulvestrant in Women with Metastatic or Locally Advanced/Recurrent Breast Cancer (Mbc)

Cancer Type: Breast

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CLINICAL TRIAL19237

An Open-Label, Single-Arm, Phase 2 Study Of Avb-620 In Women With Primary, Nonrecurrent Breast Cancer Undergoing Surgery

Cancer Type: Breast

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CLINICAL TRIAL19230

Phase 2, Randomized, Open-Label Study Comparing Daratumumab, Lenalidomide, Bortezomib,and Dexamethasone (D-RVd) Versus Lenalidomide, Bortezomib, and Dexamethasone (RVd) in Subjects With Newly Diagnosed Multiple Myeloma Eligible for High-Dose Chemotherapy and Autologous Stem Cell Transplantation

Cancer Type: Malignant Hematology

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CLINICAL TRIAL19109

A Phase 1/2, Open-label, Multicenter, Dose Escalation and Dose Expansion Study of NKTR-214 and Nivolumab in Patients with Select Locally Advanced or Metastatic Solid Tumor Malignancies

Cancer Type: Genitourinary

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CLINICAL TRIAL19320

An Open-Label, Multicenter Extension Study In Patients Previously Enrolled In A Genentech and/or F Hoffmann La Roche Ltd. Sponsored Atezolizumab Study

Cancer Type: Thoracic

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CLINICAL TRIAL19322

A Phase 1b Trial of Hu5F9-G4 Monotherapy or Hu5F9-G4 in Combination with Azacitidine in Patients with Hematological Malignancies

Cancer Type: Malignant Hematology

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